Clinical trials: Neuropathy, Diabetic
Chronic Pain
Study to Evaluate the Long-Term Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) in Patients Who Require Opioid Treatment for an Extended Period of Time
The primary objective of this study is to evaluate the safety of hydrocodone extended-release tablets when used over a 12-month period in patients with chronic pain, as assessed by adverse events, clinical laboratory results…
- Trial name
- NCT01223365
- Testing
- Hydrocodone ER
- Where
- 54 sites in United States
- Volunteers
- 330 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Diabetic Foot Ulcers
Effectiveness of dermaPACE™ Device and Standard Treatment Compared to Standard Treatment Alone for Diabetic Foot Ulcers
The purpose of this study is to compare the safety and effectiveness of the dermaPACE Device to sham application, when administered in conjunction with standard treatments used in the treatment of DFUs.
- Trial name
- NCT00536744
- Testing
- acoustical pulse energy (extracorporeal shockwave)
- Where
- 23 sites in United States, Germany and 1 more
- Volunteers
- 206 people
- Sponsor
- SANUWAVE, Inc.
Diabetes, Diabetic Foot
Foot Assessment in People With Diabetes: A Quantitative Diagnostic Approach
This observational cohort study aims to develop a novel risk stratification system implementing biomechanics to aid in the prevention of diabetic foot ulcers.
- Conditions
- Diabetes, Diabetic Foot, Diabetes Complications, Diabetes; Neuropathic (Manifestation)
- Trial name
- NCT03089463
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 153 people
- Sponsor
- Staffordshire University
Diabetic Foot Ulcer, Diabetic Angiopathies
Remote Ischemic Conditioning and Diabetic Foot Ulcers
Study type: Randomized, double blinded, interventional, single-site study. Two groups: Active receiving RIC therapy from the LifeCuff device and standard of care treatment without RIC.
- Trial name
- NCT04567563
- Testing
- Remote Ischemic conditioning (RIC)
- Volunteers
- 50 people
- Sponsor
- Des Moines University
Peripheral Vascular Disease, Diabetic Foot
Autologous Bone Marrow Stem Cell Transplantation for Critical, Limb-threatening Ischemia
Critical limb ischemia is a condition where the blood circulation in the limbs, in most cases the legs, is decreased so that pain and non healing wounds ensue. Mostly, this is a sequel of arteriosclerosis and/or diabetes.
- Conditions
- Peripheral Vascular Disease, Diabetic Foot, Peripheral Arterial Occlusive Disease, Leg Ulcer
- Trial name
- BONMOT (NCT00434616)
- Testing
- Autologous bone marrow cell concentrate transplantation, saline injection
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Franziskus-Krankenhaus
Diabetic Retinopathy
Long-term Retinal Changes After Topical Citicoline Administration in Patients With Mild Signs of Diabetic Retinopathy in Type 1 Diabetes Mellitus.
Citicoline (cytidine-5'-diphosphocholine) is an essential precursor in the synthesis of phosphatidylcholine, a component of cell membranes.
- Trial name
- NCT04009980
- Testing
- OMK2 group
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione G.B. Bietti, IRCCS
Type 2 Diabetes Mellitus, Diabetic Foot
Register for Patients With Diabetic Foot Syndrome and Critical Limb Ischemia
Diabetic foot syndrome (DFS) is a disease caused by neurogenic (concerning the nervous system), vascular, mechanic and metabolic factors, which are further complicated by an impairment of the immune system and a corresponding…
- Conditions
- Type 2 Diabetes Mellitus, Diabetic Foot, Critical Limb Ischemia
- Trial name
- August-1 (NCT01599442)
- Where
- Germany
- Volunteers
- 123 people
- Sponsor
- GWT-TUD GmbH
Diabetic Foot Ulcer, Pressure Ulcer
A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in Elderly Population in Specialized Nursing Facilities Using RD1
The study is a prospective, single arm, multicenter efficacy study, consisting of 60 subjects who will complete the study (note: if any patients are lost to follow-up or withdrawn, enrollment will increase to compensate for loss…
- Conditions
- Diabetic Foot Ulcer, Pressure Ulcer, Venous Leg Ulcer, Trauma Injury
- Trial name
- NCT04577183
- Testing
- RD1 System
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- RedDress Ltd.
Diabetic Foot Ulcer
Low-level Laser Therapy for the Treatment of Diabetic Foot Ulcer
The study evaluates the efficacy of Low-level laser therapy on ulcer healing in patients with diabetic foot ulcer. Half the patients are randomized to receive Low-level laser therapy and a half to recieve the placebo (LED).
- Trial name
- NCT03788642
- Testing
- Control LED shoe arm, Laser Shoe arm
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Mahidol University
Neuropathy, Small Fiber, Diabete Mellitus
Effect of Tirzepatide on Diabetic Peripheral Sensorimotor Neuropathy
Tirzepatide is a dual agonist of GLP-1 Receptor and the GIP receptor, producing substantial improvement in glycaemic control, weight reduction and insulin sensitivity.
- Trial name
- T-DPN (NCT07706088)
- Testing
- Tirzepatide 2.5mg weekly, all standard of care to diabetic patient besides tirzepatide
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Diabetic Neuropathy, Painful
Safety and Efficacy of AGN 203818 in Patients With Painful Diabetic Peripheral Neuropathy
This study will explore the safety and effectiveness of different doses of AGN 203818 in treating pain in patients with painful diabetic peripheral neuropathy
- Trial name
- NCT00381719
- Testing
- AGN 203818
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Allergan
Diabetic Foot Ulcer, Healing Delayed
Mean Healing Time of Wound After Vacuum Assisted Closure (VAC) Versus Conventional Dressing in Diabetic Foot Ulcer Patients
Comparison the mean healing time of wound after vacuum assisted closure(VAC) versus conventional dressing(CD) in diabetic foot ulcer(DFU) patients.
- Conditions
- Diabetic Foot Ulcer, Healing Delayed, Wound; Foot, Diabetes Mellitus
- Trial name
- NCT04959071
- Testing
- Vacuum assisted closure VAC vs conventional dressing
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Bahria University
Foot Ulcer, Diabetic
A Comparison of an Investigational Dressing to Tegaderm Matrix Wound Dressing in the Management of Diabetic Foot Ulcers
The primary objective is to: Assess the effect of the Non-adherent study dressing to 3M Tegaderm Matrix Dressing with PHI technology on wound healing in patients with a diabetic foot ulcer.
- Trial name
- NCT01013792
- Testing
- Wound Dressing
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- Solventum US LLC
Type 2 Diabetes Mellitus, Diabetic Neuropathy
GlucoBites Cookies (Gynura Procumbens) for Glycemic Control and Prevention of Diabetic Foot Ulcer Risk in Type 2 Diabetes
The goal of this randomized controlled trial is to learn if GlucoBites functional cookies containing Gynura procumbens can help improve blood sugar control and lower the risk of diabetic foot ulcers in adults with type 2…
- Trial name
- GlucoBites (NCT07151833)
- Testing
- GlucoBites (with Gynura procumbens), Control Cookies (without Gynura procumbens)
- Where
- Indonesia
- Volunteers
- 126 people
- Sponsor
- Andina Setyawati
Diabetic Peripheral Neuropathy, Painful Diabetic Neuropathy
Microvascular Dysfunction in Diabetic Peripheral Neuropathy
This study primarily seeks to evaluate dysfunction of small blood vessels and their linkage to dysfunction of nerves in people with Type 2 Diabetes.
- Trial name
- NCT05118217
- Testing
- This is a non-interventional study
- Volunteers
- 72 people
- Sponsor
- University of Plymouth
Diabetic Foot, Therapeutics
Clinical Observation and Mechanism Study of Yunnan Baiyao in Different Stages of Diabetic Foot
Yunnan Baiyao has been treating all kinds of wounds for 120 years, but the evidence of Evidence-based medicine that is truly convincing is insufficient, making its best application method unclear.
- Trial name
- NCT06062576
- Testing
- Yunnan Baiyao
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Chronic Kidney Disease Stage 3 and 4, Diabetes
Prediction of Peripheral Neuropathy With Functional Testing
Diabetes and chronic kidney disease (CKD) are two distinct pathologies. The former is defined as an impairment in insulin production and/or utilization, while the latter refers to structural or functional abnormalities of the…
- Trial name
- PredictNP (NCT06933108)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Université catholique de l'Ouest
Diabetic Foot, Quality of Life
Patient Empowerment Study
The Patient Empowerment Study is an observational longitudinal study among adults with diabetic foot ulcer (DFU). The scope of this study is to better understand how a patient's DFU disease process and usage of the Podimetrics…
- Conditions
- Diabetic Foot, Quality of Life, Mental Health Wellness 1, Ulcer Foot
- Trial name
- NCT04537676
- Testing
- No intervention, this is an observational study
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Podimetrics, Inc.
Diabetes Mellitus, Neuropathy, Diabetic
Assessments and Interventions for Hand Neuropathy in DM
This study is to investigate the effects of task-based biofeedback training compared with home-based programs on sensorimotor function and quality of life for diabetic patients with neuropathic hands.
- Trial name
- NCT03847129
- Testing
- Biofeedback training, Home-based tendon gliding and resistance training
- Where
- Taiwan
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Diabetic Foot Infection, Osteomyelitis
A Clinical Trial Testing the Efficacy of PDT in Preventing Amputation in Diabetic Patients
The feet of diabetic patients continue to be an important problem in medicine. In general, patients with diabetic foot have some sort of amputation, especially in underserved populations.
- Conditions
- Diabetic Foot Infection, Osteomyelitis, Photo Antimicrobial Chemotherapy
- Trial name
- NCT03380403
- Testing
- PDT, Ciprofloxacin
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Faculdade de Medicina do ABC
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.