Clinical trials: Neuropsychiatric Symptoms
Old Age, Frailty
Activity and Health in Nursing Homes
There is expected to be an increased need for full time nursing homes as the increase in number of older adults increases and the rate of dementia diagnosis happens simultaneous with the decrees of healthcare personnel the years…
- Trial name
- NCT05037084
- Testing
- no intervention
- Where
- Norway
- Volunteers
- 1,123 people
- Sponsor
- Norwegian University of Science and Technology
Smoking Cessation
Assessing Neuropsychiatric Symptoms Including Depression, Anxiety, Irritability, and Suicidal Thoughts or Behavior in Subjects Quitting Smoking on Varenicline Tartrate or Placebo
Study objective is to compare neuropsychiatric adverse events in subjects treated with varenicline or placebo in a controlled setting where both groups are experiencing nicotine withdrawal.
- Trial name
- NCT00749944
- Testing
- varenicline
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- Pfizer
Pediatric Cancer
OmegaChild - Omega-3 Supplementation to Children Previously Treated for Cancer
The purpose of this study is to find an optimal dose of omega-3 that can be given to children who have completed cancer therapy.
- Trial name
- OmegaChild (NCT02134600)
- Testing
- Omega-3 enriched fruit juice
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Per Kogner
Dementia, Alzheimer's Disease
Volunteers Adding Life in Dementia: VALID
Older adults with Alzheimer's disease and other forms of dementia frequently develop challenging neuropsychiatric symptoms (NPS) as a result of their illness.
- Trial name
- VALID (NCT01715181)
- Testing
- Volunteer visits
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Queen's University
Alzheimer's Disease, Alzheimer Dementia (AD)
Standardizing Care for Neuropsychiatric Symptoms and Quality of Life in Dementia
The object of this study to evaluation an Integrated Care Pathway (ICP) to treat Aggression and Agitation in Alzheimer's disease (AD-AA).
- Conditions
- Alzheimer's Disease, Alzheimer Dementia (AD), Aggression
- Trial name
- StaN (NCT03672201)
- Testing
- Non-Pharmacological Intervention, Pharmacological Intervention
- Where
- 6 sites in Canada
- Volunteers
- 187 people
- Sponsor
- Centre for Addiction and Mental Health
Wound Care, Pain
The Pain Reduction Using Immersive Virtual Reality During Wound Care Evaluation Study at Maimonides (PRISM) - Pilot Study
This study will test whether immersive virtual reality (iVR) can reduce pain and discomfort during wound care for residents living in long-term care (LTC).
- Conditions
- Wound Care, Pain, Neuropsychiatric Symptoms
- Trial name
- PRISM (NCT07447830)
- Testing
- Rendever Immersive Virtual Reality Platform
- Where
- 2 sites in Canada
- Volunteers
- 25 people
- Sponsor
- McGill University
Pain, Ketamine Adverse Reaction
Cardiovascular Safety After Continuous Ketamine Infusion
Observational study that evaluate the cardiovascular and neuropsychiatric side effects of ketamine analgesic infusions for acute pain
- Conditions
- Pain, Ketamine Adverse Reaction, Postoperative Pain
- Trial name
- NCT03979105
- Testing
- Ketamine
- Where
- 2 sites in Colombia
- Volunteers
- 300 people
- Sponsor
- Universidad de Antioquia
Dementia, Neurocognitive Disorders
Effectiveness and Cost-Effectiveness of Cognitive Stimulation Therapy - Spain (CST-ES) in People Living With Dementia
This study aims to evaluate the effectiveness and cost-effectiveness of CST-ES, the Spanish adaptation of Cognitive Stimulation Therapy (CST), to improve cognition and quality of life in people with mild to moderate dementia.
- Conditions
- Dementia, Neurocognitive Disorders, Mild Cognitive Impairment
- Trial name
- NCT06372002
- Testing
- Cognitive Stimulation Therapy (CST)
- Where
- 46 sites in Spain
- Volunteers
- 683 people
- Sponsor
- Instituto de Mayores y Servicios Sociales (IMSERSO)
Dementia, Behavioural and Psychiatric Symptoms of Dementia
Effect of Soundscape on People With Dementia.
In the last few decades, insights into the impact of the sonic environment on persons have grown to include not only the adverse effects of extensive mechanical noise but also the beneficial effects of a well-designed sonic…
- Trial name
- NCT04809545
- Testing
- Acusticare, Treatment as usual
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- University Health Network, Toronto
Alzheimer's Disease (Incl Subtypes), Depressive Symptoms
Beyond Listening: A Music-based Intervention
Study will be conducted to determine if caregivers who use music at home will feel less burden and whether the person they are caring for will demonstrate decreased symptoms of dementia.
- Trial name
- NCT04840173
- Testing
- Music
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- MJHS Institute for Innovation in Palliative Care
Dementia, Mild Cognitive Impairment
An Intervention to Reduce Discrepancy in Everyday Preferences
Dementia is a disabling, progressive major neurocognitive disorder. Although cognitive symptoms drive the diagnosis of dementia, neuropsychiatric symptoms (NPS), such as depression, agitation/aggression, and psychosis, are common…
- Trial name
- NCT03577418
- Testing
- Templated, clinician-facilitated intervention to align everyday living preferences assessment
- Where
- United States
- Sponsor
- Mclean Hospital
Pemphigoid, Pruritus
Pruritus and Pemphigoid in Nursing Home Patients
The primary objective of this observational study is to describe the prevalence of pruritus and pemphigoid in nursing home patients.
- Trial name
- SSENIOR (NCT02823067)
- Testing
- Blood sample
- Where
- Netherlands
- Volunteers
- 125 people
- Sponsor
- M.F. Jonkman
Mild Cognitive Impairment, Behavioral Symptoms
The Moderating Roles of Social Support, Coping Resources and Personality and Mediating Role of Self-esteem on the Impact of Cognitive Deficit on Neuropsychiatric Symptoms Among Persons With Mild Cognitive Impairment: A Mixed-method Sequential Explanatory Design
This is a sequential mixed study to test the hypothesized models with seven hypotheses of the relationship between cognitive deficit (subject and objective) and neuropsychiatric symptoms (NPS) among persons with mild cognitive…
- Trial name
- NCT04085107
- Testing
- Face-to-face interviews
- Where
- Hong Kong
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Anxiety Disorder, Head Injury
Neuropsychological Evaluation of Psychiatric and Neurological Patients
This study will allow researchers to use various types of tests to evaluate cognitive and sensory functions. These tests, referred to as "batteries" will evaluate attention, executive functions, general intellectual functioning…
- Conditions
- Anxiety Disorder, Head Injury, Mood Disorder, Schizophrenia
- Trial name
- NCT00001192
- Where
- 7 sites in United States, France and 1 more
- Volunteers
- 4,300 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Agitation, Alzheimer's Disease
Efficacy, Safety and Tolerability Study of AVP-923 (Dextromethorphan/Quinidine) for Treatment of Symptoms of Agitation in Participants With Alzheimer's Disease
The objectives of the study are to evaluate the safety, tolerability and efficacy of AVP-923 compared to placebo, for the treatment of symptoms of agitation in participants with Alzheimer's Disease (AD).
- Trial name
- NCT01584440
- Testing
- AVP-923-20, AVP-923-30
- Where
- 44 sites in United States
- Volunteers
- 220 people
- Sponsor
- Avanir Pharmaceuticals
CACNA1C
A Phase I/II, First-In-Human Trial to Evaluate the Safety, Tolerability, and Pharmacokinetic Activity to Prevent or Treat Neuropsychiatric Symptoms in Pediatric Subjects With Timothy Syndrome
The goal of this clinical trial is to learn if an antisense oligonucleotide (TS1-ASO) can safely treat and potentially prevent neuropsychiatric and neurodevelopmental symptoms in pediatric participants (age >2 months) with…
- Trial name
- TS1-ASO (NCT07600658)
- Testing
- TS1-ASO
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University