Clinical trials: Neuromuscular Disorder
Chronic Fatigue Syndrome
Guanidinoacetic Acid Loading for Chronic Fatigue Syndrome
Chronic fatigue syndrome (CFS) is a debilitating condition of unknown etiology. Recent studies have shown that CFS is associated with impaired cellular energetics and low levels of phosphocreatine.
- Trial name
- NCT02213679
- Testing
- Guanidinoacetic acid
- Where
- Serbia
- Volunteers
- 20 people
- Sponsor
- Center for Health Sciences, Serbia
Vitamin D Deficiency, Sarcopenia
Effect of Vitamin D3 Supplementation on Muscle Mass in ICU Patient
A randomized double blind placebo control trial study will be conducted in critically ill patients with vitamin D deficiency. Investigator aimed to study the effect of oral vitamin D3 supplementation, compare to placebo, on…
- Conditions
- Vitamin D Deficiency, Sarcopenia, Critical Illness
- Trial name
- NCT02594579
- Testing
- Vitamin D3
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Neuromuscular Diseases in Children, Cerebral Palsy, Spastic
Muscle Spasticity Reduction in Children With Cerebral Palsy by Means of Hippotherapy
The aim of this study is to evaluate if a intervention with hippotherapy will improve spasticity for children ages 3-14 who have cerebral palsy.
- Conditions
- Neuromuscular Diseases in Children, Cerebral Palsy, Spastic, Spasticity, Muscle
- Trial name
- NCT03212846
- Testing
- Hippotherapy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Cadiz
Foot Ulcer, Diabetic Foot
A Study on the Efficacy and Safety of Long-Term Treatment and Re-Treatment of Lower Extremity Diabetic Ulcers With REGRANEX
The purpose of this study is to evaluate the efficacy and safety of REGRANEX® Gel compared with placebo when applied for up to 52 consecutive weeks to recurring or non-healing ulcers of the ankle or foot related to diabetes.
- Conditions
- Foot Ulcer, Diabetic Foot, Skin Ulcer, Diabetic Neuropathies
- Trial name
- NCT00034788
- Testing
- Becaplermin
- Volunteers
- 84 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Neurofibromatosis 1
Evaluating Genetic Modifiers of Cutaneous Neurofibromas in Adults With Neurofibromatosis Type 1
The main goal of this protocol is to develop a well-phenotyped genetic biobank to identify genetic variants associated with the heterogeneous clinical presentations of Neurofibromatosis Type 1 (NF1).
- Trial name
- NCT04941027
- Where
- 2 sites in United States
- Volunteers
- 1,046 people
- Sponsor
- Stanford University
Fibromyalgia
THE EFFECT OF CHIROPRACTIC THORACIC MANIPULATION ON PAIN, DEPRESSION, SLEEP AND QUALITY OF LIFE IN PATIENTS WITH FIBROMYALGIA
This study aimed to investigate the effects of thoracic chiropractic manipulations on pain intensity, depression levels, sleep, and quality of life in women diagnosed with fibromyalgia.
- Trial name
- NCT06194942
- Testing
- chiropractic manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bahçeşehir University
Stroke, Spasticity
Early Injection of Botulinum Toxin on Motor Function and Gait Pattern in Stroke Patients
Spasticity, muscle weakness, abnormal gait pattern are co-morbidities commonly seen in stroke patients. They cause disabled condition of patients in activities of daily life and functional performance, and also accidental falls…
- Trial name
- NCT01817816
- Testing
- Botox_A, Botox_B
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Changhua Christian Hospital
Radiculopathy, Lumbosacral Region, Radiculopathy Lumbar
The Effect of High-power Laser Therapy on Pain, Functional Disability, Range of Motion and Pressure Pain Threshold in Subjects With Radicular Low Back Pain Due to Intervertebral Disc Herniation
Low back pain is the predominant cause of disability on a global scale. In the year 2015, the worldwide point prevalence of activity-limiting low back pain stood at 7·3%, suggesting that at any given moment, 540 million…
- Trial name
- NCT06151704
- Testing
- High intensity laser therapy, Motor control exercise
- Where
- Iran
- Volunteers
- 36 people
- Sponsor
- Iran University of Medical Sciences
Sacral Tarlov Cysts, Symptomatic Sacral Cysts
Long-Term Outcomes of Different Surgical Techniques for Sacral Tarlov Cysts: A Prospective Cohort Study
Brief Summary The goal of this observational study is to evaluate the long-term outcomes of different surgical techniques for sacral Tarlov cysts in adult patients aged 18-75 years diagnosed with symptomatic sacral Tarlov cysts.
- Conditions
- Sacral Tarlov Cysts, Symptomatic Sacral Cysts, Chronic Pain Related to Sacral Cysts, Neurological Dysfunction Associated With Tarlov Cysts
- Trial name
- NCT06756984
- Testing
- Partial Cyst Wall Resection with Nerve Root Sleeve Plasty, Partial Cyst Wall Resection with Nerve Root Sleeve Reinforcement and Reconstruction:, Autologous Fat/Muscle with Fibrin Glue Microscopic Cyst Filling
- Volunteers
- 150 people
- Sponsor
- Beijing Jishuitan Hospital
Closed Femur Fracture
Rehabilitation Enhanced by Partial Arterial Inflow Restrictions
The Rehabilitation Enhanced by Partial Arterial Inflow Restriction (REPAIR) Study will be conducted in a patient population of individuals recovering from a traumatic diaphyseal fracture of the femur.
- Trial name
- REPAIR (NCT02746458)
- Testing
- Blood Flow Restriction, Delfi PTSII Tourniquet System
- Where
- 8 sites in United States
- Volunteers
- 219 people
- Sponsor
- Major Extremity Trauma Research Consortium
Anesthesia
Potential Role of Intravenous Lidocaine Versus Intravenous Ketamine for Pain Management in Fibromyalgia Patients
The aim of the study is to assess the efficacy of intravenous lidocaine versus intravenous ketamine in treatment of fibromyalgia patients.
- Trial name
- NCT06184958
- Testing
- Lidocaine group, Ketamine group
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Surgical Complication, Pain, Postoperative
Anti-inflammatory Effect of Platelet-Rıch Fıbrın
This study evaluated the anti-inflammatory effect of platelet-rich fibrin (PRF) applied to the extraction socket after impacted mandibular third molar surgery with subjective and objective parameters.
- Conditions
- Surgical Complication, Pain, Postoperative, Edema Face
- Trial name
- NCT05336578
- Testing
- Platelet rich fibrin application
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Nilay Er
Fibromyalgia
Gabapentin in Fibromyalgia Trial (GIFT)
This study will assess the safety and effectiveness of the drug gabapentin in reducing pain associated with primary fibromyalgia.
- Trial name
- NCT00057278
- Testing
- gabapentin
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Haemophilus Influenzae Type b, Diphtheria
Safety of DTPa-IPV/Hib & DTPa-HBV-IPV/Hib, Followed by DTPa-IPV/Hib Vaccine in Infants Who Received Hepatitis B Vaccine
To assess the safety and reactogenicity of the DTPa-HBV-IPV/Hib vaccine and DTPa-IPV/Hib vaccine. This DTPa-IPV/Hib vaccine given at 3 and 4 months of age is co-administered with GSK Biologicals' rotavirus vaccine or Placebo.
- Conditions
- Haemophilus Influenzae Type b, Diphtheria, Tetanus, Poliomyelitis
- Trial name
- NCT00325143
- Testing
- DTPa-HBV-IPV/Hib, DTPa-IPV/Hib vaccine
- Where
- 3 sites in Singapore
- Volunteers
- 702 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Fibromyalgia, Rheumatoid Arthritis
Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated…
- Trial name
- NCT05277025
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Florida
Familial Erythromelalgia
A Phase 1b Study of BHV-7000 in Participants With Inherited Erythromelalgia
The purpose of this study is to test the potential benefits of BHV-7000 in reducing chronic pain in participants with IEM with a previously demonstrated gain of function mutation in the SCN9A gene.
- Trial name
- NCT07262268
- Testing
- BHV-7000
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Biohaven Therapeutics Ltd.
ANCA Associated Vasculitis
the Application of Diffusion Tensor Imaging in the Evaluation of Peripheral Neuropathy in ANCA Associated Vasculitis
1. Include qualified 50 ANCA-associated vasculitis(AAV) patients; and the first 27 patients will be divided into 3 groups with different diffused tension image (DTI) parameters and to choose the best strategy； 2.
- Trial name
- NCT04923074
- Testing
- diffusion tensor imaging(DTI) evaluation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Fibromyalgia
Study of Mattress Type in Fibromyalgia
The purpose of this research study is to determine if a new mattress relieves the symptoms of fibromyalgia and improves sleep, and if this is the case, whether one type of mattress is better than the other in doing so.
- Trial name
- NCT01108718
- Testing
- Tempur-Pedic Mattress (2 months), Control Mattress (2 months)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Beth Israel Medical Center
Sarcopenia, Sleep
Exercise and the Sleep for the Sarcopenic Elderly
International data indicate that approximately 10% of the elderly will be affected by sarcopenia, a multifactorial syndrome that leads to the progressive and generalized loss of mass and muscular strength, leading to a decrease…
- Conditions
- Sarcopenia, Sleep, Physical Activity
- Trial name
- ESSE (NCT03616249)
- Testing
- Sleep, Resistance Exercise
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Chronic Hypercapnic Respiratory Failure, Obesity Hypoventilation Syndrome
Patient -Ventilator Interaction in Chronic Respiratory Failure
To evaluate a novel advanced physiological monitoring system to improve nocturnal non-invasive ventilation (NIV) in Neuromuscular disease (NMD), Chest wall disease (CWD), Chronic Obstructive Pulmonary Disease (COPD) and Obesity…
- Conditions
- Chronic Hypercapnic Respiratory Failure, Obesity Hypoventilation Syndrome, Neuromuscular Disease, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT01371149
- Testing
- Surface parasternal electromyography (EMG) set up
- Where
- 2 sites in United Kingdom
- Volunteers
- 58 people
- Sponsor
- Michelle Ramsay
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.