Clinical trials: Neuropathy, Diabetic
Rheumatoid Arthritis, Diabetic Neuropathy
Basket Study (CT-100-002) to Evaluate the Effects of a DiNaMo™ Component Training
CT-100 is a platform that provides interactive, software based therapeutic components that may be used as part of a multimodal treatment in supplementary or standalone prescription or nonprescription software-based digital…
- Conditions
- Rheumatoid Arthritis, Diabetic Neuropathy, Fibromyalgia, Irritable Bowel Syndrome
- Trial name
- NCT05573685
- Testing
- DiNaMo Study App
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Click Therapeutics, Inc.
Painful Diabetic Neuropathy, Diabetes Mellitus
A 12-Week Study of Topical Pirenzepine or Placebo in Type 2 Diabetic Patients (T2DM) With Painful Peripheral Neuropathy
This is a 12 week, 2-arm, blinded, single-site, placebo-controlled Phase II study in subjects with Type II Diabetes and painful peripheral neuropathy.
- Trial name
- NCT04786340
- Testing
- Active: WST-057 4mL (146 mg pirenzepine free base monohydrate) topical solution
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- WinSanTor, Inc
Peripheral Vascular Diseases, Diabetic Foot
Autologous Bone Marrow Derived Mononuclear Cells in Treating Diabetic Patients With Critical Limb Ischemia
The aim of this study is to assess the efficacy and safety of autologous transplantation of bone-marrow cells for therapeutic angiogenesis and vasculogenesis in diabetic patients with non-revascularizable critical limb ischemia.
- Trial name
- NCT00872326
- Testing
- Autologous Bone Marrow Mononuclear Cells
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Andalusian Network for Design and Translation of Advanced Therapies
Diabetic Polyneuropathy
Effect of Feldenkrais Method in Enhancing Postural Control for Patients with Diabetic Polyneuropathy
Background: Postural Control is a major complication of polyneuropathy, affecting patients suffering from diabetes mellitus. Purpose: To examine the effect of the Feldenkrais Method on dynamic balance, limits of stability and…
- Trial name
- FeM (NCT06904417)
- Testing
- The Feldenkrais-based intervention, conventional balance training program
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Diabetic Foot Ulcer (DFU), Ulcer
Evaluating Autologous Platelet-Rich Fibrin Plasma for Chronic Diabetic Foot Ulcers
To prospectively evaluate the safety and efficacy of an Autologous Platelet-Rich Fibrin Plasma system when applied in conjunction with Standard of Care for management of chronic Diabetic Foot Ulcers.
- Conditions
- Diabetic Foot Ulcer (DFU), Ulcer, Wound Closure, Wound Management
- Trial name
- NCT07840378
- Testing
- PRFM, Standard of Care (SoC)
- Volunteers
- 55 people
- Sponsor
- Tiger Biosciences, LLC.
Diabetic Neuropathies
Randomized, Double-blind Study to Assess the Efficacy and Safety of α-lipoic Acid Versus BK-C-0701 in Subjects With Diabetic Neuropathy
The purpose of this study is to determine the: Primary end point change of Total symptom score Secondary end point neurological test
- Trial name
- NCT01261143
- Testing
- BK-C-0701
- Where
- South Korea
- Volunteers
- 164 people
- Sponsor
- Bukwang Pharmaceutical
Diabetic Peripheral Neuropathic Pain
Evaluation of the Long-term Safety and Effectiveness of Suzetrigine (SUZ) in Participants With Painful Diabetic Peripheral Neuropathy (DPN)
The purpose of this study is to evaluate the long-term safety and tolerability of SUZ and long-term effectiveness of SUZ in treating pain associated with DPN.
- Trial name
- NCT06696443
- Testing
- Suzetrigine
- Where
- 65 sites in United States
- Volunteers
- 455 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Diabetic Polyneuropathy, Diabetic Foot
The Effect of Mini Trampoline Exercise Program on Diabetic Foot Care Behavior and Polyneuropathy
This study was planned to examine the effect of home-based mini trampoline exercise program on diabetic foot care behavior and diabetic polyneuropathy in Type 2 diabetes patients.
- Conditions
- Diabetic Polyneuropathy, Diabetic Foot, Type 2 Diabetes
- Trial name
- NCT05668325
- Testing
- Mini trampoline exercise group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Diabetic Foot Ulcers
MSI-78 Topical Cream vs. Oral Ofloxacin in the Treatment of Infected Diabetic Ulcers
224 adults with diabetic foot ulcers will be randomized to either magainin peptide (MSI-78) or ofloxacin (FLOXIN, Ortho-McNeil Pharmaceutical Corporation) an oral fluoroquinolone antibiotic.
- Trial name
- NCT00563433
- Testing
- ofloxacin, MSI-78
- Where
- United States
- Volunteers
- 342 people
- Sponsor
- Abeona Therapeutics, Inc
Wound Healing
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Single and Repeated Doses of Topical GSK1278863
This is a randomized, placebo-controlled, single-blind (subjects and investigators will be blinded, GSK internal personnel will not be blinded), parallel-group, two part (Part A, Part B) trial in healthy volunteers and subjects…
- Trial name
- NCT01831804
- Testing
- GSK1278863
- Where
- 7 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Diabetic Cardiovascular Autonomic Neuropathy, Type 2 Diabetes Mellitus
Acupuncture Plus Mecobalamin for Diabetic Cardiac Autonomic Neuropathy
The goal of this clinical trial is to learn whether acupuncture can improve damage to the nerves that control the heart (cardiac autonomic neuropathy) in adults with type 2 diabetes.
- Conditions
- Diabetic Cardiovascular Autonomic Neuropathy, Type 2 Diabetes Mellitus, Diabetic Neuropathies
- Trial name
- NCT07907536
- Testing
- Acupuncture, Mecobalamin
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Diabetic Foot Ulcer, Diabetic Foot Infection
Randomized Double-Blind Trial on Safety and Efficacy of Nanordica Advanced Antibacterial Wound Dressing for Diabetic Foot Ulcer
This clinical trial evaluates the safety and efficacy of the Nanordica Advanced Antibacterial Wound Dressing (AAWD) in patients suffering from diabetic foot ulcers.
- Trial name
- NM2023 (NCT06667752)
- Testing
- Advanced Antibacterial Wound Dressing, Aquacel Ag+ Extra
- Where
- 11 sites in Estonia, Spain
- Volunteers
- 136 people
- Sponsor
- Nanordica Medical OU
Diabetic Foot Ulcer
Proof of Concept Open Label, Clinical Trial to Evaluate the Safety and Efficacy of the "FITT" Device in Diabetic Foot Ulcers Patients
The TriO FITT device is designed to improve the symptoms of chronic diabetic ulcers. The mechanism of action of the device optimizes and combines the administration known supproting treatments to chronic diabetic ulcers.
- Trial name
- TriO FITT (NCT06003400)
- Testing
- Study treatment administration (TriO FITT), Physical Examination, Vital Signs
- Where
- Israel
- Volunteers
- 19 people
- Sponsor
- Tri.O Medical LTD
Diabetes Mellitus, Type 2, Neuropathic Pain
Effect of a Combined Exercise Program on Neuropathic Pain and Perceived Quality of Life in Type 2 Diabetes
Therapeutic exercise is one of the therapies used as a treatment for diabetic neuropathy, which is a complication of diabetes. In order to reduce pain and improve the perception of quality of life, a combined therapeutic exercise…
- Conditions
- Diabetes Mellitus, Type 2, Neuropathic Pain, Neuropathy, Diabetic
- Trial name
- NCT05703152
- Testing
- Combined Exercise
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- Maria Gabriela Aké Palomo
Painful Diabetic Neuropathy
Efficacy and Safety of MEDI7352 in Participants With Painful Diabetic Neuropathy
This is a study investigating the effect of MEDI7352 on chronic pain in participants with painful diabetic neuropathy. The study incudes a screening period of up to 45 days and a 12-week treatment period during which MEDI7352 or…
- Trial name
- NCT03755934
- Testing
- MEDI7352
- Where
- 31 sites in Denmark, Hungary and 3 more
- Volunteers
- 112 people
- Sponsor
- AstraZeneca
Diabetic Foot
Wound Bed Preparation for Diabetic Foot Ulcers
The study objective was to compare the efficacy of NPWT versus alginates dressings on the wound bed preparation prior to STSG surgery, as well as investigating the underlying mechanisms.
- Trial name
- NCT05577104
- Testing
- Negative pressure wound therapy (NPWT), conventional moist dressings
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Pressure Ulcer, Diabetic Foot Ulcer
The Study of Wound Dressings for Portable NPWT
Introduction Negative pressure wound therapy (NPWT), also known as topical negative pressure, has become a popular therapy for the treatment of many acute and chronic wounds.
- Trial name
- NPWT (NCT03135964)
- Testing
- filler dressing of NPWT
- Where
- Taiwan
- Volunteers
- 57 people
- Sponsor
- Tainan Municipal Hospital
Diabetic Peripheral Neuropathy
Laser Therapy for Diabetic Peripheral Neuropathic Pain
The proposed study is a randomized, double-blinded clinical trial to evaluate the efficacy of a course of laser therapy on peripheral neuropathic pain in persons with diabetes.
- Trial name
- NCT02328911
- Testing
- Laser treatment
- Where
- United States
- Sponsor
- University of Miami
Diabetic Peripheral Neuropathy
Effect of Rotating Magnetic Therapy on Diabetic Peripheral Neuropathy
The aim of the study is to assess the effect of Rotating Magnetic Therapy on Diabetic Peripheral Neuropathy using Nerve conduction velocity examination.
- Trial name
- NCT03983200
- Testing
- Rotating Magnetic Therapy, Mecobalamin
- Volunteers
- 200 people
- Sponsor
- Majianhua
Diabetic Foot Ulcers
Phase 3 Study Evaluating Efficacy and Safety of DSC127 Compared With Vehicle and With Standard-of-care in Diabetic Foot Ulcers
To determine if aclerastide (DSC127) is effective in increasing incidence of complete wound closure up to 10 weeks confirmed 2 weeks later, compared with vehicle (gel without active ingredient) and compared with a…
- Trial name
- STRIDE 2 (NCT01849965)
- Testing
- DSC127, Standard of Care gel, Aquasite
- Where
- 56 sites in United States, Canada and 2 more
- Volunteers
- 396 people
- Sponsor
- Integra LifeSciences Corporation
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