Clinical trials: Neuropathy, Diabetic
Ulcer, Venous Ulcer
ECM and Blood Components for Wound Healing
The Extracellular Matrix (ECM) and Blood Components for Wound Healing feasibility study is a clinical trial approved by Health Canada to study the safety of extracellular matrix (ECM) and autologous blood products in wound…
- Conditions
- Ulcer, Venous Ulcer, Foot Ulcer, Diabetic
- Trial name
- NCT01909908
- Testing
- ECM, Blood Products, ECM in Blood Products
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Cook Group Incorporated
Peripheral Neuropathy, Autonomic Neuropathy
Autonomic Nervous System Dysfunction and Peripheral Neuropathy in a Cohort of Asymptomatic Juvenile Diabetic Patients (Type I): A Case-Controlled Study
This is a case-controlled study using an innovative, non-invasive, FDA approved technology to measure the autonomic nervous system.
- Trial name
- NCT00466778
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Weintraub, Michael I., MD, FACP, FAAN
Diabetic Neuropathic Ulcer
Allogeneic ABCB5-positive Stem Cells for Treatment of DFU "Malum Perforans"
The aim of this clinical trial is to investigate the efficacy (by monitoring the wound surface area reduction of Diabetic Foot Ulcers) and safety (by monitoring adverse events) of two doses of the allogeneic investigational…
- Trial name
- NCT03267784
- Testing
- allo-APZ2-DFU
- Where
- 7 sites in Germany
- Volunteers
- 23 people
- Sponsor
- RHEACELL GmbH & Co. KG
Diabetic Foot Ulcers
Postmarket Study to Evaluate Biovance® in Diabetic Foot Ulcers
The purpose of this study is to compare the wound closure outcomes of subjects receiving diabetic foot ulcer treatment with and without the use of Biovance®.
- Trial name
- NCT02506452
- Testing
- Biovance®, Standard of Care, Diabetic Foot Ulcers
- Where
- 10 sites in United States
- Volunteers
- 51 people
- Sponsor
- Alliqua BioMedical, Inc
Neuropathy
Efficacy of Near Infrared Phototherapy in Type 2 Diabetic Neuropathy
This is a double blind, randomized, placebo-controlled study in which a total of 120 patients will be selected from a broad spectrum group of typical Americans (all demographics including various races and both genders as well as…
- Trial name
- ResearchNIR (NCT02798393)
- Testing
- Infrared Phototherapy
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Healthlight, LLC
Exercise Addiction, Diabetic Neuropathies
Effects of Aerobic Thai Dance in Patient With Diabetic Peripheral Neuropathy
The goal of this type of study is clinical trial. This to learn about effects of applied aerobic Thai dance exercise on gait balance and sudomotor function in patient with diabetic peripheral neuropathy.
- Trial name
- NCT06061237
- Testing
- Aerobic Thai dance exercise
- Where
- Thailand
- Volunteers
- 44 people
- Sponsor
- Chulalongkorn University
Pressure Injury, Venous Leg Ulcer
Pivotal Study of an Antimicrobial Wound Dressing to Treat Chronic Wounds
The goal of this clinical trial is to assess the impact that the NanoSALV wound dressing can have on managing severe chronic wounds and feasibility for patients, providers, and health systems in different health care settings…
- Conditions
- Pressure Injury, Venous Leg Ulcer, Pressure Injury Stage 2, Pressure Injury Stage III
- Trial name
- NCT05619237
- Testing
- NanoSALV Catalytic
- Where
- 4 sites in Canada
- Volunteers
- 44 people
- Sponsor
- Chester Ho, MD
Painful Diabetic Peripheral Neuropathy (PDPN), Acupressure
The Effect of Acupressure on Symptoms in Elderly Adults With Painful Diabetic Neuropathy
This project aims to evaluate the effects of acupressure applied to elderly individuals with painful diabetic peripheral neuropathy (DPN) on neuropathic symptoms, balance confidence, fear of falling, and quality of life.
- Trial name
- NCT07392619
- Testing
- acupressure
- Volunteers
- 76 people
- Sponsor
- Nigde Omer Halisdemir University
Diabetic Foot Ulcers, Wound Care
A Randomized Comparison of AmnioClear™ Human Allograft Amniotic Membrane vs. Moist Wound Dressing in the Treatment of Diabetic Wounds
This research project is testing a product called AmnioClear™ which is an amniotic membrane graft processed for Liventa Bioscience formerly AFCell Medical.
- Trial name
- NCT02120755
- Testing
- AmnioClear™ Human Allograft Amniotic Membrane
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Liventa Bioscience
Diabetes, Diabetic Foot
Assessing the Efficacy of Anti-staphylococcal Phages in the Management of Infected Foot Ulcers in Diabetes
Work Package 1: Observational cohort pilot safety study Work Package 2: Randomised, double-blind, placebo controlled pilot study Work Package 3: Observer-blind pilot RCT
- Conditions
- Diabetes, Diabetic Foot, Diabetic Foot Infection
- Trial name
- PDFI (NCT04289948)
- Testing
- Phage
- Where
- United Kingdom
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Diabetic Foot, Staphylococcal Infections
Standard Treatment Associated With Phage Therapy Versus Placebo for Diabetic Foot Ulcers Infected by S. Aureus
The primary objective of this study is to compare the efficacy of standard treatment associated with a topical anti-staphylococcal bacteriophage cocktail versus standard treatment plus placebo for diabetic foot ulcers…
- Trial name
- PhagoPied (NCT02664740)
- Testing
- Topical anti-Staphylococcus bacteriophage therapy
- Where
- 6 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Diabetic Peripheral Neuropathy, Postmenopausal Women
Effect Whole Body Vibration on Balance in Post Diabetic Menopause Women
Postmenopausal diabetic women have significant balance deficits and increased fall risk. Whole-body vibration may improve balance in these population but needs further research.
- Trial name
- NCT06937008
- Testing
- Whole body vibration, Balance training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Neuropathy, Diabetes Mellitus
Surface Electromyography Study of Fatigue in Diabetic Neuropathy
Fatigue in diabetic neuropathy compromises patients' physical activity and poses questions on how to plan correct rehabilitation training.
- Trial name
- NCT04467255
- Testing
- Rehabilitative training
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Diabetic Foot Ulcer
RESPOND Restoring Equilibrium and Wound Stimulation to Promote Healing Of Non-healing DFUs
To evaluate the safety and effectiveness of MIST Therapy in conjunction with Standard of Care (SOC) compared to Standard of Care alone in the treatment of diabetic foot ulcers (DFU).
- Trial name
- NCT01608776
- Testing
- MIST Therapy, SOC - Standard of Care
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Celleration, Inc.
Diabetic Neuropathy
VEGF Gene Transfer for Diabetic Neuropathy
This gene therapy study is being conducted to evaluate intramuscular gene transfer using VEGF (Vascular Endothelial Growth Factor) in patients with diabetic neuropathy in the legs.
- Trial name
- NCT00056290
- Testing
- VEGF
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Losordo, Douglas, M.D.
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Three-dimensional Measurements of Diabetic Foot Ulcers
Diabetic foot ulcers constitute an increasing health problem in Denmark concurrent with an ageing population and an increase in diabetes prevalence. Diabetic foot ulcers belong to the most serious and costly complications.
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetes Complications, Diabetic Foot
- Trial name
- NCT02423850
- Testing
- 3D Wound Assessment Monitor (WAM) camera
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Odense University Hospital
Infection, Soft Tissue, Infection, Wound
Direct Antibiotic Delivery of Cefazolin Into Soft Tissue Infections Using Subcutaneous Injection and Ultrasonic Dispersion
This study focuses on a new drug delivery system (Direct Antibiotic Delivery) to treat soft tissue infections. In this study, cefazolin is delivered directly to the target tissues using subcutaneous injection of antibiotic…
- Conditions
- Infection, Soft Tissue, Infection, Wound, Cellulitis, Diabetic Foot Ulcer
- Trial name
- DAD (NCT01238276)
- Testing
- Cefazolin, Silberg Tissue Preparation System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sonescence, Inc.
Diabetic Neuropathy, Painful
Study of CBME in the Relief of Painful Diabetic Neuropathy
The study is designed to investigate the benefit of adding CBME to the existing treatment regime in the management of painful neuropathy. Hypothesis: 1.
- Trial name
- NCT00238550
- Testing
- Cannabis based medicine extract (CBME)
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Diabetic Foot, Staphylococcus Aureus
The Foot in Your Nose Study: Links Between Nasal Staphylococcus Aureus Colonies and Diabetic Foot Lesion Infections
The presence of S aureus in the nasal passages of diabetic patients may be a risk factor for diabetic foot lesion infections. Our aim is to compare the genetic profiles of S aureus strains found in the noses and on the foot…
- Trial name
- NCT01212120
- Testing
- Genetic profiling of bacterial cultures
- Where
- 4 sites in France
- Volunteers
- 278 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Diabetic Foot Ulcers
Effect of Topic Pirfenidone in Diabetic Ulcers
Pirfenidone is a synthetic molecule, which acts as a potent modulator of the effect of various cytokines (TNF-α, transforming growth factor-β, platelet derived growth factor and vascular endothelial growth factor, among others)…
- Trial name
- PirDFI (NCT02222376)
- Testing
- Pirfenidone, Debridement
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
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