Clinical trials: Neuromuscular Block
Endotracheal Intubation, Hemodynamics
Endotracheal Intubation Using Bonfils Fibrescope Without Neuromuscular Blockade
We studied intubating conditions and hemodynamic changes during endotracheal intubation employing either Bonfils intubating fiberscope or the conventional Macintosh laryngoscopy in 80 healthy patients candidates for elective…
- Conditions
- Endotracheal Intubation, Hemodynamics, Neuromuscular Blockade
- Trial name
- NCT00620386
- Testing
- Bonfils, Macintosh
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Tehran University of Medical Sciences
Urinary Retention Postoperative, Laparoscopic Cholecystectomy
Postoperative Urinary Retention After Reversal of Neuromuscular Block by Neostigmine Versus Sugammadex
This study is intended to be a single-site, prospective, randomized, controlled study that intends to enroll a total of 230 patients undergoing laparoscopic cholecystectomy at Parkland Hospital.
- Conditions
- Urinary Retention Postoperative, Laparoscopic Cholecystectomy, Neuromuscular Blockade, Sugammadex
- Trial name
- NCT05794503
- Testing
- Neostigmine, Sugammadex
- Where
- United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Neuromuscular Block, Surgery
MRI Measurement of the Effects of Deep Neuromuscular Blockade on the Abdominal Working Space During Laparoscopy
During laparoscopy, a surgical working space is obtained by creation of a pneumoperitoneum. Optimal surgical conditions are essential to ensure the patient's safety.
- Trial name
- RELAX-2 (NCT03287388)
- Testing
- No Rocuronium, Rocuronium (moderate NMB), Rocuronium (deep NMB)
- Volunteers
- 8 people
- Sponsor
- Radboud University Medical Center
Peripheral Nerve Injuries
Prospective Comparison of Adductor Canal Block Performed With a Multiport Versus Single Bevel Needle
Early ambulation after knee replacement surgery is made possible in large part by providing safe and effective pain control. Peripheral nerve blocks are increasingly used for postoperative analgesia since they can provide…
- Trial name
- NCT02786888
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Utah
Amyotrophic Lateral Sclerosis, Respiratory Function
The Safety and Effectiveness of Cholinergic Receptor Block Therapy in the Treatment of ALS
Thirty cases of amyotrophic lateral sclerosis patients were recruited from the neurology department of Ruijin Hospital, the pain department and the encephalopathy center of Luwan Branch of Ruijin Hospital.
- Conditions
- Amyotrophic Lateral Sclerosis, Respiratory Function, Scopolamine
- Trial name
- NCT04391361
- Testing
- Scopolamine, atropine, edaravone and dexmedetomidine, Edaravone
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Ruijin Hospital
Neuromuscular Blockade
Ephedrine for Reducing Onset Time of Rocurinium in Elderly Patients
The aim of this study is to determine the onset time of rocuronium after administration of ephedrine 0.15 mg/kg in patients with age ≥ 80 years.
- Trial name
- NCT06681662
- Testing
- Ephedrine Hydrochloride 30 mg/ml
- Where
- 2 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- Matias Vested
Residual Neuromuscular Block (TOF-ratio of 0.2)
Sugammadex and Neostigmine at Residual Neuromuscular Blockade
This study is designed to compare recovery times after reversal of a residual neuromuscular block (TOF-ratio 0.2) with different doses of either neostigmine or sugammadex.
- Trial name
- SUNDRO20 (NCT01006720)
- Testing
- Sugammadex, Neostigmine, Saline
- Where
- Germany
- Volunteers
- 99 people
- Sponsor
- Technical University of Munich
Obesity, Bariatric Surgery Candidate
Quality Assessment of Orotracheal Intubation Without Neuromuscular Blocking Agents in Obese Patients
This study will assess the condition of orotracheal intubation in obese patients undergoing an elective bariatric surgery without the use of neuromuscular blocking agents.
- Conditions
- Obesity, Bariatric Surgery Candidate, Intubation Complication
- Trial name
- OBEREM (NCT05026125)
- Testing
- Remifentanil Injection, Remifentanil Injection plus 30%
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Toulouse
Chronic Pain, Complex Regional Pain Syndromes
The Success of Lumbar Sympathetic Ganglion Block Using Lower Extremity Perfusion Index
The patient, who is experiencing chronic pain in the lower extremities persisting for more than three months, is scheduled to undergo lumbar sympathetic ganglion block.
- Conditions
- Chronic Pain, Complex Regional Pain Syndromes, Peripheral Neuropathy, Post Herpetic Neuralgia
- Trial name
- NCT06241820
- Testing
- Lumbar Sympathetic Ganglion Block
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Jeongsoo Kim
Neuropathic Pain, Neuropathic Pain Diagnostic Questionnaire (DN4) ≥ 4
Hematological Indices and Sympathetic Block Response in Neuropathic Pain
This prospective observational study aims to evaluate the relationship between hematological inflammatory indices and clinical treatment response in patients with neuropathic pain undergoing sympathetic nerve block procedures as…
- Trial name
- HINSPAIN (NCT07596823)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Laryngoscopy, Anesthesic Aduction
Comparison Between the Neuromuscular Blockade Onset Monitoring and the Expectation of a Fixed Delay After Curarization on the Quality of Laryngoscopy During Intubation in Elective Surgery (MONITURARE)
During anesthetic induction, the relevance of neuromuscular blockade (NMB) onset monitoring cannot be asserted and its superiority over waiting for a fixed delay (corresponding to pharmacokinetic knowledge of the neuromuscular…
- Conditions
- Laryngoscopy, Anesthesic Aduction, Neuromuscular Blockade, Monitoring
- Trial name
- MONITURARE (NCT03981042)
- Testing
- Monitoring
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Poitiers University Hospital
Residual Neuromuscular Blockade
Predictor of Residual Neuromuscular Blockade in Recovery Room After General Anesthesia
Background When general anesthesia was performed, neuromuscular blocking agents (NMBAs) are frequently used for facilitate tracheal intubation and keep patient still and relax during surgery.
- Trial name
- NCT02146859
- Where
- Thailand
- Volunteers
- 222 people
- Sponsor
- Mahidol University
Anesthesia, Neuromuscular Blockade
International Focus Group Discussion on Neuromuscular Monitoring.
Focus-Group based discussion designed to gain more in-depth information on factors that could lead to an increase in the adoption of neuromuscular monitoring taking into account different country-specific contexts.
- Conditions
- Anesthesia, Neuromuscular Blockade, Neuromuscular Block, Residual, Perioperative/Postoperative Complications
- Trial name
- NCT06945341
- Testing
- Focus-Group discussion
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Obesity
Comparison of Acceleromyography and Electromyography in Obese Patients Undergoing General Anesthesia
The goal of this prospective observational study is to compare two different methods of monitoring muscle relaxation during anesthesia - acceleromyography (AMG) and electromyography (EMG) - in people with obesity who are having…
- Trial name
- OBAEG (NCT07283354)
- Testing
- Neuromuscular monitoring with electromyography (EMG), Neuromuscular monitoring with acceleromyography (AMG)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Padova
Postoperative Residual Curarization
Postoperative Residual Paralysis After Cardiac Surgery
The main objective of this study is to describe the incidence of postoperative residual paralysis (mean train-of-four <90%) when weaning from the ventilator in patients admitted to the Intensive Care Unit (ICU) after elective…
- Trial name
- NCT03291184
- Testing
- peripheral neuromuscular monitor
- Where
- Belgium
- Volunteers
- 93 people
- Sponsor
- Onze Lieve Vrouw Hospital
Neuromuscular Blockade
Neuromuscular Blockade Improves Surgical Conditions
This study is designed to test the clinical hypothesis that a neuromuscular block improves surgical conditions, operation time, and post-operative pain.
- Trial name
- NISCO (NCT00895778)
- Testing
- Neuromuscular blockade with rocuronium and reversal with sugammadex
- Where
- Germany
- Volunteers
- 57 people
- Sponsor
- Technical University of Munich
Complex Regional Pain Syndromes, Postherpetic Neuralgia
The Comparison of Sympathetic Blockade of Stellate Ganglion Block and Thoracic Paravertebral Block
The purpose of this study is to investigate the effect of ultrasound-guided thoracic paravertebral block (TPVB) when performing sympathetic block for upper limb pain control.
- Conditions
- Complex Regional Pain Syndromes, Postherpetic Neuralgia, Phantom Limb Pain, Chronic Post Surgical Pain
- Trial name
- NCT04876989
- Testing
- US-SGB, US-TPVB
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University
Amyloidosis Cardiac, Aortic Stenosis, Severe
Analysis of Calcium Score of Severe Aortic Stenosis in Patients With and Without Cardiac Amyloidosis (CAUSATIVE Study)
The concomitant presence of cardiac amyloidosis (CA) in patients with aortic stenosis (AS) may challenge the estimation of stenosis degree.
- Trial name
- CAUSATIVE (NCT06066632)
- Where
- Italy
- Volunteers
- 480 people
- Sponsor
- University Hospital of Ferrara
Acute Pain, Chronic Pain
ERECTOR SPINE PLANE BLOCK VERSUS LOCAL INFILTRATION ANAESTHESIA FOR TRANSFORAMINAL PERCUTANEOUS ENDOSCOPIC DISCECTOMY
The main aim of our study was to test the hypothesis that Erector spine plane block (ESP) with sedation will provide the similar employment of fentanyl and propofol during surgery as an infiltrative local anaesthesia with…
- Conditions
- Acute Pain, Chronic Pain, Postoperative Pain, Anesthesia
- Trial name
- NCT05483647
- Testing
- Local infiltrative anaesthesia, Erector spine plane block
- Where
- Ukraine
- Volunteers
- 52 people
- Sponsor
- Lviv National Medical University
Postoperative Complications, Postoperative Pain
Suprainguinal Fascia Iliaca Block Versus PENG Block for Hip Arthroplasty Analgesia
In recent years, suprainguinal fascia iliaca block (SFIB) has emerged as a reliable analgesic option for primary total hip arthroplasty (THA).
- Conditions
- Postoperative Complications, Postoperative Pain, Weakness, Muscle, Motor Activity
- Trial name
- NCT04402450
- Testing
- Ultrasound-guided suprainguinal fascia iliaca nerve block, Ultrasound-guided pericapsular nerves group of the hip block
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- University of Chile