Clinical trials: Neuropathy (Disorder)
Sciatica, Lumbar Disc Herniation
Trial of Pulsed Radiofrequency for Sciatica and Disc Herniation
Transforaminal epidural injection of treatments, commonly steroids (TFESI), is offered to people with sciatica and might improve symptoms, reduce disability and speed up return to normal activities (NICE guidelines)…
- Trial name
- PRATS (NCT04209322)
- Testing
- pulsed Radiofrequency, Transforaminal Epidural Steroid Injection
- Where
- 2 sites in Italy
- Volunteers
- 250 people
- Sponsor
- University of Roma La Sapienza
Complications of Diabetes Mellitus, Diabetic Neuropathies
Technological Rehabilitation of Distal Sensorimotor Polyneuropathy in Diabetic Patients
The investigators evaluated the effectiveness of the application of analysing treadmill, muscle strengthening and balance training compared to a control intervention in patients with diabetic neuropathy.
- Trial name
- NCT01926522
- Testing
- Technological Rehabilitation, Control Rehabilitation
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Giovanni Taveggia
Peripheral Neuropathy, Intraoperative Injury
Steep Trendelenburg With or Without Lithotomy Positioning on the Operating Table.
Robotic assisted laparoscopic and laparoscopic gynecological, colon-rectal and urological surgical procedures require that patients be placed in steep Trendelenburg positioning with or without lithotomy on operating table.
- Conditions
- Peripheral Neuropathy, Intraoperative Injury, Intraoperative Complications, Patient Positioning
- Trial name
- NCT05237700
- Testing
- Patient positioning on operating table
- Volunteers
- 500 people
- Sponsor
- Oslo University Hospital
Diabetic Polyneuropathy
HTEMS Treatment of Diabetic Polyneuropathy
So far, there are no sufficient pharmacologic therapies for the treatment of diabetic neuropathy. Therefore, we evaluated application of high-tone external muscle stimulation (HTEMS) compared to placebo treatment in patients with…
- Trial name
- HTEMS-RCT (NCT04593992)
- Testing
- HTEMS
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- West German Center of Diabetes and Health
Gait Disorder, Sensorimotor, Diabetes Mellitus, Type 2
Factors That Effect the Gait Speed in Diabetic Individuals Without Neuropathy
This study planned to investigate the role of potential explanatory factors effecting the speed of gait such as muscle mass, aerobic capacity, physical activity status, cognitive function, blood pressure, and metabolic measures…
- Trial name
- NCT04758364
- Testing
- measurement of gait speed
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people
- Sponsor
- GULIN FINDIKOGLU
CIPN - Chemotherapy-Induced Peripheral Neuropathy, Breast Cancer
Meridian Yoga on Chemotherapy-induced Peripheral Neuropathy in Breast Cancer Patients
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect in breast cancer patients with completion of chemotherapy, and that is characterized by associated clinical symptoms such as pain, tingling, numbness, and…
- Trial name
- CIPN (NCT05959811)
- Testing
- yoga
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- China Medical University Hospital
Carpal Tunnel Syndrome
Comparison of Conventional Versus Transverse Mini-Incision Technique for Carpal Tunnel Release
This study aimed at to fill the gaps by comparing the surgical outcomes of the conventional versus transverse mini-incision technique for carpal tunnel syndrome in terms of pain and functional outcomes.
- Trial name
- NCT07018011
- Testing
- Conventional open CTR, Transverse mini-incision technique
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- RESnTEC, Institute of Research
Congenital Heart Disease in Children, Infant Development
Evaluations of Cardiopulmonary Function and Motor Development of Congenital Heart Disease
In this single-center, randomized controlled trial, patients (4-8 months) with CHD were randomly assigned to either a recovery group (home-based rehab exercise periodically) supervised by cellphone APP or to a control group.
- Conditions
- Congenital Heart Disease in Children, Infant Development, Infant Conditions, Motor Neuropathy
- Trial name
- NCT05518136
- Testing
- exercise-guidance on rehab APP
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Gejingwa Zhao
Peripheral Neuropathy
The Effect of Plantar Vibration on the Progression of Peripheral Neuropathy
The purpose of this study is to assess the effect of vibration of the plantar surface of the foot on peripheral neuropathy.
- Trial name
- NCT00822198
- Testing
- plantar vibration
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Binghamton University
Radiculopathy, Sciatica
Clinical Trial to Evaluate the Safety and Analgesic Efficacy of VVZ-149 in Lumbar Radiculopathy (Sciatica)
Double-blind, crossover, randomized, 3x3 Latin square, placebo-controlled study of single intravenous dose administration of VVZ-149. To demonstrate assay sensitivity, lidocaine will be administered as a positive control.
- Trial name
- LMR (NCT02644421)
- Testing
- VVZ-149, Lidocaine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Brigham and Women's Hospital
Ataxia Telangiectasia, ATM Gene Mutation
Effects of Vitamin B3 in Patients With Ataxia Telangiectasia
This clinical trial investigates the effects of nicotinamide riboside (vitamin B3) on the disease course of patients with ataxia telangiectasia.
- Trial name
- NCT03962114
- Testing
- Vitamin B3
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Radboud University Medical Center
Diabetic Peripheral Neuropathy
Walking Function in Diabetic Peripheral Neuropathy
The purpose of this study is to 1) examine the differences in walking function and movement patterns between individuals with diabetic peripheral neuropathy and healthy adults with no known conditions; 2) examine if receiving…
- Trial name
- NCT05965336
- Testing
- Clinical Evaluation, Evaluation of Passive Ankle Stiffness, Gait Biomechanics
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Florida Institute for Human and Machine Cognition
Diabetic Foot
Removable Walker for Neuropathic Ulcers
1. Objective: To evaluate the efficacy of removable cast walker compared to non-removable fiberglass off-bearing cast in the treatment of diabetic plantar foot ulcer 2.
- Trial name
- NCT01005264
- Testing
- non-removable fiberglass, Stabil-D®
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- IRCCS Multimedica
Diabetic Foot Ulcer, Osteomyelitis
Diabetic Foot Osteomyelitis Treatment Using Gentamicin-loaded Calcium Sulfate-hydroxyapatite Biocomposite
The amputation risk is high when diabetic foot ulcers, complicated by osteomyelitis, fail to heal after non-surgical standard-of-care treatment. A new treatment regimen has been developed recently and has been proven feasible.
- Conditions
- Diabetic Foot Ulcer, Osteomyelitis, Diabetes Mellitus
- Trial name
- PRESERVE (NCT05316298)
- Where
- 10 sites in Netherlands
- Volunteers
- 182 people
- Sponsor
- University Medical Center Groningen
Cardiac Amyloidosis
Cardiac Amyloidosis Discovery Trial
This is a single center, diagnostic clinical trial in which the investigators aim to prospectively validate a deep learning model that identifies patients with features suggestive of cardiac amyloidosis, including transthyretin…
- Trial name
- NCT06469372
- Testing
- Cardiac amyloidosis deep learning model
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Pierre Elias
Chemotherapy Induced Peripheral Neuropathy
Self-applied taVNS for CIPN
The purpose of this study is to determine the feasibility of using a portable device at home to self-administer transcutaneous auricular vagus nerve stimulation (taVNS).
- Trial name
- NCT07596030
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Miami
Diabetes Mellitus, Type 1
Influence of Diabetic Neuropathy on Activation of Brown Adipose Tissue
Influence of diabetic neuropathy on cold induced brown adipose tissue in type 1 diabetic patients.
- Trial name
- DIA-BAT (NCT03695731)
- Testing
- cold induced activation of brown adipose tissue
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Doctor Giacomo Gastaldi
Painful Diabetic Neuropathy
A Trial to Investigate Safety and Efficacy of SPM927 in Painful Diabetic Neuropathy
The primary purpose is to investigate the safety and efficacy of SPM927 in patients with Painful Diabetic Neuropathy
- Trial name
- NCT00861445
- Testing
- SPM927/Lacosamide
- Volunteers
- 119 people
- Sponsor
- UCB Pharma
Diabetic Foot, Neuropathic Foot Ulcer
Application of S26E for Diabetic Foot Ulcer Healing
A randomized, controlled open-label, parallel group study to examine the effectiveness of a local application of the kalahari melon (Citrullus lanatus) seed oil for the healing of non-infected diabetic foot ulcers.
- Conditions
- Diabetic Foot, Neuropathic Foot Ulcer, Chronic Diabetic Ulcer of Left Foot (Diagnosis), Chronic Diabetic Foot Ulcer of Right Foot
- Trial name
- NCT04186377
- Testing
- Standard-of-care for neuropathic/neuroischemic diabetic foot ulcers, S26E
- Where
- Greece
- Volunteers
- 5 people
- Sponsor
- National and Kapodistrian University of Athens
Carpal Tunnel Syndrome (CTS)
Streamlining Care for Patients With Compression Neuropathies: The Carpal Tunnel Plus Pathway
The goal of this clinical trial is to assess the impact of a new care pathway (the Carpal Tunnel Plus Pathway) in patients with carpal tunnel syndrome. The main questions it aims to answer are: 1.
- Trial name
- CTS+ Pathway (NCT06717477)
- Testing
- Changes to the care pathway for carpal tunnel syndrome (The Carpal Tunnel Plus Pathway)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of British Columbia
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.