Clinical trials: Neuromuscular Disorder
Neuropathic Pain
The Use of Transcutaneous Electrical Nerve Stimulation (TENS) for Chronic Pain of Predominantly Peripheral Neuropathic Origin
The aim of this study is to investigate the effectiveness of TENS in addition to routine care in patients with chronic pain of predominantly neuropathic origin, compared to treatment with routine care alone." Hypothesis: An…
- Trial name
- NCT00716326
- Testing
- Transcutaneous Nerve Stimulation (TENS), Cefar Primo Pro TENS device
- Where
- Norway
- Volunteers
- 115 people
- Sponsor
- Norwegian Fund for Postgraduate Training in Physiotherapy
Neuropathic Pain
Study of NMDA Antagonists and Neuropathic Pain
The aim of this study is to evaluate if memantine or dextromethorphan gave in relay to ketamine maintains or induces a decrease of pain intensity.
- Trial name
- NMDA (NCT01602185)
- Testing
- Dextromethorphan (drug used like antitussive), Memantine (drug used in Alzheimer's disease)
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Clermont-Ferrand
Sarcopenia
Effect of Home-Based Exercise Program in Older Adults With Sarcopenia
In the prospective, randomized, controlled multi-centre study, 100 patients who were clinically diagnosed with sarcopenia were assigned to either a home-based exercise group or the control group.
- Trial name
- NCT04598464
- Testing
- Home based exercise
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University
Cardiac Amyloidosis
Mitochondrial Function in Transthyretin Amyloidosis
Hereditary (familial) amyloidosis arising from the misfolding of a mutated or variant transthyretin, is the most frequent form of amyloid cardiomyopathy in the Caribbean basin.
- Trial name
- MIT-Amylose (NCT03328338)
- Where
- Martinique
- Volunteers
- 12 people
- Sponsor
- University Hospital Center of Martinique
Disc Disease
Outcome After Lumbar Epidural Steroid Injection
prospectively validate a fibronectin-aggrecan complex as a biomarker for response to ESI for radiculopathy with HNP
- Trial name
- NCT01079026
- Volunteers
- 26 people
- Sponsor
- Scuderi, Gaetano J., M.D.
Glycogen Storage Disease, GSD Type 0A
Rare Glycogen Storage Diseases Natural History Study
The purpose of this study is to collect and study key medical data about several ultra-rare GSDs (Glycogen Storage Diseases) including, but not limited to, GSD types 0a, 0b, VII, X, XII, XIII, XV, PRKAG2 syndrome and Danon…
- Conditions
- Glycogen Storage Disease, GSD Type 0A, GSD Type 0B, GSD VII
- Trial name
- NCT06795152
- Testing
- No intervention
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Duke University
Muscle Weakness
Randomized Controlled Trial Comparing Traditional Pelvic Floor Rehabilitation to Pilates in Increasing Pelvic Muscles Strength.
The objective of this randomized controlled trial is to determine whether a standardized Pilates exercise program can effectively strengthen pelvic floor muscles when compared with conventional pelvic muscle rehabilitation.
- Trial name
- NCT00549458
- Testing
- Pilates, Pelvic muscle rehabilitation therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Muscle Loss
Galactooligosaccharide and Aging
Sarcopenia is a progressive muscle disease, most commonly affecting older individuals, that is categorised by 1) low muscle strength, 2) low muscle quantity or quality, and 3) low physical performance.
- Trial name
- NCT06411964
- Testing
- Prebiotic
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Bath
Fibromyalgia, Physiotherapy
Effectiveness of the Strain Counterstrain Technique in Women With Fibromyalgia Syndrome
This study evaluates whether strain counterstrain therapy affects pain, fatigue, psychological status, and quality of life in women diagnosed with fibromyalgia.
- Conditions
- Fibromyalgia, Physiotherapy, Pain, Strain Counterstrain Technique
- Trial name
- NCT07421609
- Testing
- Conservative Physiotherapy Program, Strain Counterstrain Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Hasan Kalyoncu University
Amyloidosis Cardiac, Stenosis Coronary
Non-Interventional Study on the Prevalence of Cardiac Amyloidosis in Patients With Higher-Grade Aortic Valve Stenosis - Evaluation Using Echocardiography, Computed Tomography, Tc99-SPECT/CT and Cardiac Magnetic Resonance Imaging (CMR)
Degenerative aortic stenosis (AS) is frequently accompanied by left ventricular hypertrophy and diastolic dysfunction, features that overlap with transthyretin (ATTR) cardiac amyloidosis.
- Conditions
- Amyloidosis Cardiac, Stenosis Coronary, TAVI(Transcatheter Aortic Valve Implantation)
- Trial name
- NIS-TAVI-AMY (NCT07752732)
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- University Hospital Tuebingen
Fibromyalgia, Aromatherapy
The Effect of Peppermint Oil Aromatherapy on Pain, Functional Capacity and Cost in Fibromyalgia Patients
This study was designed to evaluate the effect of topically applied peppermint oil (Mentha × piperita) on chronic pain and functional capacity experienced by fibromyalgia patients, as well as its cost-effectiveness.
- Conditions
- Fibromyalgia, Aromatherapy, Cost
- Trial name
- NCT07326163
- Testing
- Peppermint Oil, sweet almond oil, Duloxetine
- Where
- Turkey (Türkiye)
- Volunteers
- 175 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Neuropathy (Disorder)
Contribution of an Off-the-shelf Carbon Ankle Foot Orthosis (AFO) in the Management of Walking Functional Impairment
The objective of this study is to assess the superiority in achieving personal goals (set by the patient and the medical team) according to the GAS scale (Goal Attainment Scaling) while wearing the carbon medical device Ankle…
- Trial name
- DEFISTEP (NCT05131399)
- Testing
- Phase A1, Phase B1, Phase A2
- Where
- 8 sites in France
- Volunteers
- 20 people
- Sponsor
- Thuasne
Lumbar Radiculopathy
MORE in the Management of Lumbosacral Radiculopathy Symptoms: A Randomized Controlled Trial
INTRODUCTION: Chronic low back pain (CLBP) is a ubiquitous musculoskeletal (MSK) complaint that often presents as a chronic and difficult to treat condition.
- Trial name
- MORE (NCT04818606)
- Testing
- Mindfulness Oriented Recovery Enhancement
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National University of Natural Medicine
Sarcopenia
Respiratory Sarcopenia in Older Adults
The objectives of this study are to describe the prevalence of respiratory sarcopenia, evaluate its pattern of evolution over a one-year follow-up, and determine the response to a therapeutic exercise program in older adults in a…
- Trial name
- NCT06548984
- Testing
- diaphragmatic exercises, Respiratory muscle training
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Felipe León Morillas
Amyotrophic Lateral Sclerosis
Biomarkers in Different Types of Amyotrophic Lateral Sclerosis (ALS) Patients Being Treated With Edaravone
This study is being conducted to help the investigators better understand how the new FDA approved medication Edaravone (also known as Radicava) works in subsets of patients with ALS.
- Trial name
- NCT04097158
- Testing
- Sample Collection
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Loma Linda University
Mechanical Ventilation, Expiratory Muscle
Expiratory Muscle Function in Critically Ill Ventilated Patients
Inspiratory muscle weakness develops rapidly in ventilated critically ill patients and is associated with adverse outcome, including prolonged duration of mechanical ventilation and mortality.
- Conditions
- Mechanical Ventilation, Expiratory Muscle, Critical Illness, Muscle Atrophy or Weakness
- Trial name
- EMFIC (NCT04333186)
- Testing
- Data from ultrasound measurements
- Where
- Netherlands
- Volunteers
- 113 people
- Sponsor
- Amsterdam UMC, location VUmc
Articular; Rigid
Physiotherapeutic Case Studies in Frozen Shoulder Pathology
The stiff shoulder presents symptoms such as pain, loss of mobility and strength, being more common the idiopathic origin associated to the female gender.
- Trial name
- CH-Case (NCT05175586)
- Testing
- First data analysis, Second data analysis, database
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- GEMA LEÓN BRAVO
Fibromyalgia, Chronic Fatigue Syndrome (CFS)
Effect of Physical Exercise and Neuromodulation on Pain, Sleep and Fatigue in Patients With Fibromyalgia
Fibromyalgia (FMS) is a chronic, multifactorial syndrome characterized by widespread pain, fatigue, and cognitive disturbances. This interventional study evaluates the impact of structured physical training using…
- Trial name
- NCT07242573
- Testing
- Physical Training Program, NESA X-Signal, Conventional Physiotherapy
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
Knee Osteoarthritis, Fibromyalgia
Effects of Creatine Supplementation in Women With Knee Osteoarthritis and Fibromyalgia
The purpose of this study is to determine whether creatine associated or not to exercise training can improve physical performance in patients with knee osteoarthritis and fibromyalgia.
- Trial name
- NCT00749983
- Testing
- Creatine supplementation, Dextrose supplementation
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Stroke, Peripheral Neuropathy
Arm Motor Control on Bi and Uni ADLs
This study is being performed to assess how certain chronic disabilities - stroke, upper extremity (UE) amputation, spinal cord injuries (SCI), cerebral palsy (CP) - differ from healthy subjects in their ability to perform ADLs.
- Conditions
- Stroke, Peripheral Neuropathy, Spinal Cord Injuries, Cerebral Palsy
- Trial name
- BiAs (NCT02778529)
- Testing
- Bilateral assessment robots (BiAS)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
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