Clinical trials: Neuromuscular Exercise
Osteoarthritis, Knee
Descriptive Study of Strength Training Exercises to Activate the Muscles of the Operated Leg After Total Knee Replacement
Background: In the early phase after a total knee replacement (TKA), patients experience multi-level weakness in the operated leg, which is caused primarily by reduced central (CNS) activation failure of the muscles - especially…
- Trial name
- NCT01708980
- Testing
- Six different strength training exercises
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Exercise
The Effects of β-Hydroxy-β-methylbutyrate Free Acid and High-Intensity Interval Training
Objectives: 1) Determine the effect of 4-weeks of high intensity interval training (HIIT) and free acid form β-Hydroxy-β-methylbutyrate (HMB-FA) on VO2peak, lactate threshold, critical power, anaerobic working capacity and…
- Trial name
- NCT01941368
- Testing
- HMB-FA, High Intensity Interval Training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Metabolic Technologies Inc.
Mitochondrial Diseases, Mitochondrial Myopathy
Exercise Training Effects on Muscle Function in Adults With Mitochondrial Myopathy
The goal of this observational study is to learn how exercise training affects molecular processes in skeletal muscle in adults with mitochondrial myopathy, compared with healthy adults.
- Trial name
- MM-EX (NCT07450690)
- Testing
- Unilateral high-intensity interval training (HIIT)
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Sciatica, Low Back Pain
Effects of Extension Biased External Limb Loading in Addition to McKenzie Extension Protocol in Lumbar Derangement Syndrome
Low back pain is one of the most common problem affecting one's daily living activities. McKenzie Method of Mechanical Diagnostic Therapy (MDT) is an appealing modality of treatment.
- Conditions
- Sciatica, Low Back Pain, Low Back Pain, Mechanical
- Trial name
- NCT04155450
- Testing
- Extension Biased External Limb Loading Exercises, McKenzie Extension Exercise Protocol, Moist Heat
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people
- Sponsor
- Foundation University Islamabad
Diabetes Mellitus Type 2
MOE and DNSE Effects on Balance and Activities of Daily Living Diabetic Peripheral Neuropathy
The purpose of this study is to compare the impact of Modified Otago Exercises and Dynamic Neuromuscular Stabilization Exercises on patients with diabetic peripheral neuropathy (DPN) using valid tools such as the Berg Balance…
- Trial name
- NCT07293507
- Testing
- Modified Otago Exercises, Dynamic neuromuscular stabilization exercises
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Overweight and Obesity, Inflammation; Muscle
Influence of Aerobic Training and Weight Loss on Skeletal Muscle Inflammatory Markers and Muscle Protein Balance in Older Adults
It is estimated that 15% of adults aged 60-70 years, and up to 50% of adults aged 80 years and older are affected by sarcopenia-the age related loss of muscle mass and function.
- Conditions
- Overweight and Obesity, Inflammation; Muscle, Sedentary Lifestyle
- Trial name
- NCT03743675
- Testing
- Diet-Induced Weight Loss, Aerobic Exercise Training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Miami University
Sciatica Pain, Sciatica
Effects of SSMC With and Without Myofascial Release in Patients With Sciatica
Sciatica involves a radiating pain along the sciatic nerve, extending from the lower back through the hips and buttocks to each leg.
- Trial name
- Sciatica (NCT06696898)
- Testing
- Somatosensory Motor Control Exercises, Myofascial Release Technique, Sensorymotor training
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Riphah International University
The Effects of Neuromuscular Electrical Stimulation on Exercise Performance
NMES Effects on Substrate Metabolism and IGF-1
The aim of this study is to investigate whether neuromuscular electrostimulation (NMES) training coupled with high-intensity interval training (HIIT) and moderate intensity continuous aerobic training has an effect on the…
- Trial name
- NCT06850532
- Testing
- IGF-1
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mersin University
Cirrhosis, Liver, Liver Transplant Surgery
Online Prehabilitation for Patients Awaiting Liver Transplantation
Physical frailty is common in patients awaiting liver transplantation and has been associated with poor health outcomes. There is promising data from small studies showing that behavioural, nutrition, exercise therapy…
- Conditions
- Cirrhosis, Liver, Liver Transplant Surgery, Liver Disease
- Trial name
- OPAL (NCT05899231)
- Testing
- Prehabilitation Programming
- Where
- 6 sites in Canada
- Volunteers
- 177 people
- Sponsor
- University of Alberta
Shin Splint, Running-related Injury
Gait-Training Using Wearable Sensors
The overarching purpose of this project is to use sensor-derived patterns to guide running interventions during in-field training scenarios for runners with exercise-related lower leg pain.
- Trial name
- NCT04270565
- Testing
- In-Field Gait-Training, Home Exercise
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Peripheral Neuropathy
Effect of Hands and Feet Exercises on Taxane Based Chemotherapy Induced Peripheral Neuropathy in Patients With Solid Tumors
The goal of this clinical trial is to determine whether hand and foot exercises can reduce the severity of Taxane-based chemotherapy-induced peripheral neuropathy (CIPN) in adult cancer patients aged 20-60 years who have Grade 1I…
- Trial name
- NCT07321236
- Testing
- Structured Hand and Foot Exercises
- Volunteers
- 58 people
- Sponsor
- University of Health Sciences Lahore
Muscle Recovery, Muscle Soreness
Effect of PEA on Muscle Recovery Following Resistance Exercise
This study evaluates the effects of short term palmitoylethanolamide (PEA) supplementation on functional responses (i.e. muscle soreness and performance parameters) to strenuous eccentric exercise, and investigateq the systemic…
- Trial name
- NCT05753111
- Testing
- PEA
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Sarcopenia
Home-based Progressive Resistance Exercise to Enhance Physical Performance of Older Adults With Possible Sarcopenia
The overall aim of the proposed project is to improve muscle strength in older adults with possible sarcopenia by promoting home-based progressive resistance exercise.
- Trial name
- NCT04851262
- Testing
- Exercise
- Where
- Hong Kong
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Sarcopenia, Frailty
Resistance Exercise Training at Different Intensities
The aim of the current study, therefore, is to determine the feasibility of recruitment and adherence to resistance exercise training interventions performed at low and high loads, to volitional muscular failure, in a trial…
- Conditions
- Sarcopenia, Frailty, Aging
- Trial name
- NCT04053920
- Testing
- Low Load Resistance exercise, High Load Resistance exercise
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Chemotherapy Induced Peripheral Neuropathy (CIPN), Peripheral Neuropathy Due to Chemotherapy
Feasibility Testing of a Tai Chi Program for Chemotherapy-Induced Peripheral Neuropathy Treatment (TCT)
This research is being done to determine whether a 12-week virtual Tai Chi training program, designed to improve balance and small nerve fiber function, is feasible and acceptable among cancer survivors with chemotherapy-induced…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Peripheral Neuropathy Due to Chemotherapy, Peripheral Neuropathies, Neuropathy
- Trial name
- NCT06807294
- Testing
- Tai Chi Program
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Dana-Farber Cancer Institute
Sarcopenia
Effects of Omega-3 and Whey Protein Supplementation on Lean Mass in Older Adults
To evaluate the effect of omega-3 supplementation combined with whey protein intake on lean mass, muscle strength, metabolomic and lipidomic profiles, and biomarkers of oxidative stress and inflammation in older adults undergoing…
- Trial name
- W-3 and Whey (NCT05862779)
- Testing
- Omega 3 + Whey Protein
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Inflammatory Bowel Diseases, Sarcopenia
The Efficacy of Exercise Therapy in Patients With Inflammatory Bowel Disease
this study aims to determine the effect of 8 weeks of exercise on the quality of life and muscle strength of patients with IBD. Patients will be randomized into 1) Intervention group: doing aerobic and resistance exercise…
- Trial name
- NCT05455762
- Testing
- Exercise
- Where
- Iran
- Volunteers
- 56 people
- Sponsor
- Tehran University of Medical Sciences
Chronic Low-back Pain
Multichannel Neuromuscular Electrical Stimulation With Core Exercise for Chronic Low Back Pain
Chronic non-specific low back pain is a common musculoskeletal condition that can adversely affect daily activities, functional capacity, sleep, and quality of life.
- Trial name
- NCT07760142
- Testing
- Core exercise program, StimaWELL 120MTRS - lumbar strengthening program, StimaWELL 120MTRS - muscle relaxation program
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Uskudar University
End Stage Liver Disease, Sarcopenia
Exercise Intervention in Liver Transplant Patients
The purpose of this study is to learn more about the effects of exercise on functional status and outcomes on patients with end-stage liver disease on the liver transplant waiting list and who have undergone liver transplantation.
- Conditions
- End Stage Liver Disease, Sarcopenia, Liver Cirrhoses
- Trial name
- NCT02367092
- Testing
- Exercise Program
- Where
- 3 sites in United States
- Volunteers
- 83 people
- Sponsor
- University of California, San Francisco
Fibromyalgia, Exercise
Cardiovascular Autonomic Function and Endogenous Pain Modulation
The study has three aims: 1. To investigate the influence of cardiovascular autonomic function on pain sensitivity at rest in patients with fibromyalgia and age- and sex-matched controls 2.
- Conditions
- Fibromyalgia, Exercise, Pain, Autonomic Dysfunction
- Trial name
- NCT03911609
- Testing
- Exercise, Cognitive Task
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Marquette University
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