Clinical trials: Neuropathy (Disorder)
Diabetes Mellitus Foot Ulcer
Platelet Rich Plasma and Autologous Fat Graft for Diabetic Ulcer
Conventional management of diabetic ulcers is associated with slow healing, high costs and repeated trips to clinic. Stem cells contained in fat grafts can differentiate into pro-healing cells and release growth factors with…
- Trial name
- NCT03085550
- Testing
- Fat grafting, Fat grafting + platelet rich plasma
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University College, London
Cancer of the Breast, Chemotherapy-induced Neuropathy
DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY
Up to 80% of breast cancer survivors experience chemotherapy-induced neuropathy that impairs quality of life and increases fall risk long into survivorship, yet treatment options for neuropathy remain limited.
- Trial name
- DAANCE (NCT06749210)
- Testing
- Tango
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Peripheral Neuralgia, Peripheral Neuropathy
Clinical Study of a Micro-Implantable Pulse Generator for the Treatment of Peripheral Neuropathic Pain (COMFORT 2)
This post market study is being conducted to document the comparative effectiveness and safety of peripheral nerve stimulation plus conventional medical management versus conventional medical management alone in the treatment of…
- Conditions
- Peripheral Neuralgia, Peripheral Neuropathy, Chronic Pain
- Trial name
- COMFORT 2 (NCT05870124)
- Testing
- Nalu Neurostimulation System for PNS, Conventional Medical Management
- Where
- 17 sites in United States
- Volunteers
- 185 people
- Sponsor
- Nalu Medical, Inc.
Gastric Retention
Impact of Neuropathy on the Risk of Semaglutide-Induced Gastric Retention
A prospective, single-center, observational study to compare the risk of gastric retention between the exposure group (with neuropathy) and non-exposure group (without neuropathy) in diabetic patients receiving uninterrupted…
- Trial name
- NCT07156591
- Testing
- Esophagogastroduodenoscopy
- Where
- China
- Volunteers
- 460 people
- Sponsor
- Fudan University
Diabetic Polyneuropathy
Peripheral Nerve Stimulation in Diabetic Patients
The prevalence of diabetes mellitus (DM) in industrialized countries is estimated to be about 7.3% and its incidence has been growing in recent years.
- Trial name
- NCT01488474
- Testing
- peripheral nerve stimulation
- Where
- Austria
- Volunteers
- 124 people
- Sponsor
- Medical University of Graz
Cardiac Amyloidosis, Spinal Stenosis
Prevalence of Cardiac Amyloidosis Among Patients With a History of Lumbar Spinal Stenosis.
The study investigates the prevalence of cardiac amyloidosis among patients with a history of lumbar spinal stenosis within the last ten years in the region of central Denmark.
- Trial name
- CASS-I (NCT05701410)
- Testing
- DPD scintigraphy
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Steen Hvitfeldt Poulsen
Leprosy, Leprosy Neuropathy
Accuracy of the Polymerase Chain Reaction of Ulnar Perineural Subcutaneous Aspirate Guided by Ultrasound for the Diagnosis and Monitoring of Leprosy Cure
Brief Summary Leprosy is a chronic granulomatous infectious disease caused by *Mycobacterium leprae* or *Mycobacterium lepromatosis*, characterized by peripheral nerve involvement that may lead to progressive neurological damage…
- Conditions
- Leprosy, Leprosy Neuropathy, Leprosy, Multibacillary, Leprosy--Patients
- Trial name
- Does not exist (NCT07515989)
- Testing
- Ultrasound-Guided Ulnar Perineural Subcutaneous Aspirate
- Where
- Brazil
- Volunteers
- 108 people
- Sponsor
- University of Brasilia
Diabetic Neuropathy, Painful
Study With Two Capsaicin Topic Treatments in Diabetic Neuropathy.
Clinical trial of "line extension" of drug ARAFARMADOL® 0.075% cream in a new formulation in topical solution applicable in roll-on and with the same therapeutic indications approved for the cream.
- Trial name
- NCT05029297
- Testing
- Capsaicin
- Volunteers
- 161 people
- Sponsor
- Arafarma Group, S.A.
Chronic Pain, Complex Regional Pain Syndromes
The Success of Lumbar Sympathetic Ganglion Block Using Lower Extremity Perfusion Index
The patient, who is experiencing chronic pain in the lower extremities persisting for more than three months, is scheduled to undergo lumbar sympathetic ganglion block.
- Conditions
- Chronic Pain, Complex Regional Pain Syndromes, Peripheral Neuropathy, Post Herpetic Neuralgia
- Trial name
- NCT06241820
- Testing
- Lumbar Sympathetic Ganglion Block
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Jeongsoo Kim
Negative-Pressure Wound Therapy, Diabetic Foot
Comparison Between Negative Pressure Wound Therapy and Conventional Wound Dressings Before and After Split-Thickness Skin Grafting in Diabetic Foot Wounds
The aim of this thesis is to compare the efficacy of Vacuum assisted closure device versus conventional dressing before and after split thickness skin grafting in diabetic foot wounds.
- Trial name
- NCT05716503
- Testing
- Negative Pressure Wound Therapy (NPWT), Ordinary dressings with antibiotic ointment and gauze
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Piriformis Muscle Syndrome, Dry Needling
Efficacy of Ultrasound-Guided Dry Needling Therapy and Exercise in Piriformis Muscle Syndrome
Piriformis muscle syndrome (PMS) is a neuromuscular disorder that can cause symptoms of hip joint motion limitation, buttock pain and tenderness, and numbness radiating to the back of the thigh due to compression or irritation of…
- Conditions
- Piriformis Muscle Syndrome, Dry Needling, Ultrasonography, Ultrasound Guided Dry Needling
- Trial name
- NCT05962515
- Testing
- ultrasound guided dry needling
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Tepecik Training and Research Hospital
Metastatic Breast Cancer
Non-interventional Study With Nab-Paclitaxel (Abraxane®)
The purpose of this non-interventional study is to collect data on the efficacy and safety of Nab-Paclitaxel in the routine application.
- Trial name
- NABUCCO (NCT01689610)
- Where
- Germany
- Volunteers
- 705 people
- Sponsor
- iOMEDICO AG
Small Fiber Neuropathy, Fabry Disease
Assessment of Small Fiber Neuropathy in Rare Diseases Using Sudoscan
Sudoscan™ (Impeto Medical, Paris France) uses electrochemical skin conductance as a novel noninvasive method to detect sudomotor dysfunction.
- Conditions
- Small Fiber Neuropathy, Fabry Disease, Ehlers Danlos Syndrome, Mitochondrial Disease
- Trial name
- NCT02985710
- Testing
- Sudoscan, Skin biopsy, QSART
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Charcot Marie Tooth Disease (CMT), Pes Cavovarus
Walking Function Outcomes Following Surgical Correction With Rehabilitation Versus Physical Therapy Alone in Charcot-Marie-Tooth Disease: A Bidirectional Cohort Study
The goal of this study is to compare changes in walking ability in people with Charcot-Marie-Tooth disease (CMT) who receive two different treatment approaches for foot deformities that affect walking.
- Conditions
- Charcot Marie Tooth Disease (CMT), Pes Cavovarus, Surgery, Exercise Training
- Trial name
- CMT-WALK (NCT07432035)
- Testing
- Functional Surgery plus Rehabilitation, Physical Exercise
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Breast Neoplasms, Chemotherapy-induced Peripheral Neuropathy
Transcutaneous Electrical Acupoint Stimulation on Symptoms Associated with Chemotherapy Induced Peripheral Neuropathy
Breast cancer ranks first in Taiwan's top ten gynecological cancers. Chemotherapy is a standard treatment method for colorectal cancer and breast cancer, but while destroying cancer cells, it also destroys healthy cells…
- Trial name
- NCT05904340
- Testing
- Transcutaneous Electrical Nerve Stimulation
- Where
- Taiwan
- Volunteers
- 86 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Type 1 Diabetes
Association Between Sarcopenia And Diabetic Neuropathy In Adults With Type 1 Diabetes, A Pilot Study
Monocentric interventional prospective study to evaluate the prevalence of sarcopenia in adults with type 1 diabetes (T1DM) and to evaluate the association between diabetic neuropathy and sarcopenia in subjects with T1DM; to…
- Trial name
- SARCO_DM1 (NCT06902597)
- Testing
- Dual energy X-ray absorptiometry
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Diabetic Foot Ulcer
Plantar Pressure Distribution in Diabetic Foot Ulcer
The goal of this clinical trial is to find out the changes in peak pressure and pressure-time integral after twelve weeks from the initial utility of foot insoles and eight weeks later as a follow-up in diabetic foot ulcers.
- Trial name
- PPDDFU (NCT05888259)
- Testing
- foot insole
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Peripheral Neuropathy With Type 2 Diabetes
A Physiologic Comparison of Two Approaches to Treating Peripheral Neuropathy
Diabetic peripheral neuropathy is one of the most common and costly microvascular complications of diabetes impacting more than 50% of patients and costing more than 10.1 billion dollars annually.
- Trial name
- NCT05577390
- Testing
- Intraneural Facilitation Therapy Treatment, Standard Physical Therapy Treatment
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Loma Linda University
Auditory Neuropathy Spectrum Disorder,, Peripheral Neuropathy
Prevalence of Peripheral Neuropathy Among Patients With Auditory Neuropathy
Auditory neuropathy/ dys-synchrony/ peri-synaptic audiopathy (AN) are terms used to describe a specific hearing disorder with a disturbed auditory neural response in presence of normal cochlear function.
- Trial name
- NCT06041360
- Testing
- Pure tone audiometry PTA ,Speech audiometry ,Otoacoustic emission,Auditory evoked potentials including (ABR).
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
HIV Infections
Effects of TENS and Mindfulness Meditation in Persons With HIV-related Neuropathy
This study is to explore the effects of transcutaneous nerve stimulation (TENS) and mindfulness meditation in persons living with HIV (PLHIV) and painful neuropathy in the feet.
- Trial name
- NCT04868123
- Testing
- Transcutaneous Nerve Stimulation (TENS), Mindfulness Meditation
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Rutgers University
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