Clinical trials: Neuropathy, Diabetic
Diabetic Foot Infection, Osteomyelitis
A Clinical Trial Testing the Efficacy of PDT in Preventing Amputation in Diabetic Patients
The feet of diabetic patients continue to be an important problem in medicine. In general, patients with diabetic foot have some sort of amputation, especially in underserved populations.
- Conditions
- Diabetic Foot Infection, Osteomyelitis, Photo Antimicrobial Chemotherapy
- Trial name
- NCT03380403
- Testing
- PDT, Ciprofloxacin
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Faculdade de Medicina do ABC
Neuromuscular Transmission Disorder, Diabetes Mellitus, Type 2
Effect of Type II Diabetes Mellitus With Neuropathy on the Clinical Use of Rocuronium
International Diabetes Federation estimates that there are now 415 million adults aged 20-79 with diabetes mellitus worldwide. By 2040 this will rise to 640 million.
- Trial name
- NCT03737942
- Testing
- monitoring of neuromuscular function
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Diabetic Foot, Ulcer Foot
Diabetic Foot Ulcer Recurrence: Pilot Study
In this prospective pilot study, patients with DFU visiting the Indiana University Comprehensive Wound Center will be enrolled. Patients enrolled in the study will be followed for 16 weeks for wound closure(Phase A), and will…
- Trial name
- DFUCO (NCT03479242)
- Testing
- no interventions
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Indiana University
Diabetes Mellitus, Foot Ulcer
Exercise for People With Peripheral Neuropathy and Diabetic Foot Ulcers - a Case Series on Feasibility and Safety
Physical training is one of the cornerstones within the treatment of diabetes, as well as medicine and diet modification, and the effect is well documented.
- Trial name
- NCT04065724
- Testing
- Physical training as resistance and aerobic training.
- Where
- Denmark
- Volunteers
- 5 people
- Sponsor
- Københavns Kommune
Diabetic Foot Ulcer
Efficacy of LL-37 Cream on Bacteria Colonization, Inflammation Response and Healing Rate of Diabetic Foot Ulcers
Diabetic foot ulcer (DFU) is a common complication of diabetes with global prevalence of 6.3%. Treatment of diabetic foot ulcer (DFU) is challenging with disappointing outcome.
- Trial name
- NCT04098562
- Testing
- LL37, Standard Wound Care
- Where
- 3 sites in Indonesia
- Volunteers
- 40 people
- Sponsor
- Fakultas Kedokteran Universitas Indonesia
Diabetes Mellitus, Type 2, Diabetic Peripheral Neuropathy
Muscle and Bone in Patients with Diabetes Mellitus and Neuropathy
The goal of this observational study is to evaluate muscle fiber type composition in people with type 2 diabetes mellitus (T2DM) with a common complication of T2DM: diabetic peripheral neuropathy (DNP), specifically diabetic…
- Conditions
- Diabetes Mellitus, Type 2, Diabetic Peripheral Neuropathy, Sarcopenia
- Trial name
- SVT-DNP (NCT06519942)
- Testing
- Blood sampling, Electromyoneurography (EMNG), Muscle biopsy
- Where
- Belgium
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Diabetic Polyneuropathy
Efficacy and Safety Study of Topical Capsaicin in Painful Diabetic Neuropathy
Painful diabetic neuropathy is the most common cause of neuropathic pain. 0.075% topical capsaicin has been used to treat the pain, but there is no data in lower concentration.
- Trial name
- NCT00993070
- Testing
- Capsaicin
- Where
- Thailand
- Volunteers
- 33 people
- Sponsor
- Thammasat University
Diabetic Peripheral Neuropathy
Safety and Efficacy of CBX129801 in Patients With Type 1 Diabetes
The purpose of the study is to determine the beneficial effects of CBX129801 (PEGylated synthetic human C-peptide) following weekly subcutaneous administration for 12 months in type 1 diabetes mellitus patients (T1DM) with mild…
- Trial name
- NCT01681290
- Testing
- CBX129801
- Where
- 29 sites in United States, Canada and 1 more
- Volunteers
- 250 people
- Sponsor
- Cebix Incorporated
Diabetic Foot Ulcer, Diabetic Neuropathy Peripheral
Patients With Diabetic Neuropathy Who Receive Physiotherapy Treatment Will Have a Decrease in Diabetic Foot Ulcers
This study evaluates the effects of a physiotherapy protocol (manual therapy and exercise) in the prevention of diabetic foot ulcers in patients with diabetic neuropathy.
- Trial name
- NCT03725917
- Testing
- Physiotherapy protocol
- Where
- Spain
- Volunteers
- 143 people
- Sponsor
- Universidad Complutense de Madrid
Diabetic Foot Ulcer
3C Patch® Medicare Claims Study
This prospective study will compare incidence rates of complete hard-to-heal diabetic foot ulcer healing in Medicare beneficiaries following application of the 3C Patch® plus usual care, tested against a historical control group…
- Trial name
- NCT03997526
- Testing
- 3C Patch
- Where
- 6 sites in United States
- Volunteers
- 22 people
- Sponsor
- Reapplix
Diabetic Foot Ulcer
A Phase 3 Clinical Trial to Assess the Effectiveness of BioChaperone PDGF-BB In the Treatment of Chronic Diabetic Foot Ulcer
The present clinical trial is designed to assess the effectiveness of BioChaperone PDGF-BB applied at 4 µg/cm² every other day for up to 20 weeks and associated to Standard of Care as compared to Standard of Care alone for the…
- Trial name
- NCT02236793
- Testing
- BioChaperone PDGF-BB, Standard of Care
- Where
- 32 sites in India
- Volunteers
- 252 people
- Sponsor
- Adocia
Diabetes Mellitus, Diabetic Foot Ulcer
Online Diabetic Foot Support Program- Care Kit
The aim of this project is to examine the effects of the online diabetic foot support program (DiaFootSuP) and care kit applied to type 2 diabetic individuals who have previously had a diabetic foot ulcer on diabetic foot…
- Conditions
- Diabetes Mellitus, Diabetic Foot Ulcer, Diabetic Foot
- Trial name
- DiaFootSuP (NCT06760416)
- Testing
- Nursing Education
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Merve GÃnbaAY
Diabetic Foot Ulcer, Vitamin D Deficiency
High-Dose Vitamin D3 for Diabetic Foot Ulcer Healing: Randomized Controlled Trial
This randomized, double-blind, placebo-controlled clinical trial aims to evaluate the effectiveness of high-dose vitamin D3 supplementation in improving diabetic foot ulcer (DFU) healing.
- Conditions
- Diabetic Foot Ulcer, Vitamin D Deficiency, Wound Healing Disorder
- Trial name
- DFU (NCT07139964)
- Testing
- Vitamin D3
- Where
- Indonesia
- Volunteers
- 24 people
- Sponsor
- Universitas Sriwijaya
Diabetic Foot Ulcer of Neuropathic Origin
The TRAfermin in Neuropathic Diabetic Foot Ulcer Study - Southern Europe The TRANS-South Study
Trafermin is a recombinant human basic fibroblast growth factor (bFGF; original development code, KCB-1), which is manufactured by genetic engineering using Escherichia coli by Kaken Pharmaceutical Co., Ltd. (Tokyo, Japan).
- Trial name
- TRANS-South (NCT01217463)
- Testing
- Trafermin 0.01% spray
- Where
- 24 sites in Czechia, France and 2 more
- Volunteers
- 201 people
- Sponsor
- Olympus Biotech Corporation
Chronic Limb-Threatening Ischemia, Diabetic Foot
Observational Study Regarding the Necessity of Inclusion of Foot Arch State Together With the Angiosome Theory Within the Wound, Ischemia and Foot Infection Classification (WIfI) to Enhance the Predictability of Wound Healing and Decision Making
This study aims to assess the complete healing or healing progress of foot ulcer within 1 year Where the patients will be classified according to foot arch state together with the angiosome theory and the WIFI clinical stage to…
- Conditions
- Chronic Limb-Threatening Ischemia, Diabetic Foot, Vascular Diseases
- Trial name
- NCT06542523
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Diabetic Neuropathy
Effects of a Homeopathic Anti-inflammatory Topical Cream on Ulcers and Neuropathy in the Diabetic Foot
This is a study whose primary objective is to assess the effectiveness of Neuropathy/Ulcer Cream in the promotion of healing skin fissures plantar foot ulcers and as a moisturizer to prevent dry skin turning into ulcers as…
- Trial name
- NCT01951859
- Testing
- Neuropathy/Ulcer Homeopathic topical cream
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Calvary Hospital, Bronx, NY
Diabetic Foot Ulcer
CO2-Laser Treatment in Patients With Diabetic Infected Foot Ulcers
The study is aimed at comparing debridement either with CO2 laser or traditional surgery in patients with infected diabetic foot ulcers. The principal endpoint is bacterial load immediately after treatment.
- Trial name
- DULCIS (NCT02677779)
- Testing
- CO2 laser, traditional surgery
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Diabetic Foot
Effect of Subtalar and Talocrural Joint Mobilization on Foot Ranges and Posture in Diabetic Patients
The aim of this research is to determine the Effects of mobilizations on foot ranges and posture in people with Type 2 Diabetes Mellitus. Randomized controlled trials will be done at Dr.
- Trial name
- NCT05922280
- Testing
- subtalar and talo-crural mobilization, International Working Group of the Diabetic Foot care guidelines
- Where
- Pakistan
- Volunteers
- 41 people
- Sponsor
- Riphah International University
Diabetic Foot
Study on Regeneration of Skin Defects in Diabetic Ulcers Treated With New Electrospun Material PLCL/Fg
Prospective cohort studies through clinical trials. Obtained a large amount of real-world data to explore the efficacy of PLCL/Fg dressings for specific clinical applications. Published 1 relevant SCIE paper.
- Trial name
- NCT06014437
- Testing
- PLCL/Fg group, control group
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Guili Wang
Myocardial Infarction, Diabetes Mellitus, Type 2
Aerobic Training in Post-MI Patients With DPN
Cardiac rehabilitation (CR) is categorized by the American College of Cardiology "class IA recommendation" in the management of patients with cardiovascular disease (CVD) including post-myocardial infarction (MI) patients, who…
- Conditions
- Myocardial Infarction, Diabetes Mellitus, Type 2, Diabetic Peripheral Neuropathy
- Trial name
- NCT03913793
- Testing
- Exercise based-cardiac rehabilitation (EB-CR) program
- Volunteers
- 37 people
- Sponsor
- Yousra Hisham Abdel Fattah
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