Clinical trials: Nitrate, active
Athletic Performance, Dietary Supplement
The Effects of Acute Nitrate and Caffeine Co-ingestion on Discipline-Specific Exercise Performance.
The purpose of this study is to investigate the acute, separate, and combined ergogenic effects of dietary nitrate (beetroot juice, BJ) and caffeine (CAF) supplementation on discipline-specific athletic performance.
- Conditions
- Athletic Performance, Dietary Supplement, Iron Status
- Trial name
- NCT07748416
- Testing
- Caffeine, Dietary Nitrate (Beetroot Juice)
- Where
- Poland
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Kidney Injury, Acute
Inorganic Nitrate (NaNO3) Prevention of Contrast-Associated Acute Kidney Injury
This pilot study is designed to test the logistics and recruitment of a trial testing the benefit of sodium nitrate in the prevention of contrast-associated kidney injury in a group of patients at high-risk.
- Trial name
- NCT07016074
- Testing
- Sodium Nitrate
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease
Pilot Study of Nitrate-rich Beetroot Juice Supplementation in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Idiopathic pulmonary fibrosis (IPF) is a type of scarring (fibrotic) lung disease. Reduced exercise capacity is a key symptom experienced by patients.
- Trial name
- BEET-IPF (NCT06488638)
- Testing
- nitrate-rich beetroot juice (70ml with approx. 400 mg nitrate) twice a day for 3 days
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Hypertensive Heart Disease Without (Congestive) Heart Failure
The Influence of Beetroot Powder at a Dose of 20 g on Blood Pressure, Microcirculation, and Biochemical Markers in Men With Arterial Hypertension.SVEKLA2025.
Objective: to evaluate the effectiveness of using a food product, dry finely dispersed beetroot powder in a dose of 20 g, containing 800 mg of nitrate (NO3-), in relation to the regulation of blood pressure in men with…
- Trial name
- NCT07270718
- Testing
- Plus SVEKLA
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Repeated Sprint Performance in Trained Athletes, Exercise Performance
Beetroot Beverage and Repeated Sprint Power Output During RAST
This randomized, double-blind, placebo-controlled crossover trial aims to evaluate the acute effects of a nitrate-rich beetroot-based beverage on repeated sprint performance in trained athletes.
- Conditions
- Repeated Sprint Performance in Trained Athletes, Exercise Performance, Nitrate Supplementation
- Trial name
- NCT07473193
- Testing
- Beetroot-based antioxidant beverage
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Chihuahua
Heavy Drinking
Study of Nitrate-Rich Juice on Cognitive Function in Heavy Alcohol Drinkers: a Two-Stage Adaptive Design Real-World Clinical Trial
It is known that alcohol consumption can lead to cognitive impairment and dysregulation of inflammatory responses. A preliminary randomized controlled trial conducted by our research team has suggested that nitrate may improve…
- Trial name
- NCT06777459
- Testing
- Nitrate-rich beetroot juice
- Volunteers
- 43 people
- Sponsor
- Peking University Sixth Hospital
Heart Failure With Reduced Ejection Fraction
Neuromuscular Fatigability in Individuals With Heart Failure
Brief summary The aims of this project are to 1) characterise muscle fatigue in individuals with chronic heart failure during exercise involving a smaller and larger muscle mass (Part I), 2) to determine the effect of nitrate…
- Trial name
- NCT06551012
- Testing
- Nitrate-rich beetroot juice, Beetroot juice with nitrate extracted
- Volunteers
- 28 people
- Sponsor
- Newcastle University
Hypertension, Hypertension (HTN)
Effects of Beetroot Extract on Blood Pressure and Exercise in Hypertensive Older Women
The goal of this clinical trial is to learn about the acute effects of beetroot extract in older women with high blood pressure.
- Trial name
- NCT07444138
- Testing
- Beetroot Extract (Nitrate-rich), Exercise, Rest (Control Condition)
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Healthy
Beetroot Juice and Sleep
The purpose of this study is to investigate the effects of acute inorganic nitrate supplementation (with beetroot) on the regulation of sleep and neurovascular physiology.
- Trial name
- NCT05864521
- Testing
- Active Beetroot Juice Supplement (aBRJ)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Primary Hypertension
Dietary Nitrate and the Oral Microbiome in Children With Primary Hypertension
Children and adolescents with primary hypertension (high blood pressure without an underlying secondary cause) are at increased risk of cardiovascular disease in adulthood.
- Trial name
- NCT07236125
- Testing
- No active intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Yelda Kasımoğlu
Menopause
Exercise Training Intensity and Nitrate Supplementation in Post-Menopausal Females
Menopause greatly increases cardiovascular disease risk (CVD). Current exercise guidelines are inadequate to ameliorate this risk and higher intensity exercise may be necessary for cardiovascular benefits in postmenopausal…
- Trial name
- NCT06480695
- Testing
- Nitrate-Rich Beetroot Juice, High Intensity Exercise, Moderate Intensity Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Healthy, Older Adults
The Combined Effect of Dietary Nitrate and Caloric Restriction on Cognitive and Vascular Function.
This pilot study will compare the effect of combining dietary nitrate and caloric restriction versus dietary nitrate alone. The participant will be contacted, having responded to an advertisement on social media and posters, to…
- Conditions
- Healthy, Older Adults, Overweight and Obesity
- Trial name
- CRNitrateMRI (NCT06151015)
- Testing
- Nitrate-rich beetroot juice plus calorie-restricted diet, Nitrate-rich beetroot juice plus weight-maintenance diet
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Moira Taylor
Bronchoscopic Lung Volume Reduction
Bronchoscopic Lung Volume Reduction in Management of Localized Emphysema
Emphysema is a progressive phenotype of chronic Obstructive Pulmonary Disease (COPD), poses a significant global health burden characterized by irreversible lung parenchymal destruction and airspace enlargement.
- Trial name
- NCT06629558
- Testing
- Silver Nitrate, Nano-silver nitrate, Bronchoscopic lung volume reduction
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University Hospital
Healthy Adults, Mechanical Ventilation Dependence
Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude
This study investigates whether respiratory muscle training (RMT) and dietary nitrate supplementation can improve exercise tolerance under simulated moderate altitude conditions.
- Conditions
- Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training
- Trial name
- NCT07216755
- Testing
- Respiratory Muscle Training (RMT), Dietary Supplement: Beetroot Juice Concentrate
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Embry-Riddle Aeronautical University
Healthy, Menopause
Nitrate, Exercise and Vascular Function in Midlife Women
The purpose of this clinical study in women after menopause is to investigate whether the daily intake of nitrate from beetroot juice over 12 weeks enhances the positive effect of exercise training on vascular function, blood…
- Conditions
- Healthy, Menopause, Hypertension, Inflammation
- Trial name
- Women's-Beet (NCT06527248)
- Testing
- Nitrate group
- Where
- Austria
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Vital Pulp Therapies, Pulpotomy
Clinical and Radiographic Evaluation of Potassium Nitrate in Polycarboxylate Versus Mineral Trioxide Aggregate in Vital Pulpotomy in Primary Molars
The purpose of this RCT is to compare the clinical/radiographic outcomes of Potassium nitrate in polycarboxylate cement and MTA as pulpotomy biomaterials used for asymptomatic vital primary lower second molar and this will help…
- Conditions
- Vital Pulp Therapies, Pulpotomy, Pulp Disease, Dental, Pulpotomies Primary Teeth
- Trial name
- NCT06871709
- Testing
- Potassium Nitrate in Polycarboxylate cement, MTA-Anglus
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Arterial Hypertension, Resistant Hypertension
Effect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients
Arterial hypertension (AH) has been identified as an important public health problem and considered a new epidemic with high mortality and morbidity.
- Conditions
- Arterial Hypertension, Resistant Hypertension, Microvascular Function, Nitrate Supplementation
- Trial name
- NCT06169241
- Testing
- Beetroot extract
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Males, Females
Interaction Between Inorganic Nitrate Supplementation and Metformin in Individuals With Prediabetes
This study is examining whether short-term supplementation with inorganic nitrate, in the form of beetroot juice, can enhance blood vessel health, insulin sensitivity, and exercise capacity in individuals with prediabetes.
- Conditions
- Males, Females, Sedentary, Metformin
- Trial name
- NO3-PreDM (NCT07131384)
- Testing
- Dietary Supplement: Inorganic Nitrate (Beetroot juice)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Virginia
Tinea Pedis
Efficacy of Tropical Sertaconazole Nitrate 2% Vs Clotrimazole 1% for Tinea Pedis
This randomized controlled trail study will be carried out on OPD patients in the Department of Dermatology, Jinnah Postgraduate Medical Center.
- Trial name
- NCT06869681
- Testing
- Topical Sertaconazole 2%, Clotrimazole 1%
- Volunteers
- 100 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Chronic Paronychia
Safety and Efficacy of Intralesional 0.5% Triamcinolone Acetonide in 0.2% Fluconazole Solution vs 0.1% Topical Mometasone Furoate With 2% Miconazole Nitrate Cream in the Treatment of Chronic Paronychia: An Intraindividual Randomized Controlled Trial.
Our objective is to compare the efficacy and safety of intralesional corticosteroids + fluconazole solution to corticosteroid with an antifungal topical preparation, in the management of chronic paronychia.
- Trial name
- NCT07311759
- Testing
- Intralesional triamcinolone acetonide and fluconazole, Topical mometasone furoate and miconazole nitrate, Elica-M®
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cairo University