Clinical trials: Neuromuscular Disease Patients
POEMS Syndrome
The Treatment of Lenalidomide in Patients With POEMS Syndrome
Lenalidomide is a immunomodulatory drug derived from thalidomide, without neurotoxicity. Lenalidomide blocks the increased secretion of interleukin-6, tumor necrosis factor alpha and vascular endothelial growth factor (VEGF).
- Trial name
- NCT00971685
- Testing
- Lenalidomide and dexamethasone
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Istituto Clinico Humanitas
Congenital Myopathy
Aerobic Training in Patients With Congenital Myopathies
Congenital myopathies are clinical and genetic heterogeneous disorders characterized by skeletal muscle weakness. Most patients experience muscle weakness and fatigue throughout their life.
- Trial name
- NCT02020187
- Testing
- Exercise on a cycle-ergometer
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cervical Stenosis, Myelopathy
Assessing Microbiome in Primary Anterior Cervical Fusion Patients
Patients who are about to undergo cervical fusion surgery at Hospital for Special Surgery (HSS) are being asked to take part in this research study.
- Conditions
- Cervical Stenosis, Myelopathy, Cervical Spondylosis With Myelopathy, Degenerative Disc Disease
- Trial name
- NCT07877766
- Testing
- Primary Anterior Cervical Discectomy Procedures
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Hospital for Special Surgery, New York
Chemotherapeutic Toxicity
The Effect of Home-Based Walking Program on Peripheral Neuropathy, Fatigue and Quality of Life
The study aims to evaluate the effect of home-based walking program on peripheral neuropathy, fatigue and quality of life in patients receiving taxane and platinum-based chemotherapy.
- Trial name
- NCT06012253
- Testing
- Home Based Walking Program
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Akdeniz University Hospital
Disc Herniation, Cervical Radiculopathy
Mobilization With Movement vs. Neural Mobilization on Nerve Root Function in Patients With Cervical Radiculopathy
This study will be conducted to compare the effect of sustained natural apophyseal glides (SNAGS) versus neural mobilization on clinical outcomes such as 1- nerve root function in the form of: (A) peak to peak amplitude; (B)…
- Conditions
- Disc Herniation, Cervical Radiculopathy, Cervical Radiculopathy at C5 Nerve Root, Cervical Radiculopathy at C6 Nerve Root
- Trial name
- NCT05803954
- Testing
- Sustained natural apophyseal glides (SNAGS), Neural mobilization, Traditional physical therapy
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Fibromyalgia
Evaluating Mindfulness-Based Interventions With New Fibromyalgia Patients
The purpose of this study is to study the feasibility of a wearable brain sensing wellness device to provide mindfulness training to fibromyalgia patients who have failed medical therapy.
- Trial name
- NCT04720053
- Testing
- Wearable brain sensing wellness device headband system
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Mayo Clinic
Myasthenia Gravis, Generalized
Ravulizumab Treatment Outcomes in Patients With Generalized Myasthenia Gravis
The Polish multicentre observational (non-interventional) study aiming to collect data on the management and clinical outcomes of patients with gMG that received ravulizumab.
- Trial name
- MG-ARCADIA (NCT06909253)
- Testing
- Ravulizumab
- Where
- 11 sites in Poland
- Volunteers
- 50 people
- Sponsor
- AstraZeneca
Fibromyalgia
Eligibility Screening for National Institute of Dental and Craniofacial Research Studies
This screening protocol is designed to evaluate patients for participation in clinical studies in the Gene Therapy and Therapeutics Branch (GTTB) of the National Institute of Dental and Craniofacial Research.
- Trial name
- NCT00001983
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Neuropathic Pain
A Feasibility Study to Investigate the Dynamic Brain Imaging in Patients Following SCS- DRG
Targeted SCS is a standard and safe interventional pain procedure that is offered to patients with intractable neuropathic pain for their symptomatic relief.
- Trial name
- NCT04508127
- Testing
- Spinal cord stimulation
- Volunteers
- 10 people
- Sponsor
- Barts & The London NHS Trust
Diabetic Neuropathy
A Randomized Double-Blind Study Testing the Effects of Pregabalin on Diabetic Neuropathy
This study is designed to examine how pregabalin affects parameters of autonomic nerve regulation in correlation with change in pain, anxiety, and depressive symptoms in patients with diabetic neuropathy.
- Trial name
- Pregabalin (NCT00573261)
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Exercise Addiction, Diabetic Neuropathies
Effects of Aerobic Thai Dance in Patient With Diabetic Peripheral Neuropathy
The goal of this type of study is clinical trial. This to learn about effects of applied aerobic Thai dance exercise on gait balance and sudomotor function in patient with diabetic peripheral neuropathy.
- Trial name
- NCT06061237
- Testing
- Aerobic Thai dance exercise
- Where
- Thailand
- Volunteers
- 44 people
- Sponsor
- Chulalongkorn University
Myotonic Disorders
Prospective, Long Term, Observational Study (Patient Registry) of Paediatric Myotonic Disorders
This is a prospective, open-label, multi-centre, single arm, registry study to collect standard relevant clinical and epidemiological data during routine medical evaluation and treatment in paediatric patients with myotonic…
- Trial name
- NCT07154654
- Testing
- Mexiletine
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Lupin Ltd.
Muscular Atrophy
Relation Between Bioelectrical Impedance Analysis (BIA) and CT-scan Analysis in the ICU
Aim of the present study is to determine whether muscle mass as assessed by bioelectrical impedance analysis correlates with and corresponds to muscle mass as assessed by CT scan analysis in critically patients admitted to the…
- Trial name
- ICUBIACT (NCT02555670)
- Testing
- BIA
- Volunteers
- 222 people
- Sponsor
- Amsterdam UMC, location VUmc
Sarcopenia, Osteoporosis
Efficacy of Structured Exercise-Nutritional Intervention on Sarcopenia in Patients With Osteoporosis
This is a prospective parallel group, double-blinded randomized controlled trial. Subjects are randomized into two groups - the intervention group and waitlist control group.
- Trial name
- NCT06287502
- Testing
- β-hydroxy β-methylbutyrate (HMB), Resistance, aerobic, flexibility and balance exercise training
- Where
- Hong Kong
- Volunteers
- 13 people
- Sponsor
- Kowloon Hospital, Hong Kong
Diabetic Neuropathies
Omega-3 Fatty Acid Lipidomics in Diabetes Peripheral Neuropathy
Diabetic peripheral neuropathy (DPN) is the most common chronic complication of diabetes, affecting about 50% of patients with diabetes and leading to severe morbidity, poor quality of life, high mortality, and high health care…
- Trial name
- NCT05169060
- Testing
- Fish Oil Concentrate, 1000 Mg Oral Capsule, Salsalate Oral Tablet
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Iowa
Critical Illness, Muscle Weakness
Progressive Mobility Program and Technology to Improve the Level of Physical Activity and Functionality of ICU Patients
The purpose of this study is to verify if a protocol of early and progressive mobility which includes the use of technology is able to increase the level of physical activity and improve functionality and respiratory and muscular…
- Trial name
- NCT02889146
- Testing
- Conventional Physical Therapy, Early and progressive mobilization program, Respiratory therapy
- Where
- Brazil
- Volunteers
- 98 people
- Sponsor
- University of Sao Paulo General Hospital
Fibromyalgia
Effectiveness of Multicomponent Treatment for Fibromyalgia (FIBROWALK)
The main objective of this study is to analyse the effectiveness of the FIBROWALK multicomponent treatment program as coadjuvant of treatment-as-usual (TAU) compared to TAU alone.
- Trial name
- FIBROWALK (NCT04284566)
- Testing
- TAU + multicomponent treatment FIBROWALK, Treatment as Usual (TAU)
- Where
- Spain
- Volunteers
- 272 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Pain, Neuropathic
Ultrasonographic Insulin Versus Dexamethasone Injection With Local Anestheticss in Diabetic Patients With Mild to Moderate Median Nerve Entrapement Neuropathy .
Insulin injection in carpal tunnel compared with dexamethsone in diabetic patients
- Trial name
- NCT04781751
- Testing
- insulin injection
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
Stroke, Fatigue Syndrome, Chronic
Caregiver Burden and Psychological Outcomes in Caregivers of Stroke Patients With Lower Urinary Tract Symptoms
This cross-sectional observational study aims to evaluate caregiver burden, fatigue, sleep quality, and depression among family caregivers of stroke patients with lower urinary tract symptoms (LUTS).
- Conditions
- Stroke, Fatigue Syndrome, Chronic, Caregiver
- Trial name
- CARE-LUTS (NCT07480642)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Spastic Cerebral Palsy
Short Term Follow-up of a Botulinum Toxin Intervention in Children With Spastic Cerebral Palsy
This study investigates the effect of integrated Botulinum Neurotoxin A (BoNT) treatment on morphologic muscle and tendon properties, spasticity, joint stiffness, joint range of motion, muscle strength, gait and gross motor…
- Trial name
- NCT05126693
- Testing
- Botulinum Toxin treatment combined with a post-BoNT intensive physical therapy period guided by individualized treatment goals.
- Where
- Belgium
- Volunteers
- 61 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
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