Clinical trials: Newborn Health
Reproductive, Maternal, Newborn, and Child Health, Integrated, Community-Health Systems
Implementing an Integrated RMNCH Intervention by Community Health Workers in Achham and Dolakha: National Pilot
The investigators will conduct a cluster-controlled, stepped wedge implementation science trial of a bundled reproductive, maternal, neonatal, and child healthcare (RMNCH) delivery intervention within an approximate population of…
- Trial name
- NCT03371186
- Testing
- Community Health Worker, Continuous Surveillance, CB-Integrated Management of Newborn and Childhood Illness
- Where
- 2 sites in Nepal
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Possible
Cardiovascular Risk Factor, Cardiovascular Diseases
Umbrella Review of the DASH Dietary Pattern and Cardiometabolic Risk
The European Association for the Study of Diabetes (EASD) guidelines have not made any specific recommendations regarding the Dietary Approaches to Stop Hypertension (DASH) diet, a dietary pattern that emphasizes fruits and…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Coronary Heart Disease, Stroke
- Trial name
- NCT03542370
- Testing
- DASH dietary pattern
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Retinopathy of Prematurity (ROP)
HBM-Based Education for Retinopathy of Prematurity Screening in Parents of Premature Infants
The goal of this clinical trial is to learn whether Health Belief Model (HBM)-based educational interventions can improve knowledge and practices related to Retinopathy of Prematurity (ROP) screening among parents of premature…
- Trial name
- NCT07661654
- Testing
- HBM-Based Video Education, HBM-Based Audio Education, Standard Counselling and Pamphlet
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Birth Asphyxia, Neonatal Death
Development of a Mobile Application for HBB Prompt Study
This study applies an iterative user-centred design approach involving frontline birth attendants to create a mobile application ("HBB Prompt") to improve skills retention after initial newborn stabilization training through the…
- Trial name
- HBB-Prompt (NCT03577054)
- Testing
- HBB Prompt, Low-Dose High Frequency training
- Where
- Uganda
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mbarara University of Science and Technology
Heart Defects, Congenital, Mental Health Issue
Mind the Heart - Mental Health in Children and Adolescents With Congenital Heart Defects
The aim of the Mind the Heart study is to document the feasibility of an online parent/child administered screening model for mental disorders (MDs) in Danish children and adolescents with congenital heart disease (CHD).
- Trial name
- Mind the Heart (NCT05709470)
- Testing
- No-intervention
- Where
- Denmark
- Volunteers
- 4,800 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Patient Empowerment
Actions for Empowered Maternal Neonatal Care (ACUNE): A Nursing Intervention
The quality of care premature infants receive at home after hospital discharge is critical to their health and well-being. Premature infants require special care, which is why Neonatal Intensive Care Units (NICUs) have processes…
- Trial name
- ACUNE (NCT05005988)
- Testing
- Actions for Empowered Maternal Neonatal Care
- Where
- Colombia
- Volunteers
- 30 people
- Sponsor
- Universidad de Antioquia
Congenital Heart Disease, Mother Child Interaction
Creative Music Therapy in Newborns With Congenital Heart Disease
In the context of a clinical trial, the investigators will evaluate if parent-infant interaction can be improved by a family integrated, individualised, interactive resource- and needs-oriented music therapy approach in the dyads…
- Trial name
- BOND (NCT05702203)
- Testing
- Creative Music Therapy
- Where
- Switzerland
- Volunteers
- 164 people
- Sponsor
- University Children's Hospital, Zurich
Hemophilia A
Long-term Study Evaluating Joint Health in People With Haemophilia A Receiving Real-world Prophylactic Treatment With Efanesoctocog Alfa
The rationale for this study is to further understand and describe the long-term prophylactic effectiveness of efanesoctocog alfa in preventing joint bleeds in a real-life setting.
- Trial name
- NCT06940830
- Testing
- Efanesoctocog alfa
- Where
- 31 sites in Croatia, Czechia and 6 more
- Volunteers
- 252 people
- Sponsor
- Swedish Orphan Biovitrum
Infant, Cerebral Palsy
Early Support and Physiotherapy for Children and Their Motor Skills
The App-eMot-Quali project proposed here is the first phase in the implementation of a care pathway supported by a digital tool.
- Conditions
- Infant, Cerebral Palsy, Neonatal
- Trial name
- App-eMot-Quali (NCT04523441)
- Testing
- Focus group, Semi-directive interview
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Familial Hypercholesterolemia
A Prospective Cohort Study on Familial Hypercholesterolemia in Health Examination Population
To determine the prevalence and the prognosis in a corhort of patients with familial hypercholesterolemia (FH).
- Trial name
- NCT04958629
- Testing
- familial hypercholesterolemia
- Volunteers
- 318 people
- Sponsor
- Peking University Third Hospital
Sleep, Cerebral Oxygenation
Respiratory Support and Brain Health in Preterm Infants
Premature babies often require breathing support during their neonatal intensive care unit stay. This is because their lungs are not fully developed to perform the work of breathing on their own.
- Trial name
- NCT05589831
- Testing
- Non-invasive Neurally Adjusted Ventilatory Assist
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Mount Sinai Hospital, Canada
Labor Pain
Intermittent Automated Devices for Labor Analgesia in Emilia Romagna
The study aims to determine whether the use of automated intermittent devices for labor analgesia could prevent the increase of instrumental deliveries, with same analgesia.
- Trial name
- PA-RER (NCT02710877)
- Testing
- Programmed Intermittent bolus, Manual epidural bolus, Levobupivacaine
- Where
- 3 sites in Italy
- Volunteers
- 671 people
- Sponsor
- University of Modena and Reggio Emilia
Down Syndrome
MOTOR PROFICIENCY AND HEALTH-RELATED FITNESS IN DOWN SYNDROME
People with Down syndrome (DS) seem to have a lower physical fitness than their peers without disabilities. Purpose: To examine the correlation of gross motor proficiency to health-related physical fitness ( HRPF) in children…
- Trial name
- NCT07702201
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Gout, Low Medication Adherence
SToRytelling to Improve DiseasE Outcomes in GOut: The STRIDE-GO2 Study
The objective is to test the efficacy of a patient-centered, culturally relevant narrative intervention, or "storytelling," based on the solid conceptual foundation of the narrative communication theory and the constructs of the…
- Conditions
- Gout, Low Medication Adherence, Health Related Quality of Life
- Trial name
- STRIDE-GO2 (NCT02741700)
- Testing
- Gout Storytelling Video Intervention
- Where
- 3 sites in United States
- Volunteers
- 306 people
- Sponsor
- VA Office of Research and Development
COVID-19
INTEGrating Ag-RDTs for COVID-19 in MNCH,HIV and TB Services in Cameroon and Kenya
Integration of antigen-detecting rapid diagnostic tests (Ag-RDT) for COVID-19 into services that provide care for vulnerable populations such as pregnant women, children, people with HIV infection, and patients with tuberculosis…
- Trial name
- INTEGRATE (NCT05382130)
- Testing
- Test all
- Where
- 2 sites in Cameroon, Kenya
- Volunteers
- 152,082 people, healthy volunteers welcome
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
Cerebral Palsy, Down Syndrome
Investigation of Parents' Anxiety Level and Health Related Quality of Life in Different Types of Physical Disabilities
Disability brings many psychosocial problems in society. The effects of the health of a disabled child on the psychological health and quality of life of the family are inevitable.
- Conditions
- Cerebral Palsy, Down Syndrome, Spina Bifida, Muscular Dystrophy
- Trial name
- NCT04035967
- Testing
- Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Sanko University
Monogenic Diseases, Genetic Diseases, Inborn
Health Economic Evaluation of Non-Invasive Prenatal Exclusion Diagnosis
Since the discovery of a small fraction of circulating cell-free fetal DNA (ccffDNA) in the blood of the mother, non-invasive prenatal diagnosis (NIPD) techniques using a simple blood sample have been developed to 1) screen for…
- Trial name
- PRENATSAFE (NCT07469657)
- Testing
- NIPD by NGS
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Health Knowledge, Attitudes, Practice, Sneezing
"Anticipatory Guidance in the Nursery and Its Impact on Non-urgent Emergency Department Visits"
Kennedy et al, in a study of pediatric Emergency Department (ED) use by newborns less than 14 days of age, revealed that half of all visits in this population were non-acute problems.
- Conditions
- Health Knowledge, Attitudes, Practice, Sneezing, Constipation, Nasal Congestion and Inflammations
- Trial name
- NCT01859065
- Testing
- Intensified anticipatory guidance, Routine
- Where
- United States
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Bronx-Lebanon Hospital Center Health Care System
Iodine Deficiency, Thyroid
Iodine Impact on Thyroid Function and Psychomotor Development, Observational Study in the Portuguese Minho Region
Full intellectual capabilities are achieved only if crucial nutrients are present during development. Iodine deficiency is the most common cause of preventable brain harm in infants.
- Conditions
- Iodine Deficiency, Thyroid, Pregnancy Related, Psychomotor Impairment
- Trial name
- IodineMinho (NCT04288531)
- Testing
- Iodine supplementation
- Where
- 10 sites in Portugal
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University of Minho
Cystic Fibrosis
A Coaching Intervention to Young Adults With Cystic Fibrosis
The treatment burden for patients with cystic fibrosis (CF) is significant and poor adherence has been well-documented. The investigators hypothesize that a coaching intervention will empower young adults with CF to manage their…
- Trial name
- NCT02110914
- Testing
- Coaching
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
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