Clinical trials: Neuropathic Facial Pain
Trigeminal Neuralgia (Burchiel Type I), Trigeminal Neuralgia (Burchiel Type II)
Motor Cortex Stimulation for the Treatment of Chronic Facial, Upper Extremity, and Throat Pain.
This study is an open-label study to determine the feasibility of Motor Cortex Stimulation (MCS) in the treatment of patients with chronic pain of the face or upper extremity.
- Conditions
- Trigeminal Neuralgia (Burchiel Type I), Trigeminal Neuralgia (Burchiel Type II), Trigeminal Neuropathic Pain, Trigeminal Deafferentation Pain
- Trial name
- NCT02321566
- Testing
- Epidural Motor Cortex Stimulation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Johns Hopkins University
Oral-facial Pain
Impact of Palmitoylethanolamide (PEA) in the Management of Oro-facial Pain
Pain is the most common symptom faced by dentists, whether acute (pulpitis, acute periodontitis, post-surgical, etc.) or chronic (chronic periodontitis, muscle pain, TMJ disorders, BMS, OLP, etc.).
- Trial name
- NCT05877170
- Testing
- Palmitoyletinolamide
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Catania
Neuropathic Pain, Orofacial Pain
Bilateral TMS vs. Unilateral TMS
Rationale: In 2016, Henssen et al. discuss that orofacial pain may be conducted in a bilateral fashion, inducing activation of both thalami [1].
- Conditions
- Neuropathic Pain, Orofacial Pain, Trigeminal Neuropathy
- Trial name
- biTMSvsuniTMS (NCT03710967)
- Testing
- Transcranial magnetic stimulation
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Radboud University Medical Center
Atypical Facial Pain or Atypical Odontalgia
Assessment and Treatment Patients With Atypical Facial Pain Trough Repetitive Transcranial Magnetic Stimulation
Atypical Facial Pain is a chronic condition and presents controversies during diagnostic and treatment, between specialist not have consensus about the pathophysiology.
- Trial name
- EMTr-AFP (NCT01746355)
- Testing
- rTMS
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Neuropathic Pain, Orofacial Pain
Pain and Perceptual Distortion of Face
Post-traumatic trigeminal neuropathic pain (PTNP) is "a unilateral or bilateral facial or oral pain following and caused by trauma to the trigeminal nerve(s), with other symptoms and/or clinical signs of trigeminal nerve…
- Trial name
- NCT06577649
- Testing
- Active repetitive transcranial magnetic stimulation (rTMS)
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Trigeminal Neuralgia, Pain, Neuropathic
FMRI Assessment After Radiofrequency in Trigeminal Neuralgia
To investigate the brain activations related to TN, using fMRI, and to evaluate changes in these activations following the application of pulsed and thermal Radiofrequency lesioning to the gasserien ganglion.
- Trial name
- NCT03305289
- Testing
- pulsed Radiofrequency, thermal Radiofrequency
- Volunteers
- 20 people
- Sponsor
- Assiut University
Trigeminal Neuralgia, Neuropathic Pain
Nucleo CMP and Neurorubine Versus Carbamazepine for Classical Trigeminal Neuralgia
Trigeminal neuralgia is a severe facial pain condition that significantly impacts quality of life. While the standard medication, carbamazepine, provides relief, it is often associated with side effects and rapid pain recurrence…
- Trial name
- NCT07304453
- Testing
- Conventional Carbamazepine Therapy, Nucleo CMP and Neurorubine Combination
- Where
- Iraq
- Volunteers
- 38 people
- Sponsor
- Karbala University
Nerve Injury, Orofacial Pain
Post-traumatic Neuropathy of the Trigeminal Nerve
This is retrospective research mainly aims to determine the patterns of symptoms, clinical and radiological findings and outcomes in patients with trigeminal neuropathy following trauma or iatrogenic damage and how this…
- Conditions
- Nerve Injury, Orofacial Pain, Trigeminal Nerve Injuries, Trigeminal Neuropathy
- Trial name
- NCT04612855
- Testing
- Groupwise comparison of primary and secondary outcomes
- Where
- Belgium
- Volunteers
- 1,333 people
- Sponsor
- KU Leuven
Trigeminal Neuralgia, Facial Pain
Emotion and Memory in Chronic Neuropathic Pain
Chronic pain affects one in four Canadians, leading to severe personal and societal costs. Over 70% of chronic pain patients report memory difficulties and fear having unexpected pain.
- Trial name
- NCT06518421
- Testing
- Neuropsychological assessments, MR Imaging
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Trigeminal Neuralgia
Comparison of Pulsed and Thermal Radiofrequency for Trigeminal Neuralgia
The goal of this clinical trial is to compare the effectiveness of Pulsed Radiofrequency (PRF) with Pulsed and Thermal Radiofrequency (PRF + TRF) in treating Trigeminal Neuralgia (TN) in adults.
- Trial name
- NCT06684275
- Testing
- Pulsed Radiofrequency (PRF), Pulsed and Thermal Radiofrequency (PRF + TRF)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Chronic Neuropathic Pain, Post-Stroke Pain
Transcranial Magnetic Stimulation for Chronic Neuropathic Pain
Chronic neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory nervous system. It is highly prevalent, debilitating, and challenging to treat.
- Conditions
- Chronic Neuropathic Pain, Post-Stroke Pain, Trigeminal Neuralgia, Nerve Injury
- Trial name
- NCT05593237
- Testing
- High Frequency rTMS, Low Frequency rTMS
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Postherpetic Neuralgia, Peripheral Neuropathic Pain
Clinical Trial of the Safety and Efficacy of Peripheral Nerve Stimulation in the Treatment of Peripheral Neuropathic Pain.
The goal of this clinical trial is to evaluate safety and efficacy of percutaneous peripheral nerve stimulation in patients with peripheral neuropathic pain. The main questions it aims to answer are: 1.
- Conditions
- Postherpetic Neuralgia, Peripheral Neuropathic Pain, Trigeminal Neuralgia
- Trial name
- NCT06290661
- Testing
- Active electrostimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Pain, Neuropathic
Stellate Ganglion Block in Herpes Zoster
Patient who will be presented to Tanta University Hospitals complaining of acute herpes zoster with onset of vesicular eruption less than 7 days will be included in this clinical study.
- Trial name
- NCT04188327
- Testing
- Stellate ganglion block
- Where
- 3 sites in Egypt
- Volunteers
- 208 people
- Sponsor
- Tanta University
Central Post-stroke Pain, Neuropathic Pain
Thalamic-Burst-DBS for Neuropathic Pain
Central post-stroke pain (CPSP) is a neuropathic pain syndrome and one of the major sequelae after ischemic or hemorrhagic cerebral stroke.
- Trial name
- NCT05204472
- Testing
- Burst DBS, Tonic DBS
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Facial Pain
Clinical Trial of Wireless CranioFacial Nerve Stimulation (CFNS) for the Treatment of CranioFacial Neuropathic Pain
The purpose of this study is to assess the effectiveness of craniofacial nerve stimulation for the treatment of neuropathic pain.
- Trial name
- NCT02729480
- Testing
- Halo Craniofacial Nerve Stimulator System
- Where
- 7 sites in United States
- Volunteers
- 60 people
- Sponsor
- Curonix LLC
Atypical Facial Pain, Persistent Idiopathic Facial Pain
Efficacy and Safety of ATNC05 in Treatment of Atypical Facial Pain
The purpose of the study is to test the efficacy of ATNC05 in the treatment of Atypical Facial Pain (AFP), also known as Persistent Idiopathic Facial Pain (PIFP).
- Conditions
- Atypical Facial Pain, Persistent Idiopathic Facial Pain, Atypical Trigeminal Neuralgia, Neuropathic Orofacial Pain
- Trial name
- AFP (NCT01920087)
- Testing
- ATNC05
- Where
- United States
- Sponsor
- Allodynic Therapeutics, Inc
Neuropathic Pain
Study of MRgFUS Exablate Treatment Following the Neuropathic Pain
The objective of this study is to capture the change in pain intensity, physical/emotional function, and pain impact for patients diagnosed with neuropathic pain who undergo an Exablate treatment.
- Trial name
- NCT04649554
- Testing
- Exablate treatment
- Where
- Italy
- Volunteers
- 2 people
- Sponsor
- InSightec