Clinical trials: New Technologies
Hearing Loss
Evaluation of New Fitting Characteristics for Extended Wear Hearing Aid Technology
Two groups of hearing aid candidates will be fit with extended wear technology. One group will be fit with the commercially available models, and the other group will be fit with either the commercially available model or a new…
- Trial name
- NCT05274165
- Testing
- Lyric Hearing Aid- Experimental Design, Lyric Hearing Aid- Commercially Available
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sonova AG
Osteoporosis, Postmenopausal, Osteoporosis Fracture
New Biomarkers and Therapeutic Targets in Osteoporosis Via Omics Technologies
This study aims to discover novel biomarkers and therapeutic targets for osteoporosis through the use of advanced omics technologies, including proteomics and metabolomics.
- Conditions
- Osteoporosis, Postmenopausal, Osteoporosis Fracture, Osteoporosis, Severe
- Trial name
- NCT06525688
- Testing
- Bone, Serum and Plasma sample
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- National and Kapodistrian University of Athens
Pain
A New Treatment for Chronic Pain Combining Neuromodulation, Computer Assisted Training and Telemonitoring
Chronic pain (CP) is a leading cause of medical disability, healthcare expenditure, and reduced psychological well-being. Given the limited mobility, travel burden, and cost, access to care can be problematic for patients…
- Trial name
- TechNoPain (NCT06306053)
- Testing
- tDCS+EuleriaLab, tDCS, EuleriaLab
- Where
- 3 sites in Italy
- Volunteers
- 126 people
- Sponsor
- ASST Santi Paolo e Carlo
Motor Neuron Disease
Technical Evaluation of Earswitch Phase B
The Earswitch is a demonstrated proof-of-concept that detects the voluntary contraction of a small muscle in the ear, called the tensor tympani (TT) muscle, which can be effectively used as an input switch.
- Trial name
- NCT06090448
- Testing
- EarSwitch device
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Bath
Peripheral Artery Disease (PAD)
Use of Three-Dimensional Printed Models for Endovascular Planning and Follow-up in Patients Affected by Aorto-Iliac-Femoral-Popliteal Arterial Disease Undergoing Balloon Angioplasty. A Single-center, Single-blind Randomized Controlled Trial
Lower extremity peripheral arterial disease is a major health problem. Currently, balloon angioplasty represents the most commonly performed treatment for patients affected by vascular claudication or critical limb ischemia.
- Trial name
- 3DPAD-1 (NCT07000097)
- Testing
- PTA planning supported by 3D-printed model, PTA (Standard of Care)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Violence
A Multi-Center Randomized Controlled Trial of Mentoring to Prevent Youth Violence
The purpose of this study is to test whether a violence prevention curriculum delivered by Big Brothers and Big Sisters staff and mentors can reduce violence involvement for assault-injured youth.
- Trial name
- TC2 (NCT01770873)
- Testing
- Take Charge 2
- Where
- 2 sites in United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Small Breast Lesions, Dense Breast Tissue
Molecular Breast Imaging: A Novel Technology for Detection of Malignant Breast Lesions
Detection of breast cancer as early as possible is an ongoing imaging challenge.The purpose of the current study is to assess the clinical performance of the new scintigraphic technology, a dedicated breast gamma camera composed…
- Conditions
- Small Breast Lesions, Dense Breast Tissue, Discrepancy With Clinical Examination, Equivocal Mammographic, Sonographic or MRI Lesion
- Trial name
- NCT01004666
- Where
- Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Stroke, Hemiplegia
New Technologies in the Rehabilitation of Chronic Stroke
The objective of the current study is to develop and investigate training concepts involving rehabilitation technology, which aim at exploiting the potential for regaining the ability to perform skilled movements by maximizing…
- Trial name
- SRTI (NCT03641651)
- Testing
- Rehabilitation technology
- Where
- 4 sites in Switzerland
- Volunteers
- 15 people
- Sponsor
- Markus Wirz
Peripheral Arterial Disease, Personal Satisfaction
CONTECI Program: A New Way to Control Peripheral Arterial Disease Using New Technologies
The current increase in chronic diseases calls for changes to the health system. It is necessary to promote expert patient in chronic disease.
- Conditions
- Peripheral Arterial Disease, Personal Satisfaction, Telemedicine
- Trial name
- NCT02762916
- Testing
- Selfmanage with the help of telemedicine program
- Volunteers
- 150 people
- Sponsor
- Consorci Sanitari del Maresme
Minimal Residual Disease, Pancreatic Cancer Resectable
Evaluate the Clinical Feasibility of a Novel Neoantigen-Reactive CD8+ T Cell (NART) Detection Technology for Postoperative MRD Surveillance of Pancreatic Cancer
The goal of this observational study is to learn about the diagnostic performance of a novel Neoantigen-Reactive CD8+ T cell (NART) technology detecting minimal residual disease (MRD) in postoperative surveillance of pancreatic…
- Trial name
- NCT06941987
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Shanghai Zhongshan Hospital
Obesity
Mobile Health Intervention
The purpose of this study is to evaluate the efficacy of a distance follow-up on body mass index decrease at 15 months compared to traditional management in obese adolescents.
- Trial name
- MHI (NCT02955017)
- Testing
- traditional follow_up, distance follow-up "new technologies"
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Adolescent Behavior, Physical Activity
Adolescents' Health Through Mobile Apps, Wearables, and a Gamified TAC ( ActivA-App )
A primary factor in preventing diseases in adulthood, as well as overweight and obesity, is the promotion of physical activity from childhood and adolescence.
- Conditions
- Adolescent Behavior, Physical Activity, New Technologies
- Trial name
- ActivA-App (NCT06140225)
- Testing
- "PACER" Application, "MapMyWalk" Application, "Strava" Application
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Aging, Healthy
Biological Age in Health Promotion - Novel Health Technology
The purpose of this cross-sectional study is to collect relevant molecular markers of aging and measures of physiological function.
- Trial name
- BATE (NCT03680768)
- Testing
- Health Assessment
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Patient Safety, Organizational Change
Generalizing TESTPILOT to New Single Family Room NICUs
Complex service interventions are neither smooth nor easy in any transitioning healthcare facility. Simulations performed in the new environment reinforce patient safety by uncovering safety threats, enabling their correction…
- Trial name
- TESTPILOT (NCT02574104)
- Testing
- Simulate a functional NICU prior to moving patients
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
New Educational Technologies
Web Tutorial Based on Case Vignettes for Teaching Literature Critical Assessment to Nursing Students
Objective: The aim of this study is to assess the efficacy of a web tutorial based on case vignettes as a complementary tool for teaching literature critical assessment to nursing students, in terms of: 1) knowledge, 2) tutorial…
- Trial name
- NCT01804868
- Testing
- case vignette tutorial, passive web presentation on research regulation
- Where
- France
- Volunteers
- 506 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Nasopharyngeal Neoplasms
A New EBV Related Technologies of T Cells in Treating Malignant Tumors and Clinical Application
The purpose of this study is to evaluate the safety of the designed LMP1-CAR -T cells and determine whether the CAR-T cells are effective in the treatment of EBV associated malignant tumors.
- Trial name
- NCT02980315
- Testing
- CAR-T cells
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Lung Cancer
NovellusDx Functional Profiling of Oncogenic Mutations in Lung Cancer Patients
NovellusDx technology identifies tumor-specific driver mutations, but unlike sequencing-based tests, NovellusDx has a functional assay that detects dis-regulated translocation of mutated signaling proteins to the nucleus.
- Trial name
- NCT02274025
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Fore Biotherapeutics
Diabetes Mellitus in Pregnancy
SweetMama: Testing of a Novel Technology for Diabetes Education and Support to Pregnant Women
Diabetes during pregnancy is a challenging clinical situation requiring substantial patient engagement. The investigators have developed a novel early-phase tool, called SweetMama, that incorporates educational, motivational and…
- Trial name
- NCT03240874
- Testing
- SweetMama Focus Groups, SweetMama Individual Testing, SweetMama Feasibility Testing - Pilot Randomized Trial
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Catheter Ablation, Radiofrequency, Atrial Fibrillation
Impact of a New Ablation Tracking Tool in Paroxysmal Atrial Fibrillation Ablation With Contact Force Technology
Pulmonary vein isolation (PVI) is the cornerstone of atrial fibrillation (AF) ablation. A novel technology was recently developed to allow an automatic points annotation when indirect parameters of lesion formation reach…
- Trial name
- VISITALY (NCT02681926)
- Testing
- VISITAG
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Giulio Zucchelli
Dental Anxiety, Music Therapy
Use of Augmented Reality Glasses and Noise-Cancelling Headphones to Reduce Dental Anxiety in Adult Patients
This study investigates whether new audiovisual technologies can help reduce anxiety and stress experienced by adult patients during dental procedures. Dental fear and anxiety are common barriers to receiving proper oral care.
- Conditions
- Dental Anxiety, Music Therapy, Oral Surgical Procedures
- Trial name
- NCT07398898
- Testing
- AR Glasses with Video and Music, ANC Headphones with Music
- Where
- Poland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw