Clinical trials: Nitrate
Dentine Hypersensitivity
Efficacy of Potassium Nitrate Solution in Reducing Dentinal Hypersensitivity
An exploratory study investigating the direct application of potassium nitrate (KNO3) solutions of different concentrations in reducing dentine hypersensitivity.
- Trial name
- NCT01115452
- Testing
- 5% Potassium nitrate, 2.5% Potassium nitrate, Sterile water
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- GlaxoSmithKline
Fontan
Nitrate Effect on Exercise Capacitance
The investigators will investigate the safety and preliminary efficacy of ISDN therapy to reduce venous congestion and improve exercise tolerance in children and adults after the Fontan operation.
- Trial name
- NEET (NCT04297241)
- Testing
- Isosorbide Dinitrate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Type 2 Diabetes
Nitrate Supplementation and Exercise Tolerance in Patients With Type 2 Diabetes
The purpose of this study is to use a randomized, double-blind, placebo controlled study design to comprehensively investigate the impact of 8-weeks of dietary nitrate supplementation on skeletal muscle blood flow, mitochondrial…
- Trial name
- NCT02804932
- Testing
- Super Beets
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Darren P Casey
Cystic Fibrosis
A Pharmacokinetic and Safety Study of IV Gallium Nitrate (Ganite) in Cystic Fibrosis Patients
The purpose of this research study is to test the pharmacokinetics, safety, and tolerability of an intravenous infusion of a drug called Ganite (gallium nitrate) in patients with cystic fibrosis.
- Trial name
- NCT01093521
- Testing
- 100 mg/m2 dose, 200 mg/m2 dose
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Asthma
The Effects of NOx and Conjugated Linoleic Acid on Asthmatics
This study will examine the hypothesis that in obese asthmatics; treatment with NOx + CLA is well tolerated, safe and will increase eNO while reducing airway oxidative stress.
- Trial name
- NICLA (NCT02433977)
- Testing
- Conjugated Linolenic Acid, Sodium Nitrite, Sodium Nitrate
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Gladwin, Mark, MD
Hypertension
The Chronic Effects of Beetroot Juice in Hypertensive Subjects
We are interested in the effect of diet on blood pressure. Our previous research has shown that beetroot juice lowers blood pressure in healthy people.
- Trial name
- NCT01405898
- Testing
- beetroot juice, Nitrate-free beetroot juice
- Where
- United Kingdom
- Volunteers
- 68 people
- Sponsor
- Queen Mary University of London