Clinical trials: Neuromuscular Disease Patients
Sarcopenia
Clinical Study of TJ0113 Capsule in the Treatment of Patients With Sarcopenia
This study is a randomized, double-blind, multicenter, placebo parallel-controlled Phase II clinical study designed to evaluate the clinical efficacy and safety of TJ0113 Capsule in patients with sarcopenia.
- Trial name
- NCT07620938
- Testing
- TJ0113
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Hangzhou PhecdaMed Co., Ltd.
Myasthenia Gravis
Can Interval Walking Influence on Fatigue in the Danish Cohort of Myasthenia Gravis Patients
The study is a controlled, randomized intervention trial. Patients are randomized into either an intervention group or a control group. The duration of the study is 10 weeks.
- Trial name
- NCT03900585
- Testing
- Interval walking
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Peripheral Neuropathy
Evaluation of an Exercise Intervention for Vincristine Induced Peripheral Neuropathy in Pediatric Cancer Patients
The purpose of this study is to better understand whether or not children with ALL can complete an exercise program during treatment and whether or not that program may impact peripheral neuropathy.
- Trial name
- Exercise (NCT03430674)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Indiana University
Piriformis Syndrome
Effects of Fascial Distortion Model With and Without Neuromuscular Inhibition in Patients With Piriformis Syndrome
The aim of study will be to find the effects of fascial distortion model (FDM) with and without the Integrated neuromuscular inhibition technique (INIT) in piriformis syndrome.
- Trial name
- NCT05404607
- Testing
- Fascial distortion method with neuromuscular inhibition technique, Fascial distortion method
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Carpal Tunnel Syndrome
Studying Finger-thumb Grip in Patients With Carpal Tunnel Syndrome
INTRODUCTION Carpal tunnel syndrome (CTS) is a common condition that results in impaired hand function. In cases of CTS the "pinch grip" force between the thumb and index finger becomes unnecessarily high to prevent objects from…
- Trial name
- NCT02830828
- Testing
- Investigation of precision pinch grip control
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Thomas Edward Pidgeon
Adhesive Capsulitis
The Effect of PNF and Shoulder Stabilization Exercises on Pain, QoL and Functionality in Patient With AC
Adhesive capsulitis (AC), also known as frozen shoulder, is an insidious, painful condition of the shoulder lasting more than 3 months.
- Trial name
- NCT05797311
- Testing
- Proprioceptive Neuromuscular Facilitation (PNF), Shoulder Stabilization Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Uskudar University
Thoracic Outlet Syndrome
PECS II Block in Thoracic Outlet Decompression
Rationale: Postoperative pain management after transaxillary thoracic outlet decompression surgery (TATOD) is difficult. In a retrospective case-control trial, we found evidence that a PECS II block is able to reduce pain and…
- Trial name
- BLOCKTOS (NCT04471545)
- Testing
- Pectoral nerve block type II
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Knee Osteoarthritis, Sarcopenia
The Effects of Pulsed Electromagnetic Field Therapy on Patients With End-stage of Knee Osteoarthritis
A double-blinded, randomizepd controlled trial to investigate the treatment effects of pulsed electromagnetic field (PEMF) on end stage of knee osteoarthritis patients with sarcopenia will be carried out.
- Trial name
- NCT05550428
- Testing
- home-based-exercise, active pulsed electromagnetic field（PEMF）therapy
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Chemotherapy Induced Peripheral Neuropathy (CIPN), Cancer
Effect of GMI With and Without NM on LE in Cancer Patients With CIPN
The goal of this interventional study is to learn if graded motor imagery with or without added neural mobilization can treat chemotherapy induced nerve related symptoms in lower limbs of cancer patients.
- Trial name
- CIPN (NCT07712302)
- Testing
- Graded Motor Imagery, Neural Mobilization
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- University of Faisalabad
Duchenne Muscular Dystrophy, Becker Muscular Dystrophy
Ramipril Versus Carvedilol in Duchenne and Becker Patients
Data on preventive therapy in Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) affected individuals without cardiac involvement are very limited and currently lacking regard both ACE-inhibitors and…
- Trial name
- NCT00819845
- Testing
- carvedilol, ramipril
- Where
- Italy
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Catholic University, Italy
Duchenne Muscular Dystrophy (DMD)
Safety and Dystrophin Expression of SPOT-03 in Duchenne Muscular Dystrophy (DMD) Patients
The primary objective of this study is to evaluate the safety and tolerability of SPOT-03 administered by intravenous (IV) infusion to DMD patients.
- Trial name
- NCT07188012
- Testing
- SPOT-03
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Shanghai Siponuoyin Biotechnology Co Ltd
Phantom Limb Pain
Effects of Repetitive Transcranial Magnetic Stimulation in the Treatment of Phantom Limb Pain in Landmine Victims: ANTARES
Phantom Limb Pain (PLP) is a neuropathic chronic syndrome, characterized by a painful sensation in a body part that has been amputated.
- Trial name
- ANTARES (NCT01872481)
- Testing
- rTMS
- Where
- Colombia
- Volunteers
- 54 people
- Sponsor
- Fundación Cardiovascular de Colombia
Spinal Muscle Atrophy
A Study of Risdiplam in Participants With Type I and Type II Spinal Muscle Atrophy (SMA)
This multicenter, non-interventional, prospective study with a retrospective component aims to evaluate the real-world clinical outcomes, safety profile, and motor function improvements of Risdiplam treatment in participants with…
- Trial name
- NCT07531719
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Hoffmann-La Roche
Muscular Dystrophy, Duchenne
A Study to Compare Safety and Efficacy of High Doses of Eteplirsen in Participants With Duchenne Muscular Dystrophy (DMD) (MIS51ON)
Part 1 (dose escalation) will evaluate the safety and tolerability of 2 doses (100 milligrams/kilogram [mg/kg] and 200 mg/kg) of eteplirsen in approximately 10 participants with DMD; Part 2 (dose finding and dose comparison) will…
- Trial name
- MIS51ON (NCT03992430)
- Testing
- Eteplirsen
- Where
- 59 sites in United States, Colombia and 24 more
- Volunteers
- 160 people
- Sponsor
- Sarepta Therapeutics, Inc.
Dermatomyositis
Study on Lymphocyte Subsets of Peripheral Blood in Patients With Nonmyopathic Dermatomyositis Complicated With Pulmonary Interstitial Disease
To detect the changes of lymphocyte subsets in peripheral blood of non-myopathic dermatomyositis with pulmonary interstitial disease, classical dermatomyositis with pulmonary interstitial disease, rheumatism with non-inflammatory…
- Trial name
- NCT06149039
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Yanfeng Hou
Sarcopenia, Obesity
Relationship Between Glycemic Control and Irisin in Type 2 Diabetic Patients With Sarcopenic or Non-sarcopenic Obesity
The goal of this observational study is to compare glycemic control and irisin levels in subjects with diabetes mellitus type 2 with sarcopenic obesity vs non-sarcopenic obesity.
- Conditions
- Sarcopenia, Obesity, Diabetes Mellitus, Type 2
- Trial name
- NCT05908812
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Spinal and Bulbar Muscular Atrophy (SBMA), Motor Neuron Disease
Study of Hepatic Function in Patients With Spinal and Bulbar Muscular Atrophy
Background: Spinal and bulbar muscular atrophy (SBMA) is an inherited disease. It causes weakness in muscles used for swallowing, breathing, and speaking. SBMA mainly affects men, but women can carry the gene for it.
- Trial name
- NCT02124057
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
SMA II, Cerebral Palsy
Paracetamol Study in Patients With Low Muscle Mass
To investigate the safety and toxicity related to paracetamol treatment in children and adults with respectively SMA and CP.
- Trial name
- NCT03648658
- Testing
- Paracetamol 120Mg/5mL Oral Suspension
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mette Cathrine Oerngreen
Peripheral Neuropathy
The Role of Glutamine for Preventing Oxaliplatin-Induced Peripheral Neuropathy
Oxaliplatin is a chemotherapeutic agent, which is generally used in treatment of colorectal cancer. The dose limiting side effect of oxaliplatin is neurotoxicity.
- Trial name
- GELUPO (NCT02024191)
- Testing
- Glutamine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara Education and Research Hospital
Stroke, Spasticity, Muscle
FlexWave Trial: Efficacy of Extracorporeal Shock Wave Therapy in Post-Stroke Upper Limb Spasticity
Extracorporeal shock wave therapy (ESWT) has emerged as an effective therapeutic intervention for addressing post-stroke limb spasticity.
- Trial name
- NCT06365476
- Testing
- focused extracorporeal shock wave therapy (ESWT)
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
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