Clinical trials: Nevi
Segmental Dysplastic Nevi
Genetic Identification (ID) of Segmental Dysplastic Nevi
The investigators' goal is to identify the mutation in the gene that is responsible for the development of segmental dysplastic nevi. To identify the gene the investigators may use a candidate gene approach (i.e.
- Trial name
- NCT00955578
- Testing
- Punch Biopsy
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Epidermal Nevi, Nevus Sebaceus
12-week Study of NFX-179 Gel in Subjects With Epidermal Nevi
This study of NFX-179 is an open-label study, evaluating safety, tolerability, pharmacodynamic activity, and the clinical effect in subjects with Epidermal Nevus(ENS). NFX-179 is formulated as a gel for topical administration.
- Trial name
- NCT05195762
- Testing
- NFX-179 Gel 1.50%
- Where
- United States
- Sponsor
- Albert Chiou
Eyelid Tumor, Xanthelasma Palpebrarum
Efficacy and Safety of Ultrapulse Carbon Dioxide Laser Treatment in Eyelid Tumors
This study aims to assess the long-term efficacy and safety of ultrapulse carbon dioxide (CO₂) laser excision in the treatment of eyelid tumors, including xanthelasma, pigmented nevi, keratoses, and so on.
- Conditions
- Eyelid Tumor, Xanthelasma Palpebrarum, Pigmented Nevi, Keratosis
- Trial name
- NCT06206681
- Testing
- Ultra-pulsed Carbon Dioxide Laser
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Sun Yat-sen University
Nevi, Dysplastic
INTER-PATHOLOGIST READER STUDY
This is a post study histology analysis from previously obtained pathology slides.
- Trial name
- NCT06246903
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Orlucent, Inc
Melanoma, Melanoma in Situ
BioMEL- Diagnostic and Prognostic Factors in Melanoma.
The investigators' hypothesis is that cutaneous melanoma, melanoma in situ, dysplastic nevi and benign nevi all differ in not only clinical characteristics but also molecular and genotypic characteristics.
- Conditions
- Melanoma, Melanoma in Situ, Dysplastic Nevi, Mole (Dermatology)
- Trial name
- BioMEL (NCT05446155)
- Testing
- Imaging
- Where
- 4 sites in Sweden
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Nevi and Melanomas
Assessing Gene-Environment Interactions in Clinical Presentation of Nevi and Melanoma
This research study is designed to better understand the role of genetics, sun-exposure and phenotypic factors in melanoma.
- Trial name
- NCT03783325
- Testing
- UV Counseling, UV Photo, Biological Sample
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Malignant Melanoma, Merkel Cell Carcinoma
Optical Biopsy of Human Skin in Conjunction With Laser Treatment
This study is to compare the ability of optical biopsy. Research can use light enters the skin, collected, analyzed by the computer, and a picture created for the pathologist to conventional histologic examination compare with…
- Conditions
- Malignant Melanoma, Merkel Cell Carcinoma, Basal Cell Carcinoma, Squamous Cell Carcinoma
- Trial name
- NCT00540566
- Testing
- Optical Biopsy imaging
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Melanoma, Melanoma (Skin)
Atypical MOLes and Melanoma Early Detection Study (MoleMed)
This is a multicenter, ambispective, low-interventional clinical study evaluating molecular genetic markers for non-invasive differential diagnosis of benign and malignant pigmented skin and mucosal neoplasms.
- Conditions
- Melanoma, Melanoma (Skin), Moles, Nevus
- Trial name
- MoleMed (NCT04353050)
- Testing
- Non-invasive adhesive system (patch)
- Where
- 2 sites in Russia
- Volunteers
- 350 people
- Sponsor
- Russian Academy of Medical Sciences
Melanocytic Nevi (MN)
Pregnancy-related Changes in Melanocytic Nevi
This study is to analyze whether more changes in melanocytic nevi (MN) occur in women during and after pregnancy compared to non-pregnant women of the same age and to analyze psychological effects of total body mapping and…
- Trial name
- NCT05148455
- Testing
- standard-of-care clinical skin examination, skin assessment with the 2D FotoFinder ATBM master system, data collection by participant questionnaire
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Choroidal Nevi, Uveal Melanoma
BAP1 Testing in Instance Choroidal Nevi or Uveal Melanoma
The BAP1 trial will examine the blood of patients diagnosed with choroidal nevi or uveal melanoma for a germline BAP1 mutation and other genetic markers associated with developing malignancy as well as additional sequencing of…
- Trial name
- NCT01925599
- Where
- 3 sites in United States
- Volunteers
- 133 people
- Sponsor
- Amy C Schefler, MD
Melanoma, Dysplastic Nevi
Family Study of Melanoma in Italy
During the course of a case-control study of melanoma conducted at the Bufalini Hospital, Cesena, Italy in the years 1994-1996, 20 families with 2 or 3 melanoma cases were identified and studied.
- Conditions
- Melanoma, Dysplastic Nevi, Melanocytic Nevi
- Trial name
- NCT00339222
- Where
- 7 sites in Italy, Spain
- Volunteers
- 1,708 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Congenital Melanocytar Nevi in the Lower Limb
Congenital Naevi of Lower Limb in the Child
Depending on its dimensions, it is difficult to predict if a congenital nevi of the lower limb can be surgically removed by a unique simple procedure or by a complex procedure (expander, skin graft etc..), with a good result.
- Trial name
- NAEVUS (NCT04297579)
- Where
- France
- Volunteers
- 176 people
- Sponsor
- University Hospital, Montpellier
Dysplastic Nevi
Prospective Study of 2 mm Margins for the Biopsy of Dysplastic Nevi
Non-interventional study to evaluate the utility of removing Dysplastic Nevi with a defined 2 mm margin.
- Trial name
- NCT03094273
- Testing
- Saucerization biopsy
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- NYU Langone Health
Acne, Actinic Keratosis
Potential Research Study Participant Registry
The purpose of the potential research study participant registry is to keep potential research subjects informed about any future research studies in which they may meet the criteria for enrollment.
- Conditions
- Acne, Actinic Keratosis, Dysplastic Nevi, Eczema
- Trial name
- NCT00710489
- Where
- United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Melanoma, Pigmented Skin Lesion
Artificial Intelligence-assisted Evaluation of Pigmented Skin Lesions
Malignant melanoma (MM) is a deadly cancer, claiming globally about 160000 new cases per year and 48000 deaths at a 1:28 lifetime incidence (2016).
- Conditions
- Melanoma, Pigmented Skin Lesion, Dysplastic Nevi
- Trial name
- NNCD (NCT03362138)
- Testing
- dermoscopy
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Assuta Hospital Systems
Malignant Melanoma, Pigmented Nevi
Early Diagnosis of Malignant Transformation of Pigmentary Skin Lesions
Malignant Melanoma is a deadly skin cancer that can be cured if diagnosed early. To date atypical pigmented skin lesions are diagnosed by appearance alone and many moles and lesions are excised unnecessarily and on the other hand…
- Conditions
- Malignant Melanoma, Pigmented Nevi, Skin Neoplasm
- Trial name
- NCT01167998
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Melanoma, Nevi
Training Primary Care Physicians to Perform Melanoma Opportunistic Surveillance
This is a four-phase educational intervention for primary care practitioners (PCPs) to perform opportunistic melanoma surveillance.
- Conditions
- Melanoma, Nevi, Skin Moles
- Trial name
- NCT02385253
- Testing
- Educational training program
- Where
- 2 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Atypical Nevi, Melanoma
Pilot Study Evaluating Sulforaphane in Atypical Nevi-Precursor Lesions
This is a pilot study to see if oral administration of freeze dried, powdered broccoli sprouts have any effect on whether moles end up becoming melanoma.
- Trial name
- NCT01568996
- Testing
- broccoli sprout extract - sulforaphane (BSE-SFN)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- John Kirkwood
Melanocytic Nevi, Acquired Melanocytic Nevi
Natural History Study of Moles and Suspicious Melanoma
Background: Melanocytic nevi, or "moles," are non-cancerous growths of a type of skin cell called a melanocyte. Large congenital melanocytic nevi (LCMN) are a special type of mole that begins to grow before birth and is larger…
- Conditions
- Melanocytic Nevi, Acquired Melanocytic Nevi, Primary Cutaneous Melanoma
- Trial name
- NCT00288938
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Cancer Institute (NCI)
Non-Small Cell Lung Carcinoma, Breast Cancer
A Study of V934/V935 Vaccine in Cancer Participants With Selected Solid Tumors (V934-002)
This is a two-part study to test the safety, tolerability, and immune response for V934/V935 vaccine using a new prime-boost regimen in participants with selected solid tumors.
- Conditions
- Non-Small Cell Lung Carcinoma, Breast Cancer, Melanoma, Upper GI Tract Carcinoma
- Trial name
- NCT00753415
- Testing
- V935, V934-EP
- Volunteers
- 37 people
- Sponsor
- Merck Sharp & Dohme LLC