Clinical trials: Neuromuscular Disorder
Carpal Tunnel Syndrome
Acute Effects of Warm Whirlpool Bath Therapy on Forearm and Hand Muscle Stiffness and Pain in Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is a common entrapment neuropathy that causes pain, paresthesia and functional limitations in the hand and wrist.
- Trial name
- CTS-WB (NCT07252960)
- Testing
- Warm Whirlpool Bath Therapy, Resting Control Condition
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Erzurum Technical University
Crohn Disease, Vitamin D Deficiency
Effects of Supplementation of Vitamin D in Patients With Crohn's Disease
Thus, the aim of the current study is to assess the influence of vitamin D deficiency and, consequently, of serum calcium deficiency in the body composition, muscular activity, bone mineral density, fatigue, and exercise…
- Conditions
- Crohn Disease, Vitamin D Deficiency, Fatigue, Sarcopenia
- Trial name
- NCT02704624
- Testing
- Vitamin D
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Federal University of Juiz de Fora
POEMS Syndrome
Treatment of POEMS Syndrome With Daratumumab
This trial investigates the use of Daratumumab (DARA), an antibody directed at the human cluster of differentiation 38 (CD38) molecule, for the treatment of patients with Polyneuropathy, Organomegaly, Endocrinopathy, m Protein…
- Trial name
- NCT04396496
- Testing
- Daratumumab Injection
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Arkansas
Cervical Radiculopathy
Ultrasound-Guided Electrical Dry Needling for Chronic Cervical Radiculopathy: A Randomized Controlled Trial
This randomized controlled trial aims to investigate whether ultrasound-guided electrical dry needling with conventional physical therapy is more effective than conventional physical therapy alone in the following outcome…
- Trial name
- NCT07907562
- Testing
- Ultrasound-guided electrical dry needling, Conventional Physical Therapy
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Liberty University
Stroke
Stroke, Measurement and Rehabilitation
The main aim of the study was to investigate the effects of transcranial laser stimulation together with neuromuscular electrical stimulation (NMES) in post-stroke patients.
- Trial name
- LTNMES (NCT05497791)
- Testing
- transcranial laser stimulation associated with NMES
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Painful Diabetic Neuropathy
Multimodal Intervention for Painful Diabetic Neuropathy: NeuOst Feasibility Trial
This is the feasibility study of a single-site parallel three-armed participant-blinded controlled randomised efficacy trial of a 5-week course of the 'NeuOst treatment', compared to a designated control intervention, and to…
- Trial name
- NeuOst (NCT06423391)
- Testing
- NeuOst, Control Intervention, Usual Care
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- University College of Osteopathy
Neuropathic Pain
Clinical Management of Neuropathic Pain With Ramelteon
This proposal is to conduct a double-blinded, randomized, placebo-controlled, crossover clinical study to examine the hypothesis that ramelteon would reduce pain score and improve functional status in subjects with neuropathic…
- Trial name
- NCT00753623
- Testing
- Ramelteon
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Massachusetts General Hospital
Fibromyalgia
Inspiratory Muscle Training With Powerbreath Device in Patients With Fibromyalgia
Context/background: people affected by fibromyalgia see their own life totally disturbed after the diagnosis. This disease also courses, apart from the functional and depressing worsening, with internal damage manifested by a…
- Trial name
- NCT05362396
- Testing
- Inspiratory Muscle Training with Powerbreath IMT device.
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Francisco de Vitoria
Amyotrophic Lateral Sclerosis, Progressive Muscular Atrophy
Study of ALS Reversals 2: Genetic Analyses
The purpose of this study is to try to understand why reversals of amyotrophic lateral sclerosis (ALS) and primary muscular atrophy (PMA) take place.
- Trial name
- StAR2 (NCT03464903)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Duke University
Amyotrophic Lateral Sclerosis
Study to Investigate the Efficacy and Safety of FAB122 (Daily Oral Edaravone) in Patients With Amyotrophic Lateral Sclerosis
Multicenter, multinational, double-blind, randomized (2:1), placebo-controlled Phase III study to investigate the efficacy and safety of 100 mg FAB122 once daily as oral formulation in ALS patients.
- Trial name
- ADORE (NCT05178810)
- Testing
- FAB122
- Where
- 38 sites in Belgium, France and 9 more
- Volunteers
- 313 people
- Sponsor
- Ferrer Internacional S.A.
Muscular Dystrophies, Muscular Dystrophy
Muscle Tissue Bank for Muscular Dystrophy
This protocol proposes to establish gene expression profiles of muscular dystrophies for correct diagnosis and for development of experimental therapies for these diseases.
- Trial name
- NCT01950897
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
MELAS Syndrome, Ketogenic Dieting
Effectiveness of Ketogenic Diet in MELAS Syndrome
The goal of this clinical trial is to evaluate the effectiveness of ketogenic diet in patients with MELAS syndrome. The main questions it aims to answer are: Clarify the curative effects of ketogenic diet in the treatment of…
- Trial name
- NCT06013397
- Testing
- Ketogenic diet
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke, Spasticity, Muscle
Impact of Muscular Fatigability on Spastic Co-contractions After Stroke Patients
This study evaluates the effects of an isokinetic fatigue protocol of the quadriceps on the amount of co-contractions of this last with the hamstrings during a maximal isometric flexion movement in hemiparetic stroke patients.
- Conditions
- Stroke, Spasticity, Muscle, Muscle Fatigue, Gait, Hemiplegic
- Trial name
- COCON (NCT03342820)
- Testing
- Muscle fatigue
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
Piriformis Syndrome
Comparison of Laser and Shockwave Therapy for Piriformis Syndrome With Adjunctive Exercise
This study is a prospective randomized controlled trial comparing the effectiveness of low-level laser therapy combined with exercise versus radial extracorporeal shockwave therapy combined with exercise in patients with…
- Trial name
- LASWEX-PS (NCT07567703)
- Testing
- Low-Level Laser Therapy + Therapeutic Exercise, Radial Shockwave Therapy + Therapeutic Exercise
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Beni-Suef University
Carpal Tunnel Syndrome (CTS)
Efficacy of Corticosteroid Injection and Nerve Hydrodissection in Carpal Tunnel Syndrome
The subject of the study is to use current treatment methods in patients with nerve compression in the wrist and compare their effects.
- Trial name
- NCT06882603
- Testing
- hydrodissection, Steroid injection, Exercise
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Amyotrophic Lateral Sclerosis
Developing a Discrimination Model to Diagnose ALS
To combine several brain imaging techniques to develop a new diagnostic test to help with earlier diagnosis of amyotrophic lateral sclerosis.
- Trial name
- NCT01995903
- Testing
- MRI(magnetic resonance imaging)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Amyotrophic Lateral Sclerosis, Caregiver Burden
A Mindful Community for People With ALS and Their Primary Caregivers
The psychological impact of ALS on patients and caregivers is high, significantly affecting their quality of life (QOL). Despite this impact, there is not much research about psychological interventions that could reduce…
- Trial name
- NCT05595850
- Testing
- Mindfulness, Mindful Learning
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Harvard University
Stroke
Validation of a Spasticity Measurement Tool
The objective of this project is to investigate the validity of a handheld spasticity measurement tool against standard clinical measurements of spasticity.
- Trial name
- NCT05374174
- Testing
- Tardieu Scale for Spasticity
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Shirley Ryan AbilityLab
Muscle Wasting
Effects of Functional Electrical Stimulation in Patients Undergoing Coronary Artery Bypass Grafting Surgery
Even with major advances in clinical therapy and percutaneous interventions, coronary artery bypass grafting (CABG) is the most common cardiac surgery performed worldwide and is an effective treatment in reducing symptoms and…
- Trial name
- NCT03560713
- Testing
- Functional Electrical Stimulation (FES)
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Universidade Federal de Santa Maria
Fibromyalgia, D Vitamin Deficiency
Valuation of Efficacy and Safety of Vitamin D3 Use in 80 Women Diagnosed With Fibromyalgia. Using FIQ Score and VAS.
Fibromyalgia is a disease that significantly decreases the quality of life of people who suffer from it, has great repercussions at the socio-economic level due to the incapacity it produces.
- Trial name
- NCT03369379
- Testing
- D3 Vitamin
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
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