Clinical trials: Neuromuscular Disease Patients
Heart Failure
Effects of Neuromuscular Electrostimulation in Patients With Acute Heart Failure
The investigators evaluated the effects of neuromuscular electrical stimulation (NMES) therapy on functional capacity and oxidative stress in patients hospitalized for an episode of acute heart failure (AHF).
- Trial name
- NCT04310072
- Testing
- Neuromuscular electrical stimulation
- Where
- Romania
- Volunteers
- 30 people
- Sponsor
- Ploesteanu Rodica Lucia
Trigger Point Pain, Myofascial, Muscle Pain
Dry Needling Versus Intramuscular Stimulation in the Management of the Myofascial Trigger Points
Hypothesis The application of intramuscular electrostimulation will be more effectiveness than the dry needling in myofascial trigger points treatment.
- Conditions
- Trigger Point Pain, Myofascial, Muscle Pain, Myofascial Pain Syndrome
- Trial name
- NCT03025230
- Testing
- Dry needling and electric stimulation, Dry needling
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Alcala
Myotonic Dystrophy Type 1 and Type 2
Study to Investigate the Efficacy and Safety of Mexiletine in Patients With Myotonic Dystrophy Type 1 and Type 2
A Randomized, Double-blind, Placebo-controlled, Multi-center Study to Investigate the Efficacy and Safety of Mexiletine During 26 Weeks of Treatment in Patients with Myotonic Dystrophy Type 1 and Type 2 [The MIND Study]
- Trial name
- MIND (NCT04700046)
- Testing
- Mexiletine 167 mg
- Sponsor
- Lupin Ltd.
Respiratory Insufficiency
Partial Neuromuscular Blockade for Lung Protective Mechanical Ventilation
Controlled mechanical ventilation may lead to the development of diaphragm muscle atrophy, which is associated with weakness and adverse clinical outcome.
- Trial name
- NCT03646266
- Testing
- Rocuronium Bromide
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Amsterdam UMC, location VUmc
Fibromyalgia
Cefaly® Device in the Treatment of Patients With Fibromyalgia.
The objective of this pilot open trial was to assess the efficacy and safety of external trigeminal nerve stimulation (e-TNS) with the Cefaly® device in fibromyalgia.
- Trial name
- NCT02546362
- Testing
- Cefaly
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Cefaly Technology
Head and Neck Cancer (H&N)
Swallowing Rehabilitation Program for Head and Neck Tumor Patients
This study aims to evaluate the effect of a structured swallowing rehabilitation program on swallowing function, trismus severity, and pain among patients with head and neck tumors, using a randomized controlled trial design.
- Trial name
- SREP-HNC (NCT07795294)
- Testing
- Swallowing Rehabilitation Program
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Delta University for Science and Technology
Severe Sepsis, Respiratory Failure
Muscle Atrophy in Patients With Severe Sepsis
This study is being done to help determine whether patients with severe sepsis (overwhelming inflammation in the body as a result of an infection) lose muscle and become weak more rapidly than patients with other severe…
- Trial name
- NCT01717651
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Ohio State University
Lymphedema Arm, Lymphedema Due to Radiation
Effectiveness of a Therapeutic Exercise Program With Specific Upper Limb Exercises to Reduce Lymphedema and Neuropathy in Breast Cancer Patients: A Pre-post Study (LYNMA)
This study aims to evaluate the effectiveness of a therapeutic exercise program designed specifically for women with breast cancer.
- Conditions
- Lymphedema Arm, Lymphedema Due to Radiation, Lymphedema, Breast Cancer, Peripheral Neuropathy Due to Chemotherapy
- Trial name
- LYNMA (NCT07170631)
- Testing
- Therapeutic exercise
- Volunteers
- 30 people
- Sponsor
- Universitat Internacional de Catalunya
Adult Angiosarcoma, Adult Epithelioid Sarcoma
Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma
This phase II trial is studying how well sorafenib works in treating patients with metastatic, locally advanced, or recurrent sarcoma.
- Conditions
- Adult Angiosarcoma, Adult Epithelioid Sarcoma, Adult Leiomyosarcoma, Adult Malignant Fibrous Histiocytoma
- Trial name
- NCT00245102
- Testing
- sorafenib tosylate
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- National Cancer Institute (NCI)
Fibromyalgia
Explain Pain in Fibromyalgia Patients
Education of pain physiology is described as an educational session or sessions describing the neurobiology and neurophysiology of pain, and pain processing by the nervous system.
- Trial name
- NCT02474875
- Testing
- Educational program
- Where
- 4 sites in Spain
- Volunteers
- 88 people
- Sponsor
- Cardenal Herrera University
Sporadic, Inclusion Body
Immune Abnormalities in Sporadic Inclusion Body Myositis
This study will examine the abnormal immune response in patients with sporadic inclusion body myositis (s-IBM)-the most common inflammatory muscle disease in people over the age of 50.
- Conditions
- Sporadic, Inclusion Body, Myositis
- Trial name
- NCT00030212
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Type 2 Diabetes, Insulin Resistance
Effect of Neuromuscular Electrostimulation on Sympathetic Nerve Activity in Patients With Type 2 Diabetes (ELECTROSYMP2)
Physical activity (PA) is recommended for the treatment of subjects with type 2 diabetes to increase insulin sensitivity and improve metabolic control.
- Trial name
- ELECTROSYMP2 (NCT02171351)
- Testing
- effect of neuromuscular electrostimulation (NMES), effect of neuro electrostimulation (NES), effect of voluntary contractions (VC)
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Lumbar Spinal Stenosis, Neuropathic Pain
Neuropathic Pain in Patients With Degenerative Lumbar Stenosis
Pre- and postoperative pain in patients with degenerative stenosis requires great attention, as it can mislead the doctor about treatment tactics.
- Conditions
- Lumbar Spinal Stenosis, Neuropathic Pain, Spinal Disease
- Trial name
- NCT06407167
- Testing
- DN4 (Douleur Neuropathique 4 Questions) questionnaire
- Where
- Russia
- Volunteers
- 147 people
- Sponsor
- N.N. Priorov National Medical Research Center of Traumatology and Orthopedics
Fibromyalgia
NK-ORB Expression of Mu Receptor on Lymphocytes in Rehabilitation
Chronic pain is a serious disorder that causes physical suffering and emotional distress. NK cells are cytotoxic granular cells playing a crucial role in innate immunity.
- Trial name
- NK-ORB (NCT06458569)
- Testing
- Rehabilitation
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS San Raffaele Roma
Fibromyalgia
Psychological Wellbeing, Physical Activity, and Disability in Fibromyalgia
This study aims to investigate the association between psychological wellbeing, physical activity, and disability in patients with fibromyalgia.
- Trial name
- NCT05946356
- Testing
- no intervention - cross-sectional observational only
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ahram Canadian University
Critical Illness, Muscle Loss
Body Composition Study in Critically Ill Patients
This is a single-center prospective observational study that aimed to describe the trajectory of change in body composition among critically ill patients who were able to function independently prior to admission.
- Trial name
- NCT04262531
- Where
- Malaysia
- Volunteers
- 90 people
- Sponsor
- University of Malaya
Motor Deficits, Lumbar Discectomy
Investigation of Preoperative Factors Influencing the Outcome of Motor Deficits in Patients Undergoing Lumbar Microdiskectomy
Lumbar disc herniations may result in lower limb weakness. In such cases, there is a strong indication for surgical intervention through microdiscectomy.
- Conditions
- Motor Deficits, Lumbar Discectomy, Muscle Weakness, Paresis
- Trial name
- NCT07413302
- Where
- 3 sites in Greece
- Volunteers
- 40 people
- Sponsor
- Aristotle University Of Thessaloniki
Aging, Sarcopenia
Effect of L-arginine on Microcirculation, Myogenesis and Angiogenesis Associated With Aging, Sarcopenia and Diabetes
This study aims was evaluated the effect of L-arginine on microcirculation, vasoreactivity / endothelial function and vascular smooth muscle of young and old women with Sarcopenia or Type 2 Diabetes Mellitus measured by Nailfold…
- Conditions
- Aging, Sarcopenia, Type 2 Diabetes, Microcirculation
- Trial name
- NCT04112875
- Testing
- L-arginine, Maltodextrin
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Nutrition Aspect of Cancer, Sarcopenia
Malnutrition and Sarcopenia Screening in Chemotherapy Patients
The study will include approximately 150 adult outpatients diagnosed with solid tumors who are currently receiving chemotherapy.
- Conditions
- Nutrition Aspect of Cancer, Sarcopenia, Chemotherapeutic Agent Toxicity
- Trial name
- NCT07163286
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Çanakkale Onsekiz Mart University
Knee Osteoarthritis
Investigation of the Effect of Superimposed Neuromuscular Electrical Stimulation in Patients With Knee Osteoarthritis.
The aim of the study is to investigate the effects of superimposed neuromuscular electrical stimulation with active contraction on physical function, muscle and joint structure, functionality, and quality of life in patients with…
- Trial name
- NCT06277570
- Testing
- conventional physiotherapy, NMES, Superimposed NMES
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Gulhane School of Medicine
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