Clinical trials: Neuropathy, Painful
Piriformis Syndrome, Lumbar Radiculopathy
Investigation of the Presence of Piriformis Syndrome Accompanying Lumbar Radiculopathy
Piriformis syndrome is a neuromuscular disorder that is characterized by piriformis muscle tenderness, hip, and leg pain, and may be accompanied by compression or irritation of the sciatic nerve under the piriformis muscle.
- Trial name
- NCT05392933
- Testing
- Ultrasound guided piriformis muscle lidocaine injection
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Istanbul University - Cerrahpasa
Cancer of the Gastrointestinal Tract
Prevention of Neuropathic Pain From Oxaliplatin by Photobiomodulation
Peripheral neuropathy is one of the most common side effects of oxaliplatin (OXA)-based chemotherapy for patients treated for digestive cancers, disabling and dose-limiting.
- Trial name
- NCT06199115
- Testing
- Photobiomodulation
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Saint-Gregoire Private Hospital Center
Sacroiliac Joint Pain
Effects of KinesioTaping Versus Dry Needling in the Treatment of Sacroiliac Joint Pain Among Females.
The goal of this randomized controlled trial was to investigate the effects of kinesio taping and dry needling on sacroiliac joint (SIJ) pain due to piriformis muscle tightness among females aged 20 to 50 years.
- Trial name
- NCT06755125
- Testing
- Kinesio Taping, Dry Needling
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Sehat Medical Complex
Sciatica, Sciatica Pain
Comparing the Effectiveness of Tensioner Vs Slider Neurodynamic Techniques in Patients With Sciatica
objective of this randomized controlled trial is to examine the efficacy of both tensioner and slider neurodynamic approaches in patients suffering from sciatica.
- Trial name
- NCT07632612
- Testing
- Slider Neurodynamic Technique Group, Tensioner Neurodynamic Technique Group
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Ibadat International University, Islamabad
Burning Pain, Impaired Balance
Feasibility Study of New Method of Diagnostic and Prediction of Painful CIPN
This clinical trial studies how well Diode laser fiber type Selective Stimulator (DLss) works in predicting pain development in patients with ovarian cancer who are receiving chemotherapy.
- Conditions
- Burning Pain, Impaired Balance, Malignant Ovarian Neoplasm, Numbness
- Trial name
- NCT03206216
- Testing
- Diode Laser fiber type Selective Stimulator (DLss)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stanford University
Sciatica, Lumbosacral Radiculopathy
Mechanical Diagnosis and Treatment and/or Steroid Injections for Lumbar Radiculopathy
Aim 1: The primary aim of this study is to test the feasibility of Mechanical Diagnosis and Treatment (MDT) +/- transforaminal epidural steroid injections (TESI) on pain and disability in patients awaiting physiatry consult for…
- Conditions
- Sciatica, Lumbosacral Radiculopathy, Lumbar Disc Rupture
- Trial name
- NCT02951377
- Testing
- Exercise (MDT approach), Transforaminal epidural steroid injection (20mg dexamethasone 0.5cc lidocaine 2%)
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- University of Alberta
Painful Diabetic Neuropathy, Neuropathic Pain
Peripheral Nerve Block in Patients With Painful Diabetic Polyneuropathy
The purpose of the present study is to evaluate the role of peripheral afferent input for spontaneous pain in painful diabetic polyneuropathy
- Conditions
- Painful Diabetic Neuropathy, Neuropathic Pain, Neuropathy;Peripheral
- Trial name
- NCT04699734
- Testing
- Xylocaine 1%, NaCl 9mg/ml
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- University of Aarhus
Hand Osteoarthritis, Trigger Finger
Does Adding Lidocaine to Corticosteroid Injections Reduce Pain Intensity in Hand Surgery
The purpose of this study was to determine whether adding Lidocaine to Corticosteroid injections reduce pain intensity in hand surgery.
- Conditions
- Hand Osteoarthritis, Trigger Finger, Carpal Tunnel Syndrome
- Trial name
- NCT06188221
- Testing
- Lidocaine, Corticoids
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Chronic Pancreatitis
Pain Phenotypes in Chronic Pancreatitis
Chronic pancreatitis (CP) is characterised by recurrent abdominal pain. The pathological hallmarks of CP is pancreatic stellate cell activation that results in persistent inflammation and progressive fibrosis.
- Trial name
- PIP (NCT05713344)
- Testing
- Clinical history, Clinical examination, Evaluation of quality of life
- Where
- India
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Diabetic Peripheral Neuropathic Pain
A Study of Medical Cannabis Aerosol Via the Fixed-dose Syqe Inhaler as an Add-on Treatment of Diabetic Peripheral Neuropathic Pain (DPNP)
The primary purpose of this study is to evaluate the safety and efficacy of medical cannabis aerosol containing 0.25, 0.50, 1.0 milligrams (mg) delta (Δ) 9-tetrahydrocannabinol (THC) inhaled three times a day (TID) compared to…
- Trial name
- NCT06490445
- Testing
- Medical Cannabis
- Where
- 38 sites in Australia, Czechia and 3 more
- Volunteers
- 122 people
- Sponsor
- Syqe Medical
Chemotherapy-induced Peripheral Neuropathy
Use of Repetitive Transcranial Magnetic Stimulation in Cancer Patients With Chemotherapy-Induced Peripheral Neuropathy
The study aims to evaluate the feasibility of a repetitive transcranial magnetic simulation (rTMS) protocol developed for managing pain and other related symptoms associated with chemotherapy-induced peripheral neuropathy in…
- Trial name
- NCT04107272
- Testing
- Real repetitive transcranial magnetic stimulation
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Piriformis Syndrome
Comparison of Effectiveness Between Active Release Technique and Hold Relax Technique in Patients With Piriformis Syndrome
This study is a randomized controlled trial and the purpose of this study is to compare the effects between active release technique and hold relax technique in patients with Piriformis syndrome.
- Trial name
- NCT06437327
- Testing
- Electrotherapy, Active release technique, Hold relax technique
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Painful Diabetic Neuropathy
A Phase 2, Multicenter, Randomized, Double-blind, Placebo Controlled Study for the Pain of Diabetic Peripheral Neuropathy
Primary Objective: To evaluate the efficacy of SKL11197 for the treatment of diabetic peripheral neuropathy pain (DPN). Secondary Objective: To evaluate the safety and tolerability of SKL11197 in subjects with painful diabetic…
- Trial name
- NCT01521598
- Testing
- SKL11197
- Where
- 13 sites in United States
- Volunteers
- 128 people
- Sponsor
- SK Life Science, Inc.
Neuropathic Pain, Quality of Life
Neuropathic Pain and Type II Diabetic Patients
Diabetes Mellitus (DM) is a common metabolic disease characterized by hyperglycemia resulting from insufficiency, deficiency or absence of the insulin hormone.
- Conditions
- Neuropathic Pain, Quality of Life, Diabetic Neuropathies
- Trial name
- NCT06798181
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Neuropathy, Pain
Clinical Study for Assessment of the Efficacy of Gabapentin (Carbatin and Neurontin) in Patients With Neuropathy Pain
The purpose of this study is to assess the efficacy of Gabapentin (Carbatin \& Neurontin) in patients with neuropathy pain.
- Trial name
- NCT02074267
- Testing
- Carbatin, Neurontin
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Nang Kuang Pharmaceutical Co., Ltd.
Peripheral Neuropathy, Painful Neuropathy
Earlier Diagnosis of Peripheral Neuropathy Using A Simple sCreening Tool (ACT)
This study is looking at people with diabetes (type 1 and type 2 diabetes) to see how well a short questionnaire, called the ACT, can identify nerve damage in the feet and legs (also known as peripheral neuropathy).
- Conditions
- Peripheral Neuropathy, Painful Neuropathy, Diabetes (DM)
- Trial name
- ACT (NCT07163000)
- Where
- Qatar
- Volunteers
- 150 people
- Sponsor
- Weill Cornell Medical College in Qatar
Diabetic Neuropathies
A Study on the Efficacy and Safety of Gabapentin in the Treatment of Patients With Painful Diabetic Neuropathy
The purpose of this study was to evaluate the efficacy, safety, and tolerability of gabapentin for the treatment of patients with painful diabetic neuropathy. The quality of life of all treated patients was also assessed.
- Trial name
- NCT00644748
- Testing
- gabapentin
- Where
- 10 sites in Brazil
- Volunteers
- 95 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pain
Study to Evaluate the Efficacy and Safety of OraVescent Fentanyl Citrate Treatment for the Management of Breakthrough Pain in Opioid-Tolerant Patients With Noncancer-Related Chronic Pain
The purpose of the study is to evaluate the efficacy and safety of OraVescent fentanyl treatment compared to placebo treatment monthly over a 12-week treatment period in alleviating breakthrough pain (BTP) in opioid-tolerant…
- Trial name
- NCT00343733
- Testing
- OraVescent Fentanyl
- Where
- 21 sites in United States
- Volunteers
- 120 people
- Sponsor
- Cephalon
Carpal Tunnel Syndrome
Effects of Kinesiotaping With and Without Active Release Technique in Patients With Carpal Tunnel Syndrome
The goal of this study is to compare the effects of Kinesiotaping and Active Release Technique in patients with CTS to see which method is better for improving Pain, Grip Strength, Range of Motion and functional disability.
- Trial name
- NCT05354011
- Testing
- Kinesiotape, Active Release Technique
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Small Fiber Neuropathy, Diabetes Mellitus
Efficacy and Safety Study of BIIB074 in Participants With Small Fiber Neuropathy
The primary objective of this study is to evaluate the efficacy of BIIB074 in treating pain experienced by participants with confirmed small fiber neuropathy (SFN) that is idiopathic or associated with diabetes mellitus.
- Trial name
- NCT03339336
- Testing
- BIIB074
- Where
- 97 sites in Bulgaria, Canada and 12 more
- Volunteers
- 265 people
- Sponsor
- Biogen