Clinical trials: Nevirapine
HIV Infections
Three Month Course of Anti-HIV Medications for People Recently Infected With HIV
Short-term therapy may reduce the amount of HIV in the blood of adults recently infected with HIV. The purpose of this study is to see whether it is better for people to take a short course of anti-HIV drugs when they are first…
- Trial name
- NCT00087464
- Testing
- Emtricitabine, Nevirapine, Tenofovir disoproxil fumarate
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Long-term Study in Patients Under Anti-retroviral Combination Therapy Switching to Viramune®
Collecting data on maintaining anti-retroviral activity (quantitative HIV RNA determination) and immunological activity (CD4 cells) after switching from protease inhibitor or NNRTI to Nevirapine (Viramune®) and collecting of…
- Trial name
- NCT02191293
- Testing
- Viramune® tablets
- Volunteers
- 228 people
- Sponsor
- Boehringer Ingelheim
Tuberculosis, HIV
Rifampin and Nevirapine Interactions in Young Children
Nevirapine is the preferred nonnucleoside reverse transcriptase inhibitor (NNRTI) for treatment of HIV in children younger than 3 years old who have tuberculosis (TB) coinfection.
- Trial name
- NCT01699633
- Where
- Ghana
- Volunteers
- 58 people
- Sponsor
- The Miriam Hospital
HIV Infections
A Comparative Study of Combination Antiretroviral Therapy in Children and Adolescents With Advanced HIV Disease
To compare the antiviral activity, safety, toxicity, and steady-state pharmacokinetics of zidovudine, didanosine, and nevirapine used in combination in patients with HIV infection.
- Trial name
- NCT00000814
- Testing
- Nevirapine, Zidovudine, Didanosine
- Where
- 68 sites in United States, Puerto Rico
- Volunteers
- 390 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
One Month Dual Antiretroviral Prophylaxis to Prevent Resistance Mutations in Mothers Exposed to Single Dose Nevirapine
The purpose of this study is to determine whether providing zidovudine (ZDV) and didanosine (ddI) during labor and for one month postpartum can reduce the selection of nevirapine (NVP) resistance mutations postpartum in women who…
- Trial name
- NCT00142337
- Testing
- Zidovudine (ZDV), Didanosine (ddI)
- Where
- 32 sites in Thailand
- Volunteers
- 244 people
- Sponsor
- Institut de Recherche pour le Developpement
HIV Infections, Metabolism, Lipids
An Open-label, Non-randomized, Single-arm Study to Investigate the Mechanism(s) by Which Nevirapine Increases Plasma HDL in HIV+ Subjects
1. In order to obtain further insight as to how NVP affects HDL metabolism, the in vivo kinetics of the HDL apolipoprotein, Apo A-1, before and 6 weeks after initiation of NVP containing treatment were evaluated.
- Trial name
- NCT00144261
- Testing
- nevirapine
- Where
- 3 sites in Netherlands, United Kingdom
- Volunteers
- 15 people
- Sponsor
- Boehringer Ingelheim
HIV Infections
Study to Evaluate the Replacement of Reverse Transcriptase Nucleoside/Nucleotide Inhibitors by Nevirapine in Patients on Triple Treatment With Analogues Only
The purpose of this study is to evaluate the proportion of patients with viral load of HIV-1 < 50 copies after 48 weeks of follow-up after randomization to change or not to nevirapine.
- Trial name
- NCT00415090
- Testing
- Nevirapine
- Where
- 17 sites in Spain
- Volunteers
- 28 people
- Sponsor
- Hospital de Calella
HIV, Pregnancy
A Study to Evaluate the Effects of Genetic Factors on the Pharmacokinetics of Antiretroviral Drugs During Pregnancy and Lactation
Mother-to-child transmission of HIV (MTCT) during pregnancy and breastfeeding is prevented with maternal antiretroviral drugs (ARV) and infant nevirapine post-exposure prophylaxis (PEP).
- Conditions
- HIV, Pregnancy, Breastfeeding
- Trial name
- NCT02269462
- Testing
- Efavirenz, Nevirapine
- Where
- 3 sites in Nigeria
- Volunteers
- 460 people
- Sponsor
- Adeniyi Olagunju
HIV Infections
Evaluation of Renal Function, Efficacy, and Safety When Switching From Tenofovir/Emtricitabine Plus a Protease Inhibitor/Ritonavir, to a Combination of Raltegravir (MK-0518) Plus Nevirapine Plus Lamivudine in HIV-1 Participants With Suppressed Viremia and Impaired Renal Function (MK-0518-284)
To evaluate changes in renal function, efficacy, and safety when switching from a combination of tenofovir/emtricitabine (TDF/FTC) plus a protease inhibitor/ritonavir (PI/r) to a combination of raltegravir (MK-0518) plus…
- Trial name
- RANIA (NCT02116660)
- Testing
- Raltegravir (MK-0518), Nevirapine, Lamivudine
- Volunteers
- 11 people
- Sponsor
- Merck Sharp & Dohme LLC
HIV-1
Multiple Dose BE Study With Nevirapine 400mg PR Tablets
The objective of this steady state pivotal study is to compare the rate and extent of absorption and to evaluate Bioequivalence of test drug compared to the approved reference product in HIV infected individuals
- Trial name
- NCT02202005
- Testing
- Nevirapine, Viramune®
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- Ratiopharm GmbH
HIV Infections, Lipodystrophy
Changing to Nonprotease Inhibitor Treatment to Improve Side Effects
The purpose of this study is to learn whether changing from a type of anti-HIV drug called a protease inhibitor (PI) to another type of anti-HIV drug will help to lower the amount of fats or sugars in the blood.
- Trial name
- NCT00021463
- Testing
- Abacavir sulfate, Lamivudine and Zidovudine, Abacavir sulfate, Efavirenz
- Where
- 11 sites in United States
- Volunteers
- 342 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Antibiotics to Reduce Chorioamnionitis-Related Perinatal HIV Transmission
The purpose of this study is to see if antibiotic drugs given to treat an infection of the uterus during pregnancy can reduce the chances of HIV being passed from an HIV-positive mother to her baby.
- Trial name
- NCT00021671
- Testing
- Erythromycin, Nevirapine, Ampicillin sodium
- Where
- United States
- Volunteers
- 3,720 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
The Safety and Effectiveness of Nevirapine Plus Nelfinavir in HIV-1 Infected Patients Who Have Taken Stavudine
To determine the potential effects of 28 days of nevirapine treatment on the steady-state pharmacokinetics of nelfinavir and of stavudine (d4T), and to further evaluate the pharmacokinetics of nevirapine in combination with…
- Trial name
- NCT00002381
- Testing
- Nelfinavir mesylate, Nevirapine, Stavudine
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Boehringer Ingelheim
HIV Infections, Pregnancy
Nevirapine Plus Zidovudine to Prevent Perinatal HIV in Thailand
The purpose of this study was to assess the efficacy of a single dose of the drug nevirapine (NVP) given to pregnant women at onset of labor and to their infant 48-72 hours after birth in addition to standard oral zidovudine (ZDV…
- Trial name
- NCT00398684
- Testing
- Single dose nevirapine to the mother and to the child
- Where
- Thailand
- Volunteers
- 1,792 people
- Sponsor
- Institut de Recherche pour le Developpement
HIV, Pregnancy
Maternal TDF and FTC to Reduce NNRTI Resistance Mutations After Intrapartum NVP
The purpose of this study is to determine whether the addition of tenofovir (TDF) and emtricitabine (FTC)to a standard PMTCT regimen containing single-dose nevirapine (NVP) can reduce the development of post-ingestion HIV…
- Trial name
- TD-2 (NCT00204308)
- Testing
- Combination tenofovir-emtricitabine
- Where
- 2 sites in Zambia
- Volunteers
- 400 people
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infections
ATV/Ritonavir Nevirapine Interaction (USPAC)
Open-Label, multiple-dose, drug interaction study to assess the effect of nevirapine on the pharmacokinetics of atazanavir in HIV-infected individuals.
- Trial name
- NCT00162149
- Testing
- Nevirapine, Nevirapine + Atazanavir/Ritonavir, Atazanavir + Ritonavir
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 46 people
- Sponsor
- Bristol-Myers Squibb
HIV
Moringa Oleifera- Antiretroviral Pharmacokinetic Drug Interaction
A study will be conducted by scientists from the University of Zimbabwe to determine if antiretroviral drugs are affected by taking herbs at the same time.
- Trial name
- NCT01410058
- Testing
- Moringa oleifera, Efavirenz 600mg, Nevirapine 200Mg Oral Tablet
- Where
- Zimbabwe
- Volunteers
- 19 people
- Sponsor
- University of Zimbabwe
Tuberculosis, Aids
Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patients (ANRS 12146 CARINEMO)
The purpose of this study is to determine whether the use of Nevirapine in HIV patients already treated against tuberculosis by Rifampicin is as efficient and as well tolerated as Efavirenz.
- Conditions
- Tuberculosis, Aids, Hiv Infections
- Trial name
- CARINEMO (NCT00495326)
- Testing
- Nevirapine based therapy, Efavirenz based therapy, Rifampicin (RMP) Ethambutol (E) Isoniazid (H) Pyrazinamid (Z)
- Where
- 3 sites in Mozambique
- Volunteers
- 570 people
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
HIV Infections
Impact of Switching to NNRTI-based Therapy on the Quality of Life of HIV-infected Patients With Virological Suppression
Observational study to evaluate therapeutic switch to a NNRTI-based regimen on quality of life of HIV-positive patients
- Trial name
- NCT02191202
- Testing
- Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTI)
- Volunteers
- 283 people
- Sponsor
- Boehringer Ingelheim
HIV Infections
A Study to Compare Two Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Previously Received Anti-HIV Treatment
The purpose of this study is to compare the safety and effectiveness of 2 anti-HIV drug combinations in HIV-infected patients. Both combinations will include nevirapine (NVP), 2 nucleoside reverse transcriptase inhibitors…
- Trial name
- NCT00004581
- Testing
- Lopinavir/Ritonavir, Nevirapine
- Where
- 88 sites in United States, Australia and 12 more
- Volunteers
- 300 people
- Sponsor
- Abbott