Clinical trials: Neuromuscular Block
Neuromuscular Blockade
The Precision and Arm-to-Arm Variation of Mechanomyography and Acceleromyography for Monitoring of Neuromuscular Block
The purpose of the study is the examine the precision of acceleromyography and mechanomyography during recovery from a neuromuscular blocking agent and to examine whether there is any difference in monitoring block at the…
- Trial name
- NCT00472121
- Testing
- TOF-Watch SX (neuromuscular monitor)
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Residual Neuromuscular Blockade, Residual Paralysis, Post-Anesthesia
Incidence of Postoperative Residual Neuromuscular Blockade in Portugal
This is an epidemiological multicenter, observational, prospective study, designed to determine the incidence of postoperative residual neuromuscular blockade - defined by a TOF (train-of-four) ratio < 0.9 - at PACU arrival.
- Conditions
- Residual Neuromuscular Blockade, Residual Paralysis, Post-Anesthesia, Observational Study, Complication of Anesthesia
- Trial name
- NCT03417804
- Where
- 10 sites in Portugal
- Volunteers
- 366 people
- Sponsor
- Centro Hospitalar do Porto
Bladder Tumor
Current Intensity for the Obturator Nerve Block
The purpose of the present study was to find out the difference in current intensity required for nerve stimulation according to the presence or absence of neuromuscular blockade during the obturator nerve block procedure for…
- Trial name
- Current_ONB (NCT05872451)
- Testing
- Rocuronium Bromide, Nerve stimulator
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Chosun University Hospital
Bladder Outlet Obstruction, Multiple Sclerosis
GentleCath™ for Men Intermittent Catheter With FeelClean™ Technology
Male self catherterisng observational study.
- Conditions
- Bladder Outlet Obstruction, Multiple Sclerosis, Cauda Equina Syndrome, Enlarged Prostate With Lower Urinary Tract Symptoms
- Trial name
- NCT05470751
- Testing
- Intermittent self-catheterisation
- Where
- 16 sites in United States, France and 1 more
- Volunteers
- 72 people
- Sponsor
- ConvaTec Inc.
Suggamadex, Surgery for Congenital Heart Disease
Suggamadex and Fast-track Cardiac Anesthesia in a Developing Country
The purpose of this study is to retrospectively review our preliminary experience during a surgical trip to Tuxtla, Mexico, using suggamadex to reverse neuromuscular blockade following CPB and cardiac surgery for repair of CHD in…
- Trial name
- NCT02704351
- Testing
- Surgery
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Joseph D. Tobias
Airway Management, Supraglottic Airway Device Insertion
Effect of Neuromuscular Blocking Agent Use on Video Laryngeal Mask Airway Insertion
This study aims to investigate whether the administration of a neuromuscular blocking agent (rocuronium) improves the anatomical positioning of a third-generation video laryngeal mask airway (video LMA) in adult patients…
- Conditions
- Airway Management, Supraglottic Airway Device Insertion, Laryngeal Mask Airways, Anesthesia, General
- Trial name
- NCT07894029
- Testing
- Rocuronium, Standard Anesthesia Induction (Propofol and Remifentanil)
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Hacettepe University
Postoperative Neuromuscular Block, Postoperative Complications
Residual Neuromuscular Block in the Post-Anesthetic Unit and Postoperative Complications
The use of neuromuscular blockers (NMB) is essential to optimize surgical conditions, ensure patient immobility during the intervention and prevent complications derived from involuntary movements.
- Trial name
- Porcerito (NCT06386354)
- Testing
- Train-of-four
- Where
- 2 sites in Spain
- Volunteers
- 296 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Blood Coagulation Tests ( INR, APTT)
Sugammadex Reversal of Neuromuscular Blockade and Postoperative Bleeding
Sugammadex is new drug that is used for reversal of rocuronium induced muscle relaxation. benefits of reversal of neuromuscular blockade appears to be of great value in living donor liver transplant recipients.
- Trial name
- Suga_bleeding (NCT02939430)
- Testing
- Sugammadex intravenous, Intravenous neostigmine and atropine
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Neuromuscular Blockade
Comparing Reversal With Neostigmine and Sugammadex in Paediatric
A reversal agent is commonly given to improve neuromuscular function after intra-operative administration of non-depolarizing neuromuscular blocking agents.
- Trial name
- JS (NCT03137290)
- Testing
- Neostigmine, Sugammadex Sodium
- Where
- Malaysia
- Volunteers
- 80 people
- Sponsor
- Universiti Sains Malaysia
Muscle Weakness, Muscle Damage
Acute Physiological Responses to Twice Daily Blood Flow Restriction Training
The Academic Department of Military Rehabilitation (ADMR) is currently conducting a pan-defence, randomised control trial (RCT) investigating the utility of twice daily blood flow restriction training in UK military personnel…
- Trial name
- NCT06334224
- Testing
- Low load resistance training with blood flow restriction, Low load resistance training
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Defence Medical Rehabilitation Centre, UK
Duchenne Muscular Dystrophy, Cardiomyopathy
Nebivolol for the Prevention of Left Ventricular Systolic Dysfunction in Patients With Duchenne Muscular Dystrophy
The objective is to determine whether nebivolol, a beta-blockade drug, can prevent the development of heart disease in patients with Duchenne muscular dystrophy aged 10 to 15 year-old.
- Conditions
- Duchenne Muscular Dystrophy, Cardiomyopathy, Heart Failure
- Trial name
- NEBIDYS (NCT01648634)
- Testing
- Nebivolol
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thoracic Outlet Syndrome
PECS II Block in Thoracic Outlet Decompression
Rationale: Postoperative pain management after transaxillary thoracic outlet decompression surgery (TATOD) is difficult. In a retrospective case-control trial, we found evidence that a PECS II block is able to reduce pain and…
- Trial name
- BLOCKTOS (NCT04471545)
- Testing
- Pectoral nerve block type II
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Post-Herpetic Neuralgia
Comparison Between the Efficacy of Ultrasound-guided Erector Spinae Plane Block and Conventional Treatment for Pain Management in Patients With Post-herpetic Neuralgia
The present study aims to evaluate the efficacy of ultrasound-guided erector spinae plane block with steroids to relieve pain in cases of post-herpetic neuralgia, patient satisfaction, and record any complications post-injection.
- Trial name
- NCT07256145
- Testing
- erector spinae plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Thoracic Epidural Analgesia, Gastric Cancer
General Anesthesia and General Anesthesia Combined With Thoracic Epidural Anesthesia
This randomized controlled trial investigated whether adding thoracic epidural analgesia to general anesthesia affects intraoperative neuromuscular blockade and opioid requirements in patients undergoing gastric cancer surgery.
- Trial name
- NCT05907811
- Testing
- Neuromuscular blocker usage
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Neuromuscular Block
Adductor Canal Block In Anterior Cruciate Ligament (ACL) Repair
Adductor canal block will provide adequate analgesia to patients undergoing arthroscopic ACL reconstruction surgery, yet result in less motor blockade than a femoral block.
- Trial name
- NCT01791036
- Testing
- Adductor Canal Block, Femoral Nerve Block
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Neuromuscular Block
Dexmetomidine Intrathecally and Intravenously Additionally to Spinal Anaesthesia, in Total Knee Arthroplasty
The present study is designed to evaluate and compare the efficacy of intrathecal dexmedetomidine (DEX) as an adjuvant to Levobupivacaine in spinal anaesthesia and DEX's intravenous administration, without loading dose…
- Trial name
- NCT02966249
- Testing
- Levobupivacaine, Dexmetomidine intravenously, Normal Saline added intrathecally
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- KAT General Hospital
Activity, Motor
Periodization and Parkinson's Disease
This study will compare the effects of high-speed power resistance training to periodized training, which includes cycle of hypertrophy, strength and power, on measures of muscle strength and power and tests of daily performance…
- Trial name
- NCT07141849
- Testing
- Power Resistance Training, Periodized Resistance Training
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Miami
Obstructive Sleep Apnea, Hypertonia, Muscle
Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia
The researchers are investigating if the Self-Supporting Nasopharyngeal Airway (ssNPA) device can be used in the treatment of obstructive sleep apnea in children with Hypotonic Upper Airway Obstruction (HUAO).
- Conditions
- Obstructive Sleep Apnea, Hypertonia, Muscle, Nasal Airway Obstruction, Tolerance
- Trial name
- NCT05527652
- Testing
- Self-Supporting Nasopharyngeal Airway (ssNPA)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Pain, Acute, Pain, Chronic
Ketamine With Multilevel Paravertebral Block for Post Video-assisted Thoracic Surgery Pain
Postoperative pain after thoracic surgery is associated with adverse outcomes. The current strategy to prevent postoperative pain is the use of regional anesthesia and analgesic agents.
- Conditions
- Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- NCT03280017
- Testing
- Ketamine, Normal saline
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Mahidol University
General Anesthesia, Breast Disease
Neuromuscular Block in Laryngeal Mask Airway(LMA) Insertion
The aim of this study is to evaluate the success rate, insertion time and complication depending on the use of neuromuscular blocking agent when inserting the laryngeal mask airway (LMA).
- Trial name
- NCT01035021
- Testing
- use of rocuronium when the LMA is inserted
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Seoul National University Bundang Hospital