Clinical trials: Neuromuscular Disorder
Fibromyalgia
Effectiveness of VIRTUAL FIBROWALK STUDY
The main objective of this study is to analyse the effectiveness of the VIRTUAL FIBROWALK multicomponent treatment program as coadjuvant of treatment-as-usual (TAU) compared to TAU alone.
- Trial name
- NCT04571528
- Testing
- TAU + multicomponent treatment VIRTUAL FIBROWALK, Treatment as Usual (TAU), TAU + Physiotherapy part of VIRTUAL FIBROWALK
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Mechanical Ventilation Complication, Neuromuscular Electrical Stimulation
NMES to Prevent Respiratory Muscle Atrophy in Mechanically Ventilated Patients
Patients requiring prolonged time on the ventilator are susceptible to a wide range of clinical complications and excess mortality. It is therefore imperative for them to wean at the earliest possible time.
- Conditions
- Mechanical Ventilation Complication, Neuromuscular Electrical Stimulation, Muscle Weakness
- Trial name
- NCT03453944
- Testing
- VentFree prototype (VF03-K) active stimulation
- Where
- 3 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- University Medical Center Nijmegen
Fatigue, Fatigue Syndrome, Chronic
Psychological Treatment for Persistent Fatigue
This is a non-randomized pilot study to investigate the feasibility and acceptability of a transdiagnostic psychological intervention for primary care patients in Region Stockholm, Sweden, who suffer from persistent and disabling…
- Conditions
- Fatigue, Fatigue Syndrome, Chronic, Exhaustion; Syndrome
- Trial name
- NCT06341751
- Testing
- Psychological treatment for persistent fatigue
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Karolinska Institutet
Amyotrophic Lateral Sclerosis
Investigation on Home Care Needs of ALS Patients and Their Caregivers
The research target 1. To investigate the home nursing knowledge needs of ALS patients; 2. Investigate the needs of ALS caregivers for home nursing knowledge; 3.
- Trial name
- NCT04950231
- Testing
- The questionnaire survey
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking University Third Hospital
Ankle Inversion Sprain, Chronic Instability of Joint
Effectiveness of Balance Training and Dynamic Neuromuscular Stabilization Training in Amateur Athletes with Chronic Ankle Instability
The goal of this clinical trial is to determine and compare the effects of balance and dynamic neuromuscular stabilization training on ankle function ability, functional instability severity, physical activity level, muscle…
- Conditions
- Ankle Inversion Sprain, Chronic Instability of Joint, Chronic Pain, Athlete Foot
- Trial name
- NCT06296537
- Testing
- Dynamic Neuromuscular Stabilization Training (DNS), Balance Training, Conventional Training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Medipol University
Incomplete Spinal Cord Injury, Transverse Myelitis
Ultrasound Imaging Based Sensing of Human Ankle Motion Intent and Control Strategies for Ankle Assistance
Robotic therapies aim to improve limb function in individuals with neurological injury. Modulation of robotic assistance in many of these therapies is achieved by measuring the extant volitional strength of limb muscles.
- Trial name
- NCT05249595
- Testing
- Surface electromypgraphy-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Surface electromypgraphy and ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Carpal Tunnel Syndrome, Median Nerve Entrapment
An Absorbable Suture Versus a Non-absorbable Suture in Carpal Tunnel Release, a Randomized Controlled Trial
The study compares two widely used treatments in closing the wound after open carpal tunnel release surgery: absorbable and non-absorbable sutures.
- Trial name
- SUPER (NCT05503719)
- Testing
- Surgical wound closed with an absorbable suture, Surgical wound closed with a non-absorbable suture
- Where
- Finland
- Volunteers
- 116 people
- Sponsor
- Kuopio University Hospital
Myasthenia Gravis
Tacrolimus Combined With Low-dose Prednisone for Treatment of Myasthenia Gravis
This study is designed to evaluate the effectiveness and safety of tacrolimus combined with low-dose prednisone in the management of myasthenia gravis patients, compared to tacrolimus as initial immune monotherapy.
- Trial name
- NCT04768465
- Testing
- Pyridostigmine, Prednisone, Tacrolimus, Pyridostigmine, Tacrolimus
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Da, Yuwei, M.D.
Spasticity, Muscle, Stroke
Multimodal Instrumented Assessment of Post-stroke Elbow
The proposed clinical trial will employ the NEUROExos Elbow Module (NEEM), an active robotic exoskeleton, for the passive mobilization and active training of elbow flexion and extension in 60 sub-acute and chronic stroke patients…
- Conditions
- Spasticity, Muscle, Stroke, Upper Limb
- Trial name
- NCT04484571
- Testing
- Neuroexsos elbow module
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Azienda USL Toscana Nord Ovest
Cerebellopontine Angle Tumor
Compare the Operating Condition of Two Levels of Muscle Relaxation on Facial Nerve MEP Monitoring in CPA Surgery
compare the operating condition of two different levels of muscle relaxation on facial nerve monitoring using transcranial motor evocked potential in CPA surgery .
- Trial name
- NCT04148534
- Testing
- Rocroniom, Non Depolarizing Muscle Relaxant
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Muhammad Magdy Gaber
Duchenne Muscular Dystrophy (DMD)
Factors Influencing Physical Activity Levels in Children With Duchenne Muscular Dystrophy: An ICF-CY-Based Study
Duchenne Muscular Dystrophy (DMD) is a neuromuscular disease characterized not only by progressive muscle weakness but also by cognitive, behavioral, and psychosocial impairments.
- Trial name
- NCT07369609
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Fibromyalgia (FM), Chronic Fatigue Syndrome (CFS)
Functional and Affective Effects of a Brief tDCS Intervention in Fibromyalgia and Chronic Fatigue Syndrome
Functional and Affective Effects of a brief tDCS Intervention in Fibromyalgia and Chronic Fatigue Syndrome Fibromyalgia (FM) and chronic fatigue syndrome (CFS) are characterized by persistent, multidimensional symptoms arising…
- Trial name
- FibFatDCS (NCT07573709)
- Testing
- Transcraneal Direct Current Electric Stimulation (tDCS), Transcranial Direct Current Electric Stimulation (tDCS)
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Donostia
Carpal Tunnel Syndrome
Corticosteroid Injection Effectiveness in Carpel Tunnel Patients With Negative or Mild EMG Studies
Carpal Tunnel Syndrome (CTS) is the most common nerve entrapment syndrome worldwide. There are currently no studies examining the effectiveness of corticosteroid injections in patients with normal (negative) EMG studies.
- Trial name
- NCT04737239
- Testing
- Corticosteroid injections for CTS treatment
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Henry Ford Health System
Fibromyalgia
Trazodone and Its Augmentation With Pregabalin in the Treatment of Fibromyalgia
The study has a double purpose: a first phase intends to assess the effectiveness and tolerability of trazodone, an antidepressant with sedative and sleep-promoting properties, in the treatment of fibromyalgia; a second phase…
- Trial name
- NCT00791739
- Testing
- trazodone, pregabalin
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Universidad de Granada
Lumbar Radiculopathy, Lumbar Spinal Stenosis
The Impact of Contrast Media Used in Epidural Steroid Injections on Thyroid Function Tests
This study is aim to disclose the effect of contrast media, which used in epidural steroid injections, on the parameters of thyroid function tests (TFTs). The patients who underwent an epidural steroid injection were included.
- Conditions
- Lumbar Radiculopathy, Lumbar Spinal Stenosis, Cervical Radiculopathy, Cervical Stenosis
- Trial name
- NCT05404412
- Testing
- Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people
- Sponsor
- Marmara University
Fibromyalgia, Irritable Bowel Syndrome
Observational Study of Control Participants for the MAPP Research Network
The Control Study for the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has been established to focus on a broader approach to the study of Interstitial Cystitis (IC)/Painful Bladder…
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Fatigue Syndrome, Chronic
- Trial name
- MAPP-Control (NCT01098292)
- Where
- 8 sites in United States
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sciatica
Comparison of Intravenous Ibuprofen and Paracetamol in Patients With Sciatica Presented to the Emergency Department
Currently, Paracetamol and Ibuprofen are widely used by emergency physicians in Turkey for the pain treatments. The objective of the study was to assess whether intravenous Paracetamol has superior Sciatica pain reduction will…
- Trial name
- NCT02777320
- Testing
- paracetamol, Ibuprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Pamukkale University
Myelopathy, Compressive, Radiculopathy, Cervical
Can Prophylactic Foraminotomy Prevent C5 Palsy
C5 palsy (C5P) is a well-known, although rare complication of cervical spine decompression surgery. In severe forms, C5P causes debilitating upper extremity weakness involving the deltoids and/or biceps brachii muscles…
- Conditions
- Myelopathy, Compressive, Radiculopathy, Cervical, C5 Palsy
- Trial name
- NCT03023696
- Testing
- Bilateral Cervical Keyhole Foraminotomy, Cervical Decompression
- Where
- United States
- Volunteers
- 480 people
- Sponsor
- The Cleveland Clinic
Cisplatin Adverse Reaction, Cisplatin Nephrotoxicity
Evaluation of the Effect of N-acetylcysteine in Preventing Cisplatin-Induced Toxicities in Cancer Patients
Evaluation of the Effect of N-acetylcysteine in Preventing Cisplatin-Induced Toxicities in Cancer Patients
- Conditions
- Cisplatin Adverse Reaction, Cisplatin Nephrotoxicity, Cisplatin Induced Peripheral Neuropathy, Cancer Patients
- Trial name
- NCT06297369
- Testing
- N acetyl cysteine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Fibromyalgia Syndrome
Metformin for Fibromyalgia Symptoms (INFORM Trial)
The main purpose of the project is to evaluate the safety and efficacy of low dose metformin for improving symptoms associated with fibromyalgia syndrome (FMS) via modulating neuroinflammatory pathways.
- Trial name
- NCT05900466
- Testing
- Metformin
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Utah
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