Clinical trials: Newly Diagnosed Breast Cancer, active
Breast Cancer, Symptom, Behavioral
YES Study - Newly Diagnosed/Metastatic Intervention
This research study is being done to monitor common symptoms and behavior, and to provide supportive care information and peer support, as well as research opportunities for young women ages of 18-39 years old who have been…
- Trial name
- YES (NCT04379414)
- Testing
- YES portal
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer Female, Thyroid Gland
Evaluation of Thyroid Abnormity Incidence and Thyroid Toxicity During Chemotherapy Among Newly Diagnosed Breast Cancer
Breast cancer is one of the most common cancers in China. Even though advances in the field of breast cancer therapeutics, chemotherapy remains the mainstay therapeutic modality.
- Trial name
- NCT03177902
- Testing
- Chemotherapy
- Where
- China
- Volunteers
- 400 people
- Sponsor
- The First Affiliated Hospital of Bengbu Medical University
Malignant Neoplasm of Breast
An Early Stress-Reduction Intervention in Patients With Newly Diagnosed Breast Cancer
The goal of this research study is to learn if starting a stress-reduction program before treatment can affect your stress, mood, and physical symptoms during and after treatment for cancer. This is an investigational study.
- Trial name
- NCT03429907
- Testing
- Mind-Body Exercises, Questionnaires
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- M.D. Anderson Cancer Center
Glioblastoma, Melanoma Stage IV
A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors
This is an open-label, two-part, phase 1-2 dose-finding study designed to determine the safety, tolerability, PK, PD, and proof-of-concept efficacy of ST101 administered IV in patients with advanced solid tumors.
- Conditions
- Glioblastoma, Melanoma Stage IV, Breast Cancer, Prostate Cancer
- Trial name
- NCT04478279
- Testing
- ST101, Temozolomide, Radiation
- Where
- 11 sites in United States, United Kingdom
- Volunteers
- 125 people
- Sponsor
- Sapience Therapeutics
Breast Cancer, Recurrent Breast Cancer
A Study of Diffusing Alpha Radiation Therapy for Patients With Breast Carcinoma in Frail or Elderly Patients.
A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for the treatment of newly diagnosed or Recurrent Breast Carcinoma in frail or elderly patients.
- Conditions
- Breast Cancer, Recurrent Breast Cancer, Breast Carcinoma
- Trial name
- NCT06202118
- Testing
- Diffusing Alpha Radiation Emitters Therapy (DaRT)
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Alpha Tau Medical LTD.
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
A Physical Activity Program Compared to Health Education for Improving Memory and Attention in Hispanic Women With Newly-Diagnosed Stage I-IIIa Breast Cancer, MAMA Trial
This clinical trial compares a physical activity program to a health education program for improving memory and attention in Hispanic women who are 50 years of age or older and are newly-diagnosed with stage I-IIIa breast cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Cancer-related Cognitive Dysfunction
- Trial name
- NCT07331077
- Testing
- Accelerometry, Aerobic Exercise, Electronic Health Record Review
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Breast Cancer Detection
FAP PET/CT for Staging Patients With Breast Cancer
This study aims to evaluate the clinical utility of [68Ga]Ga-FAP-2268 PET/CT for disease staging and assessment in patients with high-risk primary breast cancer.
- Trial name
- NCT07523607
- Testing
- 68Ga-FAP-2286
- Volunteers
- 65 people
- Sponsor
- Odense University Hospital
Breast Cancer
Preoperative Immunotherapy Combined With Stereotactic Radiation Therapy Boost in the Treatment of HER2-negative Breast Cancer
The goal of the study is to assess the safety and effectiveness of the combination of anti-PD1 immunotherapy (pembrolizumab) and radiotherapy in the preoperative treatment of HER2-negative breast cancer resistant to classical…
- Trial name
- BREAST-BOOSTER (NCT06472583)
- Testing
- Keytruda, Preoperative radiation therapy
- Where
- Poland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Invasive Breast Carcinoma, Stage II Breast Cancer AJCC v6 and v7
Carboplatin and Paclitaxel With or Without Atezolizumab Before Surgery in Treating Patients With Newly Diagnosed, Stage II-III Triple-Negative Breast Cancer
This phase II trial studies how well carboplatin and paclitaxel with or without atezolizumab before surgery works in treating patients with newly diagnosed, stage II-III triple negative breast cancer.
- Conditions
- Invasive Breast Carcinoma, Stage II Breast Cancer AJCC v6 and v7, Stage III Breast Cancer AJCC v7, Triple-Negative Breast Carcinoma
- Trial name
- NCT02883062
- Testing
- Atezolizumab, Biospecimen Collection, Carboplatin
- Where
- 14 sites in United States
- Volunteers
- 67 people
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer
Neoadjuvant Lenvatinib Combined With Letrozole in Hormone Receptor Positive Breast Cancer
This is a single-centre study comprising two phases: a lead-in phase Ib and a phase II randomized portion. Lead-in Phase Ib study A lead-in phase I study will be built into this protocol to confirm the dose of lenvatinib that can…
- Trial name
- NCT02562118
- Testing
- Lenvatinib + Letrozole
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- National University Hospital, Singapore
Estrogen Receptor Positive Breast Cancer
A Study to See Whether Estrogen Can Slow the Growth of Some ER Positive Breast Cancers
Some breast cancers have estrogen receptors (ER+). The investigators know that some ER+ tumours can be cured by hormone therapy alone while other ER+ breast cancers cannot.
- Trial name
- PRESTO (NCT02238808)
- Testing
- Estradiol
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- AHS Cancer Control Alberta
Breast Cancer Females
The Effect of Group and Mobile Wellness Coaching Given to Women With Breast Cancer on the Disease
It is believed that this study will serve as a model for a Wellness Coaching program delivered to patients newly diagnosed with breast cancer via a mobile application and contribute to the literature.
- Trial name
- NCT07364760
- Testing
- Wellness coaching program with mobile application, Group Wellness Coaching Program, Mobile app and group wellness coaching program
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Breast Cancer, Decision Aid
Decision Aid for Women Newly Diagnosed With Breast Cancer
The goal of this multi-center randomized controlled trial is to determine if the clinical decision aid (BCT Aid) works to help breast cancer patients participate in decision-making and make high-quality decisions, thereby…
- Conditions
- Breast Cancer, Decision Aid, Shared Decision Making, Cost Effectiveness
- Trial name
- BCT Aid (NCT07497256)
- Testing
- BCT Aid, Usual Care
- Where
- 3 sites in China
- Volunteers
- 160 people
- Sponsor
- Xiamen University
Breast Cancer Stage IV
Phase II Study of Dato-DXd in Triple-negative Breast Cancer Patients With Newly Diagnosed or Progressing Brain Metastases
Datopotamab-deruxtecan in triple-negative breast cancer patients with newly diagnosed or progressing brain metastases.
- Trial name
- TUXEDO-2 (NCT05866432)
- Testing
- Datopotamab deruxtecan
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University of Vienna
Breast Cancer, Metastatic Breast Cancer
T-DXd Therapy for HER2-low Breast Cancer Patients With Brain Metastases
TUXEDO-4 is an international, multicentric, single arm, phase II study aiming to gather additional solid evidence of Trastuzumab-Deruxtecan (T-DXd) activity in patients with Human Epidermal Growth Factor Receptor 2 (HER2)-low…
- Trial name
- TUXEDO-4 (NCT06048718)
- Testing
- Trastuzumab-Deruxtecan (T-DXd)
- Where
- 13 sites in Austria, Spain
- Volunteers
- 28 people
- Sponsor
- MedSIR
Metastatic Breast Carcinoma, Stage IV Breast Cancer AJCC v6 and v7
Pembrolizumab, Endocrine Therapy, and Palbociclib in Treating Postmenopausal Patients With Newly Diagnosed Metastatic Stage IV Estrogen Receptor Positive Breast Cancer
This phase II trial studies how well pembrolizumab works when given together with endocrine therapy and palbociclib in treating postmenopausal patients with newly diagnosed stage IV estrogen receptor positive breast cancer that…
- Trial name
- NCT02778685
- Testing
- Fulvestrant, Laboratory Biomarker Analysis, Letrozole
- Where
- 7 sites in United States
- Volunteers
- 47 people
- Sponsor
- City of Hope Medical Center
Breast Cancer
Podcast-Based Psychosocial Support for Women Newly Diagnosed With Breast Cancer
This study will evaluate a podcast-based psychosocial support program for women who have been newly diagnosed with breast cancer.
- Trial name
- NCT07883109
- Testing
- Psychosocial Support Program
- Volunteers
- 80 people
- Sponsor
- Mei Man
Breast Cancer
Respiratory Muscle Strength Training to Prevent Respiratory Muscle Weakness in Adults Newly Diagnosed With Breast Cancer
The goal of this clinical trial is to learn if respiratory muscle strength training can prevent respiratory muscle weakness in adults who are newly diagnosed with breast cancer and are planning to have surgery.
- Trial name
- NCT07229378
- Testing
- Respiratory muscle strength training, Guided Imagery Exercises
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
Breast Cancer
A Novel Patient Decision Aid for Surgical Treatment Options in Early-Stage Breast Cancer
This is a study to assess the feasibility and acceptability of a novel decision aid (DA) in a newly diagnosed, early-stage breast cancer population.
- Trial name
- NCT06813053
- Testing
- Decision Aid (DA), Standard of Care (SOC)
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With Newly Diagnosed Breast Cancer
This trial studies the acceptability and how well decision making tool works in supporting decision making in contralateral prophylactic mastectomy in patients with newly diagnosed breast cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT02918474
- Testing
- Decision Aid, Questionnaire Administration
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- M.D. Anderson Cancer Center