Clinical trials: Neuropathy (Disorder)
Neuropathy, Neuropathy, Painful
MultiSENSory Stimulation to TArgeT Sensory Loss and ChronIc Pain in NeurOpathic PatieNts
Neuropathy is a costly and disabling health issue, which consists of a degeneration of the peripheral nerves. Even though the causes may be different, such as diabetes or amputation, the consequences for neuropathic patients are…
- Conditions
- Neuropathy, Neuropathy, Painful, Sensory Neuropathy, Diabetic Neuropathies
- Trial name
- SENSATION (NCT05483816)
- Testing
- VR+TENS
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
Carpal Tunnel Syndrome
Topical Cannabidiol for Treating Carpal Tunnel Syndrome
The Purpose of this study is to assess the safety and efficacy of Cannabidiol on treatment of Carpal Tunnel Syndrome.
- Trial name
- NCT06108349
- Testing
- Cannabidiol
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Cardiac Amyloidosis
REVEAL - Research With I-124 EVuzamitide to Elucidate Cardiac AmyLoidosis
The purpose of this multicenter, open-label, single-arm, single-dose study is to assess the sensitivity and specificity of I-124 evuzamitide for the diagnosis of cardiac amyloidosis compared to current clinical standards for…
- Trial name
- REVEAL (NCT06788535)
- Testing
- I-124 evuzamitide
- Where
- 20 sites in United States
- Volunteers
- 204 people
- Sponsor
- Sharmila Dorbala
Diabetes Mellitus Foot Ulcer
Platelet Rich Plasma and Autologous Fat Graft for Diabetic Ulcer
Conventional management of diabetic ulcers is associated with slow healing, high costs and repeated trips to clinic. Stem cells contained in fat grafts can differentiate into pro-healing cells and release growth factors with…
- Trial name
- NCT03085550
- Testing
- Fat grafting, Fat grafting + platelet rich plasma
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University College, London
Piriformis Syndrome
Interfascial Hydrodissection Added to Ultrasound-Guided Piriformis Injection for Piriformis Syndrome
The gluteus maximus overlies the piriformis muscle and forms a broad fascial interface with it. Restricted movement, increased tension, or adhesions between these tissue layers may contribute to persistent buttock pain in…
- Trial name
- NCT07813455
- Testing
- Ultrasound-Guided Piriformis Injection, Ultrasound-Guided Interfascial Hydrodissection, Standardized Home-Based Piriformis Stretching Program
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Polyneuropathy
Asian Study on Cilostazol Effectivity in Neuropathies of Diabetes Mellitus Type 2-A Pilot Study in the Philippines
To describe if there are differences in the subjective, objective and electrophysiologic parameters of diabetic polyneuropathies at baseline, four (4) weeks, eight (8) weeks, and twelve (12) weeks after Cilostazol therapy.
- Trial name
- ASCEND (NCT01076478)
- Testing
- Cilostazol
- Where
- Philippines
- Volunteers
- 47 people
- Sponsor
- Otsuka Pharmaceutical, Inc., Philippines
Diabetic Foot, Regional Anesthesia
Efficacy of Continuous Sciatic Nerve Block in Diabetic Foot Patients
Patients who underwent surgery for diabetic foot were divided into three groups: sciatic nerve block (Group B), continuous nerve catheter (Group C) .
- Conditions
- Diabetic Foot, Regional Anesthesia, Catheter Blockage, Wound Heal
- Trial name
- NCT04212325
- Testing
- Group C (Continuous sciatic nerve block), Group S (sciatic nerve block)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gulhane School of Medicine
Diabetes Mellitus, Diabetic Autonomic Neuropathy
Inspiratory Muscle Training in Patients With Autonomic Neuropathic
This study describes a controlled randomized clinical trial to evaluate the effect of inspiratory muscle training in patients with diabetic autonomic neuropathy.
- Trial name
- NCT00752440
- Testing
- Inspiratory muscle training (IMT)
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Neuropathy
Collection of Demographic, Clinical, and Instrumental Data of Patients With Peripheral Neuropathy Including Neurological Examination Data, Peripheral Nerve Conduction Analysis, and Nerve Electromyography and Ultrasound).
The study involves recording personal, clinical, and instrumental information. The acquisition of the above-mentioned personal and clinical information will be carried out in conjunction with the usual follow-up visits scheduled…
- Trial name
- REG-NP (NCT07437989)
- Testing
- peripheral neuropathies
- Where
- Italy
- Volunteers
- 4,000 people
- Sponsor
- Casa di Cura Dott. Pederzoli
Diabetic Foot Ulcer
Trial of Dehydrated Human Amnion/Chorion Membrane (dHACM) In the Management of Diabetic Foot Ulcers
The objective of this study is to evaluate the percentage of patients with complete diabetic foot ulcer (DFU) closure following up to 12 weeks of treatment with either dehydrated human amnion/chorion membrane (dHACM) plus…
- Trial name
- NCT01693133
- Testing
- Standard of Care: Moist Wound Therapy and Offloading, EpiFix plus Standard of Care
- Where
- 20 sites in United States
- Volunteers
- 132 people
- Sponsor
- MiMedx Group, Inc.
Hereditary Sensory Neuropathy Type I
Hereditary Sensory Neuropathy Serine Trial
This is a randomised double-blind placebo-controlled trial of L-serine in Hereditary Sensory Neuropathy type 1 (HSN1) due to variants in SPTLC1/2 gene.
- Trial name
- SENSE (NCT06113055)
- Testing
- L-serine
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University College, London
Glaucoma, Macular Degeneration
BCI and Evaluation of Visual and Task Performance in Subjects With Eye Diseases
The purpose of this research study is to better understand the impact of visual impairment caused by different eye diseases on the ability to perform daily activities and compare it to that in patients without eye diseases.
- Conditions
- Glaucoma, Macular Degeneration, Glaucoma Suspect, Optic Neuropathy
- Trial name
- NCT03318549
- Testing
- Visual Performance tests, Brain-computer interface
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cardiac Amyloidosis
Artificial Intelligence Guided Echocardiographic Screening of Rare Diseases (EchoNet-Screening)
Despite rapidly advancing developments in targeted therapeutics and genetic sequencing, persistent limits in the accuracy and throughput of clinical phenotyping has led to a widening gap between the potential and the actual…
- Trial name
- NCT05139797
- Testing
- EchoNet-LVH screening for cardiac amyloidosis
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Cedars-Sinai Medical Center
Piriformis Syndrome
Effects of Global Hip Versus Isolated Abductors Strengthening Exercises in Patients Withsecondary Piriformis Syndrome
The study will be a randomized controlled trial. Twenty-four subjects will be assigned randomly by using the lottery method into two groups.
- Trial name
- NCT05848063
- Testing
- Global hip muscles strengthening exercises, Hip abductors strengthening exercises
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Diabetic Foot Ulcer
Cellular Reprogramming-Enhanced Skin Grafting for Diabetic Foot Ulcers
Diabetic foot ulcer is one of the refractory wounds and always poses many challenges in clinical practice. This study was conducted to have a prospective, randomised, controlled study compare the safety and efficacy of the…
- Trial name
- CREST-DFU (NCT02070835)
- Testing
- autologous skin cell, skin graft
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Hu Zhicheng
Carpal Tunnel Syndrome
Carpal Tunnel Syndrome - Randomized Clinical Trial Evaluating Effectiveness of Ultrasound in Corticosteroid Injection
The objective of this study is to evaluate the efficacy of ultrasound guided corticosteroid injection in reducing symptoms caused by carpal tunnel syndrome.
- Trial name
- STC-EI (NCT02036125)
- Testing
- Ultrasound, methylprednisolone
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Université de Sherbrooke
Chemotherapy-induced Peripheral Neuropathy (CIPN)
Effectiveness of Video-Based Movement Analysis-Guided Personalized Rehabilitation in Patients With Chemotherapy-Induced Peripheral Neuropathy (CIPN)
This study aims to quantify motor control abnormalities using video-based movement analysis in patients with chemotherapy-induced peripheral neuropathy (CIPN) and to evaluate the effectiveness of an analysis-guided personalized…
- Trial name
- NCT07714278
- Testing
- ReMap, Usual Care
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Bundang Hospital
Carpal Tunnel Syndrome, Carpal Tunnel
Are There Differences in Postoperative Pain Between Bupivacaine and Lidocaine for Carpal Tunnel Release?
The goal of this clinical trial is to compare the use of bupivacaine and lidocaine as local anesthetics in carpal tunnel release surgery.
- Trial name
- NCT05697276
- Testing
- Lidocaine, Bupivacain
- Where
- Argentina
- Volunteers
- 82 people
- Sponsor
- Hospital Italiano de Buenos Aires
Diabetic Foot Ulcer, Diabetic Foot
Treatment of Chronic Diabetic Foot Ulcers by Minimally Invasive Surgery
Despite the development of the control of DM and the great interest for the complications of the disease, even today the diabetic foot represents a challenge for the orthopaedic surgeon.
- Conditions
- Diabetic Foot Ulcer, Diabetic Foot, Diabetic Foot Infection, Diabetic Foot Ulcer Neuropathic
- Trial name
- DiabeticMIS1 (NCT03010215)
- Testing
- Distal Metatarsal Minimally invasive Osteotomy (DMMO)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Padova
Diabetic Foot Ulcer, Diabetic Neuropathy Peripheral
Patients With Diabetic Neuropathy Who Receive Physiotherapy Treatment Will Have a Decrease in Diabetic Foot Ulcers
This study evaluates the effects of a physiotherapy protocol (manual therapy and exercise) in the prevention of diabetic foot ulcers in patients with diabetic neuropathy.
- Trial name
- NCT03725917
- Testing
- Physiotherapy protocol
- Where
- Spain
- Volunteers
- 143 people
- Sponsor
- Universidad Complutense de Madrid
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