Clinical trials: Nicotine Vaping
Nicotine Dependence, Nicotine Dependence, Cigarettes
Comparing the Pharmacokinetics of Nicotine Salt Based ENDS in Healthy Smokers
A Ten Sequence, Open Label, Randomized Crossover Study Comparing Nicotine Pharmacokinetics of JUUL 1.7% and JUUL 5% Nicotine Salt Based ENDS Products, in Healthy Adult Smokers.
- Conditions
- Nicotine Dependence, Nicotine Dependence, Cigarettes, Tobacco Use, Tobacco Smoking
- Trial name
- NCT03593239
- Testing
- Tobacco flavored JUUL 1.7% ENDS, Tobacco flavored JUUL 5% ENDS, Mint flavored JUUL 1.7% ENDS
- Where
- New Zealand
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Juul Labs, Inc.
Smoking Cessation, Cardiovascular Diseases
E-cigarettes and Cardiovascular Function
The large current uptake of e-cigarettes (2.8 million U.K. users in 2016; 26), the continuous involvement of e-cigarettes (which potentially affects their contents as well), the uncertainty about their medium- and longer-term…
- Conditions
- Smoking Cessation, Cardiovascular Diseases, Microcirculation, Macrocirculation
- Trial name
- ISME-NRT (NCT03061253)
- Testing
- Electronic Cigarette and behavioural change support., Nicotine-Free Electronic Cigarette and behavioural change support., Nicotine Replacement Therapy and behavioural change support.
- Where
- United Kingdom
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Cardiovascular Risk Factor, Nicotine Dependence
Short-Term Cardiovascular Effects of E-Cigarettes: Influence of Device Power
This study will examine the short-term cardiovascular (CV) effects of e-cigarette device power in a randomized, crossover clinical and behavioral pharmacology study of experienced adult e-cigarette users (N=21).
- Trial name
- TCORS-1 (NCT03839745)
- Testing
- Electronic Cigarette
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking Cessation, Smoking
Implementation and Dissemination of an Evidence-Based Tobacco Product Use Prevention Videogame Intervention With Adolescents
To examine the effects on participants who play the smokeSCREEN game in that the game will have positive changes in their attitudes, beliefs, knowledge, intentions, behaviors and other outcomes related to smoking and tobacco…
- Trial name
- NCT03815591
- Testing
- smokeSCREEN web-based game
- Where
- United States
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Yale University
E-cigarette Use, Substance Use
The Development and Evaluation of a Culturally Grounded ENDS Intervention for Rural Hawaiian Youth
The purpose of this research proposal is to develop and evaluate a culturally grounded, ENDS prevention intervention for rural Hawaiian youth. This will be accomplished through two specific aims.
- Trial name
- NCT06929520
- Testing
- ENDS Prevention Intervention (TBD)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
E-Cig Use
Respiratory Effects of E-Cigarettes in Obese Youth
To determine vaping behaviors and respiratory function in obese and nonobese youth e-cigarette users.
- Trial name
- RESEC (NCT05869318)
- Testing
- ECIG own, ECIG Vuse
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cough
Effect of Electronic Cigarette Use on Cough Reflex Sensitivity
Although electronic cigarettes (e-cigs) are now widely used, very little information exists regarding the effect of electronic cigarette use (vaping) on the respiratory system.
- Trial name
- NCT02203162
- Testing
- electronic cigarette exposure
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
THC, Cannabis
Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration
This is a crossover, randomized, double-blinded clinical pharmacology study enrolling dual cannabis-tobacco smokers to better understand the combined effects of co-administering cannabis and tobacco.
- Conditions
- THC, Cannabis, Cannabis Use, Cannabis Smoking
- Trial name
- CANNIC (NCT05999383)
- Testing
- Cannabis, Nicotine, Pax Loose Leaf Vaporizer
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking Cessation
The Use of Nicotine Patches Together With E-cigarettes (With and Without Nicotine) for Smoking Cessation
A randomised trial to determine whether e-cigarettes (with and without nicotine) combined with nicotine patches and behavioural support can assist smokers in remaining abstinent for at least six months.
- Trial name
- ASCEND-II (NCT02521662)
- Testing
- Nicotine patch, e-cigarette, Nicotine
- Where
- New Zealand
- Volunteers
- 1,124 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Adolescent Substance Use
Guiding Good Choices for Health
This study evaluates the feasibility and effectiveness of implementing Guiding Good Choices (GGC), an anticipatory guidance curriculum for parents of early adolescents, in three large, integrated healthcare systems.
- Trial name
- GGC4H (NCT04040153)
- Testing
- Guiding Good Choices
- Where
- 3 sites in United States
- Volunteers
- 3,636 people, healthy volunteers welcome
- Sponsor
- University of Washington
Vaping
A Virtual Reality Vaping Prevention Intervention for Adolescents
This study will examine E-Invite Only VR, a novel school-based universal e-cigarette prevention intervention that uses virtual reality (VR) to deliver prevention and emotion regulation skills-building content to middle school…
- Trial name
- NCT07362069
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking, Cigarette, Smoking Cessation
Feasibility of a Decision Aid for E-Cigarettes in Primary Care
The study team will use a pre-post study design, in which data will be collected from 60 patients under "control" conditions (Phase I), whereby an iPad-delivered decision aid is implemented in the clinic to address only standard…
- Trial name
- NCT03836573
- Testing
- Smoking Cessation iPad Decision Aid Tool
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Florida
E-Cig Use
Understanding the Impact of Cartridge-Based Electronic Cigarettes and Generated Aerosols on Cardiopulmonary Health
Over the last decade, e-cigarettes have become increasingly popular, due to their promotion as a healthy alternative to traditional tobacco cigarettes.
- Trial name
- NCT05199480
- Testing
- Tobacco flavored liquid type 1, Tobacco flavored liquid type 2
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Electronic Cigarette Use, Pulmonary Disease
Factors That Impact the Relationship Between Pulmonary Status and Susceptibility to Electronic Cigarette Use
The purpose of the study is to explores various psycho-social, physiological, cognitive, behavioral, and environmental factors that may affect the association between pulmonary status and Susceptibility to Electronic Cigarette Use
- Trial name
- NCT04151784
- Testing
- Pulmonary Group, Healthy Control
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Electronic Cigarette Use
Effect of Menthol on ENDS Users' Addiction and Exposure
The use of electronic nicotine delivery systems (ENDS; e-cigarettes) has reached epidemic levels among young people in the United States (US).
- Trial name
- NCT05338801
- Testing
- Menthol-flavored e-cigarette, Tobacco-flavored e-cigarette
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Florida International University
Tobacco-Related Carcinoma
Nicotine and Tobacco Message Framing to Change Smoking Behavior in Diverse Groups of Young Adult Smokers
This clinical trial evaluates the effect of message framing on smoking behaviors among lesbian, gay, bisexual, transgender, queer (LGBTQ+) young adults who use nicotine and/or tobacco.
- Trial name
- NCT06644664
- Testing
- Health Education, Interview, Smoking Cessation Intervention
- Where
- United States
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
E-Cig Use
The Impact of Policies Regarding E-cigarette on Adolescents and Young Adults' Cognition and Behavior for E-cigarette
Based on the Knowledge，Attitude，Belief and Practice model(KABP model), this study intends to use a mixed method to explore the influencing mechanism of youth and adolescents' cognition and behavior for e-cigarette before and…
- Trial name
- NCT05482581
- Testing
- Questionnaires set
- Where
- China
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Vaping Related Disorder
Radiology and BAL in Vaping Associated Lung Injury
Radiology and BAL in Vaping associated lung disease
- Trial name
- NCT07499557
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Healthy Lifetime Non-smokers
Evaluation of Acute and Subacute Effects of Nicotine Free Electronic Cigarette(NCFE) Vapors
This aim will examine the acute and subacute exposures to electronic cigarette (EC) vapor generated from e-liquids without nicotine (NFEC) on life-time non smokers subjects by measuring changes in nasal ion transport and TGF-β…
- Trial name
- NCT02585791
- Testing
- Propylene Glycol, vegetable glycerin, PG+VG
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Miami
Vaping, E-Cig Use
A Study of Cytisinicline for Vaping Cessation in Adult Smokers
This placebo-controlled Phase 2 study is being conducted at sites within the United States to evaluate the efficacy and safety profile of 3 mg cytisinicline administered TID for 12 weeks for vaping cessation.
- Trial name
- ORCA-V1 (NCT05431387)
- Testing
- cytisinicline, Behavioral support
- Where
- 5 sites in United States
- Volunteers
- 160 people
- Sponsor
- Achieve Life Sciences