Clinical trials: Neuropsychiatric Disorders, active
Toxoplasmosis in Neuropsychiatric Disorders
Toxoplasma Gondii Seroprevalence Among Children With Some Neuropsychiatric Disorders
Toxoplasma gondii is recognized as being involved in the etiology of various psychotic disorders including epilepsy and ADHD (Markovitz et al.,2015).
- Trial name
- NCT06980298
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Depressive Syndrom
Real-World NeuroModulate: Investigating Non-Invasive Brain Stimulation for Neuropsychiatric Disorders at TUM
In this study, patients diagnosed with a depressive syndrome and with a clinical indication for treatment will receive an acute course of transcranial magnetic stimulation (TMS).
- Trial name
- NCT07420322
- Testing
- iTBS Treatment
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Mild Cognitive Impairment, Mild Dementia
Assessing Cognitive Decline at Home
Neuropsychiatric symptoms (NPS) refer to a range of mental and emotional issues that can be observed through how patients move, perform daily tasks, and express feelings on their faces.
- Conditions
- Mild Cognitive Impairment, Mild Dementia, Dementia Alzheimers, Dementia
- Trial name
- NCT06704971
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Stanford University
Mild Cognitive Impairment, Alzheimer Disease
Music Therapy for Patients With Alzheimer's Disease
This study is designed to assess the feasibility that individualized reminiscence-based virtual music therapy sessions can enhance autobiographical memory, mood, and cognition in patients with mild cognitive impairment (MCI) or…
- Trial name
- NCT05151562
- Testing
- Virtual Music Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
PARKINSON DISEASE (Disorder)
Local Field Potential Correlates of Neuropsychiatric Symptoms in Parkinson's Disease
This prospective observational cohort study aims to investigate whether intracranial Local Field Potentials (LFPs) recorded from implanted Deep Brain Stimulation (DBS) devices are associated with neuropsychiatric symptoms in…
- Trial name
- LFP-in-PD (NCT07633379)
- Where
- 2 sites in China, United Kingdom
- Volunteers
- 20 people
- Sponsor
- King's College London
Medication Refractory Epilepsy Patients With Electrodes Already Implanted Based on Clinical Criteria for Standard Monitoring
Model-based Electrical Brain Stimulation
Neuropsychiatric disorders are a leading cause of disability worldwide with depressive disorders being one of the most disabling among them.
- Trial name
- NCT05327387
- Testing
- model-based electrical brain stimulation
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- University of Southern California
Neuropsychiatric Syndrome, Autism Spectrum Disorder
Nature and Animal-assisted Activities
Neuropsychiatric impairments in young adults are common and can involve social withdrawal, and difficulties in receiving support from healthcare and municipal social care services.
- Trial name
- NCT06431126
- Testing
- Nature and animal-assisted activities
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Kronoberg County Council
Multiple Sclerosis, Alzheimer's Disease
PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases
The specific aims of the study are: Primary: To determine the presence and regional distribution of microglial activation, as assessed by Fluorine-18 (18F) labeled "Peripheral Benzodiazepine Receptor 06" (PBR06) -PET, in subjects…
- Trial name
- MAPET (NCT02649985)
- Testing
- [F-18]PBR06, [C-11]PBR28
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Neurocognitive Disorders
Personalized Interventions Via Health Portraits in Mild Behavioral Impairment
The incidence of MBI and the probability of progression to dementia are high. Early detection and intervention have important clinical significance to reduce the occurrence of dementia, delay the progression of dementia and…
- Trial name
- NCT06416514
- Testing
- Personalized intervention
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fujian Provincial Hospital
Psychiatric Disorder, Memory Disorders
Neural Correlates of Psychiatric Disorders
This ClincialTrials.gov record originally corresponded to the protocol approved under IRB # 202370. The study was expanded to include stimulation and recordings approved under new IRB #211037.
- Trial name
- NCT04725409
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt University Medical Center
Acquired Brain Injury (Including Stroke)
Neuropsychiatric Outcomes and Disrupted Sleep Following Acquired Brain Injury
The two most common causes of brain injury are stroke and trauma. Both sleep and mental health problems are common after brain injury; we will investigate whether there is a relationship between poor sleep quality and worse…
- Trial name
- NODS (NCT07215195)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Oxford
Neurodevelopmental Disorders, Autism Spectrum Disorder
Patterns of Neurodevelopmental Disorders
The purpose of this study is to systematically evaluate the results of medical investigations to identify symptom and biological patterns and common etiologies of neurodevelopmental disorders.
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder, Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infection, Pediatric Acute-Onset Neuropsychiatric Syndrome
- Trial name
- NCT06213090
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Richard Frye
Chronic Fatigue Syndrome
Blood-Brain Barrier Integrity and Immune Dynamics in Neuropsychiatric Sequelae of Post-SARS-CoV-2 Onset ME/CFS Versus Pre-Pandemic ME/CFS Patients
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex chronic illness impacting multiple body systems and characterized by activity-limiting fatigue and post exertional symptom exacerbation, affecting over 3.5…
- Trial name
- MECFS BBB (NCT07256795)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins University
Post-acute Infectious Syndrome (PAIS), Post-COVID-19 Condition (PCC or Long COVID)
Post-acute Infectious Syndrome - Aripiprazole Symptom Evaluation (PAIS-AriSE)
Post-acute infectious syndrome (PAIS), including post-COVID-19 condition (PCC or Long COVID), can develop after an infection and may cause persistent symptoms such as fatigue, problems with memory and concentration ("brain fog")…
- Trial name
- PAISE-AriSE (NCT07714213)
- Testing
- Aripiprazole (low-dose, 1mg)
- Where
- Germany
- Volunteers
- 138 people
- Sponsor
- Christiana Franke
Bipolar Disorder (BD), Schizophrenia Disorders
Creating a Global Research Database That Connects Genetic Information and Long-term Health Data to Improve Personalized Treatment for People With Serious Mental Illness
This observational study aims to provide new insights into the nature and classification of severe mental illness and dementias that in time should help improve diagnostic practise, and enable the development of new and improved…
- Conditions
- Bipolar Disorder (BD), Schizophrenia Disorders, Major Depressive Diorder, Dementia
- Trial name
- GlobalMinds (NCT06641726)
- Testing
- Not applicable- observational study
- Where
- United Kingdom
- Volunteers
- 50,000 people
- Sponsor
- Akrivia Health
Stroke, Fatigue Symptom
Sleep-Disordered Breathing in the Acute Phase After Stroke and Neuropsychiatric Outcomes
In people who have had a stroke or a transient ischemic attack (TIA), it is common to have problems with breathing patterns during sleep, particularly a condition called obstructive sleep apnea.
- Conditions
- Stroke, Fatigue Symptom, Obstructive Sleep Apnea, Sleep Disordered Breathing (SDB)
- Trial name
- NCT06811948
- Where
- Sweden
- Volunteers
- 340 people
- Sponsor
- Blekinge County Council Hospital
PTSD, Post Traumatic Stress Disorder
Determining the Right Acupuncture for Good Recovery Over Neuropsychiatric Trauma
This study seeks to verify that a specific acupuncture treatment is effective at reducing symptoms of neuropsychiatric trauma found in those diagnosed with Post-Traumatic Stress Disorder (PTSD).
- Conditions
- PTSD, Post Traumatic Stress Disorder, Acupuncture
- Trial name
- NCT05516862
- Testing
- Dragons acupuncture, Dragons acupressure
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Paul Crawford
PANS, Pediatric Acute-Onset Neuropsychiatric Syndrome
Biomarkers for Diagnosis and Treatment Response in Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)
Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) is a complex neuropsychiatric disorder characterized by the abrupt onset of symptoms and currently diagnosed mainly on clinical criteria, as reliable diagnostic biomarkers…
- Trial name
- BIOMA-PANS (NCT07718958)
- Testing
- Psycodiagnostic evaluation, Polysomnography, 1H-NMR analysis
- Where
- 5 sites in Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Dementia With Lewy Bodies
Ambroxol in New and Early DLB, A Phase IIa Multicentre Randomized Controlled Double Blind Clinical Trial
This is a confirmatory investigational medicinal product (IMP) study to investigate the effects on cognition, functional decline and on neuropsychiatric symptoms of the Glucocerebrosidase (GCase) enhancing chaperone ambroxol in…
- Trial name
- ANeED (NCT04588285)
- Testing
- Ambroxol
- Where
- 8 sites in Norway
- Volunteers
- 180 people
- Sponsor
- Helse Fonna
Major Depressive Disorder
Targeting Specific Brain Networks to Treat Specific Symptoms in Depression
Repetitive transcranial magnetic stimulation (rTMS) is a way of non-invasively stimulating specific brain networks and is an established treatment for Major Depressive Disorder (MDD).
- Trial name
- NCT05523817
- Testing
- Intermittent Theta Burst Stimulation (iTBS)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital