Clinical trials: Neuropathy (Disorder)
Erbs Palsy
Effects of Scapular Mobilization on Upper Limb Function
Erb's Palsy is a physical impairment resulting from an injury to the upper trunk of the brachial plexus and is associated with paralysis of the upper limb.
- Trial name
- NCT06198218
- Testing
- Scapular mobilization, Conventional physical therapy program
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Chemotherapy-induced Peripheral Neuropathy
Exercises for Patients Who Were Receiving Chemotherapy
To evaluate the effect of lower extremity strengthening and balance exercises on balance, quality of life and neuropathic pain of the cancer patients receiving neurotoxic chemotherapy.
- Trial name
- NCT03798379
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hitit University
Carpal Tunnel Syndrome
Comparison of Long-term Outcomes Following Endoscopic or Open Surgery for Carpal Tunnel Syndrome
No randomized trials have compared long-term outcomes following endoscopic and open carpal tunnel release in patients with carpal tunnel syndrome (CTS).
- Trial name
- NCT01887145
- Testing
- Endoscopic surgery, Open surgery
- Volunteers
- 124 people
- Sponsor
- Region Skane
Dysautonomia, Familial, Baroreflex Failure Syndrome
Carbidopa for the Treatment of Excessive Blood Pressure Variability
The overall study objectives are to determine whether carbidopa (Lodosyn®) is safe and well tolerated and to assess whether it can inhibit catecholamine-induced paroxysmal hypertension and normalize or reduce the exaggerated…
- Trial name
- CarbiFD (NCT02553265)
- Testing
- Carbidopa Low-Dose, Carbidopa High-Dose
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- NYU Langone Health
Diabetic Foot Ulcers
Omnigen DFU Pilot Study
The Omnigen Pilot study aims to provide an evidence base for Omnigen as a treatment for Diabetic Foot Ulcers (DFU). It aims to achieve this by tailoring a regenerative therapy used for ocular surface repair to provide proactive…
- Trial name
- NCT03483467
- Testing
- Omnigen, Dummy Packaging
- Where
- 2 sites in United Kingdom
- Volunteers
- 31 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Chemotherapy-induced Peripheral Neuropathy
Role of Curcumin in Paclitaxel Induced PN
Paclitaxel induced peripheral neuropathy is the most common and serious side effect associated with Paclitaxel treatment in breast cancer patients receiving Paclitaxel.
- Trial name
- NCT05966441
- Testing
- Curcumin, Paclitaxel
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Bilateral Carpal Tunnel Syndrome (Diagnosis), Cardiac Amyloidosis
Early Screening for Cardiac Amyloid Using a History of Bilateral Carpal Tunnel Syndrome
Cardiac amyloidosis is a condition where abnormal protein deposits build up in the heart, making it stiff and causing it to work less effectively.
- Trial name
- NCT07580872
- Testing
- Technetium-99m Pyrophosphate (Tc-99m PYP) Scan
- Volunteers
- 139 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Painful Diabetic Neuropathy
Quantitative Assessment of Painful Diabetic Peripheral Neuropathy After High Frequency Spinal Cord Stimulation
Will participants with painful lower extremity diabetic peripheral neuropathy (DPN) that are treated with high frequency spinal cord stimulation (HF10 SCS) have improvements in lower extremity peripheral nerve function?
- Trial name
- NCT03769675
- Testing
- High Frequency Spinal Cord Stimulator
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Transthyretin Amyloidosis, Cardiomyopathy
Safety and Efficacy Study of Doxycycline/UrsoDeoxyCholicAcid on Disease Progression in ATTR Amyloidosis
The primary objective for this study is to evaluate the efficacy of doxycycline + ursodeoxycholic acid (UDCA) on disease progression in Transthyretin Amyloidosis (ATTR) subjects with cardiomyopathy with or without neuropathy.
- Trial name
- Dox/Urso (NCT02016365)
- Testing
- Doxycycline, Ursodeoxycholic acid
- Where
- 3 sites in Sweden
- Volunteers
- 55 people
- Sponsor
- Umeå University
Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients, Metastatic Colorectal Cancer (CRC)
Neuroprotective Potential of Cannabidiol (CBD) in Preventing Oxaliplatin (Ox)-Induced Neuropathy
This is a pilot, prospective, randomized study evaluating the feasibility and acceptability of incorporating hemp-derived cannabidiol (CBD) supplementation to prevent oxaliplatin-induced peripheral neuropathy (OIPN) in patients…
- Conditions
- Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients, Metastatic Colorectal Cancer (CRC), Peripheral Neuropathy Due to Chemotherapy
- Trial name
- NCT07167446
- Testing
- Cannabidiol (CBD), oxaliplatin-based chemotherapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Fox Chase Cancer Center
Neuropathic Pain
Effects of Smoked Marijuana on Neuropathic Pain
To determine if smoking marijuana will reduce neuropathic pain without causing too much drowsiness or feeling "too dopey".
- Trial name
- NCT00254761
- Testing
- Cannabis
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Center for Medicinal Cannabis Research
Carpal Tunnel Syndrome
Efficacy of Steroid Injection in Patients With Bifid Median Nerve Diagnosed Carpal Tunnel Syndrome
Various median nerve anatomical variations have been reported in the literature.One of these is the bifid median nerve.Due to its relatively higher cross-sectional area, it can facilitate compression of the median nerve in the…
- Trial name
- NCT06599086
- Testing
- 2 cc:(1 cc betamethasone dipropionate+1cc physiological saline)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Yunus Burak Bayır
Diabetic Foot Ulcer, Diabetic Foot
DFC 004 Biomarkers for Active Diabetic Foot Ulcers
This study is a platform study designed to efficiently test multiple biomarkers to identify diabetic foot ulcers (DFUs) with a higher potential for healing versus not healing that ultimately could be applied at the point of care…
- Conditions
- Diabetic Foot Ulcer, Diabetic Foot, Diabetes
- Trial name
- NCT06104969
- Where
- 9 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- University of Michigan
Carpal Tunnel Syndrome
The Effect of Platelet Rich Plasma for Carpal Tunnel Syndrome
The platelet rich plasma (PRP) is a new and potential treatment for patients with kinds of musculoskeletal disorders. Although few studies have showed beneficial effect of PRP for regeneration of peripheral neuropathy in animal…
- Trial name
- NCT02539186
- Testing
- platelet rich plasma, splint
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Vestibular Abnormality, Vestibular Nerve Disorders
Test-Retest Reliability of oVEMP's Across Different Electrode Montages
"Test-Retest Reliability of ocular vestibular evoked myogenic potentials (oVEMPs) across different electrode montages." The purpose of this project is to compare the response characteristics of the ocular vestibular evoked…
- Trial name
- NCT03251586
- Testing
- oVEMP - infra-orbital electrode montage, oVEMP - belly-tendon electrode montage
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Foot Ulcer, Diabetes Mellitus
Efficacy Of CACIPLIQ20 On Diabetic Ulcers In Patients Wearing An Nonremovable, Windowed, Fiberglass Cast Boot
CACIPLIQ20 is a nanopolymer engineered to mimic glycosaminoglycans such as heparan sulfates. Glycosaminoglycans are implied 1) in the stabilization of the micro-environment of cells, known as extracellular matrix, by binding to…
- Conditions
- Foot Ulcer, Diabetes Mellitus, Diabetic Neuropathy
- Trial name
- DIAPLIQ (NCT01474473)
- Testing
- CACIPLIQ20 and Nonremovable, Windowed, Fiberglass Cast Boot
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Organ, Tissue, Regeneration, Repair and Replacement
Amyloidosis Cardiac, Heart Failure
Screening, Characterization, and Longitudinal Follow-up of Patients With Cardiac Amyloidosis
Cardiac amyloidosis is a progressive disorder caused by extracellular deposition of amyloid fibrils in the heart, leading to heart failure and impaired cardiac function.
- Conditions
- Amyloidosis Cardiac, Heart Failure, Cardiac MRI, Spectroscopic Analysis
- Trial name
- NCT07577466
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Foot Ulcer, Diabetic
Evaluation of a New Device "Orthèse Diabète" in the Healing of Foot Ulcers in Diabetic Patients
Multi-center trial, randomized in 2 parallel groups, open label, with a blinded adjudication committee (PROBE methodology), comparing "Orthèse Diabète" with "conventional" removable devices in terms of healing of ulcers.
- Trial name
- ORTHODIAB (NCT01956162)
- Testing
- Orthèse Diabète, "Conventional" Device
- Where
- France
- Volunteers
- 118 people
- Sponsor
- Proteor Group
Carpal Tunnel Syndrome
Lipografting Versus Steroid Injections for Treatment of Carpal Tunnel Syndrome
This study applies the regenerative properties of autologous fat transfer to treat mild to moderate carpal tunnel syndrome in comparison to the current standard of care, corticosteroid treatment.
- Trial name
- NCT03722303
- Testing
- Fat Injection, Steroid Injection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Columbia University
Diabetic Peripheral Neuropathy
A Study Of The Analgesic (Pain-Relief) Effects Of Tanezumab In Adult Patients With Diabetic Peripheral Neuropathy
The purpose of this study is to determine the effectiveness and safety of the investigational drug, tanezumab, in adult patients with painful diabetic peripheral neuropathy.
- Trial name
- NCT01087203
- Testing
- Tanezumab
- Where
- 48 sites in United States
- Volunteers
- 73 people
- Sponsor
- Pfizer