Clinical trials: Neuromuscular Signs and Symptoms
Myalgic Encephalomyelitis, Long-COVID
Low Dose Rapamycin in ME/CFS, Long-COVID, and Other Infection Associated Chronic Conditions
The goal of this observational study is to assess the clinical response and the effect of autophagy function in patients before, during and throughout oral low dose sirolimus (rapamycin) therapy.
- Trial name
- NCT06257420
- Testing
- Rapamycin
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- Simmaron Research Inc.
Sciatica, Chronic Sciatica
Effects of Shockwave Therapy Versus Ultrasound Therapy Among Patients With Chronic Sciatica
Sciatica is characterized by radiating pain, functional limitations, reduced flexibility, disturbed sleep, and impaired quality of life.
- Conditions
- Sciatica, Chronic Sciatica, Lumbar Radiculopathy
- Trial name
- NCT07710924
- Testing
- Extracorporeal Shockwave Therapy, Therapeutic Ultrasound, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- University of Lahore
Post-Herpetic Neuralgia (PHN), Neuropathic Pain
A Study Into Pain Relief Given by ASP8477 for Peripheral Neuropathic Pain (Either Post-herpetic Neuralgia or Painful Diabetic Peripheral Neuropathy) and Its Safety
The purpose of this study is to assess the painkilling efficacy of ASP8477 relative to mock (placebo) in patients that have been diagnosed with painful diabetic peripheral neuropathy or postherpetic neuralgia determined by the…
- Conditions
- Post-Herpetic Neuralgia (PHN), Neuropathic Pain, Painful Diabetic Peripheral Neuropathy (PDPN)
- Trial name
- MOBILE (NCT02065349)
- Testing
- ASP8477
- Where
- 17 sites in Czechia, Germany and 2 more
- Volunteers
- 132 people
- Sponsor
- Astellas Pharma Europe B.V.
Stroke, Hemiplegia, Spastic
Condensed and Distributed Robotic Therapy in Spastic Stroke Post Botulinum Toxin Injection
The purpose of this project is to examine and compare the immediate and long-term effects of combined Botulinum toxin type A (BoNT-A) injection between condensed and distributed robot-assisted training (RT) programs in patients…
- Trial name
- NCT03321097
- Testing
- condensed RT group, distributed RT group
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Chang Gung Memorial Hospital
Sarcopenia
Smart Tech-Based Nutrition and Exercise for Sarcopenia Risk.
Sarcopenia, characterized by muscle loss and weakness, is a major health issue among older adults and impacts mobility and quality of life.
- Trial name
- S-TEN (NCT07230210)
- Testing
- The 12-week exercise component is delivered via the dedicated Line Bot platform. It includes three progressive exercise training videos (resistance, balance) . Participants are in
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- HSIAO MEI LAN
Spinal Cord Injuries, Spinal Cord Diseases
Impact of Peripheral Afferent Input on Central Neuropathic Pain
The overarching aim of this study is to investigate the contribution of peripheral afferent input to spontaneous and evoked central neuropathic pain after a spinal cord lesion or disease.
- Conditions
- Spinal Cord Injuries, Spinal Cord Diseases, Syringomyelia
- Trial name
- NCT05646810
- Testing
- Lidocaine (10 mg/ml), Isotonic saline
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Inactivity, Physical, Treatment Adherence and Compliance
VR vs. Conventional Cycling Exercise for Geriatric Inpatient Physical Activation
The aim of this study is to investigate whether virtual reality assisted stationary cycling exercise results in more physical activity than conventional unsupervised stationary cycling exercise.
- Conditions
- Inactivity, Physical, Treatment Adherence and Compliance, Hospital Acquired Condition, Sarcopenia
- Trial name
- NCT05123638
- Testing
- Virtual reality cycling exercise, Unsupervised stationary cycling exercise
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Bispebjerg Hospital
Whiplash Associated Disorders (WAD), Whiplash
Neuromuscular Mechanisms Underlying Poor Recovery From Whiplash Injuries
This study is investigating whether changes in the shape and size of bodily muscles and spinal cord anatomy can influence recovery rates following a motor vehicle collision (MVC).
- Trial name
- NCT02157038
- Testing
- Pedometer, MRI
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Northwestern University
Stroke
rTMS and Robotic Gait Training in Patients With Stroke
Patients with stroke have demonstrated abnormal muscle tone and postural control ability which affect their ambulation, activity of daily living and confident.
- Trial name
- NCT03817385
- Testing
- repetitive TMS, robotic GT
- Where
- Taiwan
- Volunteers
- 105 people
- Sponsor
- Changhua Christian Hospital
Postoperative Pain, Postherniotomy Pain
Neurophysiological Characterization of Postherniotomy Pain
Sensory function is different in persistent postherniotomy pain patients than in operated controls, suggesting this to be a neuropathic pain syndrome.
- Conditions
- Postoperative Pain, Postherniotomy Pain, Neuropathic Pain
- Trial name
- NCT00719368
- Where
- 2 sites in Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Neuropathic Pain
Topical Lidocaine: Predictors of Response in Peripheral Nerve Injury
The primary purpose is to study the predictive value of preserved nociceptors and large afferent fibers and dynamic mechanical allodynia on the effect of lidocaine patch.
- Trial name
- NCT01112748
- Testing
- Topical lidocaine patch
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Danish Pain Research Center
Herpes Zoster, Postherpetic Neuralgia
The Superiority of Contralateral Oblique View for Mid-thoracic Epidural Assess
The aim of the present study is to compare contralateral oblique view with the lateral view for fluoroscopic guided mid-thoracic epidural assess.
- Conditions
- Herpes Zoster, Postherpetic Neuralgia, Cancer
- Trial name
- NCT03789955
- Testing
- Fluoroscopic-guided TEB
- Where
- 2 sites in South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Septic Shock, Adverse Event
Early Versus Conventional Cessation of Hydrocortisone in Septic Shock
Septic shock is one of the causes of death in ICU and hospital. Refractory shock is the problem which healthcare providers should recognize though it is difficult to handle with.
- Conditions
- Septic Shock, Adverse Event, Hydrocortisone, Hyperglycemia
- Trial name
- CESSHYDRO (NCT05818826)
- Testing
- normal saline solution, Hydrocortisone and normal saline solution
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Mahidol University
Health Literacy, Middle Aged
Health Literacy-Based Multifactorial Program for Adults With Sarcopenia
Sarcopenia is a common age-related condition characterized by the progressive loss of muscle mass and function, which may lead to reduced physical performance, disability, and poorer quality of life.
- Conditions
- Health Literacy, Middle Aged, Elderly (People Aged 65 or More), Exercise Therapy
- Trial name
- NCT07654478
- Testing
- Multicomponent Intervention
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Spinal Cord Injury, Chronic Neuropathic Pain
VIRTUAL WALKING AND TRANSCRANIAL DIRECT CURRENT STIMULATION FOR CHRONIC NEUROPATHIC PAIN DUE TO SPINAL CORD INJURY
The goal of this feasibility study is to assess the feasibility of the combined treatment intervention "virtual walking (VW) and transcranial direct current stimulation (tDCS)" of neuropathic pain in patients with spinal cord…
- Trial name
- NCT06710808
- Testing
- Virtual walking and transcranial direct current stimulation
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Lumbar Radiculopathy, Hoffman's Reflex
High-power Laser Versus Pulsed Electromagnetic Therapy in Lumbar Radiculopathy.
To compare between high-power laser versus pulsed electromagnetic therapy on pain and Hoffman reflex in lumbar radiculopathy.
- Conditions
- Lumbar Radiculopathy, Hoffman's Reflex, Pulsed Electromagnetic Therapy, Laser Therapy
- Trial name
- NCT07393750
- Testing
- high-power laser, Pulsed electromagnetic field, physiotherapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Neuropathic Pain
Neuropathic Pain Database
To establish the infrastructure for a national neuropathic pain database. To determine the longterm outcome of the management of chronic neuropathic pain including pain relief, disability, and quality of life.
- Trial name
- NePDatabase (NCT00669006)
- Where
- Canada
- Volunteers
- 789 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pain, Neuropathic, Failed Back Surgery Syndrome
Coordinated Reset Spinal Cord Stimulation
The goal of this study is to evaluate whether a new spinal cord stimulation paradigm, called Coordinate Reset (CR) Stimulation, can provide equivalent or better pain relief with reduced energy requirements.
- Trial name
- NCT04997278
- Testing
- Coordinated Reset spinal cord stimulation
- Where
- United States
- Sponsor
- Stanford University
Malnutrition, Sarcopenia
Evaluation of an Oral Nutritional Supplement Containing AN777
To evaluate the effect of an experimental oral nutritional supplement containing AN777 compared to another oral nutritional supplement in a malnourished, elderly population.
- Trial name
- NCT01191125
- Testing
- medical food with AN777, oral nutritional formula
- Where
- 23 sites in United States, Belgium and 6 more
- Volunteers
- 331 people
- Sponsor
- Abbott Nutrition
Low Back Pain
Neuromuscular Balance in Low Back Pain
The research was an interventional study with a quantitative board, fulfilled in a private clinique specialized in trauma service; it was formed between august to October of 2006.
- Trial name
- NCT00752674
- Testing
- Neuromuscular balance
- Volunteers
- 12 people
- Sponsor
- Fortaleza University