Clinical trials: Neuromuscular Block
Migraine in Children, Pain, Neuropathic
Transnasal Sphenopalatine Ganglia Block for Management of Chronic Migraines in Pediatric Patients
Single-center, open-label, pre-post treatment pilot study to evaluate the safety and effectiveness of sphenopalatine ganglia blocks for the treatment of chronic migraine in the pediatric population.
- Trial name
- NCT04466826
- Testing
- Headache Journal, Sphenopalatine Block, Tx360
- Where
- United States
- Sponsor
- Washington University School of Medicine
Cubital Tunnel Syndrome, Biceps Tendon Rupture
Infraclavicular or Supraclavicular Brachial Plexus Blocks for Elbow Surgery
This study compares the infraclavicular approach to supraclavicular approach of brachial plexus block for elbow surgery.
- Trial name
- NCT02677506
- Testing
- Supraclavicular, Infraclavicular
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Neuromuscular Blockade
Deep vs Moderate Block: Impact on Operating Conditions & Patient Satisfaction
This study compares surgeon's satisfaction of operating conditions and patient's satisfaction following laparoscopic gynecological surgeries in two groups of patients, half of whom will receive deep neuromuscular blockade and the…
- Trial name
- NCT02794714
- Testing
- Deep neuromuscular blockade, Moderate neuromuscular blockade
- Sponsor
- Kuala Lumpur General Hospital
Complication of Ventilation Therapy, Observation of Neuromuscular Block
Influence of the Neuromuscular Blockade on Mask Ventilation
Mask ventilation during induction of anesthesia can be improved by administration of neuromuscular blocking agents (NMBAs). NMBAs are usually administered after testing mask ventilation; however, muscle relaxants may improve mask…
- Trial name
- NCT02318810
- Testing
- Rocuronium 0.3 mg/kg, Rocuronium 0.6 mg/kg, Rocuronium 0.9 mg/kg
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- University of Rostock
Cholecystectomy, Laparoscopic
Neuromuscular Block and Anesthetic Depth Monitoring
The purpose of this study is to evaluated whether the depth of neuromuscular block may affect the unicon value of anesthetic depth monitoring system (ADMS).
- Trial name
- NCT02575443
- Testing
- Rocuronium (MB group), Rocuronium (DB group)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Bundang Hospital
Neuromuscular Blockade Monitoring, NMT
NMT EasyFit Sensor and Cable
The purpose of this clinical study is to collect and assess feedback from clinical users regarding the functionality and device use and collection of raw parameter date from the NMT Sensor and NMT Cable.
- Trial name
- NCT07394140
- Testing
- Collection of NMT Technology
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- GE Healthcare
Carpal Tunnel Syndrome (CTS)
Combined Stellate Ganglion Block With Median Nerve Hydrodissection Versus Median Nerve Hydrodissection Only in Carpal Tunnel Syndrome
the study aims to compare clinical and electrophysiological outcomes of combined stellate ganglion block plus median nerve hydrodissection versus hydrodissection alone in carpal tunnel syndrome, assessing pain, function…
- Trial name
- NCT07839611
- Testing
- combined stellate ganglion block procedure and median nerve hydrodissection, Ultrasound-Guided Median Nerve Hydrodissection Procedure only
- Volunteers
- 80 people
- Sponsor
- Fayoum University
Neuralgia,Postherpetic
The Effect of Epidural Steroid Use in Patients With Continous Epidural Block in PHN Patients.
The efficiency of epidural steroid injection in patients who has postherpetic neuralgia is well known. In this study, the purpose is whether the continous epidural steroid injection is effective or not.
- Trial name
- NCT03995563
- Testing
- Dexamethasone, Ropivacaine
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Korea University Guro Hospital
Minimally Invasive Cardiac Surgery
Postoperative Respiratory Complications According to Neuromuscular Block Reversal After MICS
Postoperative respiratory complications according to the type of drug (sugammadex, pyridostigmine) used for reversible neuromuscular block when extubating an endotracheal tube in the operating room after minimally invasive…
- Trial name
- NCT04957836
- Testing
- reversal with sugammadex
- Where
- South Korea
- Volunteers
- 1,216 people
- Sponsor
- Pusan National University Yangsan Hospital
Nephrostomy; Complications, Pneumoperitoneum
A Trial Comparing Deep Versus Moderate Neuromuscular Block - in Low Pressure Pneumoperitoneum
Live kidney transplantation is first choice for patients with end-stage kidney disease. Therefore, the safety and well-being of kidneys donors are highly important objectives in live kidney donation.
- Conditions
- Nephrostomy; Complications, Pneumoperitoneum, Observation of Neuromuscular Block
- Trial name
- LEOPARD-3 (NCT02602964)
- Testing
- Deep neuromsucular block
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Radboud University Medical Center
Colorectal Cancer
Study to Evaluate Oxygen Monitoring at Different Stages of Neuromuscular Blockade in Colorectal Surgery
Anesthesia favouring deep/intense neuromuscular blockade during laparoscopy may restore hemodynamics. However, no studies has been performed comparing oxygenation parameters during laparoscopy in colorectal surgery in either…
- Trial name
- OXYMUBLOC (NCT02327494)
- Testing
- neuromuscular blockade
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Hospital Universitari de Bellvitge
Postoperative Neuromuscular Block
Sugammadex and Heart Failure
Although anticholinesterase reversal agents have been used in combination with anticholinergic drugs for over half a century, it has been suggested that they should be used with caution in patients with underlying cardiovascular…
- Trial name
- NCT01509651
- Testing
- Sugammadex
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Onze Lieve Vrouw Hospital
Bowel Dysfunction, Postoperative Complications
Sugammadex To IMprove Bowel Function
Colon and rectal surgery is associated with high cost, long length of stay, high postoperative surgical site infection rate, high incidence of postoperative nausea and vomiting, and a high rate of hospital readmission.
- Conditions
- Bowel Dysfunction, Postoperative Complications, Neuromuscular Blockade
- Trial name
- STIM_Bowel (NCT04546672)
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Oregon Health and Science University
Morbid Obesity
Sugammadex Dosage Based on Ideal Body Weight for Profound Rocuronium-induced Neuromuscular Blockade Reversal in Morbidly Obese Patients
This randomized double blind clinical trial focuses on patients with Body Masse Index ≥ 40 kg/m2, undergoing scheduled surgery. Neuromuscular transmission monitoring at the adductor is performed using.
- Trial name
- NCT02545595
- Testing
- Sugammadex 1 mg/kg, Sugammadex 2 mg/kg, Sugammadex 4 mg/kg
- Where
- France
- Sponsor
- Poitiers University Hospital
Cancer of Bladder
Comparison of Obturator Nerve Blockade and Neuromuscular Blockade
Patients diagnosed with posterolateral bladder tumors will be invited to participate in the study. Subjects will be randomized to receive an ultrasound-guided obturator block or a neuromuscular blocking agent after the induction…
- Trial name
- NCT03063255
- Testing
- Obturator block, Neuromuscular block
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Florida
Neuromuscular Blockade
Pharmacokinetics of Rocuronium for Deep Block (DeepRocu)
Rocuronium is a non-depolarising neuromuscular blocking agent. The compound has a rapid onset and an intermediate duration of action.
- Trial name
- DeepRocu (NCT03545308)
- Testing
- Rocuronium
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Change in Serum Levels of the Estimated Inflammatory Cytokines, Total Dose of IO Fentanyl
Deep Versus Moderate Neuromuscular Blocking
This study aimed for Determination of the impacts of deep neuromuscular blockade (DNMB) on surgical outcomes, consumption of perioperative opioid analgesia, and serum levels of inflammatory cytokines in comparison to moderate NMB…
- Conditions
- Change in Serum Levels of the Estimated Inflammatory Cytokines, Total Dose of IO Fentanyl, PO Morphine, Surgeons' Rating
- Trial name
- NCT07485517
- Testing
- Moderate Neuromuscular Blockade, Deep neuromuscular block
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Menoufia University
Spondylolisthesis, Lumbar Disc Herniation
Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery
Rationale: Lumbar spine surgery is associated with high postoperative pain scores and analgesic use, despite use of multimodal analgesia.
- Conditions
- Spondylolisthesis, Lumbar Disc Herniation, Lumbar Spinal Stenosis, Lumbar Disc Disease
- Trial name
- RCT-ESPB (NCT05345249)
- Testing
- Ropivacaine Hydrochloride Injection, Sodium chloride
- Where
- Netherlands
- Volunteers
- 76 people
- Sponsor
- Ilse van de Wijgert
Electromyography, Neuromuscular Monitoring
Neurostimulation and Electromyographs Assessment of th TetraGraph in Healthy (Volunteers
TetraGraph is a newly developed EMG-based (electromyograph), quantitative, battery-powered neuromuscular monitoring system intended for daily clinical use.
- Trial name
- NEAT-2 (NCT02630576)
- Testing
- Neuromuscular stimulation
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Debrecen
Residual Neuromuscular Block
Neostigmine Reversal And Neuromuscular Recovery
Patients undergoing surgery often receive paralytic agents (or neuromuscular blocking agents (NMBAs)) to facilitate the procedure. At the end of surgery, the effects NMBAs are reversed with a drug called neostigmine.
- Trial name
- NCT02433808
- Testing
- Neostigmine Group, No Neostigmine group
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Endeavor Health