Clinical trials: Neurosciences
Parkinson Disease
Motor Training in PD
The purpose of this research study is to learn more about brain activity when individuals with and without Parkinson disease (PD) move their lower limbs.
- Trial name
- NCT02457832
- Testing
- Adapted Tango Dancing, Behavioral Control (BC) Condition
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Affect, Bereavement
Neural Mechanisms of Enhancing Emotion Regulation in Bereaved Spouses
This study investigates the underlying mechanisms of a novel emotion regulation intervention among recently bereaved spouses. More specifically, this study examines how thinking about an emotional stimulus in a more adaptive way…
- Conditions
- Affect, Bereavement, Emotions, Depressive Symptoms
- Trial name
- NCT04822194
- Testing
- Cognitive Emotion Regulation Training
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bryan Denny
Brain Injuries
Cortical Contributions to Motor Sequence Learning
The long-term objective initiated with this study is to determine which brain areas functionally contribute to learning a motor skill.
- Trial name
- NCT04138953
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- 2 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Emory University
Autism, Autism Spectrum Disorder
Autism Oxytocin Brain Project
The main goal of the study is to look at the effects of intranasal oxytocin on the brain in Autism Spectrum Disorder (ASD). Oxytocin is a hormone that exists naturally in the body and the brain, affecting a wide range of social…
- Trial name
- NCT03033784
- Testing
- 8 International Units (IU) of Oxytocin, 24IU of Oxytocin, 48IU of Oxytocin
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Emory University
Nicotine Use Disorder
Behavioral Memory Modulation in Nicotine Addiction
The purpose of the study is to see if a behavioral intervention known as retrieval-extinction training (RET) might affect craving in response to nicotine cues (e.g., pictures, videos and objects) and smoking behavior in men and…
- Trial name
- NCT03744559
- Testing
- Retrieval Extinction Training (RET), Control Retrieval Extinction Training (RET)
- Where
- United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alcohol Use Disorder, Alcohol Dependence
Altering Memories That Increase Risk of Relapse in Alcohol Use Disorders
The purpose of this study is to examine the effects of rapamycin (sirolimus) versus a placebo, an inactive substance, on responses to alcohol cues in individuals with alcohol use disorder.
- Trial name
- NCT03732248
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Vision Disorders
Bridging Animal and Human Models of Exercise-induced Visual Rehabilitation
This study will determine whether blood biomarker changes predict sight-saving benefits of exercise.
- Trial name
- NCT02911805
- Testing
- Aerobic exercise, Balance exercise
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Alcohol Drinking, Control
Neuroscience-Informed Treatment Development for Adolescent Alcohol Use
This study will examine the effect of N-Acetylcysteine (NAC), an over-the-counter antioxidant supplement, on brains of youth (ages 15-19) using magnetic resonance imaging (MRI).
- Trial name
- NCT03238300
- Testing
- N-Acetylcysteine
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Pain, Education
Virtual Reality Pain Neuroscience Education for Middle School Students
Investigating the use of a Virtual Reality (VR) pain neuroscience education (PNE) platform with middle school students. The investigators have previously studied the use of PNE with in person educational sessions with middle…
- Conditions
- Pain, Education, Virtual Reality
- Trial name
- NCT04470375
- Testing
- Virtual Reality Pain Neuroscience Education
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of South Dakota
Aging, Cognitive Ability, General
Lifestyle Enriching Activities for Research in Neuroscience Intervention Trial: LEARNit Study
The purpose of this study is to examine the effects of modifiable lifestyle factors including exercise and healthy living on brain health. The investigators will compare 2 types of interventions, moderate aerobic walking vs.
- Trial name
- NCT02726906
- Testing
- Moderate-aerobic walking, Positron Emission Tomography (PET) scan, Healthy living education
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Southern California