Clinical trials: Neuromuscular Disease Patients
Low Back Pain
Interventional Study of Effects on Spine Height With Two Unloading Positions
The purpose of this study is to test a physical therapy intervention for reducing pain in the low back and into the legs. With individuals over the age of 40 years, this pain may be associated to changes in back height from aging…
- Trial name
- NCT01048749
- Testing
- aquatic vertical suspension., land-based supine flexion
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Texas Tech University Health Sciences Center
Male Breast Cancer, Neurotoxicity
Heavy Metal Exposure in Predicting Peripheral Neuropathy in Patients With Stage I-III Breast Cancer Undergoing Chemotherapy
This research trial studies heavy metal exposure in predicting peripheral neuropathy in patients with stage I-III breast cancer undergoing chemotherapy.
- Conditions
- Male Breast Cancer, Neurotoxicity, Peripheral Neuropathy, Stage IA Breast Cancer
- Trial name
- NCT01982591
- Testing
- laboratory biomarker analysis, questionnaire administration
- Where
- 2 sites in United States
- Volunteers
- 115 people
- Sponsor
- Fox Chase Cancer Center
Carpal Tunnel Syndrome
The Effect of Theraworx Foam in Carpal Tunnel Syndrome
Participation will be for approximately 21 days (3 study visits,1 week apart with allowance for scheduling conflicts). A topical (or placebo) foam alone or with a splint will be used.
- Trial name
- NCT04017390
- Testing
- Theraworx Foam, Theraworx Foam and night splint
- Where
- 2 sites in United States
- Sponsor
- John Fowler
Carpal Tunnel Syndrome (CTS) in Breast Cancer Patients
Laser Acupuncture on Carpal Tunnel Syndrome .
The study will be carried out on a total number of fifty-four females with age ranged 40 - 60 years old suffering from CTS post mastectomy ,the patients will be randomly assigned into two groups equal in number (27 patients for…
- Trial name
- NCT07405008
- Testing
- LASER acupuncture technique, Traditional physical therapy
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Cairo University
Complex Regional Pain Syndromes, Postherpetic Neuralgia
The Comparison of Sympathetic Blockade of Stellate Ganglion Block and Thoracic Paravertebral Block
The purpose of this study is to investigate the effect of ultrasound-guided thoracic paravertebral block (TPVB) when performing sympathetic block for upper limb pain control.
- Conditions
- Complex Regional Pain Syndromes, Postherpetic Neuralgia, Phantom Limb Pain, Chronic Post Surgical Pain
- Trial name
- NCT04876989
- Testing
- US-SGB, US-TPVB
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University
PARKINSON DISEASE (Disorder), Rigidity
Spinal Mobility, Rigidity, and Kinesiophobia in PD and TMD
Axial rigidity and loss of spinal mobility commonly observed in Parkinson's disease (PD) lead to postural deformities and substantial reductions in trunk flexibility.
- Conditions
- PARKINSON DISEASE (Disorder), Rigidity, Temporomandibular Disorders (TMDs), Mobility
- Trial name
- NCT07850674
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Brain Injuries, Spasticity, Muscle
Focal Muscular Vibration in Patients with Severe Acquired Brain Injury
Severe acquired brain injury (sABI) is a group of disorders that cause long-term disability. Rehabilitation is essential to counteract bed immobilization, muscle failure, pain, and sensory deficits that can affect the clinical…
- Trial name
- NCT05464160
- Testing
- Focal Muscular Vibration using the EVM EVO medical device (Endomedica, Italy), Conventional Rehabilitation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Fibromyalgia, Primary, Fibromyalgia
Pain Phenotypes in Patients With Fibromyalgia Syndrome
Fibromyalgia Syndrome (FMS); is a complex syndrome characterized by many symptoms such as chronic widespread pain, fatigue and sleep disorders, cognitive dysfunctions and psychiatric disorders.
- Conditions
- Fibromyalgia, Primary, Fibromyalgia, Chronic Pain Syndrome, Pain, Neuropathic
- Trial name
- NCT05941780
- Testing
- Pain classification method
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Kutahya Health Sciences University
Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy < 18y in Norway: Genotype/Phenotype, Growth, Puberty, Bone Health and Quality of Life.
The study will give a consent based epidemiological overview of Norwegian patients with Duchenne muscular dystrophy younger than 18 years of age. Genotype of the population will be described.
- Trial name
- NCT01963897
- Where
- Norway
- Volunteers
- 73 people
- Sponsor
- Oslo University Hospital
Fibromyalgia Syndrome
Comparison of the Effects of Balance-proprioception and Aerobic Exercises on Functional Status and Strength Parameters in Patients With Fibromyalgia.
In this study, it was aimed to examine the effects of aerobic exercise and balance-proprioception exercises on pain, functionality and strength parameters of fibromyalgia patients and to compare the two exercise types.
- Trial name
- FMS (NCT04437524)
- Testing
- therapeutic exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Istanbul University
Myeloma, Lymphoma
Feasibility of an Adapted Physical Activity Program for Patients Treated With an Autograft (APA²)
Therapeutic intensification followed by an autograft of hematopoietic stem cells is a standard of care for young patients with myeloma from the first line and for lymphoma from the second or third line of treatment.
- Conditions
- Myeloma, Lymphoma, Autologous Transplant
- Trial name
- APA² (NCT04320420)
- Testing
- Adapted Physical Activity
- Where
- 2 sites in France
- Volunteers
- 57 people
- Sponsor
- Weprom
Stroke Rehabilitation, Cerebrovascular Stroke
Error Augmentation Motor Learning Training Approach in Stroke Patients
Deficits in upper limb (UL) functional recovery persist in a large proportion of stroke survivors. Understanding how to obtain the best possible UL recovery is a major scientific, clinical and patient priority.
- Conditions
- Stroke Rehabilitation, Cerebrovascular Stroke, Muscle Spasticity, Upper Extremity Paresis
- Trial name
- NCT04378946
- Testing
- Intensive physical rehabilitation type training, Robotic system for supporting and monitoring arm motion, Actigraph Activity Monitor
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- McGill University
Statin-related Muscle Pain, Muscle Aches
7 Tesla MRI Study in Patients With Statin Related Muscle Complaints
Roughly 5-10% of statin-treated patients report muscle pain, aches, weakness, cramps, stiffness, or "heaviness" - typically occurring symmetrically in the legs.
- Conditions
- Statin-related Muscle Pain, Muscle Aches, Muscle Weakness, Muscle Cramp
- Trial name
- NCT04575090
- Testing
- Simvastatin
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Critical Illness, Muscle Weakness
Diaphragm Protective Ventilation in the Intensive Care Unit
Due to an accident, pneumonia or surgery, patients can have severe shortness of breath or lung damage to such an extent that it compromises vital functions. At such times, mechanical ventilation can be lifesaving.
- Conditions
- Critical Illness, Muscle Weakness, Muscle Damage, Respiration, Artificial
- Trial name
- DiaPro (NCT03527797)
- Testing
- Titration of support level
- Where
- Netherlands
- Volunteers
- 41 people
- Sponsor
- Amsterdam UMC, location VUmc
Duchenne Muscular Dystrophy
Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53)
This is a Phase 1b/2 open-label study to evaluate the safety, tolerability, pharmacokinetic (PK), pharmacodynamic (PD), and clinical effects of intravenous (IV) WVE-N531 in patients with Duchenne muscular dystrophy (DMD).
- Trial name
- NCT04906460
- Testing
- WVE-N531
- Where
- 6 sites in United States, Jordan and 1 more
- Volunteers
- 25 people
- Sponsor
- Wave Life Sciences USA, Inc.
Chronic Stroke
Repetitive Transcranial Magnetic Stimulation Associated With Physical Therapy to Reduce Upper Limb Spasticity in Post Stroke Patients
In this study, it is being investigated if the association between high frequency repetitive transcranial magnetic stimulation associated with motor physical therapy reduces spasticity, increases upper limb motor function, and…
- Trial name
- NCT03481179
- Testing
- TMS, Physical therapy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
Complex Regional Pain Syndromes, CRPS
Effect of Delta-9-Tetrahydrocannabinol on the Prevention of Chronic Pain in Patients With Acute CRPS (ETIC-Study)
The purpose of this study is to determine whether application of low dose Delta9-Tetrahydrocannabinol can prevent the development of chronic pain in patients with acute CRPS.
- Trial name
- NCT00377468
- Testing
- Delta9-Tetrahydrocannabinol
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Carpal Tunnel Syndrome
Comparative Effect of Scaphoid, Hamate Mobilization and Neural Mobilization in Patients With Carpal Tunnel Syndrome
To rule out the effects bone mobilization and neural mobilization in Carpal Tunnel Syndrome.
- Trial name
- NCT05261880
- Testing
- Neural mobilization, Scaphoid , hamate mobilization
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Intermittent Claudication, Peripheral Vascular Diseases
Does Neuromuscular Electrical Stimulation Improve the Absolute Walking Distance in Patients With Intermittent Claudication Compared to Best Available Treatment?
Intermittent claudication (IC) is caused by a blockage in the artery of the leg, causing muscle pain. Although some evidence of the efficacy of neuromuscular electrical stimulation (NMES) in the management of patients with IC…
- Trial name
- NESIC (NCT03446027)
- Testing
- NMES
- Where
- 11 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Imperial College London
CRPS I, Causalgia
Trialing of ISS in Patients With CRPS
This is a multi-center, prospective, open-label, single-arm, observational, feasibility study. The goal of this study is to determine the feasibility of intra-spinal stimulation with optimal paresthesia coverage therapy for…
- Trial name
- NCT03954080
- Testing
- Intraspinal-optimal stim therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Millennium Pain Center
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