Clinical trials: Nightmares
Stress Disorders, Post-Traumatic, Sleep Initiation and Maintenance Disorders
A Transdiagnostic Sleep Health Intervention for Veterans With PTSD
Sleep disturbance is a major problem in Veterans with posttraumatic stress disorder (PTSD). This study will test a version of a sleep treatment that's been shown to be effective in the general population, with some changes to…
- Trial name
- NCT06549049
- Testing
- TranS-C for PTSD, Sleep Psychoeducation Control
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder, Sleep Disorders
Cognitive Behavioral Therapy (CBT) for Nightmares in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans
The purpose of this study is to compare the effectiveness of two talk therapies for OEF/OIF Veterans at the Michael J. Crescenz and the West Haven VA Medical Centers.
- Conditions
- Posttraumatic Stress Disorder, Sleep Disorders, Nightmares
- Trial name
- NCT00691626
- Testing
- CBT for Insomnia plus Imagery Rehearsal, CBT for Insomnia plus psychoeducation
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- VA Office of Research and Development
Sleep Terror, Sleepwalking
Development and Online Evaluation of an Online Course for Parasomnias
Parasomnias are unwanted events during sleep. These refer to sleep terrors, sleepwalking, sleep eating, nightmares, and movement during REM sleep.
- Conditions
- Sleep Terror, Sleepwalking, Nightmare Disorder, REM Sleep Behavior Disorder (iRBD)
- Trial name
- NCT07361315
- Testing
- Parasomnia Education, Sleep Hygiene Control
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Stress Disorders, Post-Traumatic, Combat Disorders
Augmentation Trial of Prazosin for Post-Traumatic Stress Disorder (PTSD)
The purpose of this study is to determine whether prazosin will: reduce the incidence of nightmares and sleep disturbance increase functioning and sense of well being in combat-trauma exposed Operation Iraqi Freedom/Operation…
- Conditions
- Stress Disorders, Post-Traumatic, Combat Disorders, Sleep Disorders
- Trial name
- NCT00990106
- Testing
- prazosin hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 67 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
PostTraumatic Stress Disorder, Sleep Disorder
Remote Study of NightWare for PTSD With Nightmares
This study will provide measures of safety and efficacy of the NightWare digital therapeutic system (iPhone + Apple watch + proprietary application) for the treatment of nightmare disorder associated with post-traumatic stress…
- Conditions
- PostTraumatic Stress Disorder, Sleep Disorder, Stress Disorder, Sleep Initiation and Maintenance Disorders
- Trial name
- NWVRCT (NCT03934658)
- Testing
- NightWare Therapeutic System
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- NightWare
Nightmares, Stress Disorders, Post-Traumatic
Understanding Trauma Nightmares Using In-Home Measurement
Trauma-related nightmares in Veterans are associated with poor clinical outcomes, greater substance use, and increased risk of suicide.
- Conditions
- Nightmares, Stress Disorders, Post-Traumatic, Actigraphy, Respiratory Sinus Arrhythmia
- Trial name
- NCT03974503
- Testing
- Exposure, Relaxation, and Rescripting Therapy, Sleep and Nightmare Management
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- VA Office of Research and Development
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Stress Disorders, Post-Traumatic
A Pilot Study to Assess the Effects of Doxazosin on Polysomnography in PTSD
This study will assess the effects of the medication doxazosin on sleep in men and women with PTSD. Sleep will be measured objectively at home using a portable sleep recorder and wrist actigraphy.
- Trial name
- NCT01959022
- Testing
- Doxazosin XL
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- San Francisco Veterans Affairs Medical Center
PTSD
The Nightmare Augmented Protocol for Treatment of Nightmares in Veterans With PTSD
The primary goal of this study is to determine whether the use of a timed tone played during sleep, in addition to the use of established therapies, will reduce or eliminate the occurrence of nightmares.
- Trial name
- NAP (NCT05120674)
- Testing
- NAP, CPT, ERRT
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- VA Eastern Kansas
Stress Disorders, Post-Traumatic, Combat Disorders
Traumatic Nightmares Treated by NightWare (To Arouse Not Awaken)
This study will provide preliminary estimates of safety and efficacy of the NightWare digital therapeutic system (iPhone + Apple watch + proprietary application) for the treatment of nightmare disorder associated with…
- Conditions
- Stress Disorders, Post-Traumatic, Combat Disorders, Ptsd, Nightmare
- Trial name
- TNT/NW (NCT03795987)
- Testing
- NightWare Therapeutic System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NightWare
Frequent Trauma-related Nightmares
Dismantling Exposure, Relaxation, and Rescripting Therapy
The purpose of this case series dismantling study is to extend previous findings regarding the efficacy of a brief treatment for chronic post-trauma nightmares by examining the dose effect and mechanism of change.
- Trial name
- ERRT (NCT02236377)
- Testing
- Exposure, Relaxation, and Rescripting Therapy
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Tulsa
Post Trauma Nightmares, Traumatic Stress
Exposure, Relaxation, & Rescripting Therapy-Child
The study implements a trauma-related nightmare treatment for children aged 8 to 13 years. Relevant outcome progress and outcome measures on symptoms, nightmare distress and duration, academic indicators, and sleep quality will…
- Trial name
- ERRT-C (NCT02184026)
- Testing
- Exposure, Relaxation, & Rescripting Therapy-Child
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Montana