Clinical trials: Neuropathy (Disorder)
Type 2 Diabetes
The Effect of Foot Reflexology Massage on Neuropathic Pain
This study is conducted to measure the effect of foot reflexology massage on neuropathic pain in diabetic patients.Is reflexology foot massage applied to type 2 diabetic patients effective on neuropathic pain?
- Trial name
- NCT06951412
- Testing
- Foot Reflexology Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- University of Gaziantep
Polyneuropathies, Regional Blood Flow
Comparative Effectiveness of Nursing Interventions: Using Buerger-Allen Exercises Versus Mechanical Compression Therapy on Lower Limb Perfusion and Peripheral Neuropathy Among Patients Undergoing Chemotherapy.
Chemotherapy-induced peripheral neuropathy (CIPN) and impaired lower-limb circulation are common adverse effects that can compromise patients' mobility, comfort, balance, functional independence, and quality of life and may…
- Conditions
- Polyneuropathies, Regional Blood Flow, Lower Extremity
- Trial name
- RCT (NCT07842237)
- Testing
- mechanical compression therapy, Exercises
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Damanhour University
Amyotrophic Lateral Sclerosis, Frontotemporal Dementia
Phenotype, Genotype & Biomarkers in ALS and Related Disorders
The goals of this study are: (1) to better understand the relationship between the phenotype and genotype of amyotrophic lateral sclerosis (ALS) and related diseases, including primary lateral sclerosis (PLS), hereditary spastic…
- Conditions
- Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, Primary Lateral Sclerosis, Hereditary Spastic Paraplegia
- Trial name
- NCT02327845
- Where
- 15 sites in United States, Germany and 1 more
- Volunteers
- 708 people, healthy volunteers welcome
- Sponsor
- University of Miami
Motor Neuropathy, Sensory Neuropathy
Short-term Evaluation of Motor and Sensory Function in Post-COVID-19 Patients
SARS-COV-2 infection reframed medical knowledge in many aspects, yet there is still a lot to be discovered. our aim is to evaluate neurological impact of covid-19; if there is any.
- Trial name
- NCT05721040
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Breast Cancer
Taxane Induced Peripheral Neuropathy in Chinese Patients With Breast Cancer
The purpose of this study is to collect clinical data, blood samples, and self reported symptoms of peripheral neuropathy from Chinese patients with breast cancer after treatment with taxanes.
- Trial name
- NCT04068090
- Testing
- Patient Questionnaires, Blood Collection
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Diabetic Foot Ulcer
BB-101 for the Treatment of Diabetic Lower Leg and Foot Ulcers
This is a randomized, double-blinded, vehicle-controlled, parallel, phase II study to evaluate the efficacy and safety of topical BB-101 for the treatment of diabetic lower leg and foot ulcer.
- Trial name
- NCT06383013
- Testing
- BB-101
- Where
- 5 sites in Taiwan
- Volunteers
- 96 people
- Sponsor
- Blue Blood Biotech Corp.
Diabetes, Peripheral Neuropathy
Motor Learning in Gait in Subjects With Diabetic Peripheral Neuropathy
The purpose of this study is to determine whether individuals with diabetic peripheral neuropathy can learn to change the way they walk in order to reduce the pressures underneath the feet, which may lead to a reduced risk of…
- Trial name
- NCT00223782
- Testing
- Gait Training with Feedback, Gait Training with no feedback
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- US Department of Veterans Affairs
Diabetes, Neuropathy
Improving Autonomic Function and Balance in Diabetic Neuropathy
Type 2 diabetes (DM2) affects nearly 20 million people in the United States while impaired glucose regulation (IGR), which includes impaired glucose tolerance (IGT), impaired fasting glucose (IFG), and early diabetes affects a…
- Conditions
- Diabetes, Neuropathy, Impaired Glucose Tolerance
- Trial name
- IMABIN (NCT01864460)
- Testing
- lifestyle modification
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- VA Office of Research and Development
Diabetic Foot, Immune Defect
Immune Cells in Diabetic Chronic Foot Ulcers
The goal of this observational study is to learn about the role of immune cells in patients with diabetes and chronic foot ulcers.
- Trial name
- NCT06154915
- Testing
- medical treatments
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Carpal Tunnel Syndrome, Compression Neuropathy
Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome
Study Hypothesis: Acetyl-l-carnitine increases nerve regeneration in patients with severe carpal tunnel syndrome. Carpal tunnel syndrome (CTS) is common, affecting almost 3% of the general population.
- Trial name
- NCT02141035
- Testing
- Acetyl-l-carnitine
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Carpal Tunnel Syndrome
Effects of Whole Wrist Versus Specific Carpal Bone Mobilization in the Patients of Carpel Tunnel Syndrome
The study was conducted to compare the effectiveness of Whole Wrist Mobilization versus Specific Carpal Bone Mobilization in reducing symptoms and improving function in patients with Carpal Tunnel Syndrome (CTS).
- Trial name
- NCT07724717
- Testing
- Specific Bone Mobilization, Whole Wrist Mobilization, Standardized Physiotherapy Treatment
- Where
- 2 sites in Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Breast Cancer, Neuropathy
Electro-acupuncture for the Prevention of Taxane Induced Myalgias and Neuropathy
This study seeks to determine if 12 weeks of weekly electro-acupuncture will prevent or decrease neuropathic pain in breast cancer patients receiving 12 weekly treatments of taxane treatment.
- Trial name
- NCT01163682
- Testing
- Electro-acupuncture
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Columbia University
Peripheral Neuropathy, Cancer
L-carnosine Prophylactic Effect on Oxaliplatin Induced Peripheral Neuropathy in GIT Cancer Patients
This study evaluates the prophylactic effect of exogenous L-CARNOSINE in Oxaliplatin induced peripheral neuropathy, Thus half of the patients will receive L-CARNOSINE with Oxaliplatin and the other half will not receive…
- Trial name
- NCT02808624
- Testing
- L-CARNOSINE
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- Cairo University
Dropfoot
Evaluation of Dual Channel vs. Single Channel FES for Dropfoot
Seventy (70) subjects put on the Ness L300 System, a FES device for ankle dorsiflexion for patients with foot drop. Stimulation will be given through two different electrodes: the QFE which is a single channel stimulation, and…
- Trial name
- NCT02494323
- Testing
- Functional Electrical Stimulation
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Bioness Neuromodulation
Wounds, Diabetic Foot Ulcers
Safety and Exploratory Efficacy Study of Collagen Membrane With Mesenchymal Stem Cells in the Treatment of Skin Defects
The purpose of the present study is to evaluate the safety and exploratory efficacy of the medical collagen membrane with umbilical cord derived mesenchymal stem cells in the treatment of patients with skin defects.
- Conditions
- Wounds, Diabetic Foot Ulcers, Burns
- Trial name
- SEESCMMSCTSD (NCT02672280)
- Testing
- Medical Collagen Membrane with MSC, Medical Collagen Membrane
- Volunteers
- 30 people
- Sponsor
- South China Research Center for Stem Cell and Regenerative Medicine
Diabetic Peripheral Neuropathy, Diabetic Neuropathy
Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy
The aim of the current study is to measure the effect of melatonin as adjunct therapy on oxidative stress, inflammatory markers and clinical outcome in type 2 diabetic patients with diabetic peripheral neuropathy.
- Conditions
- Diabetic Peripheral Neuropathy, Diabetic Neuropathy, Diabetic Peripheral Neuropathy in Type 2 Diabetic Patients
- Trial name
- NCT07036796
- Testing
- Melatonin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Lumbosacral Radicular Pain
A Research Study to Characterize the Pharmacodynamics and Safety of Repeat Dose SP-102
This is an open-label, single-arm, repeat dose study to characterize the pharmacodynamics and safety/tolerability of SP-102 administered by epidural injection.
- Trial name
- NCT03613662
- Testing
- SP-102
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Semnur Pharmaceuticals, Inc.
Carpal Tunnel Syndrome
Assessment of Ultrasound Findings, Nerve Test Results, and Hand Function in Patients With Carpal Tunnel Syndrome
Carpal tunnel syndrome is one of the most common conditions caused by compression of a nerve at the wrist. It can lead to numbness, tingling, pain, weakness, and difficulty performing daily activities.
- Trial name
- NCT07752797
- Testing
- Ultrasonographic and Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Peripheral Arterial Disease, Diabetic Foot
Efficacy and Safety of Intramuscular PDA-002 in Subjects With Diabetic Foot Ulcer With and Without PAD.
This is a Phase 2, multicenter, randomized, double-blind, placebo-controlled, dose-ranging study evaluating the efficacy and safety of intramuscular administration of human placenta-derived cells (PDA-002) in subjects with…
- Trial name
- DFU-002 (NCT02264288)
- Testing
- PDA-002
- Where
- 45 sites in United States
- Volunteers
- 159 people
- Sponsor
- Celularity Incorporated
Polyneuropathies
Ultrasonography in Diagnosis of Polyneuropathy
The main goal of this trial is to establish recommendations for clinical practice that enhance the reliability, accessibility and convenience of sheer wave elastography as a routine diagnostic test for diverse peripheral…
- Trial name
- NCT06390527
- Volunteers
- 120 people
- Sponsor
- University Medical Centre Ljubljana
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