Clinical trials: Nicotine Replacements Therapy
Qualitative, Nicotine Replacement Therapy
Experiences of Pregnant Women Who Use NRT in Pregnancy as Part of a Quit Attempt
This study is largely a qualitative study with a small survey component. The aim of the survey would be to gain a quantitative perspective of how women use NRT after this has been prescribed by stop smoking services (SSS).
- Conditions
- Qualitative, Nicotine Replacement Therapy, Pregnancy
- Trial name
- NCT02125370
- Testing
- Qualitative and survey
- Where
- 2 sites in United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Smoking Cessation
Nicotine Replacement Therapy (NRT) Sampling and Selection to Increase Medication Adherence
To determine the preliminary impact on Nicotine Replacement Therapy (NRT)adherence and examine the underlying mechanisms of action associated with adherence.
- Trial name
- NRT (NCT03276780)
- Testing
- Counseling, combination NRT
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Alabama at Birmingham
Smoking Cessation
Telephone Counseling and the Distribution of Nicotine Patches to Smokers
The primary purpose of this study is to determine the effects of distributing free nicotine replacement therapy (NRT) to tobacco quitline callers directly. Specifically, this study aims to: 1.
- Trial name
- NCT00851357
- Testing
- Nicotine Patch, Telephone Counseling, Self-Help Materials
- Where
- United States
- Volunteers
- 4,200 people
- Sponsor
- University of California, San Diego
Nicotine Dependence, Cigarettes, Nicotine Withdrawal
The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments
The INITIATE Study is a randomized controlled trial that is testing an intervention designed to increase long-term abstinence among tobacco smokers seen in emergency departments (ED) and other high-volume hospital and community…
- Trial name
- INITIATE (NCT04163081)
- Testing
- Quit Card Intervention (QCI)
- Where
- 4 sites in Canada
- Volunteers
- 1,208 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Smoking Cessation
Nicotine Replacement Therapy and Cardiovascular Disease
The aim of this study is to compare the cardiovascular disease event rate in smokers undertaking pharmacologically unaided smoking cessation attempts (the non-exposed group) with the event rate in smokers attempting smoking…
- Trial name
- NCT02195739
- Where
- United Kingdom
- Volunteers
- 61,050 people, healthy volunteers welcome
- Sponsor
- Research in Real-Life Ltd
Endothelial Dysfunction
Impact of Smoking Cessation and γ-Tocopherol to Restore Vascular Endothelial Function
Cigarette smoking is a significant risk factor for cardiovascular disease (CVD) and is the leading cause of premature mortality in the US.
- Trial name
- NCT01314443
- Testing
- Nicotine Replacement Therapy (NRT), Gamma-Tocopherol, Smoking cessation
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Smoking
Efficacy and Safety Study of Nicotine Mint Lozenge (2mg and 4mg) in Smoking Cessation
A multi-center, randomized, double-blind, placebo-controlled, 4-arm clinical study to evaluate efficacy and safety of nicotine lozenge (2mg and 4mg) in smoking cessation in adult cigarette smokers who are motivated to quit…
- Trial name
- NCT00985985
- Testing
- Nicotine
- Volunteers
- 723 people
- Sponsor
- GlaxoSmithKline
Nicotine Addiction
Comparative Effectiveness of Cystine Versus Nicotine Replacement Therapy
A pragmatic, single blinded, randomized, controlled non-inferiority trial of Cytisine versus Nicotine Replacement Therapy for continuous abstinence is conducted in the government run primary health hospitals in Mongolia.
- Trial name
- NCT04126135
- Testing
- Cytisine, Nicotine Replacement Therapy (NRT)
- Where
- Mongolia
- Volunteers
- 1,307 people
- Sponsor
- Loma Linda University
Tobacco Use Cessation
Improving Varenicline Adherence and Outcomes in Homeless Smokers
the purpose of the study is to see if varenicline in combination with motivational counseling helps homeless cigarette smokers quit smoking.
- Trial name
- NCT00786149
- Testing
- Varenicline plus Motivational Interviewing counseling, Varenicline without counseling
- Where
- United States
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking
Phase I Study: Stop Smoking Therapy for Ontario Patients (STOP)
20% of Ontarians smoke. There was a decline in smoking prevalence from 1995 but it has remained unchanged since 2002. This rate of smoking cessation has not kept up with the rest of Canada.
- Trial name
- NCT00356993
- Testing
- Nicotine Replacement Therapy, behavioural intervention
- Where
- Canada
- Volunteers
- 6,009 people
- Sponsor
- Centre for Addiction and Mental Health
Smoking, Nicotine Addiction
The END Perioperative Smoking Pilot Study
The purpose of this pilot randomized trial is to determine the feasibility of e-cigarettes and telephone counselling (compared to transdermal nicotine replacement and telephone counselling) as a harm-reduction tool that may lead…
- Conditions
- Smoking, Nicotine Addiction, Surgery
- Trial name
- NCT02482233
- Testing
- ENDD (NJOY), NRT (NicoDerm CQ), telephone counseling
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Smoking Cessation
Provoked Craving Relief Study by NRT
This study is designed to assess the ability of the mint nicotine mouth strip to relieve provoked cigarette craving in light smokers compared to nicotine lozenge and nicotine gum.
- Trial name
- NRT (NCT01476202)
- Testing
- nicotine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Smoking Cessation
Pilot Study of a New Nicotine Replacement Therapy
Pilot study of a new nicotine replacement therapy for smoking cessation.
- Trial name
- NCT00764439
- Testing
- Nicotine replacement therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 258 people
- Sponsor
- McNeil AB
Growth Hormone Deficiency
A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin
The goal of this study is to further characterise the potential long-term safety risks of lonapegsomatropin in patients treated with lonapegsomatropin under real-world conditions in the post-marketing setting.
- Trial name
- SkyPASS (NCT05775523)
- Testing
- No intervention
- Where
- 27 sites in United States
- Volunteers
- 500 people
- Sponsor
- Ascendis Pharma Endocrinology Division A/S
Bladder Cancer, Cervical Cancer
Varenicline or Nicotine Patch and Nicotine Gum in Helping Smokers in a Methadone Treatment Program Stop Smoking
RATIONALE: Varenicline, the nicotine patch, and nicotine gum help people stop smoking. It is not yet known whether varenicline is more effective than the nicotine patch given together with nicotine gum in helping smokers quit…
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00790569
- Testing
- nicotine, varenicline
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- Butler Hospital
Tobacco Use Cessation
Offering Proactive Tobacco Treatment
This study uses a proactive outreach strategy, coupled with free nicotine replacement therapy (NRT) to increase the population impact of tobacco cessation treatment for diverse, low income smokers.
- Trial name
- NCT01123967
- Testing
- proactive outreach (PRO), telephone counseling (TC), Nicotine replacement therapy (NRT)
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Use Disorder
Nicotine Replacement Therapy Prescribing and Lung Cancer Screening in Hospitalized Patients
Investigators are evaluating an EHR-based, non-interruptive alert to increase NRT prescribing in the hospital and at discharge for hospitalized patients.
- Trial name
- NCT07164404
- Testing
- EHR alert
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Medical University of South Carolina
Nicotine Dependence
Evaluation of Moclobemide, a Reversible MAO-A Inhibitor, as an Adjunct to Nicotine Replacement Therapy in Female Smokers
The proposed study will assess the efficacy of moclobemide, a selective, reversible MAO-A inhibitor, in facilitating smoking cessation in treatment-seeking female smokers.
- Trial name
- RIMA (NCT01926626)
- Testing
- Nicotine Patch, Moclobemide
- Where
- 3 sites in United States
- Volunteers
- 76 people
- Sponsor
- Jed E. Rose
Smoking Cessation
Effect of Pre-op NRT on Peri-operative Complications and Long-term Abstinence: A Pilot Trial in Patients Undergoing CABG Surgery
This study will determine whether or not patients who use a Nicotine Replacement Therapy (NRT) patch prior to their by-pass surgery are more likely to be smoke-free 6 months after their surgery and have fewer post-operative…
- Trial name
- NCT02918500
- Testing
- Nicoderm Patch
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Smoking
Behaviorally Enhanced Counseling on Nicotine Dependence (BEACON) Trial.
The major purpose of this exploratory developmental study will be to develop a patient-centered and feasible protocol for communicating genetic data as it relates to drug efficacy for smoking cessation inpatients receiving…
- Trial name
- NCT00991081
- Testing
- Counseling, Self-help guide, Pharmacotherapy
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Stanford University