Clinical trials: Nightmares
Narcolepsy, Narcolepsy Type 1
Narcolepsy Nightmare Study
The goal of this clinical trial is to test two behavioral treatments for nightmares in adults with narcolepsy. The main questions it aims to answer are: Is imagery rehearsal therapy (IRT) effective for narcolepsy-related…
- Conditions
- Narcolepsy, Narcolepsy Type 1, Narcolepsy With Cataplexy, Narcolepsy Type 2
- Trial name
- NCT05709873
- Testing
- Imagery rehearsal therapy, Targeted dream control
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Northwestern University
Nightmare, Suicidal Ideation
Cognitive-Behavioral Therapy for Children With Nightmares
The goal of this clinical trial is to assess the efficacy of CBT-NC intervention to determine its impact on mental health and suicidality in children ages 6-17.
- Conditions
- Nightmare, Suicidal Ideation, Children, Only
- Trial name
- NCT06033781
- Testing
- Cognitive Behavioral Therapy for Nightmares in Children
- Where
- 2 sites in United States
- Volunteers
- 57 people
- Sponsor
- University of Oklahoma
Nightmare
Cognitive-Behavioral Therapy for Children With Nightmares as a Mediator of Suicide Risk (COMAA)
Youth suicide risk has increased 56% in the last decade, and suicide is the leading cause of preventable death in children and adolescents.
- Trial name
- COMAA (NCT05588739)
- Testing
- Cognitive Behavioral Therapy
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- University of Oklahoma
Nightmare
Cognitive Behavioral Therapy for Nightmares in Children
Up to 50% of children experience nightmares annually. Nightmares interfere with sleep quality and quantity resulting in sleep deficiency, and are associated with negative mental health consequences.
- Trial name
- CBT-NC (NCT04047277)
- Testing
- Cognitive Behavioral Therapy
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- University of Oklahoma
Post Traumatic Stress Disorder, Suicidal Ideation
Reducing Suicidal Ideation Through Treatment of Nightmares-Post Traumatic Stress Disorder (PTSD)
Patients with PTSD, and frequent nightmares, and mild-moderate suicidal ideation, who are already taking a Selective Serotonin Reuptake Inhibitor (SSRI) or Serotonin Norepinephrine Reuptake Inhibitor (SNRI) will be randomized to…
- Conditions
- Post Traumatic Stress Disorder, Suicidal Ideation, Nightmares
- Trial name
- REST-ON PTSD (NCT02199652)
- Testing
- Prazosin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Augusta University
Stress Disorders, Post-Traumatic, Bulimia Nervosa
Effectiveness of Prazosin in Bulimic Patients Experiencing Nightmares Due to PTSD
This research is being done to find out how effective Prazosin is in the treatment of bulimic patients experiencing distressing nightmares using subjective and objective measures.
- Trial name
- NCT02382848
- Testing
- Prazosin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Milton S. Hershey Medical Center
Nightmares
Treatment of Nightmares Via the Internet
This study is a randomized controlled trial (RCT) to evaluate the effect of an internet-based, guided self-help treatment of reoccurring and distressing nightmares.
- Trial name
- MARI (NCT01502930)
- Testing
- IRT, Stress Reduction
- Where
- Sweden
- Volunteers
- 175 people
- Sponsor
- Karolinska Institutet
Nightmares, Post-traumatic Stress Disorder
Brief Treatment for Trauma Nightmares in Trauma-exposed Adults With Bipolar Disorder
Exposure, relaxation, and rescripting therapy (ERRT) is a promising psychological intervention developed to target trauma-related nightmares and sleep disturbances.
- Trial name
- BERRT (NCT02242110)
- Testing
- ERRT-Bipolar Disorder
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Tulsa
Nightmares Associated With Trauma and Stress
Exposure, Relaxation, & Rescripting Therapy-Child
Untreated trauma-related nightmares and sleep-related disorders are associated with chronic health problems, burdening both the suffering individual and the health-care system.
- Trial name
- ERRT-C (NCT01776229)
- Testing
- Exposure, Relaxation, & Rescripting Therapy-Child
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Tulsa
PTSD - Post Traumatic Stress Disorder, Trauma-related Nightmares
Validation of an Algorithm for Predicting Awakenings Associated With Trauma-related Nightmares, Based on the Analysis of Physiological Patterns in Military and Former Military Patients Suffering From Post-traumatic Stress Disorder
The goal of this clinical trial is to validate an artificial intelligence algorithm called CAUD-PIN (CAUchemar Detection on INdividualized Parameters) to predict nightmare-related awakenings in military personnel and veterans…
- Trial name
- CAUD-PIN (NCT07851480)
- Testing
- CAUD-PIN (CAUchemar Detection on INdividualized Parameters) - AI-based predictive algorithm forTrauma-related nightmare awakenings
- Where
- 3 sites in France
- Volunteers
- 27 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Nightmares, REM-Sleep Type
Combined Treatment of Nightmares With Targeted Memory Reactivation and Imagery Rehearsal Therapy
With this protocol, investigators examine whether targeted memory reactivation (TMR), a technique used to strengthen memories, can accelerate remission of nightmare disorder.
- Trial name
- NCT05237778
- Testing
- Imagery Rehearsal Therapy and Targeted memory reactivation during REM sleep, Imagery Rehearsal Therapy
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University Hospital, Geneva
PTSD, Sleep Disorders
Cooperative Studies Program #563 - Prazosin and Combat Trauma PTSD
Background: Posttraumatic stress disorder (PTSD) is a debilitating and disabling mental disorder that afflicts at least 25% of Veterans who have suffered life-threatening war zone trauma.
- Trial name
- PACT (NCT00532493)
- Testing
- prazosin
- Where
- 15 sites in United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stress Disorders, Post-Traumatic, Sleep Disorders
Prazosin vs Paroxetine in Combat Stress-Related Post-Traumatic Stress Disorder (PTSD) Nightmares & Sleep Disturbance
The purposes of this study are: to evaluate the efficacy and tolerability of the drug prazosin compared to placebo for combat stress-related nightmares, sleep disturbance and overall function in recently combat-exposed returnees…
- Trial name
- NCT00202449
- Testing
- prazosin, paroxetine
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Nightmares
A Self-Help Method for Nightmares
The objective of this study is to validate a newly designed self-help treatment for nightmares. This self-help treatment is based on Imagery Rehearsal Therapy.
- Trial name
- Nightmares (NCT00513045)
- Testing
- IRT, Exposure
- Where
- Netherlands
- Volunteers
- 399 people, healthy volunteers welcome
- Sponsor
- Utrecht University
Nightmares, Insomnia
Treating Insomnia & Nightmares After Trauma: Impact on Symptoms & Quality of Life
Exposure to trauma, especially when it manifests as Posttraumatic Stress Disorder (PTSD), results in numerous negative consequences for patients, families, and society.
- Conditions
- Nightmares, Insomnia, Posttraumatic Stress Disorder
- Trial name
- NCT01009112
- Testing
- PTSD + IRT/CBT-I, PTSD + Supportive Care Therapy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of California, San Diego
Insomnia, Nightmares Associated With Trauma and Stress
Restorative Early Sleep Treatment After the Emergency Department
The goal of this randomized controlled trial is to pilot the virtual delivery of cognitive behavioral therapy for insomnia (CBT-I) and nightmares (CBT-I\&N) via telehealth as an early intervention for treating posttraumatic sleep…
- Conditions
- Insomnia, Nightmares Associated With Trauma and Stress, Nightmares, PTSD - Post Traumatic Stress Disorder
- Trial name
- RESTED (NCT07121270)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Cognitive Behavioral Therapy for Insomnia and Nightmares, Sleep Education
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Henry Ford Health System
Nightmare, Psychiatric Disorder
Psychiatric Inpatient Nightmare Treatment
Nightmares are repeated extremely dysphoric and well-remembered dreams, which typically occur during REM sleep in the second half of sleep, may awaken the dreamer, and upon awakening, individuals quickly become oriented and…
- Trial name
- PINIT (NCT04198142)
- Testing
- Imagery Rehearsal Therapy, Treatment as Usual with dream diaries
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Zurich
Stress Disorder, Post-Traumatic
Prazosin Treatment for Combat Trauma PTSD (Post-Traumatic Stress Disorder) Nightmares and Sleep Disturbance
The purpose of this study is to determine whether prazosin will reduce the incidence of nightmares, sleep disturbance, and overall symptoms in combat trauma-exposed individuals with PTSD.
- Trial name
- NCT00108420
- Testing
- Prazosin
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Stress Disorders, Post-Traumatic
A Randomized Controlled Trial of Doxazosin for Nightmares, Sleep Disturbance, and Non-Nightmare Clinical Symptoms in PTSD
This randomized, double-blind, placebo-controlled trial of doxazosin will assess doxazosin's effectiveness for PTSD nightmares, subjective sleep quality, and non-nightmare PTSD symptoms in adult men and women veterans with full…
- Trial name
- NCT03339258
- Testing
- Doxazosin Mesylate, Extended Release
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- San Francisco Veterans Affairs Medical Center
Posttraumatic Stress Disorder
Predicting Responses to PTSD Treatment With Iris and Cardiovascular Tests
Post-traumatic stress disorder (PTSD) affects many individuals who experience a traumatic event. There are a variety of treatment options for PTSD, including psychotherapy (talk therapy) options, as well as medications, such as…
- Trial name
- PREDICT (NCT03539614)
- Testing
- Prazosin
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- VA Office of Research and Development