Clinical trials: Neuropathy, Diabetic
Diabetic Foot Ulcer (DFU), Orthoses
The Effect of Using Insoles Specially Designed for Diabetic Foot on Postural Balance and Gait Parameters
Postural control and plantar pressure are affected by many parameters in diabetic individuals. It is considered important to examine the relationship between changes in plantar pressure distribution and postural balance…
- Conditions
- Diabetic Foot Ulcer (DFU), Orthoses, Postural Balance, Plantar Pressure Distrubution
- Trial name
- NCT06846476
- Testing
- Insole, Demographic Information and Anamnesis Form, Pedobarographic analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Medipol University
Chronic Wounds, Venous Leg Ulcer (VLU)
Evaluation of Cold Plasma in Chronic Wound Healing
The goal of this clinical trial is to evaluate the effectiveness of cold atmospheric plasma treatment in promoting the healing of chronic wounds in adult participants suffering from chronic wounds.
- Conditions
- Chronic Wounds, Venous Leg Ulcer (VLU), Diabetic Foot Ulcer (DFU), Pressure Ulcer (PU)
- Trial name
- PLASANAGENESIS (NCT06964048)
- Testing
- Cold Atmospheric Plasma treatment
- Volunteers
- 66 people
- Sponsor
- Plasana Medical
Diabetic Foot Ulcer, Infection
Topical PluroGel N for the Treatment of Mildly Infected Diabetic Foot Ulcers
This will be a randomized, double-blind (evaluator-blind), vehicle-controlled study of 50 enrolled subjects. Adult subjects (greater than 18 years old) who present with a mildly infected diabetic foot ulcer (IDSA criteria) having…
- Trial name
- NCT02091596
- Testing
- PluroGel N, PluroGel
- Where
- 15 sites in United States
- Volunteers
- 42 people
- Sponsor
- PluroGen Therapeutics, Inc
Neuromuscular Transmission Disorder, Diabetes Mellitus, Type 2
Effect of Type II Diabetes Mellitus With Neuropathy on the Clinical Use of Rocuronium
International Diabetes Federation estimates that there are now 415 million adults aged 20-79 with diabetes mellitus worldwide. By 2040 this will rise to 640 million.
- Trial name
- NCT03737942
- Testing
- monitoring of neuromuscular function
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Diabetic Neuropathic Pain
the Effectiveness of Intermittent Pneumatic Compression on Neuropathic Pain in Patients With Diabetic Polyneuropathy
In this study,the effectiveness of intermittent pneumatic compression therapy on neuropathic pain and quality of life in patients with neuropathic pain due to type 2 diabetes was investigated
- Trial name
- NCT06336486
- Testing
- intermittent pneumatic compression +pregabalin group, pregabalin group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Busra Gunes
Diabetes Mellitus, Foot Ulcer
REOXCARE Dressing to Improve Healing in Diabetic Foot Ulcers (DFU)
It has been shown that diabetic patients present a significant increase in markers related to oxidative stress, which increases even more in those with diabetic foot ulcers and gradually depending on the severity of the injury…
- Conditions
- Diabetes Mellitus, Foot Ulcer, Neuroischemic Foot Ulcer
- Trial name
- REOXDFU (NCT05413746)
- Testing
- Reoxcare antioxidant dressing
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Histocell, S.L.
Peripheral Neuropathy, Diabetic Neuropathies
Efficacy of Moxibustion in Diabetes Peripheral Neuropathy
This pragmatic randomized controlled study aimed to evaluate the effectiveness and safety of moxibustion therapy on diabetes peripheral neuropathy.
- Trial name
- NCT04894461
- Testing
- Moxibustion
- Volunteers
- 40 people
- Sponsor
- Xiamen University
Diabetic Peripheral Neuropathy, Entrapment Neuropathy
Ultrasound-Guided Nerve Hydrodissection for Diabetic Lower Limb Entrapment Neuropathy
The goal of this clinical trial is to learn if a single session of ultrasound-guided nerve hydrodissection can relieve symptoms of diabetic lower limb entrapment neuropathy, a condition caused by compressed nerves in the leg that…
- Trial name
- HUND (NCT07625020)
- Testing
- Ultrasound-guided nerve hydrodissection treatment
- Where
- China
- Volunteers
- 266 people
- Sponsor
- Chongqing Medical University
Diabetic Foot Ulcers
Clinical Efficacy of Platelet Gel From Cord Blood for the Treatment of Diabetic Foot Ulcers
A novel method (PCT n. WO 2010/007502 A2, 2010) has been developed to obtain platelet gel from umbilical cord blood (CBPG). The main advantages so far identified in CBPG as compared to platelet gel derived from adult platelets…
- Trial name
- CBPG-DFU (NCT02389010)
- Testing
- Allogeneic cord blood platelet gel-CBPG, Standard Local Medications-SLM
- Where
- 9 sites in Italy, Spain
- Volunteers
- 50 people
- Sponsor
- Centro Nazionale Sangue
Pain, Diabetic Neuropathy
A Study of Sativex® for Pain Relief Due to Diabetic Neuropathy
The purpose of this study is to evaluate the efficacy of Sativex® compared with placebo in relieving pain due to Diabetic Neuropathy.
- Trial name
- NCT00710424
- Testing
- Sativex
- Where
- United Kingdom
- Volunteers
- 297 people
- Sponsor
- Jazz Pharmaceuticals
Diabetic Foot Ulcer (DFU), Diabetic Foot Ulcer Treatment
CHEMfoot: DEBRICHEM® in Chronic Diabetic Foot Wounds
This multicenter, randomized controlled trial will evaluate the effectiveness and safety of DEBRICHEM®, a topical desiccant gel, when added to standard care for chronic diabetic foot wounds.
- Conditions
- Diabetic Foot Ulcer (DFU), Diabetic Foot Ulcer Treatment, Diabetic Foot Wounds
- Trial name
- CHEMfoot (NCT07206862)
- Testing
- DEBRICHEM®
- Volunteers
- 242 people
- Sponsor
- DEBx Medical B.V.
Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU)
A Non-Randomized Open Label Clinical Trial Evaluating DermaBind TL
The purpose of this clinical evaluation is to collect patient outcome data and evaluate the efficacy, safety and tolerability of HealthTech DermaBind TL™ in patients with chronic non-healing wounds in patients with chronic…
- Trial name
- NCT07172893
- Testing
- DermaBind TL
- Where
- 10 sites in United States
- Volunteers
- 150 people
- Sponsor
- HealthTech Wound Care
Retinal Neuropathy, Neurodegeneration
Retinal Neurodegeneration In Type 2 Diabetes Mellitus Detected by Optical Coherence Tomography
Evaluation of retinal neurodegeneration in patients with type 2 diabetes mellitus (DM2) without diabetic retinopathy or with mild non proliferative diabetic retinopathy
- Trial name
- NCT04808804
- Testing
- Optical Coherence Tomography (OCT)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Open Cracked Heel in Diabetic Patients With Polyneuropathy
Efficacy and Safety of V0111 Cream on Open Cracked Heel in Diabetic Patients With Polyneuropathy.
The purpose of this study is to evaluate the efficacy and the safety of the cream V0111 in the treatment of fissure(s) situated on the heels in diabetic patients with polyneuropathy.
- Trial name
- NCT02045199
- Testing
- Tested product : V0111 cream
- Where
- 20 sites in Belgium, France
- Volunteers
- 193 people
- Sponsor
- Pierre Fabre Medicament
Diabetic Neuropathy
Clinical Outcomes Related to Treatment of Distal Symmetric Polyneuropathy Using Semiconductor Embedded Therapeutic Socks
Distal symmetric polyneuropathy, also known as diabetic neuropathy, is the most common neurological complication of diabetes and a main cause of morbidity.
- Trial name
- NCT06452914
- Testing
- Semiconductor Embedded Therapeutic Socks
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Endocrine Research Solutions
Diabetic Foot Ulcer
The Effect of Exercise on Wound Healing While Off-loading
This study seeks to establish the effect of adding exercise to off-loading interventions on the healing time for people with diabetes mellitus and a foot ulcer.
- Trial name
- NCT04280016
- Testing
- Exercise
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mercer University
Diabetic Foot
Smart Diabetic Foot Care Application
This study developed an app for the guidance of home-based diabetic foot care to explore its impact on patients' foot assessment awareness and self-care behavior after using this app.
- Trial name
- NTUNHS (NCT06844955)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Clinical Trial of SB-509 in Subjects With Diabetic Neuropathy
The purpose of the study is to study the clinical effects of the investigational drug, SB-509 versus placebo in patients with diabetic neuropathy.
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetic Polyneuropathy
- Trial name
- NCT00406458
- Testing
- SB-509, Normal Saline
- Where
- 15 sites in United States, Mexico
- Volunteers
- 110 people
- Sponsor
- Sangamo Therapeutics
Diabetic Neuropathy
An Open Label, Dose Finding Trial of Viagra for the Treatment of Neuropathic Pain (in Diabetes Mellitus)
The purpose of this study is to study if sildenafil (Viagra) is effective in improving neuropathic pain. This will be an open label study at 3 doses of sildenafil (25 mg, 50 mg and 100 mg).
- Trial name
- NCT00194909
- Testing
- sildenafil (Viagra)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Weill Medical College of Cornell University
Diabetic Foot
A Study on Predictive Model for New-onset Diabetic Foot in Type 2 Diabetes Patients.
A retrospective cohort study was constructed based on hospitalized patients with type 2 diabetes, aiming to explore the related factors for new-onset diabetic foot and conducted a robust prediction model by Cox proportional…
- Trial name
- NCT05519163
- Where
- China
- Volunteers
- 6,301 people
- Sponsor
- Yibing Wang
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