Clinical trials: Neuropsychology
Adjustment Disorders, Non-progressive Brain Injury
Does an Integrative Neuro-psychotherapy Program Foster the Adjustment in Depressed Stroke Patients? A Randomized Controlled Study.
This is an intervention study with patients after a non-progressive brain injury who suffer from depression. It will determine whether an integration of neuropsychological and psychotherapeutic techniques and an additional…
- Trial name
- NCT01039857
- Testing
- Neuropsychological Therapy, cognitive behavioral therapy, solution focused therapy, Integrative Neuro-Psychotherapy
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- University of Bern
Psychotic Disorders
Short-term Working Memory and Executive Training
Cognitive remediation (CR) therapies refer to a number of recent developments to use behavioural strategies to improve neurocognitive abilities and improve everyday functioning in mental disorders such as schizophrenia, bipolar…
- Trial name
- STExFx (NCT02168166)
- Testing
- Executive Function Training
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Queen's University
Feeding and Eating Disorders, Anorexia Nervosa
Cognitive Training for Patients With Eating Disorders
Eating disorders are severe mental illnesses, mainly affecting adolescent- and young adult women. The prognoses for eating disorders are relatively poor, and a large part of patients with these illnesses do not benefit from…
- Conditions
- Feeding and Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder
- Trial name
- TCRTRCT (NCT03808467)
- Testing
- Cognitive Remediation Therapy, Treatment as usual
- Where
- 3 sites in Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian University of Science and Technology
Parkinsons Disease (PD)
Non-invasive Diagnosis of Parkinson's Disease
This study will investigate new, non-invasive methods to help diagnose Parkinson's disease. Researchers will use advanced eye imaging (hyperspectral retinal photography and OCT), computerized memory and thinking tests, and voice…
- Trial name
- NCT07201610
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
Cognitive Impairment, Stroke
Addressing Problems in Managing Daily Tasks Due to Poststroke Cognitive Impairments
The purpose of this study is to investigate feasibility aspects of an intervention targeting problems in managing daily tasks due to mild-to-moderate poststroke cognitive impairments.
- Trial name
- NIOTI-stroke (NCT05829421)
- Testing
- Impairment-specific occupational therapy (OT) intervention
- Where
- 4 sites in Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Emma Ghaziani
Schizophrenia, Schizoaffective Disorder
Generalization of Training in Schizophrenia
This study examines whether patients with schizophrenia can benefit from a problem-solving training intervention and whether a work-related social skills training intervention leads to improvements in the patient's performance at…
- Trial name
- NCT00108199
- Testing
- Problem-Solving Training, Work-Related Social Skills Training
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Phenylketonuria
MRI Spectroscopy and Neuropsychological Functioning in Phenylketonuria
This is a study about the relationship of brain biomarkers with neuropsychological functioning in PKU. All participants will undergo MRI spectroscopy, will provide a blood specimen and will receive neuropsychological testing.
- Trial name
- NCT03097250
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Myofascial Trigger Points
A Clinical Observation on Neuropsychology and Electrophysiology in Headache Patinets With Myofascial Trigger Points
To study the clinical characteristics of headache patients with pericranial myofascial trigger points(MTrPs),and to explore the possible pathogenesis of MTrPs,investigators hope to find the possible electrical biomarkers for…
- Trial name
- NCT03082547
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Ictus, Severe Acquired Brain Injury
Personality Traits as a Variable in the Recovery of Patients With Acquired Brain Injury
This study aims to evaluate the potential effects of premorbid personality on the short- and long-term global cognitive recovery in patients with severe acquired brain injury (sABI) or stroke.
- Conditions
- Ictus, Severe Acquired Brain Injury, sABI
- Trial name
- NCT07119827
- Testing
- Motor, cognitive and psychological assessment
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Universita di Verona
Suspected Typical Alzheimer's Disease (AD), Suspected Atypical Alzheimer's Disease (AD)
VIdeo Telehealth in ALzheimer's: NeuroPsychology (VITAL-NP)
The overarching goal of this study is to a) assess the feasibility and preliminary validity of home-based delivery of TeleNP to patients with suspected Alzheimer's Disease (AD), referred for cognitive assessments in a Neurology…
- Trial name
- VITAL-NP (NCT05379023)
- Testing
- Face-to-face evaluation (FF), TeleNP evaluation
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- University of Colorado, Denver
Acute Lymphoblastic Leukemia
Telematic Cognitive Training and Mindfulness in Pediatric Patients After CAR-T Cell Therapy, Single Hematopoietic Allogeneic Transplant or Chemotherapy
This randomized controlled clinical trial evaluates neurocognitive, biopsychological, and brain connectome outcomes in children and adolescents with acute lymphoblastic leukemia who have previously received Chimeric Antigen…
- Trial name
- PsyCARTkids (NCT07479927)
- Testing
- Digital cognitive training, Online Mindfulness-Based Intervention
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Universitario La Paz
Bipolar Disorder
The Bipolar Illness Onset Study (the BIO Study)
This longitudinal study aims to identify 1) a composite blood-based biomarker, 2) a composite electronic Smartphone-based biomarker and 3) a neurocognitive signature for bipolar disorder
- Trial name
- BIO (NCT02888262)
- Where
- Denmark
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Huntington Disease
Study of Biomarkers That Predict the Evolution of Huntington's Disease
Huntington's disease (HD) is a rare, autosomal dominant, progressive neurodegenerative disorder typically becoming noticeable in middle age.
- Trial name
- BIOHD (NCT01412125)
- Testing
- Huntington patient evaluation, Healthy subject evaluation
- Where
- France
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alzheimer's Disease, Frontotemporal Degeneration (Semantic & Behavioral Variants)
Social & Affective Cognition in Alzheimer's Disease & Associated Disorders
Recent studies have shown that individual neuropsychological scores of patients with Alzheimer's disease and Associated Disorders (ADAD) are only poorly correlated to their behavioral difficulties, such as disinhibition, apathy…
- Trial name
- SOCIALIZE (NCT06338397)
- Testing
- SCANN
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Treatment, Placebo
The Cognitive Enhancing Effects of D-Cycloserine Among Non-Demented Elderly
The goal of this study is to determine whether a study medication (d-cycloserine) improves the ability of older adults to perform on tests of neuropsychological functioning.
- Trial name
- NCT01361633
- Testing
- d-cycloserine, Sugar Pill
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Epilepsies, Partial, Epilepsy Intractable
Contribution of Genetics, Non-invasive Methods and Neuropsychology in Focal Cryptogenic Epilepsies
Patients with cryptogenic focal epilepsy (unknown cause) represent about the 30% of the entire population of epilepsy patients. Among them, about 30% are drug-resistant.
- Trial name
- NCT05015868
- Testing
- Standard of care, Functional magnetic resonance imaging-Electroencephalogram combined analysis, High density- electroencephalogram or 7 Tesla magnetic resonance imaging
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- IRCCS Eugenio Medea
Multiple Sclerosis
Technology-assisted Conscientiousness Therapy for People With Multiple Sclerosis
This is a validation study of a conscientiousness-based phone app intervention strategy to help people with their health management and employment.
- Trial name
- TACT-MS (NCT04953689)
- Testing
- Conscientiousness Coach
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Aortic Valve Stenosis, Postoperative Cognitive Dysfunction (POCD)
Prospective Neuropsychological Evaluation of the Implementation of a Heart Valve Unit (HVU-NEURO)
Transcatheter aortic valve implantation (TAVI) is an established treatment for severe aortic stenosis. Despite improved procedural outcomes, neurocognitive complications such as postoperative delirium (POD) and postoperative…
- Conditions
- Aortic Valve Stenosis, Postoperative Cognitive Dysfunction (POCD), Delirium - Postoperative, Neurocognitive Disorders
- Trial name
- HVU-NEURO (NCT07626567)
- Volunteers
- 500 people
- Sponsor
- Heart and Brain Research Group, Germany
Severe Traumatic Brain Injury
Approaches and Decisions for Acute Pediatric TBI Trial
Approaches and Decisions in Acute Pediatric TBI Trial (ADAPT) is an international research study designed to evaluate the impact of interventions on the outcomes of children with severe traumatic brain injury.
- Trial name
- ADAPT (NCT04077411)
- Testing
- Observational
- Where
- 48 sites in United States, Australia and 6 more
- Volunteers
- 1,000 people
- Sponsor
- University of Pittsburgh
Attention Deficit Hyperactivity Disorder, Behavior Hyperactive
Attention Deficit Hyperactivity Disorder
The ADA cohort aims for the systematic and standardized collection of sociodemographic, clinical and neuropsychological data, during 2 visits (inclusion and 12 months), from patients suffering from the co-occurrence of ADHD…
- Conditions
- Attention Deficit Hyperactivity Disorder, Behavior Hyperactive, Behavior Disorders
- Trial name
- ADA (NCT06232226)
- Testing
- Patients suffering from the co-occurrence of ADHD and addiction(s)
- Where
- 3 sites in France
- Volunteers
- 80 people
- Sponsor
- Nantes University Hospital