Clinical trials: Neuromuscular Disorder
Poliomyelitis
A Clinical Study to Evaluate the Safety and Immunogenicity of Inactivated Poliomyelitis Vaccine in Healthy Infants
The purpose of the study is to evaluate safety and immunogenicity of inactivated poliomyelitis vaccine based on Sabin strain (LBVC) in healthy infants to select optimal dose of LBVC as well as to demonstrate the lot-to-lot…
- Trial name
- NCT03169725
- Testing
- Inactivated Poliomyelitis Vaccine (Sabin strain), Inactivated Poliomyelitis Vaccine (Salk strain)
- Where
- 3 sites in Philippines, Thailand
- Volunteers
- 1,417 people, healthy volunteers welcome
- Sponsor
- LG Chem
Duchenne Muscular Dystrophy
Open-label Extension of the HOPE-2 Trial
This Phase 2, multi-center, open-label extension trial will provide deramiocel (CAP-1002) to subjects that were enrolled in the HOPE-2 trial and completed 12 months of follow-up.
- Trial name
- HOPE-2-OLE (NCT04428476)
- Testing
- Deramiocel (CAP-1002)
- Where
- 5 sites in United States
- Volunteers
- 13 people
- Sponsor
- Capricor Inc.
Motor Neuropathy, Sensory Neuropathy
Short-term Evaluation of Motor and Sensory Function in Post-COVID-19 Patients
SARS-COV-2 infection reframed medical knowledge in many aspects, yet there is still a lot to be discovered. our aim is to evaluate neurological impact of covid-19; if there is any.
- Trial name
- NCT05721040
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Bilateral Spastic Cerebral Palsy
Kinesio Taping Versus Electrical Stimulation on Dysphagia in Bilateral Cerebral Palsy
The purpose of this study will be to compare the effect between kinesiotaping and neuromuscular electrical stimulation on dysphagia in children with bilateral spastic cerebral palsy.
- Trial name
- NCT07695350
- Testing
- Structured Oromotor Exercises, Kinesio Taping, Neuromuscular Electrical Stimulation
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Attention Deficit Disorder With Hyperactivity
Sleepiness and Driving Performances in Adults With Attention-Deficit/ Hyperactivity Disorder (ADHD)
The Attention Deficit/ Hyperactivity Disorder (ADHD) is a developmental disorder which affects 3 to 5 % of school age children. This disorder persists in the adulthood for 60 % of subjects.
- Trial name
- SOMTDA/H (NCT01160874)
- Testing
- Polysomnography, Maintenance Wakefulness Test, Neuropsychological evaluation
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Stroke, Acute
Efficacy of Adhesive Strength of New Hydrogel Formulation
The study will look at the stickiness of a new skin adhesive incorporated into a new next generation geko™ device called the geko™ X-T3 and compare it to the adhesive currently used into the geko™ T3 device.
- Trial name
- NCT04309110
- Testing
- or geko™ X-T3
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Firstkind Ltd
Myasthenia Gravis
Clinical Prognosis and Progression of Myasthenia Gravis Patients
This study collects the clinical data of myasthenia gravis (MG) patients, assesses outcomes and adverse effects of different treatment regimens, and searches for risk factors of conversion to generalized MG.
- Trial name
- NCT04101578
- Testing
- Symptomatic Treatment, Steroids, Immunosuppressive Agents, Plasma Exchange(PE), Intravenous Immunoglobulin(IVIg)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Da, Yuwei, M.D.
Guillain Barre Syndrome
Intravenous Immunoglobulin (IVIG) Versus Plasma Exchange (PE) for Ventilated Children With Guillain Barre Syndrome (GBS)
Comparing whether intravenous immune globulin or plasma exchange is superior in treating mechanically ventilated children with Guillain Barre syndrome.
- Trial name
- NCT01306578
- Testing
- IVIG, Plasma Exchange
- Where
- Egypt
- Volunteers
- 41 people
- Sponsor
- Mansoura University Children Hospital
Duchenne Muscular Dystrophy (DMD)
Nutritional Status and Therapy in DMD Patients
Brief Summary The goal of this clinical trial is to evaluate the impact of a disease-specific, individualized diet on the nutritional status and functional abilities of Duchenne muscular dystrophy (DMD) patients.
- Trial name
- NCT06682585
- Testing
- Individualised dietary intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 9 people
- Sponsor
- Ankara University
Cerebral Palsy, Spasticity
Lateral Cord Stimulation as a New Treatment for Refractory Spastic Cerebral Palsy
The aim of our work is to investigate whether electrical Lateral Cord Stimulation (LCS) causes an inhibitory and modulatory action by indirect cerebellar activation, so releasing spasticity and the spastic syndrome in selected…
- Trial name
- Andreani1 (NCT02199015)
- Testing
- Lateral spinal cord surgical implant of electrodes
- Where
- 2 sites in Argentina, Germany
- Volunteers
- 40 people
- Sponsor
- Juan Carlos M. Andreani MD
Muscle Weakness
A Study in Older Participants Who Have Fallen and Have Muscle Weakness
LY2495655 is an investigational drug being tested for muscle wasting.
- Trial name
- NCT01604408
- Testing
- LY2495655
- Where
- 22 sites in United States, Argentina and 4 more
- Volunteers
- 201 people
- Sponsor
- Eli Lilly and Company
Amyotrophic Lateral Sclerosis (ALS)
Identification of Early Markers for ALS
Although several molecules have been proposed as biomarker candidates, a clinically established signature for an early or even premotor diagnosis of ALS is not available.
- Trial name
- PremodiALS (NCT07213440)
- Testing
- lumbar puncture
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Limbs Arthrosis, Non Arthrosic Limbs Arthralgia
Association of Transcutaneous Electrical Nerve Stimulation and Hypnosis
At Saint-Antoine's hospital, in CETD a multidisciplinary team takes care of patients with chronic pain. Free-drug techniques are available to reduce their consumption of analgesics.
- Conditions
- Limbs Arthrosis, Non Arthrosic Limbs Arthralgia, Chronic Lomboradiculalgia, Chronic Back Pain
- Trial name
- HYPTENS (NCT01944150)
- Testing
- Transcutaneous electrical nerve stimulation, Transcutaneous electrical nerve stimulation and hypnosis
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fibromyalgia
Effect Of Neuromodulation In Patient With Fibromyalgia Syndrome
This study was designed to examine the efficacy of Neuromodulation therapy By using transcutanous electric nerve stimulation( TENS) in Patients With FMS and to provide preliminary evidence regarding its effects on pain ,anxiety…
- Trial name
- NCT06799091
- Testing
- Low frequency TENS
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Neck Disease, Head and Neck Cancer, Neuropathic Pain
"Effect of Low Level Laser Therapy on Neuropathic Pain After Neck Dissection Surgery''
The purpose of the study was to evaluate the effect of Low Level Laser Therapy on neuropathic pain after neck dissection surgery.
- Trial name
- NCT06762574
- Testing
- Low Level Laser Therapy
- Volunteers
- 52 people
- Sponsor
- Cairo University
Anxiety, Depression
Effect of Homeopathy, Acupuncture or Anthroposophic Medicine in Women's Quality of Life
Patients will be randomly assigned to two separate groups. Both patient groups will be evaluated using the WHOQOL-BREF questionaire.
- Conditions
- Anxiety, Depression, Premenstrual Tension, Hot Flashes
- Trial name
- NCT02504515
- Testing
- World Health Organization Quality of Life Bref Questionnaire
- Where
- Brazil
- Volunteers
- 906 people
- Sponsor
- Federal University of Minas Gerais
Pain, Neuropathy;Peripheral
Morphological and Metabolic Changes of Dorsal Root Ganglion and Sympathetic Ganglion in Patients With Postherpetic Neuralgia on MRI
Object: Postherpetic neuralgia (PHN) is pain that persists for 1-3 months after herpes zoster onset. It is the most common complication of herpes zoster and occurs in 15-40% of patients with herpes zoster.
- Trial name
- NCT04880408
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Huazhong University of Science and Technology
Motor Neuron Disease, Respiratory Failure
Tolerability, Safety and Efficacy of Sigh Breaths During NIMV in Motor Neuron Disease
Non-invasive mechanical ventilation (NIMV) is the recommended standard of care as initial therapy for patients with motor neuron disease (MND) with deterioration of the respiratory function.
- Conditions
- Motor Neuron Disease, Respiratory Failure, Amyotrophic Lateral Sclerosis
- Trial name
- NCT04240925
- Testing
- NIMV with sigh breaths, Standard NIMV
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Ospedale San Raffaele
Neuropathic Pain
Adrenocorticotropic Axis and Neuropathic Pain
Chronic pain is often associated with a chronic stress and HHSG axis plays a pivotal role in maintaining homeostasis. The literature reports that pain in patients treated with opioids, significant changes are taking place in this…
- Trial name
- HORMONES (NCT01543425)
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Fibromyalgia
Home-Based Exercise Program for Fibromyalgia
This study aims to evaluate the effects of a home-based exercise program on patients with fibromyalgia. Participants will be randomly assigned to either an exercise group or a control group.
- Trial name
- FIBRO-EX (NCT07200050)
- Testing
- Home-based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kutahya Health Sciences University
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