Clinical trials: Neuromuscular Disease Patients
Post COVID Syndrome, Chronic Fatigue Symptoms
Energy Level Diary for Patients With Post-COVID Syndrome
Post-COVID-19 Syndrome (PCS) is characterized by symptoms, including fatigue, reduced physical performance, dyspnea, cognitive impairment, and psychological distress.
- Trial name
- NCT06883500
- Testing
- Energy diary
- Where
- 2 sites in Germany
- Volunteers
- 66 people
- Sponsor
- University of Witten/Herdecke
Sarcopenia, Hip Fractures
Sarcopenia and Bone Mineral Density Relation in Hip Fracture Patients
The study aims to investigate the relationship between sarcopenia and bone mineral density (BMD) in patients with hip fractures using sonographic thigh adjustment ratio (STAR) and dual-energy X-ray absorptiometry (DXA), as well…
- Trial name
- NCT06508957
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Kastamonu University
Intensive Care Unit (ICU) Acquired Weakness (ICU - AW), Acquired Brain Injury (Including Stroke)
Functional Electrical Stimulation to Treat Critical Neuromyopathy After Severe Stroke: a Pilot Study.
This study aims to evaluate the effectiveness of physiotherapy treatment combined with functional electrical stimulation (FES) in a small group of patients with severe acquired brain injury (SABI) of vascular origin and with a…
- Trial name
- RISE (NCT07130929)
- Testing
- Functional Electrical Stimulation, Conventional physiotherapy
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Diabetic Neuropathies
Randomized Study of Intravenous Immunoglobulin (IVIg) in Patients With Subacute Proximal Diabetic Neuropathy
OBJECTIVES: I. Determine the effect of intravenous immunoglobulin on recovery time of patients with proximal diabetic neuropathy. II. Determine whether rate of response is dose dependent in these patients.
- Trial name
- NCT00004407
- Testing
- immune globulin
- Volunteers
- 75 people
- Sponsor
- Mayo Clinic
Fibromyalgia, Primary
Obstructive Sleep Apnea Syndrome and Fibromiyalgia
-------------Obstructive sleep apnea syndrome (OSAS) is a syndrome characterized by recurrent complete (apnea) or partial (hypopnea) upper respiratory tract obstruction episodes during sleep and a decrease in blood oxygen…
- Trial name
- NCT06595771
- Testing
- continuous positive airway pressure, Polysomnography
- Where
- Turkey (Türkiye)
- Volunteers
- 225 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Sarcopenia, Postoperative Complications
Sarcopenia in Colorectal Cancer Patients, Intervention Study
The sarcopenia is a new concept for evaluating the functional status of patients, introduced during the last 20 years. This is defined as the relationship between the deterioration of muscle mass and the decrease in strength, the…
- Conditions
- Sarcopenia, Postoperative Complications, Infection;Post Surg Procedure
- Trial name
- NCT05491434
- Testing
- Protein supplement
- Where
- Spain
- Volunteers
- 370 people
- Sponsor
- Hospital Universitari de Bellvitge
Critically Ill
Testing of a New Therapeutic Vibration Device to Reduce Neuromuscular Weakness in Hospitalized Patients (Hospital Testing)
Objective: Test the ability of vibration to produce physiologic, biochemical, and anatomic changes consistent with exercise that would help prevent the development of muscle weakness that occurs when patients are immobile for…
- Trial name
- NCT05352100
- Testing
- Therapeutic Vibration Device
- Where
- United States
- Sponsor
- University of Michigan
Adhesive Capsulitis, Shoulder Pain
Proprioceptive Neuromuscular Facilitation Techniques in Patients With Adhesive Capsulitis
Adhesive capsulitis is a condition that causes limitation of function and movement in the shoulder joint and affects many activities of daily life.
- Conditions
- Adhesive Capsulitis, Shoulder Pain, Shoulder Frozen
- Trial name
- NCT04878848
- Testing
- Proprioceptive Neuromuscular Facilitation Exercises, Conventional Rehabilitation Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
Amyotrophic Lateral Sclerosis
Pharyngeal Electrical Stimulation in Amyotrophic Lateral Sclerosis
During the course of ALS most patients develop swallowing deficits. In this pilot study we investigate if dysphagia in ALS can be improved by Pharyngeal Electrical Stimulation (PES).
- Trial name
- NCT03481348
- Testing
- Pharyngeal Electrical Stimulation
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Ulm
Myasthenia Gravis
Subcutaneous Immunoglobulin for Myasthenia Gravis
This is a prospective open-label, randomized, parallel arm clinical trial. The primary objective of the study is to evaluate the safety and efficacy of Cuvitru 20% subcutaneous immunoglobulin in patients with myasthenia gravis…
- Trial name
- MG_SCIG (NCT04728425)
- Testing
- subcutaneous immunoglobulin (SCIG), intravenous immunoglobulin + subcutaneous immunoglobulin (SCIG)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Fibromyalgia
Efficacy of Extremely Low Magnetic Field (ELF) in Fibromyalgic Patients
This is a randomized double-blind crossover study. The investigators applied ELF with a device named "LIMFA Therapy®" to 48 fibromyalgic patients, assigned in two groups (true-sham and sham-true).
- Trial name
- NCT03503760
- Testing
- LIMFA Therapy®
- Volunteers
- 48 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Guillain-Barre Syndrome
Evaluating Efgartigimod in Patients With Guillain-Barré Syndrome
The goal of this clinical trial is to evaluate the safety and effectiveness of Efgartigimod in patients with Guillain-Barre syndrome (GBS).
- Trial name
- NCT05701189
- Testing
- Efgartigimod Alfa-Fcab, Intravenous Immunoglobulin (IVIg)
- Where
- United States
- Sponsor
- Chafic Karam
Peripheral Neuropathy
The Role of Glutamine for Preventing Oxaliplatin-Induced Peripheral Neuropathy
Oxaliplatin is a chemotherapeutic agent, which is generally used in treatment of colorectal cancer. The dose limiting side effect of oxaliplatin is neurotoxicity.
- Trial name
- GELUPO (NCT02024191)
- Testing
- Glutamine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara Education and Research Hospital
Giant Axonal Neuropathy (GAN)
Intraneural Administration of scAAV9/JeT-GAN Into the Vagus Nerve for Patients With Giant Axonal Neuropathy (GAN)
Giant axonal neuropathy (GAN) is a rare pediatric disorder caused by autosomal recessive mutations in the GAN gene. GAN is a multisystem, neurodegenerative disorder affecting the peripheral nervous system (PNS), central nervous…
- Trial name
- NCT07543991
- Testing
- scAAV9/JeT-GAN
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Texas Southwestern Medical Center
Covid19, Muscle Atrophy
Electrical Stimulation for Critically Ill Covid-19 Patients
Unfortunately, hospital-acquired weakness is highly prevalent among COVID-19 hospitalized patients, who often require prolonged bed-rest or paralytics for an extended period of time in order to maintain oxygenation.
- Conditions
- Covid19, Muscle Atrophy, Muscle Weakness
- Trial name
- Phase I (NCT04685213)
- Testing
- Electrical Stimulation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Baylor College of Medicine
Pudendal Neuralgia, Canal Syndrome
Therapeutic Effects Analysis of Pudendal Nerve Infiltrations After 3 Months, in Patients Suffering of Pudendal Neuralgia
Pudendal neuralgia is a recent identified pathology, extremely invalidating, related to chronic pelvic entrapment. Nowadays, pudendal neuralgia can be treated with: neuropathic pains treatment specific kinesitherapy Alcock's…
- Trial name
- INFILTHERA (NCT00851513)
- Testing
- Lidocaine, Depmedrol, physiological serum
- Where
- 9 sites in France
- Volunteers
- 202 people
- Sponsor
- Nantes University Hospital
Colorectal Cancer, Peripheral Neuropathy
Rood's Approach and Oxaliplatin-induced Peripheral Neuropathy in Colorectal Cancer Patients
Oxaliplatin-induced chronic peripheral neuropathy is of major concern to oncologists and patients as it has been shown to affect patients' health-related quality of life.
- Trial name
- NCT05882396
- Testing
- Rood's approach, Traditional physical therapy program
- Volunteers
- 60 people
- Sponsor
- Cairo University
Acute Inflammatory Demyelinating Polyradiculoneuropathy, Myasthenia Gravis
Perception and Multisensory Integration in Neurological Patients Using fMRI
The main objective of the study is to explore and map brain areas involved in sensory perception and multisensory integration in patients with central or peripheral neurological damage.
- Conditions
- Acute Inflammatory Demyelinating Polyradiculoneuropathy, Myasthenia Gravis, Stroke, Anosognosia
- Trial name
- NCT01469858
- Testing
- Siemens magnetom avanto1.5 Tesla, Siemens magnetom trio A Tim system 3 Tesla
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Pseudobulbar Affect (PBA)
Safety and Efficacy of AVP-923 in PBA Patients With ALS or MS
Objectives of the study are to evaluate the safety, tolerability, and efficacy of two different doses of AVP-923 (capsules containing either 30 mg of dextromethorphan hydrobromide and 10 mg of quinidine sulfate [AVP-923-30] or 20…
- Trial name
- STAR (NCT00573443)
- Testing
- dextromethorphan hydrobromide 20 mg and quinidine sulfate 10 mg, dextromethorphan hydrobromide 30 mg and quinidine sulfate 10 mg
- Where
- 62 sites in United States, Argentina and 1 more
- Volunteers
- 326 people
- Sponsor
- Avanir Pharmaceuticals
Amyotrophic Lateral Sclerosis
An Open-Label Extension for the Phase 2 Study in Early Symptomatic Amyotrophic Lateral Sclerosis Patients on Stable Background Therapy to Assess Bioenergetic Catalysis With CNM-Au8 to Slow Disease Progression in ALS
This is an optional open-label extension to participants that have completed the clinical trial CNMAu8.205.
- Trial name
- NCT05299658
- Testing
- CNMAu8
- Where
- 2 sites in Australia
- Volunteers
- 40 people
- Sponsor
- Clene Nanomedicine
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