Clinical trials: Neuropathy, Diabetic
Diabetic Peripheral Neuropathy
Effect of High Tone External Muscle Stimulation on Peripheral Arterial Disease
to investigate the effect of high tone external muscle stimulation (HTEMS) on endothelial dysfunction and walking parameters in peripheral vascular disease.
- Trial name
- NCT04555876
- Testing
- high tone external muscle stimulation- stationary bicycle
- Volunteers
- 60 people
- Sponsor
- Cairo University
DIABETIC FOOT ULCERS
Study of Maggot Therapy in Diabetic Foot Ulcers
This study was a Kind of clinical trial with equal randomization, that have been done from January 2009 to June 2011 in the AFZALIPOOR hospital endocrine ward in Kerman-Iran on 128 diabetic patient who had foot wounds.Replacement…
- Trial name
- MDT (NCT01681160)
- Testing
- procedure:maggot therapy, conventional therapy
- Volunteers
- 128 people
- Sponsor
- Kerman Medical University
Diabetes Mellitus, Diabetic Neuropathy
Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients
This prospective observational study aims to evaluate the effects of ultrasound-guided ankle block on sensory and motor block characteristics and postoperative analgesic outcomes in patients undergoing lower extremity surgery.
- Conditions
- Diabetes Mellitus, Diabetic Neuropathy, Postoperative Pain Management
- Trial name
- ANKLE-DM (NCT07404124)
- Testing
- Ultrasound-Guided Ankle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Diabetic Foot Ulcers
Omeza Products in Combination With Standard of Care for the Treatment of Diabetic Foot Ulcers
This study is to evaluate the efficacy of OCM™ used in combination with off-loading devices for the treatment of diabetic foot ulcers.
- Trial name
- NCT05417425
- Testing
- Omeza collagen matrix, Omeza lidocaine lavage, Omeza skin protectant
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Omeza, LLC
Diabetic Foot Ulcer
Vibration Enhances Diabetic ULCER Healing
Objectives: Diabetes has a prevalence of 11.6% in China with diabetic foot ulcerations affecting over 30 million Chinese. 85% of these patients require amputation and 5-year mortality for diabetics is 70% when associated foot…
- Trial name
- VIBEDULCER (NCT04275804)
- Testing
- Low Magnitude High Frequence Vibration Platform, Conventional Dressing
- Volunteers
- 106 people
- Sponsor
- Chinese University of Hong Kong
Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU)
Evaluation of the Safety and Efficacy of Dehydrated Human Placenta Tissue (dHPT) for Wound Healing
The retrospective trial is observational, intended to stand alone, complement and integrate data collected in ongoing clinical studies to aid in establishing payor coverage in the United States (U.S.) for Cellution Biologics…
- Conditions
- Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU), Pressure Ulcer (PU)
- Trial name
- RETRO-PLAST (NCT07375160)
- Testing
- dHPT, AIC
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Cellution Biologics
Diabetic Foot Ulcer
Intermittent Negative Pressure for Patients With Diabetic Foot Ulcers (INPRESS) Study
The aim of this trial is to investigate the safety and efficacy of 12 weeks treatment with FlowOx, for 1 hour twice daily, when used on patients with diabetic foot ulcers.
- Trial name
- INPRESS (NCT07291817)
- Testing
- FlowOx
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Lo Zhiwen Joseph
Foot Ulcer, Diabetic
Dynamic Plantar Microvascular Skin Response to Compressive Loads in At-risk Diabetic and Healthy Control: a Pilot Study
The purpose of this pilot study is to compare the dynamic response of microcirculation in the skin on the bottom of the big toe after applying controlled plantar stress in 25 diabetic subjects with a history of foot ulcer and 25…
- Trial name
- ILH (NCT01580917)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Temple University
Diabetic Neuropathies, Pain
Functional Imaging of the Therapeutic Effect of Pregabalin in Treatment for Neuropathic Pain
Functional Imaging of the therapeutic effect of Pregabalin in treatment for neuropathic pain in patients with Diabetic Polyneuropathy using proton Magnetic Resonance Spectroscopy (MRS): The aim of our study is to investigate the…
- Trial name
- NCT01180608
- Testing
- MR Spectroscopy
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitair Ziekenhuis Brussel
Painful Diabetic Neuropathy
Eslicarbazepine Acetate as Therapy in Diabetic Neuropathic Pain
The primary objective of this study is to assess the efficacy of Eslicarbazepine acetate (ESL) as therapy in subjects with Diabetic Neuropathic Pain (DNP) over a 15 week treatment phase.
- Trial name
- NCT01129960
- Testing
- Eslicarbazepine acetate (BIA 2-093)
- Where
- Portugal
- Volunteers
- 332 people
- Sponsor
- Bial - Portela C S.A.
Diabetic Neuropathies, Diabetic Neuropathy Peripheral
Determining Patterns In Trial Experiences of Diabetic Neuropathy Patients
Historically, participation in clinical studies is highly skewed towards particular demographic groups of people. This study will invite several participants to gather a wide range of information on clinical trial experiences for…
- Trial name
- NCT05461274
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Diabetic Foot, Foot Ulcer
Telemedicine Follow-up in Primary Health Care for Diabetes-related Foot Ulcers
This study will investigate whether telemedicine follow-up care for people with diabetes-related foot ulcers and people with leg ulcers (without diabetes) in municipal primary health care in collaboration with specialist health…
- Trial name
- DiaFOTo (NCT01710774)
- Testing
- Telemedicine follow-up care
- Where
- 3 sites in Norway
- Volunteers
- 241 people
- Sponsor
- Helse Stavanger HF
Diabetic Foot, Amputation, Surgical
Analyzing Anesthetic Techniques in Diabetic Foot Amputation
Diabetic Foot Amputations: A Comprehensive Review of Anesthetic Procedures and Outcomes Introduction: Diabetic foot is a severe complication of diabetes, often resulting in ulceration, osteomyelitis, and gangrene.
- Trial name
- NCT06552910
- Testing
- Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- Ankara City Hospital Bilkent
Diabetic Foot Ulcer
A Phase 2a Proof of Concept Open-Label, Randomized, Controlled Study to Evaluate the Safety and Efficacy of MDI-1228-mesylate Gel Compared With Standard of Care Alone in Patients With Diabetic Foot Ulcers
The study will evaluate the treatment effect of MDI-1228-mesylate Gel compared with standard of care alone for the complete healing rate at the end of 12 weeks in participants with diabetic foot ulcers (targeted ulcer).
- Trial name
- DFU (NCT06852976)
- Testing
- 0.75% MDI-1228_mesylate gel plus Standard of Care, Standard of Care Alone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Zhuhai Rui-Inno Pharmaceutical Technology Co., Ltd.
Diabetic Peripheral Neuropathy
The Effect of Related Blood Markers on Diabetic Peripheral Neuropathy
The goal of this observational study is to explore the relationship between related blood indicators and diabetic peripheral neuropathy(DPN).
- Trial name
- NCT06041412
- Where
- China
- Volunteers
- 1,400 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Diabetic Foot, Diabetes Complications
Local Application of Autologous Bone Marrow Cells for Treatment of Chronic Diabetic Ulcers
Bone marrow cells were previously shown to enhance wound healing in experimental diabetes. In this pilot study, patients with chronic diabetic ulcers not healing under conventional therapy, will be treated with local application…
- Trial name
- NCT00292357
- Testing
- Application of autologous bone marrow
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Heidelberg University
Diabetic Foot, Resistance Exercise
Breathing-based Leg Resistance Exercise Improves Wound Healing, Blood Sugar and Quality of Life for Diabetic Foot Ulcers
The purpose of the study was designed leg resistance training combined with breathing approach, and evaluated its effect on wound healing, blood sugar control and quality of life in type 2 diabetic patients with foot ulcers.
- Conditions
- Diabetic Foot, Resistance Exercise, Wound Healing, Hyperglycemia
- Trial name
- NCT05110092
- Testing
- leg resistance combined with breathing exercise training
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Foot Ulcer, Diabetic
Reduction of Plantar Pressure in Neuropathic Diabetic Foot Patients Using Insoles With Removable Pegs Design
The purpose of this study was to determine if insoles with removable pegs could effectively reduce the plantar aspect pressure with the aid of in-shoe plantar pressure analysis for guidance of peg removal.
- Trial name
- NCT01699100
- Testing
- device
- Volunteers
- 26 people
- Sponsor
- Taichung Veterans General Hospital
Diabetic Foot, Stem Cell
Stem Cell Derived Exome for Treatment of Diabetic Foot
This trial is designed to investigate the safety and efficacy of patients with diabetic foot by using stem cell derived exome.
- Trial name
- NCT06480123
- Testing
- Skin drug prepared with exome originated from stem cell
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Diabetic Neuropathy
A Safety and Efficacy Study for Tapentadol (CG5503) Extended Release for Patients With Painful Diabetic Peripheral Neuropathy
The purpose of this study is to evaluate the effectiveness (level of pain control) and safety of Tapentadol (CG5503) extended release (ER) (base) compared to placebo in patients with moderate to severe pain from diabetic…
- Trial name
- NCT00455520
- Testing
- CG5503
- Volunteers
- 395 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
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