Clinical trials: Neuropathic Pain
Multiple Sclerosis
Sativex Versus Placebo When Added to Existing Treatment for Central Neuropathic Pain in MS
The purpose of this study is to find out if cannabis-based medicine compared to a dummy medicine (placebo that contains no active ingredient) can help the central neuropathic pain patients experience as a result of multiple…
- Trial name
- NCT00391079
- Testing
- Sativex
- Where
- 6 sites in Canada
- Volunteers
- 339 people
- Sponsor
- GW Pharmaceuticals Ltd
Chronic Pain Syndrome
Post-reimbursement Study to Follow Spinal Neurostimulator Devices for Pain Therapy (French SCS Registry)
Observational study to evaluate the long term efficacy of Spinal Cord Stimulation (SCS) over 2 years following SCS implant. This study is requested by French Health Authorities for reimbursement renewal, to maintain reimbursement…
- Trial name
- SME (NCT01778426)
- Where
- France
- Volunteers
- 414 people
- Sponsor
- MedtronicNeuro
Neuralgia,Postherpetic
Safety and Efficacy of Gabapentin in Postherpetic Neuralgia
Gabapentin and pregabalin are treatments for some types of neuropathic pain, including postherpetic neuralgia (PHN). However, these treatments usually need to be taken 3 times a day for effective pain control.
- Trial name
- NCT00636636
- Testing
- Gabapentin Extended Release tablets
- Where
- 39 sites in United States, Argentina and 1 more
- Volunteers
- 452 people
- Sponsor
- Depomed
Central Neuropathic Pain, Multiple Sclerosis
Safety and Efficacy of AVP-923 in the Treatment of Central Neuropathic Pain in Multiple Sclerosis
The objectives of the study are to evaluate the safety, tolerability, and efficacy of 3 doses of AVP-923 capsules in the treatment of central neuropathic pain in participants with multiple sclerosis.
- Trial name
- PRIME (NCT01324232)
- Testing
- AVP-923-45, AVP-923-30, AVP-923-20
- Where
- 72 sites in United States, Argentina and 3 more
- Volunteers
- 209 people
- Sponsor
- Avanir Pharmaceuticals
Chronic Neuropathic Pain in the Low Back and Legs
Field Shape and Amplitude Sensitivity Exploratory Study (CONTOUR Study)
The study aims to better understand how to program Spinal Cord Stimulation for the treatment of chronic low back and leg pain
- Trial name
- NCT02916498
- Testing
- Boston Scientific's Precision SPECTRA™ Spinal Cord Stimulation System
- Where
- 2 sites in United Kingdom
- Volunteers
- 16 people
- Sponsor
- Boston Scientific Corporation
Pain, Peripheral Neuropathy
A Study to Compare the Safety and Tolerability of Sativex® in Patients With Neuropathic Pain.
The purpose of this study is to assess the safety and tolerability of long term therapy with Sativex® in relieving neuropathic pain.
- Trial name
- NCT00713323
- Testing
- Sativex®
- Where
- United Kingdom
- Volunteers
- 380 people
- Sponsor
- Jazz Pharmaceuticals
Spinal Cord Injuries, Spinal Cord Diseases
Vaporized Cannabis and Spinal Cord Injury Pain
This study will demonstrate that vaporized marijuana results in antinociception when compared to placebo in subjects with spinal cord injury.
- Trial name
- NCT01555983
- Testing
- Vaporization of Cannabis
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Barth Wilsey
Cancer
A Randomized Phase III Study of Vitamins B6 and B12 to Prevent Chemotherapy-Induced Neuropathy in Cancer Patients
Many types of chemotherapy may cause nerve damage as a side effect. This neurotoxicity can manifest as peripheral sensory neuropathy (characterized by numbness, tingling, or pain).
- Trial name
- NCT00659269
- Testing
- Multivitamin (MV), Multivitamin + Vitamin B12 + Vitamin B6, Chemotherapy
- Where
- 5 sites in United States
- Volunteers
- 319 people
- Sponsor
- New Mexico Cancer Research Alliance
Cannabis, HIV Neuropathy
Effect of Cannabis and Endocannabinoids on HIV Neuropathic Pain
Acute cannabis administration is reported to alleviate HIV neuropathic pain (HIV-NP), but there is limited knowledge about the effects of cannabis constituents (delta-9 tetrahydrocannabinol/THC and cannabidiol/CBD), the…
- Conditions
- Cannabis, HIV Neuropathy, Pain Syndrome
- Trial name
- NCT03099005
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of California, San Diego
Pain, Neuropathic, Epilepsy
Cancer in Patients With Gabapentin (GPRD)
High doses of gabapentin are associated with pancreatic acinar cell tumors in rats, but there has been no post marketing pancreatic carcinogenicity signal with gabapentin as reported by spontaneous reports in AERS or in the…
- Conditions
- Pain, Neuropathic, Epilepsy, Renal Pelvis Cancer, Pancreatic Cancer
- Trial name
- NCT01236053
- Testing
- Gabapentin prescriptions
- Volunteers
- 2,323,608 people
- Sponsor
- GlaxoSmithKline
Pain, Peripheral Neuropathy
A Study of Sativex® for Pain Relief of Peripheral Neuropathic Pain, Associated With Allodynia
The purpose of this study is to evaluate the efficacy of Sativex® compared with placebo in relieving peripheral neuropathic pain associated with allodynia.
- Trial name
- NCT00710554
- Testing
- Sativex
- Where
- United Kingdom
- Volunteers
- 246 people
- Sponsor
- Jazz Pharmaceuticals
Neuropathic Pain, Mechanical Hypersensitivity
AZD2066 Neuropathic Pain - Mechanical Hypersensitivity
The purpose of this study is to investigate if 28 days of treatment with AZD2066 compared to placebo can relieve the pain arising from the nervous system when the patients are touched by something that should not cause pain or…
- Trial name
- NP-MH (NCT00939094)
- Testing
- AZD2066
- Where
- 38 sites in United States
- Volunteers
- 87 people
- Sponsor
- AstraZeneca
Neuropathic Pain
Effect of Eslicarbazepine Acetate on the Pharmacokinetics of Metformin in Healthy Volunteers
The primary objective was to investigate whether multiple-dose administration of eslicarbazepine acetate affects the pharmacokinetics of metformin.
- Trial name
- NCT00971295
- Testing
- Metformin, Eslicarbazepine acetate
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Diabetic Peripheral Neuropathic Pain
Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Diabetic Peripheral Neuropathic Pain
This study is being done to test the safety and efficacy of the study drug LY3016859 for the treatment of diabetic peripheral neuropathic pain.
- Trial name
- NCT04476108
- Testing
- LY3016859
- Where
- 36 sites in United States, Puerto Rico
- Volunteers
- 125 people
- Sponsor
- Eli Lilly and Company
Neuralgia, Postherpetic
A Study of the Safety and Efficacy of AGN-214868 in Patients With Postherpetic Neuralgia
This study will evaluate the safety and efficacy of AGN-214868 in patients with postherpetic neuralgia (PHN) - nerve pain.
- Trial name
- NCT01129531
- Testing
- AGN-214868
- Where
- 4 sites in United States, Czechia and 2 more
- Volunteers
- 294 people
- Sponsor
- Allergan
Chronic Refractory Neuropathic Pain
An Open-label Continuation Trial to Assess the Continued Efficacy and Safety of Ascending Doses of Lacosamide in Subjects With Chronic Refractory Neuropathic Pain
This trial is the follow-on trial to a preceeding open-label trial which included patients with chronic refractory neuropathic pain. It is conducted at one site in the United Kingdom and the patient enrollment is completed.
- Trial name
- NCT00237458
- Testing
- Lacosamide
- Where
- Germany
- Volunteers
- 7 people
- Sponsor
- UCB Pharma
Neuralgia, Myalgia
Safety and Efficacy of Cunermuspir on Energy, Strength, and Fatigue in Patients With Nerve or Muscle Pain
Male and female participants were selected based on chronic neuromuscular pain. Patients were instructed to take two doses of the placebo or cuprous nicotinic acid chelate Cunermusmir twice a day for 28 days.
- Trial name
- NCT04737278
- Testing
- Cunermuspir
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- Mitosynergy LLC
Neuropathic Pain, Amputation
The SNAP Trial: SPRINT® Peripheral Nerve Stimulation for the Treatment of Neuropathic Post-Amputation Pain
The purpose of this study is to determine if pain can be relieved by delivering small amounts of electricity (called "electrical stimulation") to the nerves in an individual's amputated leg.This study will involve the use of a…
- Trial name
- SNAP (NCT03783689)
- Testing
- SPRINT Peripheral Nerve Stimulation (PNS) System
- Where
- 14 sites in United States
- Volunteers
- 38 people
- Sponsor
- SPR Therapeutics, Inc.
Pain
A Methodology Study Of Brain Imaging Of Pain-Killers In Post-Traumatic Neuropathic Pain Patients
This study is a methodology study designed to discover whether a brain imaging technology is a better way of compare the relative sensitivities of fMRI and subjective psychometric assessments of pain to multiple doses of…
- Trial name
- NCT00610155
- Testing
- Pregabalin, Tramadol SR
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Sciatica, Back Pain
Herniectomy Versus Herniectomy With a Spinal Stabilization System for the Treatment of Complex Disc Disease
The study aims at assessing the short and long-term effectiveness and patient perception of benefit with the use of a DIAM™ Spinal Stabilization System in the treatment of complex disc disease at a single level from L2 to L5.
- Trial name
- NCT00749996
- Testing
- DIAM™ Spinal Stabilization System, Herniectomy
- Where
- 19 sites in Belgium, Czechia and 6 more
- Volunteers
- 165 people
- Sponsor
- Medtronic Spinal and Biologics