Clinical trials: Neuropathy (Disorder)
Intervertebral Disc Displacement, Sciatica
The Effectiveness of Doin (Conduction Exercise) of the Pelvic Joint for HLD With Radiating Leg Pain
A prospective pilot study will be conducted to investigate the effectiveness and safety in herniated lumbar disc (HLD) patients receiving integrative Korean medicine treatment including Doin (conduction exercise) at a Korean…
- Conditions
- Intervertebral Disc Displacement, Sciatica, Sciatic Radiculopathy
- Trial name
- NCT03571503
- Testing
- Doin (conduction exercise), Herbal medicine, Chuna manual therapy
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Jaseng Medical Foundation
Diabetic Foot
Clinical Trial for the Treatment of Diabetic Foot Ulcers Using a Nitric Oxide Releasing Patch: PATHON
Diabetes Mellitus constitutes one of the most important public health problems due to its high prevalence and enormous social and economic consequences.
- Trial name
- NCT00428727
- Testing
- Controlled nitric oxide releasing patch
- Where
- Colombia
- Volunteers
- 100 people
- Sponsor
- Fundación Cardiovascular de Colombia
Lower Extremity or Diabetic Foot Ulcers, Bacterial Infection
Larval Debridement Therapy Versus Sharp Debridement to Remove Biofilm
This is a prospective study of Veterans with chronic lower extremity or diabetic foot ulcers who will be randomized to either a Larval Debridement Therapy group (Biobags every 4 days x 2 applications) or a Sharp Debridement…
- Trial name
- NCT02294175
- Testing
- Larval Debridement Therapy, Bedside Sharp Debridement
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- North Florida Foundation for Research and Education
Diabetic Foot Ulcer Healing Trajectories
Efficacy of Negative Pressure Wound Therapy Versus Conventional Moist Dressings on Diabetic Foot Ulcer Healing Trajectories
Background: Diabetic foot ulcers (DFUs) are severe, chronic complications of diabetes carrying a high risk of amputation. While Negative Pressure Wound Therapy (NPWT) is an active biophysical treatment, clinical evidence using…
- Trial name
- DF-WOUND-RCT (NCT07745075)
- Testing
- Vacuum-Assisted Closure (VAC / NPWT)
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jerash Private University
Diabetic Neuropathy
Efficacy Study With 500 mg QD of TRO19622 vs Placebo in Patients With Painful Peripheral Diabetic Neuropathy
The purpose of this study is to assess the efficacy and safety of TRO19622 administered PO daily for 6 weeks compared to placebo administered PO daily in patients with painful peripheral diabetic neuropathy.
- Trial name
- NCT00496457
- Testing
- Experimental
- Where
- 31 sites in Croatia, Germany and 3 more
- Volunteers
- 159 people
- Sponsor
- Hoffmann-La Roche
Diabetic Foot Ulcers
Evaluation of the Effect of Vivostat Platelet Rich Fibrin(PRF) in the Treatment of Diabetic Foot Ulcers
Diabetic foot ulcers are a challenge to health care professionals because there are only few effective topical therapeutic interventions.
- Trial name
- NCT00770939
- Testing
- Vivostat PRF
- Where
- 5 sites in Denmark, Germany and 1 more
- Volunteers
- 60 people
- Sponsor
- Vivostat
Chemotherapy-Induced Peripheral Neuropathy, Hematopoietic and Lymphoid Cell Neoplasm
Whole Body Vibration for the Improvement of Health and Functioning in Participants With Chemotherapy-Induced Peripheral Neuropathy
This clinical trial studies how well whole body vibration works in improving the health and functioning of participants with chemotherapy-induced peripheral neuropathy.
- Conditions
- Chemotherapy-Induced Peripheral Neuropathy, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT04170075
- Testing
- Whole Body Vibration
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- OHSU Knight Cancer Institute
Healthy
Bioequivalence Study of Two Formulations of Pregabalin CR (Controlled-release) Table 150 mg
The purpose of this clinical trial is to (1) evaluate the bioequivalence(BE) of GLA5PR GLARS-NF3 tablet 150mg administered regular diet relative to GLA5PR GLARS-NF1 tablet 150mg administered regular diet and (2) determine the…
- Trial name
- NCT02955472
- Testing
- GLA5PR GLARS-NF3 tablet 150mg, GLA5PR GLARS-NF1 tablet 150mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GL Pharm Tech Corporation
Diabetic Neuropathies
Effects of Benfotiamine on Intraepidermal Nerve Fiber Density (IENFD)
The aim of the present study is to assess before, as well as 6 and 12 months following a therapy with benfotiamine the influence of therapy on intraepidermal nerve fiber density (skin biopsy) and neuropathic symptoms and deficits…
- Trial name
- NCT01868191
- Testing
- Benfotiamine
- Where
- Germany
- Volunteers
- 22 people
- Sponsor
- Diabetes Schwerpunktpraxis
Carpal Tunnel Syndrome
PAVmed CarpX Device Clinical Study
To study the safety and feasibility of the CarpX device to divide and release the transverse carpal ligament in order to provide relief for Carpal Tunnel Syndrome (CTS).
- Trial name
- NCT03747510
- Testing
- CarpX Device
- Where
- New Zealand
- Volunteers
- 20 people
- Sponsor
- PAVmed Inc.
Carpal Tunnel Syndrome, Median Nerve Entrapment
Hydrodissection in Carpal Tunnel Syndrome
The aim of this study was to compare the effectiveness of perineural hydrodissection methods performed with 5 mL D5W solution and three different injection techniques [ultrasound-guided in-plane, ultrasound-guided out-of-plane…
- Trial name
- KTS (NCT07207460)
- Testing
- Comparison of three different injection techniques using hydrodissection with 5% dextrose in the treatment of CTS
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Ankara City Hospital Bilkent
Peripheral Neuropathy
SINF: Peripheral Neuropathy in Cancer Survivors
The goal of this clinical research study is to learn if one acupuncture treatment approach is more effective than another in helping to relieve neuropathy in cancer patients.
- Trial name
- NCT02168894
- Testing
- Acupuncture, Nerve Function Tests, Questionnaires
- Sponsor
- M.D. Anderson Cancer Center
Diabetes
Investigating Ultrasound Debridement in Wound Care
The initial step of wound management, debridement, is thought to be critical in promoting wound healing. Of the numerous debridement modalities, ultrasound seems to hold promising results in accelerate healing in our own clinical…
- Trial name
- NCT03516422
- Testing
- ULTRASOUND DEBRIDEMENT, STANDARD CARE GROUP
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Diabetic Foot
Repeated Educational Intervention for the Prevention of Diabetic Foot Ulcers in High-risk Patients
Following a prior observation that a brief structured group educational intervention is effective for the prevention of diabetic foot ulcers in high-risk patients, but that the efficacy decreases over the time, this study is…
- Trial name
- NCT03555656
- Testing
- Repeated intervention, Single session
- Where
- Italy
- Volunteers
- 89 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Pain
Efficacy and Safety Study of Ataciguat Versus Placebo in Patients With Neuropathic Pain
The primary objective of this study is to assess the efficacy of ataciguat versus placebo in reducing pain intensity in patients with neuropathic pain.
- Trial name
- SERENEATI (NCT00799656)
- Testing
- ataciguat (HMR1766)
- Where
- 3 sites in Austria, Czechia and 1 more
- Volunteers
- 62 people
- Sponsor
- Sanofi
MS (Multiple Sclerosis)
Effect of Robot-assisted Training on Foot Drop in Multiple Sclerosis
The primary aim of this study is to: 1. Collect pilot data on the effect of task-specific lower extremity training using the Anklebot on subjects with Multiple Sclerosis (MS) and who have foot drop; 2.
- Trial name
- NCT00872053
- Testing
- Anklebot, Lokomat
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- US Department of Veterans Affairs
Carpal Tunnel Syndrome
Topical Cannabidiol for Treating Carpal Tunnel Syndrome
The Purpose of this study is to assess the safety and efficacy of Cannabidiol on treatment of Carpal Tunnel Syndrome.
- Trial name
- NCT06108349
- Testing
- Cannabidiol
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Diabetic Foot - Telemedical Monitoring, Diabetic
Virtual Reality-Based 'Health at My Feet' Program for Individuals With Type 2 Diabetes
This randomized controlled experimental study aims to develop and evaluate the effectiveness of a Virtual Reality-Based "Health to My Foot" program designed for individuals with Type II Diabetes Mellitus.
- Conditions
- Diabetic Foot - Telemedical Monitoring, Diabetic, Foot Care, Virtual Reality
- Trial name
- NCT07473050
- Testing
- "Health for My Feet" virtual reality program.
- Volunteers
- 70 people
- Sponsor
- Ege University
Diabetic Foot Ulcers
A Clinical Study of the Safety and Efficacy of MEBO® Wound Ointment in Subjects With Diabetic Foot Ulcers (Pilot)
The objective of this study is to evaluate the safety and efficacy of MEBO in the treatment of subjects with diabetic foot ulcers (DFUs).
- Trial name
- NCT01154374
- Testing
- MEBO Wound Ointment, Standard of Care (sterile saline moistened gauze)
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Skingenix, Inc.
Diabetes Mellitus Foot Ulcer
Multifactorial Strategies for the Prevention of the Risks of Ulceration in Patients Affected by Diabetic Foot (DARE-DiaFoot)
This is a no-profit, multicentre, national, clinical trial for the prevention of the complications of the diabetic foot in two populations of patients with diabetes mellitus type-2.
- Trial name
- DARE-DiaFoot (NCT07021222)
- Testing
- Full Analysis, Partial Analysis
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Ortopedico Rizzoli
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