Clinical trials: No Condition
Inguinal Hernia Without Obstruction or Gangrene
Closed Suction Drain vs no Drain on Symptomatic Seroma Formation After Laparoscopic Inguinal Hernia Repair
The current study aims to determine whether a use of closed suction drain following laparoscopic inguinal hernia surgery performed for an inguinoscrotal variety can decrease the incidence of symptomatic seroma formation requiring…
- Trial name
- SALHS (NCT03563092)
- Testing
- Laparoscopic Inguinal Hernia (TEP/TAPP) Surgery
- Where
- India
- Volunteers
- 100 people
- Sponsor
- GEM Hospital & Research Center
Spina Bifida
The Study Aims to Improve the Accuracy of Detecting Spina Bifida During Early Ultrasound Scans. to Achieve This, an AI Model Has Been Developed to Provide Feedback About the Presence of Spina Bifida. a RCT Has Been Designed to Compare the Effectiveness of AI Feedback with No AI Feedback.
The study aims to improve the accuracy of detecting spina bifida during early ultrasound scans. To achieve this, an AI model has been developed to provide feedback about the presence of spina bifida.
- Trial name
- NCT06566014
- Testing
- Evaluation of XAI-assisted spina bifida diagnosis
- Where
- Denmark
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Diabetes Mellitus
Dose Modification Requirement for Trelagliptin in Egyptian Population
The proposed study will consider the pharmacokinetic evaluation of Trelagliptin after administration to Egyptian volunteers and the results will be compared with the other reported ethnic populations.
- Trial name
- Trelagliptin (NCT04374864)
- Testing
- Trelagliptin
- Where
- Egypt
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Chronic Obstructive Pulmonary Disease (COPD)
Nitric Oxyde Concentration in Chronic Obstructive Pulmonary Disease Patients - SANOB Study
Among many other causes, Bronchial obstruction in Chronic Obstructive Pulmonary Disease (COPD) is also caused by inflammation of peripheral airways walls.
- Trial name
- SANOB (NCT01853787)
- Testing
- Formoterol Fumarate, Salmeterol
- Where
- 2 sites in Italy
- Volunteers
- 49 people
- Sponsor
- University of Milan
Coronary Disease
Effects of Atorvastatin on Myonecrosis
This study is designed as a prospective, randomized, placebo-controlled, double-blind analysis of atorvastatin 80 mg versus placebo administered on average 4 hours prior to percutaneous coronary intervention [PCI] (at least 2…
- Trial name
- NCT00344019
- Testing
- Atorvastatin 80mg, Screening
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Beth Israel Deaconess Medical Center
Esophageal Neoplasms
Comparison of Captivator Tissue Cassettes vs. no Cassettes for Endoscopic Mucosal Resection in Esophageal Carcinoma
The main purpose of this study will be to two-fold; firstly to determine whether the use of a Captivator tissue cassette has an effect on the preservation of tissue histology (minimizing artifactual curling) , and secondly to…
- Trial name
- NCT02911363
- Testing
- Captivator cassette, Standard of Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- AdventHealth
No Conditions
Multistability: Perception is Inspired by Noise
Some stimuli, such as sinusoidal networks in motion, or the best known, Necker's cube, are simple visual stimulations generating interpretations of unstable and oscillatory shapes or movements, mutually exclusive.
- Trial name
- MUSPIN-B (NCT03723044)
- Testing
- EEG and occulometry
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
No Reflow Phenomenon, Anterior STEMI
Oral Nicorandil for Prevention of No Reflow Phenomenon in Anterior STEMI Patients Undergoing PPCI
Aim of the study is to Investigate the potential role of oral nicorandil in preventing the No reflow phenomenon in anterior ST-segment elevation myocardial infarction (STEMI) patients undergoing percutaneous coronary intervention…
- Trial name
- NCT07138508
- Testing
- Nicorandil 20mg
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Ain Shams University
Hyperbilirubinemia
Long-Term Clinical Follow-Up of Children Enrolled in Stannsoporfin Clinical Trial Protocol No. 64,185-06-2(W)
The purpose of this protocol is to provide a mechanism to collect Long Term Clinical Data from those babies who participated in the primary Study 64,185-06-2(W)(WS)(ISNHP) "An Open-Label Study Of The Safety And Clinical…
- Trial name
- NCT02685189
- Testing
- Previous exposure to stannsoporfin
- Volunteers
- 55 people
- Sponsor
- InfaCare Pharmaceuticals Corporation, a Mallinckrodt Company
Posttraumatic Stress Disorder (PTSD)
Trauma Suppression Training for Veterans
Intrusive memories of trauma are a core and often persistent symptom of posttraumatic stress disorder (PTSD). This study tested whether veterans with PTSD could take part in a computer-based training program that teaches people…
- Trial name
- TSTV (NCT07891559)
- Testing
- Web-based Think/No-Think retrieval-suppression training
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Palo Alto Veterans Institute for Research
Umbilical Hernia Repair
Topical Tranexamic Acid Spray Versus No Spray on Postoperative Outcomes Following Mesh Repair of Umbilical Hernia
Umbilical hernia is a type of ventral hernia that occurs commonly in adulthood, and mesh reinforcement is well established since there is a reduced recurrence rate when compared to suture repair.
- Trial name
- NCT07845370
- Testing
- Topical Tranexamic Acid Spray, No Topical Tranexamic acid
- Where
- Pakistan
- Volunteers
- 252 people
- Sponsor
- Dr Mudassar Saeed Pansota
High Risk Pregnancy
Impact of the NO-donor Pentaerythrithyltetrantrate on Perinatal Outcome in High-risk Pregnancies
Pregnancies resulting in IUGR and also in preeclampsia are strongly associated with typical underlying placental pathology revealing small placentas and maldevelopment of the decidual blood vessels, suggesting under-perfusion…
- Trial name
- NCT01355822
- Testing
- PETN
- Where
- Germany
- Volunteers
- 111 people
- Sponsor
- University of Jena
Type 2 Diabetes (Treated With Exenatide or Other Oral Antidiabetic Therapies), Healthy Subjects (Treated With no Diabetes Therapies)
A Retrospective Cohort Study of Acute Pancreatitis in Relation to Use of Exenatide and Other Antidiabetic Agents
The purpose of this research was to assess the absolute and relative incidence of acute pancreatitis in persons initiating exenatide compared with persons initiating a different antidiabetic agent, and secondarily, persons…
- Trial name
- NCT01077323
- Testing
- exenatide, Other antidiabetic therapies, No diabetes therapy
- Where
- United States
- Volunteers
- 363,766 people
- Sponsor
- AstraZeneca
Gastrointestinal Tumors, Surgical Wound Infection
Non-Dressing vs. Routine Dressing Change After Gastrointestinal Cancer Surgery
The goal of this randomized non-inferiority trial is to evaluate whether omitting postoperative wound dressings is noninferior to routine dressing changes in patients undergoing gastrointestinal cancer surgery.
- Conditions
- Gastrointestinal Tumors, Surgical Wound Infection, Pain, Postoperative
- Trial name
- Dressing (NCT06263205)
- Testing
- Non-Dressing of Surgical Wound, Regular Dressing Change of Surgical Wound
- Where
- 4 sites in China
- Volunteers
- 1,138 people
- Sponsor
- Fudan University
HIV Infections
A Study to Evaluate the Safety and Effectiveness of a New Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI), (+)-Calanolide A, in HIV-Positive Patients Who Have Never Received Anti-HIV Treatment
The purpose of this study is to test the safety and effectiveness of a new non-nucleoside reverse transcriptase inhibitor (NNRTI), (+)-calanolide A, in HIV-positive patients who have never received anti-HIV treatment.
- Trial name
- NCT00002243
- Testing
- Calanolide A
- Where
- 9 sites in United States
- Volunteers
- 32 people
- Sponsor
- Sarawak MediChem Pharmaceuticals
Prostate Cancer
Bicalutamide Compared With Observation Followed by Bicalutamide Plus Either Goserelin or Orchiectomy in Treating Patients With Prostate Cancer
RATIONALE: Testosterone can stimulate the growth of cancer cells. Bicalutamide and goserelin may fight prostate cancer by reducing the production of testosterone.
- Trial name
- NCT00014586
- Testing
- bicalutamide, goserelin acetate, orchiectomy
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Mild Cognitive Impairment, Coronary Heart Disease
Computerized Cognitive Training in Patients With Coronary Heart Disease and Mild Cognitive Impairment
In this study, a multicentre, double-blind, randomized controlled study based on cognitive training was conducted in patients with coronary heart disease and cognitive impairment but without dementia， to evaluate the…
- Trial name
- COG-T CHD (NCT05735041)
- Testing
- Multi-domain cognitive digital therapy, Basic cognitive therapy
- Where
- 8 sites in China
- Volunteers
- 224 people
- Sponsor
- Beijing Anzhen Hospital
Acute Myocardial Infarction, Percutaneous Coronary Intervention
Effects of Different Vasodilators on Coronary No-reflow During primAry percuTaneous Coronary intErvention in Patients With Acute Myocardial Infarction
The purpose of this study is to evaluate the efficacy of three different vasodilators including diltiazem, verapamil and nitroglycerin for reversal of no-reflow/slow-flow during direct percutaneous coronary intervention for acute…
- Trial name
- EDUCATE-AMI (NCT00712894)
- Testing
- Diltiazem, Verapamil, Nitroglycerin
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Fudan University
Sepsis, Respiratory Failure
The Effect of Intensive Insulin Therapy in the Surgical Critical Care Unit
We sought to determine if there is a benefit to using an insulin drip to control hyperglycemia in the surgical critical care unit for patients who undergo general and vascular surgery.
- Conditions
- Sepsis, Respiratory Failure, Renal Failure, Surgical Site Infection
- Trial name
- NCT00282594
- Testing
- Novolin R (human recombinant Insulin)
- Where
- United States
- Volunteers
- 317 people
- Sponsor
- Genesys
Healthy, no Evidence of Disease
Bowman-Birk Inhibitor Concentrate in Healthy Men
This randomized phase I trial is studying the side effects and best dose of Bowman-Birk inhibitor concentrate in healthy men. Chemoprevention is the use of certain drugs to keep cancer from forming.
- Trial name
- NCT00679094
- Testing
- Bowman-Birk inhibitor concentrate, pharmacological study, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)