Clinical trials: Neuromuscular Disease Patients
Sarcopenia
HMB Supplementation and Motor Performance in Sarcopenic Patiens
Aging is often accompanied by the reduction and weakening of muscle mass, a condition defined as sarcopenia. According to the most recent criteria from the European Working Group on Sarcopenia in Older People, sarcopenia is…
- Trial name
- HMB-SARC (NCT06801808)
- Testing
- Myosave
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Femoroacetabular Impingement Syndrome
The Effect of Sacroiliac and Lumbar Mobilizations Applied in Addition to Conventional Physical Therapy
Femoroacetabular impingement (FAI) is defined as impingement caused by abnormal morphology between the femoral head-neck junction and the acetabulum in the hip joint (Aoyama et al., 2017).
- Trial name
- NCT07285876
- Testing
- Lumbosacral Mobilization, Conventional physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Fenerbahce University
Hemiplegic Shoulder Pain
Bobath Approach On Hemiplegic Shoulder Pain
In this study, it is investigated that whether Bobath approach is superior to conventional physiotherapy in terms of improving hemiplegic shoulder pain, spasticity and upper extremity functionality in stroke patients.
- Trial name
- BAHSP (NCT04768140)
- Testing
- Bobath treatment approach, Conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Arel University
Amyotrophic Lateral Sclerosis
Autologous Bone Marrow Mesenchymal Stem Cells in the Treatment of Patients With Amyotrophic Lateral Sclerosis
The goal of this study is to investigate the safety and tolerability of autologous bone marrow-derived mesenchymal stem cells administration in the individuals with diagnosed amyotrophic lateral sclerosis.
- Trial name
- UwmBmmscALS (NCT02881489)
- Testing
- Biological: Cell-based therapy
- Volunteers
- 30 people
- Sponsor
- University of Warmia and Mazury
Nerve Pain
A Study To Assess The Ability Of A Crossover Study Design To Detect The Efficacy Of Pregabalin In Post-Traumatic Neuropathic Pain Patients
The purpose of this study is to assess whether a cross-over type study design in post-traumatic neuropathic patients can be used to assess the activity of potential analgesic agents
- Trial name
- NCT00654940
- Testing
- Pregabalin (Lyrica)
- Where
- 5 sites in Canada, Sweden
- Volunteers
- 25 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Amyotrophic Lateral Sclerosis
Open-label Clinical Trial of Lacosamide in ALS
Lacosamide is administered for patients with amyotrophic lateral sclerosis (ALS).
- Trial name
- NCT03186040
- Testing
- Lacosamide
- Where
- Japan
- Volunteers
- 7 people
- Sponsor
- Chiba University
Amyotrophic Lateral Sclerosis (ALS)
Masitinib in Combination With Riluzole for the Treatment of Patients Suffering From Amyotrophic Lateral Sclerosis (ALS)
The objective is to compare the efficacy and safety of masitinib in combination with riluzole in the treatment of patients suffering from Amyotrophic Lateral Sclerosis (ALS).
- Trial name
- NCT02588677
- Testing
- Masitinib (4.5), Riluzole, Masitinib (3.0)
- Where
- Spain
- Volunteers
- 394 people
- Sponsor
- AB Science
Hematologic Malignancy, Muscle Weakness
Effects of NMES and Exercise in Hematological Cancer
Physical activity levels of adult hematologic cancer patients are deficient. The resulting physical inactivity causes fatigue, muscle loss, and deterioration in physical performance values.
- Trial name
- NCT04755465
- Testing
- Neuromuscular Electrical Stimulation, Structured Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Acibadem University
Chronic Fatigue Syndrome
Valganciclovir (Valcyte) for Chronic Fatigue Syndrome Patients Who Have Elevated Antibody Titers Against Human Herpes Virus 6 (HHV-6)and Epstein-Barr Virus (EBV)
The purpose of this study determine whether the drug valganciclovir has a significant and real benefit on the central core of symptoms experienced by patients who have high titers to EBV and HHV-6 and are experiencing…
- Trial name
- NCT00478465
- Testing
- valganciclovir
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Diabetic Neuropathy
DLBS1033 as Adjunctive Therapy for Patients With Diabetic Neuropathy
This study will evaluate the effect of DLBS1033 as adjunctive therapy in patients with diabetic neuropathy. Diabetic neuropathy is a common complication of diabetes that can cause numbness, tingling, pain, impaired nerve…
- Trial name
- NCT07683598
- Testing
- DLBS1033
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- RS H Adam Malik
Fibromyalgia
A Study of the Efficacy and Safety of Pregabalin for the Treatment of Fibromyalgia
The purpose of this study is to evaluate the efficacy and safety of pregabalin versus placebo for the symptomatic relief of pain associated with fibromyalgia.
- Trial name
- NCT00645398
- Testing
- Pregabalin
- Where
- 102 sites in United States
- Volunteers
- 751 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Diabetic Neuropathies, Peripheral Nervous System Diseases
Effect of Physical Therapy in Improving the Health of Patients With Diabetic Peripheral Neuropathy
People with diabetes can have nerve damage in their extremities (peripheral neuropathy), and this can lead them to being less able to maintain their balance when they are standing, walking or performing complex movement tasks in…
- Trial name
- DPN-QoL (NCT02115932)
- Testing
- Strength & Balance Training
- Where
- Singapore
- Volunteers
- 143 people
- Sponsor
- National University Health System, Singapore
Amyotrophic Lateral Sclerosis
Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS
A Phase 2b/3 multicenter, randomized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy, safety and tolerability of MN-166 given to ALS participants for 12 months followed by a 6-month open-label…
- Trial name
- COMBAT-ALS (NCT04057898)
- Testing
- MN-166
- Where
- 16 sites in United States, Canada
- Volunteers
- 234 people
- Sponsor
- MediciNova
Limb Girdle Muscular Dystrophy
MRI-phenotyping of Patients With Pathogenic Anoctamin 5 Variants
A large cohort of MRI scans from patients with pathogenic variants in the anoctamin 5 gene will be collected through an international collaboration to better describe muscle involvement.
- Trial name
- ANO5 MRI (NCT05102799)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Treatment Outcome, Muscle Dystonia
Quantifying Muscle Tone in Patients With Brain Injury - a Feasibility Study
This project will determine the feasibility and validity of measuring elbow muscle flexor stiffness in a population of patients with sub-acute severe acquired brain injury using two measurement methods, the portable spasticity…
- Conditions
- Treatment Outcome, Muscle Dystonia, Spasticity, Muscle, Muscle Tightness
- Trial name
- NCT04207632
- Testing
- Botulinum toxin type A injection
- Where
- Denmark
- Volunteers
- 5 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lumbar Radiculopathy
Back School or Brain School for Patients Undergoing Surgery for Lumbar Radiculopathy?
The primary scientific objective of the study entails examining whether perioperative pain neuroscience education (PPNE or 'brain school') is more effective than classical back school in reducing pain and improving pain…
- Trial name
- B²asic (NCT02630732)
- Testing
- Brain school, Back school
- Where
- 3 sites in Belgium
- Volunteers
- 120 people
- Sponsor
- Universitair Ziekenhuis Brussel
Fibromyalgia
Impact of the Restriction of Sources of Gluten in Fibromyalgia Patients
The aim of this study is to evaluate the impact of gluten-free diets on symptoms and inflammatory markers in individuals with previous diagnosis of fibromyalgia (FM), as well as to identify the presence of non-celiac gluten…
- Trial name
- NCT03129906
- Testing
- Gluten, Rice protein
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- Federal University of Minas Gerais
Cirrhosis, Frailty
Prehab and Creatine/Whey Supplementation in Frailty Among Patients With Cirrhosis
Frailty and muscle health are important for patients with chronic liver disease. This study looks at the use of a digital prehabilitation app (HEAL-ME) plus creatine and whey protein combination supplementation on maintaining…
- Conditions
- Cirrhosis, Frailty, Sarcopenia
- Trial name
- NCT07029243
- Testing
- HEAL-ME digital app, Creatine supplementation, Whey protein supplementation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Muscular Atrophy, Spinal
A Study to Collect Blood Samples From Patients With Spinal Muscular Atrophy for Biomarker Analysis
In this single center study blood samples for biomarker analysis will be collected from patients with spinal muscular atrophy. Up to 21 mL blood will be drawn from eligible patients at a single visit.
- Trial name
- NCT01910168
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Hoffmann-La Roche
Fibromyalgia, Covid-19 Fear
The Effects of Covid-19 Pandemic on The Patients With Fibromyalgia
The investigators planned to analyze the effect of Covid-19 fear and anxiety on the daily life, sleep quality and depression-anxiety levels of fibromyalgia patients.
- Conditions
- Fibromyalgia, Covid-19 Fear, Covid-19 Anxiety, Daily Life
- Trial name
- NCT04686578
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
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