Clinical trials: Neurology
Blood Pressure
Multidisciplinary Study to Verify Blood Pressure Documentation and Response to Titration of Intravenous Medications
This study is an observational, non-randomized, study that will examine the variability in blood pressure (BP) response to intravenous (IV) vasoactive medications when BP is continuously sampled versus real-world BP sampling.
- Trial name
- VERBATIM (NCT06253780)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Texas Southwestern Medical Center
Stroke, Relatives
Survey of Lifelong Food and Nutrition Assistance (LIFANA) in Stroke Patients and Caregivers
Many elderly suffer from nutritional problems that can cause (or can be caused by) a number of complications such as weakened immune systems and chronic health conditions (diabetes type 2, high blood pressure, cardiovascular…
- Conditions
- Stroke, Relatives, Diet Modification
- Trial name
- NCT03635476
- Testing
- Qualitative interview study
- Where
- Switzerland
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Cereneo AG
Migraine, Migraine Disease
Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine Attack Using VAS Score Among Patients Attending Headache and Neurology Outpatients Clinic of Ainshams University Hospitals
Caffeine extracted from green tea to abort acute attack of Migraine
- Conditions
- Migraine, Migraine Disease, Migraine Headache, Migraine Headache, With or Without Aura
- Trial name
- NCT07022496
- Testing
- Caffeine (200 mg), triptans, NSAID (Nonsteroidal anti-inflammatory drugs)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Alzheimer Disease
Imaging Biomarkers in Preclinical and Symptomatic AD
The purpose of this research study is to evaluate adult children of parents with and without Alzheimer's disease which represent an ideal population for investigating the biological changes that precede the clinical onset of AD.
- Trial name
- ACS_PIB_IND (NCT04134923)
- Testing
- [11C] Pittsburgh Compound-B (PIB)
- Where
- United States
- Volunteers
- 375 people
- Sponsor
- Tammie L. S. Benzinger, MD, PhD
Neurology Department
Abnormal Hyperkinetic Movements Post Acute Stroke
The occurrence of abnormal movements is a frequent reason for consultation in neurology. The etiologies are broadly separated into "primary causes", intrinsically neurological diseases (of genetic or degenerative origin), and…
- Trial name
- NCT05388552
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Cluster Headache, Trigeminal Autonomic Cephalalgias
Efficacy of Erenumab in Chronic Cluster Headache
The main purpose of this study is to evaluate the efficacy of erenumab in participants with chronic cluster headache.
- Conditions
- Cluster Headache, Trigeminal Autonomic Cephalalgias, Headache Disorders, Primary, Brain Disease
- Trial name
- CHERUB01 (NCT04970355)
- Testing
- Erenumab
- Where
- 11 sites in Germany
- Volunteers
- 101 people
- Sponsor
- Charite University, Berlin, Germany
Thrombus, Brain, Thrombosis
Thrombus Imaging and Treatment Analytics in Neurology
In the present study, the investigators use high-resolution MR vessel wall imaging, and select patients with cerebral and cervical artery occlusion to investigate the relationship between the imaging appearance of thrombus and…
- Trial name
- Titan (NCT05663281)
- Testing
- thrombus imaging appearance
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
COVID-19-Associated Encephalitis, Long COVID
Longterm Influence of Pediatric Long COVID Syndrome
We enroll pediatric patients who were diagnosed COVID-19 for main observation target. We will perform brain MRI and neuropsychiatric evaluation 4-6 months after COVID-19 diagnosed.
- Trial name
- NCT05566392
- Testing
- Brain MRI
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Acute Stroke
Evaluation of the Intravenous Tissue Plasminogen Activator Treatment Algorithm of Nursing Intern Students
Intravenous (IV) tissue plasminogen activator (tPA) is one of the key elements of acute ischemic stroke. In this study, acute stroke patients maximum benefit from the treatment, intravenous tissue plasminogen activator (IV tPA)…
- Trial name
- NCT05462665
- Testing
- theory training, theory and simulation training
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Dokuz Eylul University
Parkinsons Disease (PD)
Neuroimaging of Parkinson's
Parkinson's Disease (PD) is a neurodegenerative disorder caused by dysfunction in both subcortical structures and the cortex. The investigators recently discovered a new brain system called the Somato-Cognitive Action Network…
- Trial name
- NCT07024875
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Stroke
Structurally Reorganizing Motor Cortex in Stroke Patients Through Hebbian-type Stimulation
Stroke is a leading cause of morbidity in the United States but identification of treatment strategies to improve outcome is limited by the incomplete understanding of the mechanisms of recovery.
- Trial name
- NCT01569607
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Cathrin Buetefisch
Hypotension, Orthostatic
A Phase IV Study in Subjects With Neurogenic Orthostatic Hypotension
We are seeking male and female patients to voluntarily take part in a clinical research study. Patients must be aged 18 or older and diagnosed with symptomatic orthostatic hypotension (low blood pressure while in the upright…
- Trial name
- NCT00046163
- Testing
- midodrine hydrochloride (ProAmatine®)
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Shire
Chronic Headache
Direct Access to MRI and Neurology Referrals for the Management of Patients With Chronic Headache.
This study aims to evaluate whether direct access from General Practitioners (GPs) to Magnetic Resonance Imaging (MRI) for patients with chronic headache decreases overall NHS costs and increases patient satisfaction compared to…
- Trial name
- NCT02753933
- Testing
- MRI scan, Neurology Appointment
- Where
- United Kingdom
- Volunteers
- 296 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Mental Health, Neurology
Implementing Evidence in the Detection and Treatment of Post Stroke Depression
Post Stroke Depression (PSD)is a high volume condition with negative impact on patient recovery after stroke. The primary aim of this study is to evaluate the effectiveness of a system intervention to improve the proportion of…
- Conditions
- Mental Health, Neurology, Health Services
- Trial name
- NCT00296140
- Testing
- self management of PSD symptoms, screening and treatment of PSD
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- VA Office of Research and Development
Other Diagnoses and Conditions
Traditional Chinese Medicine Syndrome Identification in Paediatric Neurology
Traditional Chinese Medicine (TCM) has a history of more than two millenniums. It has been a common practice in China, Taiwan, Japan and Korea and is becoming increasingly popular worldwide in recent decades However, there is no…
- Trial name
- NCT01335282
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Neurology, Immunology
Clinical Relationship Between Vitamin D-mediated Th17 and Treg Cells and Parkinson's Disease
The aim of this study is to detect the expression levels of vitamin D, Treg, and Th17 in the peripheral blood of patients with Parkinson\'s disease (PD), investigate the impact of Treg/Th17 imbalance on PD patients, and…
- Trial name
- NCT06539260
- Testing
- Vitamin D
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Suzhou Municipal Hospital of Anhui Province
Main Heading (Descriptor) Terms
Mid-and Long-term Efficacy of Ergot Alkaloids in the Treatment of Salivation in Patients With Parkinson's Disease.
Parkinson's disease is the second most common neurodegenerative disease after Alzheimer's disease, the incidence of population over 60 years old in China is 1.37%, Parkinson's disease is often accompanied by various non-motor…
- Trial name
- NCT06035913
- Testing
- Dihydroergot mesylate
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Conversion Disorder, Parkinson Disease
Observational Study on "Functional Overlay" in Patients With Movement Disorders
The goal of this observational study is to learn about functional neurological disorders in patients with common non-functional movement disorders ("functional overlay").
- Conditions
- Conversion Disorder, Parkinson Disease, Tremor, Dystonia
- Trial name
- NCT05943652
- Testing
- Neurological examination, Anamnesis, Neuropsychological testing
- Where
- Austria
- Volunteers
- 216 people
- Sponsor
- Medical University of Graz
Parkinson Disease(PD)
A Smartphone Application for Neurology and Telemedicine
This observational research study is designed to assess the feasibility of developing a new software application that can be used in the home using a commercially available camera to measure abnormal body movements associated…
- Trial name
- NeuroVision (NCT06245174)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Altec Inc.
Traumatic Brain Injury
Growth Hormone or Sildenafil as Therapies for Fatigue in Mild- Traumatic-brain-injury (MTBI)
The overall goal is to determine whether perceptual or performance fatigue can be reduced in MTBI patients with and without growth hormone (GH) deficiency by treating them in a crossover fashion based upon GH status.
- Trial name
- NCT02114775
- Testing
- Growth Hormone, Sildenafil
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- The University of Texas Medical Branch, Galveston