Clinical trials: Neuropathic Pain Management, open to volunteers
Spinal Cord Injuries (SCI), Chronic Pain
Virtual Reality-Based Hypnotherapy for Pain, Sleep, and Mood in Spinal Cord Injury
The goal of this clinical trial is to learn whether virtual reality (VR)-based hypnotherapy, added to conventional physiotherapy, improves pain, sleep, mood, and quality of life in adults with chronic spinal cord injury.
- Conditions
- Spinal Cord Injuries (SCI), Chronic Pain, Neuropathic Pain, Sleep Disturbance
- Trial name
- HypnoVR-SCI (NCT07846410)
- Testing
- Virtual Reality-Based Hypnotherapy, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Pulmonary Dysfunction, Median Sternotomy Recovery
FROST-STERN Trial: A Trial of Intraoperative Cryoablation for Post Operative Pain Management After Full Sternotomy
Background and Rationale: Open-heart surgery via a median sternotomy is associated with severe acute postoperative pain. This pain can impair a patient's ability to take deep breaths and cough effectively which increases the risk…
- Conditions
- Pulmonary Dysfunction, Median Sternotomy Recovery, Postoperative Pain
- Trial name
- FROST-STERN (NCT07637370)
- Testing
- Intercostal Nerve Cryoablation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rutgers, The State University of New Jersey
Post-Herpetic Neuralgia
Comparison Between the Efficacy of Ultrasound-guided Erector Spinae Plane Block and Conventional Treatment for Pain Management in Patients With Post-herpetic Neuralgia
The present study aims to evaluate the efficacy of ultrasound-guided erector spinae plane block with steroids to relieve pain in cases of post-herpetic neuralgia, patient satisfaction, and record any complications post-injection.
- Trial name
- NCT07256145
- Testing
- erector spinae plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Neuropathic Pain Management
tACS for Neuropathic Pain Management After SCI
The overall goal is to investigate the effectiveness of a novel intervention - transcranial alternating current stimulation (tACS) for neuropathic pain management in people after spinal cord injury.
- Trial name
- NCT06029075
- Testing
- tACS 10Hz, tACS 20Hz
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The University of Texas Health Science Center, Houston
Diabetic Peripheral Neuropathic Pain (DPN)
Medtronic Inceptiv™ Closed-Loop DTM Spinal Cord Stimulation for Painful Diabetic Peripheral Neuropathy
This study is conducted to evaluate a new way of using spinal cord stimulation (SCS) in people with painful diabetic peripheral neuropathy (DPN).
- Trial name
- MED DPN (NCT07209514)
- Testing
- Implantable SCS with Closed Loop mechanism
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- TriCity Research Center
Chemotherapy-induced Peripheral Neuropathy (CIPN), Neuropathic Pain
Use of PEA and Scutellaria in Synergy With Therapeutic Exercise in Chemotherapy-induced Peripheral Neuropathy (CIPN): a Clinical Trial
This study aims to find out if taking specific dietary supplements (PEA and Scutellaria) along with therapeutic exercise can help reduce nerve pain and damage caused by chemotherapy.
- Trial name
- NCT07352514
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Palermo
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Pelvic Pain Syndrome, Sacroiliac Disorder
Chronic Pelvic Pain in Females and Males
Pelvic pain is under-reported in healthy adults. Many patients with pelvic pain under-estimate the problem. Chronic pelvic pain can be managed properly, if diagnosed promptly.
- Conditions
- Pelvic Pain Syndrome, Sacroiliac Disorder, Piriformis Syndrome, Sacrococcygeal Disorder
- Trial name
- NCT06102733
- Testing
- Rehabilitation therapy
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Salem Anaesthesia Pain Clinic
Amputation, Traumatic, Pain, Phantom
Feasibility of Using an App for Managing Phantom Limb Pain Associated with Combat Injury in Ukraine (PAMELA)
In Ukraine, since the beginning of the full-scale war on February 24, 2022, a large number of individuals have lost a limb(s). Many of these amputees cannot access appropriate care in terms of pain management and rehabilitation.
- Conditions
- Amputation, Traumatic, Pain, Phantom, Pain, Acute, Pain, Chronic
- Trial name
- PAMELA (NCT06604507)
- Testing
- non-pharmacological app
- Where
- 5 sites in Ukraine
- Volunteers
- 200 people
- Sponsor
- Winfried Meißner
Complex Regional Pain Syndrome, Chronic Pain
Low Dose Naltrexone Therapy for Complex Regional Pain Syndrome
Complex Regional Pain Syndrome (CRPS) is a rare and often debilitating chronic pain condition whereby individuals may experience extreme sensitivity, discoloration, and swelling of the affected area -- along with numerous other…
- Conditions
- Complex Regional Pain Syndrome, Chronic Pain, Causalgia, Complex Regional Pain Syndrome Type I
- Trial name
- LDN-CRPS (NCT06306157)
- Testing
- Low dose naltrexone
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Hospital for Special Surgery, New York
Pain, Postoperative, Adult
Longitudinal Assessment of Pain-Related Patient-Reported Outcomes After Surgery
Little is known about pain-related outcomes experienced by patients in the first few weeks after surgery, once they are discharged from hospital.
- Conditions
- Pain, Postoperative, Adult, Pain Measurement, Functional Status
- Trial name
- NCT05315596
- Where
- 16 sites in Germany, Mexico
- Volunteers
- 1,000 people
- Sponsor
- Jena University Hospital
Neuropathic Pain Management, Diabetic Neuropathies, Painful
Beneficial Effects of Supplementation With CRONILIEF™ (Palmitoylethanolamide Phospholipids) in Diabetic Subjects With Neuropathic Pain.
This study aims to evaluate the potential benefit of an oral nutritional supplement based on CRONILIEF™ (Palmitoylethanolamide Phospholipids) in diabetic subjects with neuropathic pain, compared to a placebo.
- Conditions
- Neuropathic Pain Management, Diabetic Neuropathies, Painful, Palmitoylethanolamide
- Trial name
- NCT07377409
- Testing
- Cronilief™ (300 mg)
- Volunteers
- 70 people
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Neuropathic Pain
BreEStim Pre-trial
The overall goal is to evaluate the effectiveness of different stimulation protocol of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) in managing neuropathic pain after spinal cord injury (SCI).
- Trial name
- NCT07878429
- Testing
- Single-pulse BreEStim Treatment, Multiple-pulse BreEStim Treatment
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain
Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN)
Peripheral neuropathy is a disorder caused by damage to the peripheral nerves. Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of certain chemotherapy drugs, such as platinum-based compounds, taxanes…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain, CIPN - Chemotherapy-Induced Peripheral Neuropathy, Peripheral Neuropathic Pain
- Trial name
- NCT07072468
- Testing
- VMD-3866 Gel
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- VM Therapeutics LLC
Chronic Pain, Cancer Pain
UDOPAL Study: Home-Based Interventional Approach to Pain Management in Home-Hospitalized Patients
The UDOPAL Study proposes an innovative home-based care approach for the management of pain in patients admitted to the Home Hospitalization Unit (UHD).
- Conditions
- Chronic Pain, Cancer Pain, Neuropathic Pain, Palliative Care
- Trial name
- UDOPAL (NCT07265492)
- Testing
- UDOPAL model
- Volunteers
- 100 people
- Sponsor
- Hospital de Manises
Neuropathic Pain, Chronic Pain
Pediatric Electrocutaneous Analgesia for Children Experiencing Neuropathic Pain
This is a study evaluating the Scrambler Therapy device as a non-invasive treatment for neuropathic pain in pediatric oncology patients with metastatic bone disease.
- Trial name
- PEACE-NP (NCT07264920)
- Testing
- Scrambler Therapy MC-5A Device
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Johns Hopkins University
Myofacial Pain Syndrome, Clinical Decision Support
Artificial Intelligence Clinical Decision
The goal of this study is to investigate the effect of AI integration into clinical physical therapy clinical decision in improving cost effectiveness and clinical outcomes purposes of the study are: 1.
- Trial name
- AI/CDM (NCT07342790)
- Testing
- dry needling, neuromuscular facilitation (PNF) stretching, strengthening exercises (isometric & dynamic)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Chronic Pain, Pain Management
PREDICT-DOLOR VE: Validation of a Structured Triage Protocol for Chronic Pain
PREDICT-DOLOR VE is a structured clinical triage protocol for chronic pain that uses five internationally validated pain assessment instruments to help healthcare providers determine the appropriate level of care for patients…
- Conditions
- Chronic Pain, Pain Management, Neuropathic Pain
- Trial name
- PREDICT-VE (NCT07696676)
- Testing
- PREDICT-DOLOR VE
- Volunteers
- 120 people
- Sponsor
- Universidad Central de Venezuela