Clinical trials: Neuropathy (Disorder)
Traumatic Brain Injury
Effects of Intranasal Nerve Growth Factor for Traumatic Brain Injury
Traumatic bain injury(TBI) remains a hidden epidemic involving individuals affected predominantly at a young age who in the most severe cases remain with permanent physical,psychological and cognitive deficits.This study will…
- Trial name
- NCT01212679
- Testing
- nerve growth factor, nomral saline
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Jinling Hospital, China
Breast Cancer
Identification of Chemotherapy-induced Peripheral Neuropathy
The main goal of this trial is to identify the optimal cut-off score of a Scoring System to discriminate between moderate to severe chemotherapy-induced peripheral neuropathy (CIPN) and no CIPN in breast cancer survivors…
- Trial name
- NEURO-BREAC (NCT07148336)
- Testing
- Symptom-based scoring system
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- University Hospital Schleswig-Holstein
Pain, Pain Syndrome
Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy
Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates…
- Conditions
- Pain, Pain Syndrome, Pain, Chronic, Chronic Pain
- Trial name
- NCT06071936
- Testing
- Adezunap (AP707)
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- Apurano Pharmaceuticals GmbH
Painful Diabetic Neuropathy
Safety, Tolerability & Pharmacokinetics Study of CNTX-6016 in Healthy Subjects and Subjects With PDN
A Phase 1b study to evaluate the safety, tolerability and pharmacokinetics of multiple ascending doses of CNTX-6016 in healthy subjects and a single cohort to evaluate painful diabetic neuropathy.
- Trial name
- NCT04857957
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Centrexion Therapeutics
Carpal Tunnel Syndrome
Acute Effect of Topical Menthol on Carpal Tunnel Syndrome
Topical menthol gels are classified 'topical analgesics' and are used to relieve pain of the musculoskeletal system. However, double-blind randomized controlled trials are lacking.
- Trial name
- IRMA (NCT01716767)
- Testing
- Menthol
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Research Centre for the Working Environment, Denmark
Organic, Including Symptomatic, Mental Disorders, Substance Use
Exploring the Comorbidity Between Mental Disorders and General Medical Conditions
Mental disorders have been shown to be associated with a number of general medical conditions (also referred to as somatic or physical conditions).
- Conditions
- Organic, Including Symptomatic, Mental Disorders, Substance Use, Schizophrenia, Mood [Affective] Disorders
- Trial name
- COMO-GMC (NCT03847753)
- Testing
- Organic Disorders, Substance Use Disorders, Schizophrenia Disorders
- Volunteers
- 5,940,299 people
- Sponsor
- University of Aarhus
Chronic Limb Threatening Ischemia
Transverse Tibial Transport for Chronic Limb-Threatening Ischemia (CLTI)
Chronic limb-threatening ischemia (CLTI) is a serious condition that happens when blood flow to the legs or feet is severely reduced.
- Trial name
- NCT07175129
- Testing
- Transverse Tibial Bone Transport, TrueLok Elevate
- Where
- United States
- Sponsor
- University Hospitals Cleveland Medical Center
Diabetic Neuropathies
Comparative Effects of Proprioceptive Training and Routine Physical Therapy on Diabetic Peripheral Neuropathy
This project will compare the effects of proprioceptive training with routine physical therapy intervention on improving balance and health-related quality of life in individuals with diabetic neuropathy.
- Trial name
- NCT05968131
- Testing
- Conventional Physical Therapy, Conventional Physical Therapy with Proprioceptive Training Exercises
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- University of Lahore
Diabete Mellitus, Diabetic Foot
Effect of Self- and Family Management of Diabetic Foot Ulcers Programs on Health Outcomes
Brief description: Diabetic foot ulcer (DFU) is described as a full-thickness lesion appearing at the skin of the foot along with infection, destruction of tissues due to neuropathy and/or peripheral artery disease (PAD) in…
- Trial name
- NCT03909802
- Testing
- Self-and family management of diabetic foot ulcers programs, Usual care
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Universitas Muhammadiyah Yogyakarta
Facial Palsy, Neuropathy
Stellate Gnaglion Block in Refractory Bell's Palsy
Idiopathic facial nerve palsy (Bell's palsy) is caused by damage to the facial nerve at any site of the peripheral branches after the facial nucleus.Stellate ganglion block is inteneded to increase blood flow and promotes nerve…
- Trial name
- NCT05094245
- Testing
- Stellate Ganglion Block Group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Carpal Tunnel Syndrome
Cost Information on Carpal Tunnel Syndrome Treatment Decisions
The purpose of this study was to determine whether the provision of societal cost information affects patients' decisions whether or not to undergo surgical management in carpal tunnel syndrome, using a hypothetical scenario.
- Trial name
- NCT03880812
- Testing
- Societal cost
- Where
- 6 sites in United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Carpal Tunnel Syndrome
Comparative Study of Two Incision vs. Mini Open Carpal Tunnel Release
Hand surgeons have many options to perform carpal tunnel release surgery. Some surgeons believe that techniques are best kept simple: a mini-open incision that allows adequate exposure of the transverse carpal ligament (TCL)…
- Trial name
- NCT05325567
- Testing
- Mini open incision CTR
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Louisville
Type I Diabetes Mellitus With Ulcer, Type II Diabetes Mellitus With Ulcer
Safety Study of Stem Cells Treatment in Diabetic Foot Ulcers
Diabetes Mellitus (DM) can be regarded as one of the "epidemics" of the western world. DM contributes to severe morbidity and mortality due to damage in the target organs (neuropathy, vasculopathy, nephropathy, retinopathy).
- Trial name
- NCT01686139
- Testing
- ABMD-MSC
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Sheba Medical Center
Diabetic Neuropathy, Arthritis
Effect of Holofiber Socks and Bedding on Pain and Quality of Sleep in Subjects With Chronic Foot Pain
This study is designed to assess the effects of socks and bedding materials on foot pain, the level of blood oxygen existing in the feet and quality of sleep in subjects who have chronic foot pain from either diabetic neuropathy…
- Conditions
- Diabetic Neuropathy, Arthritis, Peripheral Arterial Disease, Plantar Fasciitis
- Trial name
- NCT00458497
- Testing
- Holofiber fabric, PET fabric
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Southern California Institute for Research and Education
Fibromyalgia, Painful Diabetic Peripheral Neuropathy
Examination of Pregabalin Access for Treatment of Indicated Pain Disorders: the ExPAND Study
The investigators hypothesize that fibromyalgia (FM) and painful diabetic peripheral neuropathy (pDPN) patients with access restrictions on pregabalin will lead to higher healthcare resource use and cost compared to patients…
- Trial name
- NCT01280747
- Testing
- prior authorization, no prior authorization
- Where
- 17 sites in United States
- Volunteers
- 42 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Erbs Palsy
Intensive Therapy of Shoulder External Rotators in Erb's Palsy
Erb's palsy is a common neurological injury occurs at the time of birth. It causes injury to the upper trunk nerve root c5-c6, i.e., supply is around shoulder and muscles of forearm and these nerves network from the spine and…
- Trial name
- NCT04979689
- Testing
- Intensive physical therapy, Non intensive physical therapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Familial Dysautonomia (Riley-Day Syndrome), Hereditary Sensory and Autonomic Neuropathies
The Natural History of Familial Dysautonomia
The study will collect clinical information from patients with FD and allow them to give blood to help develop biological markers of the disease to aid diagnosis and treatment.
- Conditions
- Familial Dysautonomia (Riley-Day Syndrome), Hereditary Sensory and Autonomic Neuropathies, Hereditary Sensory and Autonomic Neuropathy 3
- Trial name
- NCT03920774
- Where
- 2 sites in United States, Israel
- Volunteers
- 400 people
- Sponsor
- NYU Langone Health
Carpal Tunnel Syndrome
Patient Satisfaction With Pain Relief After Ambulatory Hand Surgery
Adequate pain relief has been a priority of the Joint Commission and is featured on national inpatient surveys such as the H-CAHPS.
- Trial name
- NCT01588158
- Testing
- Acetaminophen, Vicodin
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Massachusetts General Hospital
Charcot-Marie-Tooth Disease, Hereditary Motor and Sensory Neuropathies
Ascorbic Acid Treatment in CMT1A Trial (AATIC)
Charcot-Marie-Tooth type IA (CMT1A) is the most prevalent hereditary peripheral neuropathy. Demyelination of peripheral nerves is the hallmark of CMT1A.
- Trial name
- AATIC (NCT00271635)
- Testing
- ascorbic acid
- Where
- Netherlands
- Volunteers
- 13 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
ANCA Associated Vasculitis
the Application of Diffusion Tensor Imaging in the Evaluation of Peripheral Neuropathy in ANCA Associated Vasculitis
1. Include qualified 50 ANCA-associated vasculitis(AAV) patients; and the first 27 patients will be divided into 3 groups with different diffused tension image (DTI) parameters and to choose the best strategy； 2.
- Trial name
- NCT04923074
- Testing
- diffusion tensor imaging(DTI) evaluation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
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